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51

Prevention and reversal of hepatic steatosis with a high-protein diet in mice

Garcia-Caraballo, Sonia C., Comhair, Tine M., Verheyen, Fons, Gaemers, Ingrid, Schaap, Frank G., Houten, Sander M., Hakvoort, Theodorus B.M., Dejong, Cornelis H.C., Lamers, Wouter H., Koehler, S. Eleo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 1.61 MB

english, 2013

52

The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts

Houten, Sander, Auwerx, Johan

Journal:

Annals of Medicine

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

53

Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism

Pougovkina, Olga, te Brinke, Heleen, Wanders, Ronald J. A., Houten, Sander M., de Boer, Vincent C. J.

Journal:

Journal of Inherited Metabolic Disease

Year:

2014

Language:

english

File:

PDF, 418 KB

english, 2014

54

Fasting Serum Taurine-Conjugated Bile Acids Are Elevated in Type 2 Diabetes and Do Not Change With Intensification of Insulin

Wewalka, Marlene, Patti, Mary-Elizabeth, Barbato, Corinne, Houten, Sander M., Goldfine, Allison B.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 770 KB

english, 2014

55

Muscle MRI in patients with long-chain fatty acid oxidation disorders

Diekman, Eugene F., van der Pol, W. Ludo, Nievelstein, Rutger A. J., Houten, Sander M., Wijburg, Frits A., Visser, Gepke

Journal:

Journal of Inherited Metabolic Disease

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

56

Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease

Sanders, Laurie H., McCoy, Jennifer, Hu, Xiaoping, Mastroberardino, Pier G., Dickinson, Bryan C., Chang, Christopher J., Chu, Charleen T., Van Houten, Bennett, Greenamyre, J.T.

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

57

SUMOylation-Dependent LRH-1/PROX1 Interaction Promotes Atherosclerosis by Decreasing Hepatic Reverse Cholesterol Transport

Stein, Sokrates, Oosterveer, Maaike H., Mataki, Chikage, Xu, Pan, Lemos, Vera, Havinga, Rick, Dittner, Claudia, Ryu, Dongryeol, Menzies, Keir J., Wang, Xu, Perino, Alessia, Houten, Sander M., Melchior

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

58

High-protein diets prevent steatosis and induce hepatic accumulation of monomethyl branched-chain fatty acids

Garcia Caraballo, Sonia C., Comhair, Tine M., Houten, Sander M., Dejong, Cornelis H.C., Lamers, Wouter H., Koehler, S. Eleonore

Journal:

The Journal of Nutritional Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

59

Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice

Baptissart, Marine, Vega, Aurélie, Martinot, Emmanuelle, Pommier, Aurélien J., Houten, Sander M., Marceau, Geoffroy, Haze, Angélique de, Baron, Silvère, Schoonjans, Kristina, Lobaccaro, Jean-Marc A.,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

60

Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice

Ciapaite, Jolita, van den Berg, Sjoerd A., Houten, Sander M., Nicolay, Klaas, Willems van Dijk, Ko, Jeneson, Jeroen A.

Journal:

The Journal of Nutritional Biochemistry

Year:

2015

Language:

english

File:

PDF, 639 KB

english, 2015

61

The metabolic footprint of aging in mice

Houtkooper, Riekelt H., Argmann, Carmen, Houten, Sander M., Cantó, Carles, Jeninga, Ellen H., Andreux, Pénélope A., Thomas, Charles, Doenlen, Raphaël, Schoonjans, Kristina, Auwerx, Johan

Journal:

Scientific Reports

Year:

2011

Language:

english

File:

PDF, 2.53 MB

english, 2011

62

PS6 - 1. γ-Butyrobetaine impairs glucose tolerance in mice on a high carbohydrate diet

Schooneman, Marieke G., Vaz, Frederic M., Hollak, Carla E., Soeters, Maarten R., Houten, Sander M.

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2013

Language:

english

File:

PDF, 231 KB

english, 2013

63

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

Watanabe, Mitsuhiro, Horai, Yasushi, Houten, Sander M., Morimoto, Kohkichi, Sugizaki, Taichi, Arita, Eri, Mataki, Chikage, Sato, Hiroyuki, Tanigawara, Yusuke, Schoonjans, Kristina, Itoh, Hiroshi, Auwe

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011

64

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

Watanabe, Mitsuhiro, Houten, Sander M., Wang, Li, Moschetta, Antonio, Mangelsdorf, David J., Heyman, Richard A., Moore, David D., Auwerx, Johan

Journal:

Journal of Clinical Investigation

Year:

2004

Language:

english

File:

PDF, 641 KB

english, 2004

65

Novel, Compound Heterozygous, Single-Nucleotide Variants in MARS2 Associated with Developmental Delay, Poor Growth, and Sensorineural Hearing Loss

Webb, Bryn D., Wheeler, Patricia G., Hagen, Jacob J., Cohen, Ninette, Linderman, Michael D., Diaz, George A., Naidich, Thomas P., Rodenburg, Richard J., Houten, Sander M., Schadt, Eric E.

Journal:

Year:

2015

Language:

english

File:

PDF, 493 KB

english, 2015

66

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

Fernandez-Marcos, Pablo J., Jeninga, Ellen H., Canto, Carles, Harach, Taoufiq, de Boer, Vincent C. J., Andreux, Penelope, Moullan, Norman, Pirinen, Eija, Yamamoto, Hiroyasu, Houten, Sander M., Schoonj

Journal:

Scientific Reports

Year:

2012

Language:

english

File:

PDF, 609 KB

english, 2012

67

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

van Eunen, Karen, Simons, Sereh M. J., Gerding, Albert, Bleeker, Aycha, den Besten, Gijs, Touw, Catharina M. L., Houten, Sander M., Groen, Bert K., Krab, Klaas, Reijngoud, Dirk-Jan, Bakker, Barbara M.

Journal:

PLoS Computational Biology

Year:

2013

Language:

english

File:

PDF, 588 KB

english, 2013

68

Fatty acid oxidation flux predicts the clinical severity of VLCAD deficiency

Diekman, Eugene F., Ferdinandusse, Sacha, van der Pol, Ludo, Waterham, Hans R., Ruiter, Jos P. N., Ijlst, Lodewijk, Wanders, Ronald J., Houten, Sander M., Wijburg, Frits A., Blank, A. Christiaan, Asse

Journal:

Genetics in Medicine

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

69

Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of Body Weight and Thermogenesis

Schulz, Nadja, Himmelbauer, Heinz, Rath, Michaela, van Weeghel, Michel, Houten, Sander, Kulik, Wim, Suhre, Karsten, Scherneck, Stephan, Vogel, Heike, Kluge, Reinhart, Wiedmer, Petra, Joost, Hans-Georg

Journal:

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

70

Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo

Wessels, Bart, van den Broek, Nicole M. A., Ciapaite, Jolita, Houten, Sander M., Wanders, Ronald J. A., Nicolay, Klaas, Prompers, Jeanine J.

Journal:

AJP Endocrinology and Metabolism

Year:

2015

Language:

english

File:

PDF, 895 KB

english, 2015

71

The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

Houten, Sander M., Violante, Sara, Ventura, Fatima V., Wanders, Ronald J.A.

Journal:

Annual Review of Physiology

Year:

2016

File:

PDF, 891 KB

2016

72

The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

Houten, Sander M., Violante, Sara, Ventura, Fatima V., Wanders, Ronald J.A.

Journal:

Annual Review of Physiology

Year:

2016

Language:

english

File:

PDF, 891 KB

english, 2016

73

Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism

Schooneman, Marieke G., Ten Have, Gabriella A. M., van Vlies, Naomi, Houten, Sander M., Deutz, Nicolaas E. P., Soeters, Maarten R.

Journal:

AJP Endocrinology and Metabolism

Year:

2015

Language:

english

File:

PDF, 242 KB

english, 2015

74

In Vivo Imaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile Acid Signaling Tissue

Houten, Sander M., Volle, David H., Cummins, Carolyn L., Mangelsdorf, David J., Auwerx, Johan

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 796 KB

english, 2007

75

A Next Generation Multiscale View of Inborn Errors of Metabolism

Argmann, Carmen A., Houten, Sander M., Zhu, Jun, Schadt, Eric E.

Journal:

Cell Metabolism

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

76

The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice

Schooneman, Marieke G., Houtkooper, Riekelt H., Hollak, Carla E.M., Wanders, Ronald J.A., Vaz, Frédéric M., Soeters, Maarten R., Houten, Sander M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

77

Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication

Long, Quan, Argmann, Carmen, Houten, Sander M., Huang, Tao, Peng, Siwu, Zhao, Yong, Tu, Zhidong, Zhu, Jun

Journal:

Genome Medicine

Year:

2016

Language:

english

File:

PDF, 3.00 MB

english, 2016

78

A PPARγ-Bnip3 axis couples adipose mitochondrial fusion-fission balance to systemic insulin sensitivity

Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johanne

Journal:

Year:

2016

Language:

english

File:

PDF, 3.01 MB

english, 2016

79

Effect of Statins on the Viability of Macrophages and Smooth Muscle Cells

Croons, Valerie, De Meyer, Inge, Houten, Sander M, Martinet, Wim, Bult, Hidde, Herman, Arnold G, De Meyer, Guido R Y

Journal:

Journal of Cardiovascular Pharmacology

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

80

In vivo proton T 1 relaxation times of mouse myocardial metabolites at 9.4 T

Bakermans, Adrianus J., Abdurrachim, Desiree, Geraedts, Tom R., Houten, Sander M., Nicolay, Klaas, Prompers, Jeanine J.

Journal:

Magnetic Resonance in Medicine

Year:

2015

Language:

english

File:

PDF, 348 KB

english, 2015

81

In vivo mouse myocardial 31 P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations

Bakermans, Adrianus J., Abdurrachim, Desiree, van Nierop, Bastiaan J., Koeman, Anneke, van der Kroon, Inge, Baartscheer, Antonius, Schumacher, Cees A., Strijkers, Gustav J., Houten, Sander M., Zuurbie

Journal:

NMR in Biomedicine

Year:

2015

Language:

english

File:

PDF, 717 KB

english, 2015

82

Assessment of plasma acylcarnitines before and after weight loss in obese subjects

Schooneman, Marieke G., Napolitano, Antonella, Houten, Sander M., Ambler, Graeme K., Murgatroyd, Peter R., Miller, Sam R., Hollak, Carla E.M., Tan, Chong Y., Virtue, Samuel, Vidal-Puig, Antonio, Nunez

Journal:

Archives of Biochemistry and Biophysics

Year:

2016

Language:

english

File:

PDF, 633 KB

english, 2016

83

Muscle acylcarnitines during short-term fasting in lean healthy men

Soeters, Maarten R., Sauerwein, Hans P., Duran, Marinus, Wanders, Ronald J., Ackermans, Mariëtte T., Fliers, Eric, Houten, Sander M., Serlie, Mireille J.

Journal:

Clinical Science

Year:

2009

Language:

english

File:

PDF, 202 KB

english, 2009

84

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2016

Language:

english

File:

PDF, 200 KB

english, 2016

85

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2016

Language:

english

File:

PDF, 202 KB

english, 2016

86

A host-protein based assay to differentiate between bacterial and viral infections in preschool children (OPPORTUNITY): a double-blind, multicentre, validation study

van Houten, Chantal B, de Groot, Joris A H, Klein, Adi, Srugo, Isaac, Chistyakov, Irena, de Waal, Wouter, Meijssen, Clemens B, Avis, Wim, Wolfs, Tom F W, Shachor-Meyouhas, Yael, Stein, Michal, Sanders

Journal:

The Lancet Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 297 KB

english, 2017

87

Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome

Webb, Bryn D., Metikala, Sanjeeva, Wheeler, Patricia G., Sherpa, Mingma D., Houten, Sander M., Horb, Marko E., Schadt, Eric E.

Journal:

Year:

2017

Language:

english

File:

PDF, 438 KB

english, 2017

88

Meningococcal carriage in Dutch adolescents and young adults; a cross-sectional and longitudinal cohort study

van Ravenhorst, M.B., Bijlsma, M.W., van Houten, M.A., Struben, V.M.D., Anderson, A.S., Eiden, J., Hao, L., Jansen, K.U., Jones, H., Kitchin, N., Pedneault, L., Sanders, E.A.M., van der Ende, A.

Journal:

Clinical Microbiology and Infection

Year:

2017

Language:

english

File:

PDF, 817 KB

english, 2017

89

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2017

Language:

english

File:

PDF, 189 KB

english, 2017

90

Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart

Nederlof, Rianne, Denis, Simone, Lauzier, Benjamin, Rosiers, Christine Des, Laakso, Markku, Hagen, Jacob, Argmann, Carmen, Wanders, Ronald, Houtkooper, Riekelt H., Hollmann, Markus W., Houten, Sander

Journal:

Year:

2017

Language:

english

File:

PDF, 420 KB

english, 2017

91

News and views

Sander M. Houten

Journal:

Journal of Inherited Metabolic Disease

Year:

2017

Language:

english

File:

PDF, 184 KB

english, 2017

92

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2017

Language:

english

File:

PDF, 264 KB

english, 2017

93

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Argmann, Carmen A., Violante, Sara, Dodatko, Tetyana, Amaro, Mariana P., Hagen, Jacob, Gillespie, Virginia L., Buettner, Christoph, Schadt, Eric E., Houten, Sander M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

94

Deficiency of the Mitochondrial NAD Kinase Causes Stress-induced hepatic steatosis in mice

Zhang, Kezhong, Kim, Hyunbae, Fu, Zhiyao, Qiu, Yining, Yang, Zhao, Wang, Jiemei, Zhang, Deqiang, Tong, Xin, Yin, Lei, Li, Jing, Wu, Jianmei, Qi, Nathan R., Houten, Sander M., Zhang, Ren

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 6.84 MB

english, 2017

95

[WORLD SCIENTIFIC Proceedings of the Pacific Symposium - Kohala Coast, Hawaii, USA (3 – 7 January 2018)] Biocomputing 2018 - Characterization of drug-induced splicing complexity in prostate cancer cell line using long read technology

Chen, Xintong, Houten, Sander, Allette, Kimaada, Sebra, Robert P., Stolovitzky, Gustavo, Losic, Bojan

Language:

english

File:

PDF, 1.92 MB

english

96

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2017

Language:

english

File:

PDF, 276 KB

english, 2017

97

News and views

Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2018

Language:

english

File:

PDF, 68 KB

english, 2018

98

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

Watanabe, Mitsuhiro, Morimoto, Kohkichi, Houten, Sander M., Kaneko-Iwasaki, Nao, Sugizaki, Taichi, Horai, Yasushi, Mataki, Chikage, Sato, Hiroyuki, Murahashi, Karin, Arita, Eri, Schoonjans, Kristina,

Journal:

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

99

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen,

Journal:

Journal of Diabetes Research

Year:

2015

Language:

english

File:

PDF, 5.18 MB

english, 2015

100

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

Sahu, A., Mamiya, H., Shinde, S. N., Cheikhi, A., Winter, L. L., Vo, N. V., Stolz, D., Roginskaya, V., Tang, W. Y., St. Croix, C., Sanders, L. H., Franti, M., Van Houten, B., Rando, T. A., Barchowsky,

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 4.83 MB

english, 2018

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