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1

Pharmacogenomics Knowledge for Personalized Medicine

Whirl-Carrillo, M, McDonagh, E M, Hebert, J M, Gong, L, Sangkuhl, K, Thorn, C F, Altman, R B, Klein, T E

Journal:

Clinical Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 963 KB

english, 2012

2

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy

Scott, S A, Sangkuhl, K, Gardner, E E, Stein, C M, Hulot, J-S, Johnson, J A, Roden, D M, Klein, T E, Shuldiner, A R

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 137 KB

english, 2011

3

Selective serotonin reuptake inhibitors pathway

Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2009

Language:

english

File:

PDF, 124 KB

english, 2009

4

Clopidogrel pathway

Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2010

Language:

english

File:

PDF, 126 KB

english, 2010

5

Cytochrome P450 2C9-CYP2C9

Van Booven, Derek, Marsh, Sharon, McLeod, Howard, Carrillo, Michelle Whirl, Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

6

Nephrogenic diabetes insipidus caused by mutation of Tyr205: A key residue of V2 vasopressin receptor function

Katrin Sangkuhl, Holger Römpler, Wibke Busch, Beate Karges, Torsten Schöneberg

Journal:

Year:

2005

Language:

english

File:

PDF, 679 KB

english, 2005

7

702: Comprehensive maternal-fetal pharmacogenomics – a novel pharmacogenomic thumbprint

Yair Blumenfeld, Christina Fan, Katrin Sangkuhl, Russ Altman, Yasser El-Sayed, Stephen Quake

Journal:

American Journal of Obstetrics and Gynecology

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

8

Mutant G-protein-coupled receptors as a cause of human diseases

Torsten Schöneberg, Angela Schulz, Heike Biebermann, Thomas Hermsdorf, Holger Römpler, Katrin Sangkuhl

Journal:

Pharmacology & Therapeutics

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

9

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants

Hicks, J K, Swen, J J, Thorn, C F, Sangkuhl, K, Kharasch, E D, Ellingrod, V L, Skaar, T C, Müller, D J, Gaedigk, A, Stingl, J C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 413 KB

english, 2013

10

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

Scott, S A, Sangkuhl, K, Stein, C M, Hulot, J-S, Mega, J L, Roden, D M, Klein, T E, Sabatine, M S, Johnson, J A, Shuldiner, A R

Journal:

Clinical Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 702 KB

english, 2013

11

PharmGKB: Understanding the Effects of Individual Genetic Variants

Sangkuhl, Katrin, Berlin, Dorit S., Altman, Russ B., Klein, Teri E.

Journal:

Drug Metabolism Reviews

Year:

2008

Language:

english

File:

PDF, 1.68 MB

english, 2008

12

V2 vasopressin receptor deficiency causes changes in expression and function of renal and hypothalamic components involved in electrolyte and water homeostasis

Schliebe, N., Strotmann, R., Busse, K., Mitschke, D., Biebermann, H., Schomburg, L., Kohrle, J., Bar, J., Rompler, H., Wess, J., Schoneberg, T., Sangkuhl, K.

Journal:

AJP Renal Physiology

Year:

2008

Language:

english

File:

PDF, 365 KB

english, 2008

13

Altered Immune Response in Mice Deficient for the G Protein-coupled Receptor GPR34

Liebscher, I., Muller, U., Teupser, D., Engemaier, E., Engel, K. M. Y., Ritscher, L., Thor, D., Sangkuhl, K., Ricken, A., Wurm, A., Piehler, D., Schmutzler, S., Fuhrmann, H., Albert, F. W., Reichenbac

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.37 MB

english, 2011

14

Structural Requirements for Mutational Lutropin/Choriogonadotropin Receptor Activation

Sangkuhl, K., Schulz, A., Schultz, G., Schoneberg, T.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 290 KB

english, 2002

15

Identification of Receptors and Signaling Pathways for Orphan Bone Morphogenetic Protein/Growth Differentiation Factor Ligands Based on Genomic Analyses

Mazerbourg, S., Sangkuhl, K., Luo, C.-W., Sudo, S., Klein, C., Hsueh, A. J. W.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

16

PharmGKB summary

Lamba, Vishal, Sangkuhl, Katrin, Sanghavi, Kinjal, Fish, Alyssa, Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2014

Language:

english

File:

PDF, 434 KB

english, 2014

17

PharmGKB summary

Sangkuhl, Katrin, Stingl, Julia C., Turpeinen, Miia, Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

18

PharmGKB summary

Alvarellos, Maria L., Lamba, Jatinder, Sangkuhl, Katrin, Thorn, Caroline F., Wang, Liewei, Klein, Daniel J., Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2014

Language:

english

File:

PDF, 630 KB

english, 2014

19

PharmGKB summary

Alvarellos, Maria L., Sangkuhl, Katrin, Daneshjou, Roxana, Whirl-Carrillo, Michelle, Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2015

Language:

english

File:

PDF, 384 KB

english, 2015

20

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

Biernacka, J M, Sangkuhl, K, Jenkins, G, Whaley, R M, Barman, P, Batzler, A, Altman, R B, Arolt, V, Brockmöller, J, Chen, C H, Domschke, K, Hall-Flavin, D K, Hong, C J, Illi, A, Ji, Y, Kampman, O, Kin

Journal:

Translational Psychiatry

Year:

2015

Language:

english

File:

PDF, 1.71 MB

english, 2015

21

Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo

Journal:

Human Molecular Genetics

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

22

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

Hicks, JK, Bishop, JR, Sangkuhl, K, Müller, DJ, Ji, Y, Leckband, SG, Leeder, JS, Graham, RL, Chiulli, DL, LLerena, A, Skaar, TC, Scott, SA, Stingl, JC, Klein, TE, Caudle, KE, Gaedigk, A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 697 KB

english, 2015

23

Aminoglycoside Pretreatment Partially Restores the Function of Truncated V 2 Vasopressin Receptors Found in Patients with Nephrogenic Diabetes Insipidus

Schulz, Angela, Sangkuhl, Katrin, Lennert, Thomas, Wigger, Marianne, Price, David Anthony, Nuuja, Anja, Grüters, Annette, Schultz, Günter, Schöneberg, Torsten

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2002

Language:

english

File:

PDF, 711 KB

english, 2002

24

PharmGKB summary

Mazaleuskaya, Liudmila L., Sangkuhl, Katrin, Thorn, Caroline F., FitzGerald, Garret A., Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2015

Language:

english

File:

PDF, 348 KB

english, 2015

25

Platelet aggregation pathway

Sangkuhl, Katrin, Shuldiner, Alan R., Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 211 KB

english, 2011

26

Cytochrome P450 2D6

Owen, Ryan P., Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

27

PharmGKB summary

Mi, Huaiyu, Thomas, Paul D., Ring, Huijun Z., Jiang, Ruhong, Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 133 KB

english, 2011

28

Using ODIN for a PharmGKB revalidation experiment

Rinaldi, F., Clematide, S., Garten, Y., Whirl-Carrillo, M., Gong, L., Hebert, J. M., Sangkuhl, K., Thorn, C. F., Klein, T. E., Altman, R. B.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

29

PharmGKB summary

Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 155 KB

english, 2011

30

PharmGKB summary

Berlin, Dorit S., Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

31

PharmGKB summary

Ghodke, Yogita, Anderson, Peter L., Sangkuhl, Katrin, Lamba, Jatinder, Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2012

Language:

english

File:

PDF, 279 KB

english, 2012

32

Prediction of CYP2D6 phenotype from genotype across world populations

Gaedigk, Andrea, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Klein, Teri, Leeder, J. Steven

Journal:

Genetics in Medicine

Year:

2016

Language:

english

File:

PDF, 1.25 MB

english, 2016

33

PharmGKB

Medina, Marisa Wong, Sangkuhl, Katrin, Klein, Teri E., Altman, Russ B.

Journal:

Pharmacogenetics and Genomics

Year:

2011

Language:

english

File:

PDF, 88 KB

english, 2011

34

PharmGKB summary

Scott, Stuart A., Sangkuhl, Katrin, Shuldiner, Alan R., Hulot, Jean-Sébastien, Thorn, Caroline F., Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

35

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

Biernacka, J M, Sangkuhl, K, Jenkins, G, Whaley, R M, Barman, P, Batzler, A, Altman, R B, Arolt, V, Brockmöller, J, Chen, C H, Domschke, K, Hall-Flavin, D K, Hong, C J, Illi, A, Ji, Y, Kampman, O, Kin

Journal:

Translational Psychiatry

Year:

2016

Language:

english

File:

PDF, 818 KB

english, 2016

36

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

Hicks, JK, Sangkuhl, K, Swen, JJ, Ellingrod, VL, Müller, DJ, Shimoda, K, Bishop, JR, Kharasch, ED, Skaar, TC, Gaedigk, A, Dunnenberger, HM, Klein, TE, Caudle, KE, Stingl, JC

Journal:

Clinical Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 885 KB

english, 2017

37

Molecular basis and clinical features of nephrogenic diabetes insipidus

Schulz, Angela, Römpler, Holger, Mitschke, Doreen, Thor, Doreen, Schliebe, Nicole, Hermsdorf, Thomas, Strotmann, Rainer, Sangkuhl, Katrin, Schöneberg, Torsten

Journal:

Expert Review of Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 408 KB

english, 2006

38

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

Goetz, Matthew P., Sangkuhl, Katrin, Guchelaar, Henk-Jan, Schwab, Matthias, Province, Michael, Whirl-Carrillo, Michelle, Symmans, W. Fraser, McLeod, Howard L., Ratain, Mark J., Zembutsu, Hitoshi, Gaed

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 311 KB

english, 2018

39

Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder

Amare, Azmeraw T., Schubert, Klaus Oliver, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Sangkuhl, Katrin, Jenkins, Gregory, Whaley, Ryan M., Barman, Poulami, Batzler, Anthony, Altman, Russ B., Arolt, Volker,

Journal:

Frontiers in Psychiatry

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

40

An Inequitable, Complex and Inefficient Taxation System

Sangkuhl, Elfriede

Journal:

Alternative Law Journal

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

41

Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

Caudle, Kelly, Klein, Teri, Hoffman, James, Muller, Daniel, Whirl-Carrillo, Michelle, Gong, Li, McDonagh, Ellen, Sangkuhl, Katrin, Thorn, Caroline, Schwab, Matthias, Agundez, Jose, Freimuth, Robert, H

Journal:

Current Drug Metabolism

Year:

2014

Language:

english

File:

PDF, 167 KB

english, 2014

42

The Case for Pharmacogenetics-Guided Prescribing of Codeine in Children

Gammal, Roseann S., Caudle, Kelly E., Quinn, Charles T., Wang, Winfred C., Gaedigk, Andrea, Prows, Cynthia A., Haidar, Cyrine E., Taylor, Annette K., Klein, Teri E., Sangkuhl, Katrin, Hankins, Jane S.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 129 KB

english, 2018

43

Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for the use of potent volatile anesthetic agents and succinylcholine in the context of RYR1 or CACNA1S genotypes

Gonsalves, Stephen G., Dirksen, Robert T., Sangkuhl, Katrin, Pulk, Rebecca, Alvarellos, Maria, Vo, Teresa, Hikino, Keiko, Roden, Dan, Klein, Teri, Mark Poler, S., Patel, Sephalie, Caudle, Kelly E., Go

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 573 KB

english, 2018

44

The Evolution of PharmVar

Gaedigk, Andrea, Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Twist, Greyson P., Klein, Teri E., Miller, Neil A.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 327 KB

english, 2018

45

The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression

Amare, Azmeraw T., Schubert, Klaus Oliver, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Sangkuhl, Katrin, Jenkins, Gregory, Whaley, Ryan M., Barman, Poulami, Batzler, Anthony, Altman, Russ B., Arolt, Volker,

Journal:

Journal of Neural Transmission

Year:

2019

Language:

english

File:

PDF, 2.74 MB

english, 2019

46

Are Randomized Controlled Trials Necessary to Establish the Value of Implementing Pharmacogenomics in the Clinic?

Huddart, Rachel, Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Klein, Teri E.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2019

Language:

english

File:

PDF, 123 KB

english, 2019

47

Pharmacogenomics Clinical Annotation Tool (Pharm CAT )

Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Whaley, Ryan M., Woon, Mark, Lavertu, Adam, Altman, Russ B., Carter, Lester, Verma, Anurag, Ritchie, Marylyn D., Klein, Teri E.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2019

Language:

english

File:

PDF, 441 KB

english, 2019

48

Standardizing CYP 2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group

Caudle, Kelly E., Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Swen, Jesse J., Haidar, Cyrine E., Klein, Teri E., Gammal, Roseann S., Relling, Mary V., Scott, Stuart A., Hertz, Daniel L., Guchelaar, He

Journal:

Clinical and Translational Science

Year:

2019

Language:

english

File:

PDF, 508 KB

english, 2019

49

A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy

Hicks, J. Kevin, Bishop, Jeffrey R., Gammal, Roseann S., Sangkuhl, Katrin, Bousman, Chad A., Leeder, J. Steven, Llerena, Adrián, Mueller, Daniel J., Ramsey, Laura B., Scott, Stuart A., Skaar, Todd C.,

Journal:

Clinical Pharmacology & Therapeutics

Year:

2019

Language:

english

File:

PDF, 136 KB

english, 2019

50

PharmGKB summary

Stevens, Tyler, Sangkuhl, Katrin, Brown, Jacob T., Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2019

File:

PDF, 457 KB

2019