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1

Desmopressin in moderate hemophilia A patients: a treatment worth considering

Loomans, Janneke I., Kruip, Marieke J.H.A., Carcao, Manuel, Jackson, Shannon, van Velzen, Alice S., Peters, Marjolein, Santagostino, Elena, Platokouki, Helen, Beckers, Erik, Voorberg, Jan, van der Bom

Journal:

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

2

The changing face of immune tolerance induction in haemophilia A with the advent of emicizumab

Carcao, Manuel, Escuriola‐Ettingshausen, Carmen, Santagostino, Elena, Oldenburg, Johannes, Liesner, Ri, Nolan, Beatrice, Bátorová, Angelika, Haya, Saturnino, Young, Guy

Journal:

Year:

2019

Language:

english

File:

PDF, 544 KB

english, 2019

3

Pharmacokinetics of a new human plasma‐derived double virus inactivated and nanofiltered factor IX concentrate in previously treated severe or moderately severe haemophilia B patients

Castaman, Giancarlo, Borchiellini, Alessandra, Santagostino, Elena, Tagariello, Giuseppe, Serban, Margit, Uscatescu, Marusia, Truica, Cristina, Farrugia, Albert, Morfini, Massimo

Journal:

Year:

2019

Language:

english

File:

PDF, 345 KB

english, 2019

4

Pharmacokinetics of a new human plasma‐derived double virus inactivated and nanofiltered factor IX concentrate in previously treated severe or moderately severe haemophilia B patients

Castaman, Giancarlo, Borchiellini, Alessandra, Santagostino, Elena, Tagariello, Giuseppe, Serban, Margit, Uscatescu, Marusia, Truica, Cristina, Farrugia, Albert, Morfini, Massimo

Journal:

Year:

2019

File:

PDF, 345 KB

2019

5

Recombinant factor VIII Fc fusion protein for the treatment of severe haemophilia A: Final results from the ASPIRE extension study

Nolan, Beatrice, Mahlangu, Johnny, Pabinger, Ingrid, Young, Guy, Konkle, Barbara A., Barnes, Chris, Nogami, Keiji, Santagostino, Elena, Pasi, K. John, Khoo, Liane, Winding, Bent, Yuan, Huixing, Fruebi

Journal:

Year:

2020

File:

PDF, 522 KB

2020

6

X Chromosome inactivation: a modifier of factor VIII and IX plasma levels and bleeding phenotype in Haemophilia carriers

Garagiola, Isabella, Mortarino, Mimosa, Siboni, Simona Maria, Boscarino, Marco, Mancuso, Maria Elisa, Biganzoli, Marina, Santagostino, Elena, Peyvandi, Flora

Journal:

European Journal of Human Genetics

Year:

2020

File:

PDF, 589 KB

2020

7

Accelerated schedule of hepatitis B vaccination in patients with hemophilia

Elena Santagostino, Dr. Pier Mannuccio Mannucci, Alessandro Gringeri, Maria Grazia Rumi, Daniela Rafanelli, Angiola Rocino, Mario Schiavoni, Antonio Chistolini, Eros Di Bona, Gaetano Muleo

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 487 KB

english, 1993

8

Gene mutations and three-dimensional structural analysis in 13 families with severe factor X deficiency

Flora Peyvandi, Marzia Menegatti, Elena Santagostino, Sepideh Akhavan, James Uprichard, David J. Perry, Stephen J. Perkins, Pier M. Mannucci

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 318 KB

english, 2002

9

A prospective study of recombinant activated factor VII administered by continuous infusion to inhibitor patients undergoing elective major orthopaedic surgery: a pharmacokinetic and efficacy evaluation

Christopher A. Ludlam, Mark P. Smith, Massimo Morfini, Alessandro Gringeri, Elena Santagostino, Geoffrey F. Savidge

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 74 KB

english, 2003

10

Long-term safety and feasibility of arteriovenous fistulae as vascular accesses in children with haemophilia: a prospective study

Elena Santagostino, Alessandro Gringeri, Luisa Berardinelli, Claudio Beretta, Myrvet Muça-Perja, Pier Mannuccio Mannucci

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 69 KB

english, 2003

11

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects the actin cytoskeleton and calcium level of Swiss 3T3 mouse fibroblasts

Chiara Urani, Elena Brambilla, Angela Santagostino, Marina Camatini

Journal:

Year:

1994

Language:

english

File:

PDF, 1.90 MB

english, 1994

12

A novel two base pair deletion in the factor V gene associated with severe factor V deficiency

Maria Claudia Montefusco, Stefano Duga, Rosanna Asselta, Elena Santagostino, Giacomo Mancuso, Massimo Malcovati, Pier Mannuccio Mannucci, Maria Luisa Tenchini

Journal:

British Journal of Haematology

Year:

2000

Language:

english

File:

PDF, 167 KB

english, 2000

13

Efficacy and inhibitor development in previously treated patients with haemophilia A switched to a B domain-deleted recombinant factor VIII

Alessandro Gringeri, Annarita Tagliaferri, Giuseppe Tagariello, Massimo Morfini, Elena Santagostino, Piermannuccio Mannucci, the ReFacto–AICE Study Group

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

14

Environmental risk factors for inhibitor development in children with haemophilia A: a case–control study

Elena Santagostino, Maria Elisa Mancuso, Angiola Rocino, Giacomo Mancuso, Maria Gabriella Mazzucconi, Annarita Tagliaferri, Maria Messina, Pier Mannuccio Mannucci

Journal:

British Journal of Haematology

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

15

Protective effect of prophylaxis on inhibitor development in children with haemophilia A: more convincing studies are required. Response to Calvez and Laurian

Elena Santagostino, Pier Mannuccio Mannucci

Journal:

British Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

16

Feasibility of prophylaxis and immune tolerance induction regimens in haemophilic children using fully implantable central venous catheters

Maria Elisa Mancuso, Pier Mannuccio Mannucci, Angelo Sartori, Andrea Agliardi, Elena Santagostino

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 138 KB

english, 2008

17

Circulating endothelial cells (CECs) and progenitors (CEPs) in severe haemophiliacs with different clinical phenotype

Eugenia Biguzzi, Patrizia Mancuso, Franca Franchi, Angelica Calleri, Maria Elisa Mancuso, Elena Santagostino, Paolo Bucciarelli, Francesco Bertolini, Pier M. Mannucci

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 79 KB

english, 2009

18

Factors influencing the long-term outcome of primary total knee replacement in haemophiliacs: a review of 116 procedures at a single institution

Luigi P. Solimeno, Maria E. Mancuso, Gianluigi Pasta, Elena Santagostino, Samantha Perfetto, Pier Mannuccio Mannucci

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

19

Optimizing management of immune tolerance induction in patients with severe haemophilia A and inhibitors: towards evidence-based approaches

Antonio Coppola, Matteo N. D. Di Minno, Elena Santagostino

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 412 KB

english, 2010

20

The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats

Simonet, Thomas, Zaragosi, Laure-Emmanuelle, Philippe, Claude, Lebrigand, Kevin, Schouteden, Clémentine, Augereau, Adeline, Bauwens, Serge, Ye, Jing, Santagostino, Marco, Giulotto, Elena

Journal:

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

21

Defective nef Alleles in a Cohort of Hemophiliacs with Progressing and Nonprogressing HIV-1 Infection

Andrea Brambilla, Lucia Turchetto, Alessandra Gatti, Chiara Bovolenta, Fabrizio Veglia, Elena Santagostino, Alessandro Gringeri, Massimo Clementi, Guido Poli, Patrizia Bagnarelli, Elisa Vicenzi

Journal:

Year:

1999

Language:

english

File:

PDF, 406 KB

english, 1999

22

Intramuscular anti-D immunoglobulins for home treatment of chronic immune thrombocytopenic purpura

Alessandro Gringeri, Marco Cattaneo, Elena Santagostino, Pier Mannuccio Mannucci

Journal:

British Journal of Haematology

Year:

1992

Language:

english

File:

PDF, 412 KB

english, 1992

23

Difficult clinical challenges in haemophilia: international experiential perspectives

ANGELA L. FORSYTH, PAUL GIANGRANDE, CHARLES R. M. HAY, GILI KENET, CRAIG M. KESSLER, PAUL N. KNÖBL, ADOLFO LLINÁS, ELENA SANTAGOSTINO, GUY YOUNG

Journal:

Year:

2012

Language:

english

File:

PDF, 80 KB

english, 2012

24

Long-term treatment with zidovudine in patients with human immunodeficiency virus (HIV)-associated thrombocytopenia: Modes of response and correlation with markers of HIV replication

Paola Cinque, Guiseppe Landonio, Adriano Lazzarin, Anna Maria Nosari, Alessandro Ruggieri, Massimo Coen, Paolo Meraviglia, Alessandro Gringeri, Luciana Gallo, Tiziana Quirino, Elena Santagostino, Mari

Journal:

European Journal of Haematology

Year:

1993

Language:

english

File:

PDF, 401 KB

english, 1993

25

Hepatitis C virus (HCV) coinfection in a cohort of HIV positive long-term non-progressors: Possible protective effect of infecting HCV genotype on HIV disease progression

Giulia Morsica, Sabrina Bagaglio, Silvia Ghezzi, Chiara Lodrini, Elisa Vicenzi, Elena Santagostino, Alessandro Gringeri, Marco Cusini, Guido Carminati, Giampaolo Bianchi, Laura Galli, Adriano Lazzarin

Journal:

Journal of Clinical Virology

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

26

Melanocortin peptides inhibit production of proinflammatory cytokines in blood of HIV-infected patients

Anna Catania, Letizia Garofalo, Mariagrazia Cutuli, Alessandro Gringeri, Elena Santagostino, James M. Lipton

Journal:

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

27

Mean platelet volume and the extent of coronary artery disease: Results from a large prospective study

Giuseppe De Luca, Matteo Santagostino, Gioel Gabrio Secco, Ettore Cassetti, Livio Giuliani, Elena Franchi, Lorenzo Coppo, Sergio Iorio, Luca Venegoni, Elisa Rondano, Gabriele Dell’Era, Claudia Rizzo,

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 506 KB

english, 2009

28

PRO-PACT: Retrospective observational study on the prophylactic use of recombinant factor VIIa in hemophilia patients with inhibitors

Young, Guy, Auerswald, Guenter, Jimenez-Yuste, Victor, Lambert, Thierry, Morfini, Massimo, Santagostino, Elena, Blanchette, Victor

Journal:

Thrombosis Research

Year:

2012

Language:

english

File:

PDF, 178 KB

english, 2012

29

PROLONG-9FP clinical development program – phase I results of recombinant fusion protein linking coagulation factor IX with recombinant albumin (rIX-FP)

Santagostino, Elena

Journal:

Thrombosis Research

Year:

2013

Language:

english

File:

PDF, 430 KB

english, 2013

30

C-C Chemokines, Pivotal in Protection against HIV Type 1 Infection

Daniel Zagury, Abderrahim Lachgar, Vida Chams, Lat S. Fall, Jacky Bernard, Jean-Francois Zagury, Bernard Bizzini, Alessandro Gringeri, Elena Santagostino, Jay Rappaport, Michael Feldman, Stephen J. O'

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.31 MB

english, 1998

31

Interferon α and Tat Involvement in the Immunosuppression of Uninfected T Cells and C-C Chemokine Decline in AIDS

Daniel Zagury, Abderrahim Lachgar, Vida Chams, Lat S. Fall, Jacky Bernard, Jean-Francois Zagury, Bernard Bizzini, Alessandro Gringeri, Elena Santagostino, Jay Rappaport, Michael Feldman, Arsene Burny

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.48 MB

english, 1998

32

Switching treatments in haemophilia: is there a risk of inhibitor development?

Santagostino, Elena, Auerswald, Günter, Benson, Gary, Dolan, Gerry, Jiménez-Yuste, Victor, Lambert, Thierry, Ljung, Rolf, Morfini, Massimo, Remor, Eduardo, Zupančić Šalek, Silva

Journal:

European Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 178 KB

english, 2015

33

State of Care for Hemophilia in Pediatric Patients

Dr Elena Santagostino,Alessandro Gringeri,Pier M. Mannucci

Journal:

Paediatric Drugs

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

34

Frequency of a Mutated CCR-5 Allele (Delta32) among Italian Healthy Donors and Individuals at Risk of Parenteral HIV Infection

Zamarchi, Rita, Indraccolo, Stefano, Minuzzo, Sonia, Coppola, Vincenzo, Gringeri, Alessandro, Santagostino, Elena, Vicenzi, Elisa, Silvestro, Giustina De, Biagiotti, Roberta, Baldassarre, Clara, Chiec

Journal:

AIDS Research and Human Retroviruses

Year:

1999

Language:

english

File:

PDF, 135 KB

english, 1999

35

Clot lysis phenotype and response to recombinant factor VIIa in plasma of haemophilia A inhibitor patients

Bakhtiari, Kamran, Kamphuisen, Pieter W., Mancuso, Maria E., Hamulyak, Karly, Schutgens, Roger E. G., Santagostino, Elena, Meijers, Joost C. M.

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 369 KB

english, 2013

36

Systematic Review of the Role of FVIII Concentrates in Inhibitor Development in Previously Untreated Patients with Severe Hemophilia A: A 2013 Update

Franchini, Massimo, Coppola, Antonio, Rocino, Angiola, Santagostino, Elena, Tagliaferri, Annarita, Zanon, Ezio, Morfini, Massimo

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2013

Language:

english

File:

PDF, 407 KB

english, 2013

37

More on the Lack of Correlation between Terra Expression and Telomere Length

Vitelli, Valerio, Falvo, Paolo, Khoriauli, Lela, Smirnova, Alexandra, Gamba, Riccardo, Santagostino, Marco, Nergadze, Solomon George, Giulotto, Elena

Journal:

Frontiers in Oncology

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

38

Hemophilia A and Hemophilia B: Different Types of Diseases?

Santagostino, Elena, Fasulo, Maria

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2013

Language:

english

File:

PDF, 127 KB

english, 2013

39

The prognostic value of plasma fibrinogen concentrations of patients with ST-elevation myocardial infarction and treated by primary percutaneous coronary intervention: A cautionary message

Ferraro, Simona, Santagostino, Matteo, Marano, Giuseppe, Colli, Elena, Vendramin, Chiara, Maffé, Stefano, Rossi, Lidia, Galvani, Marcello, Panteghini, Mauro, Bongo, Angelo S.

Journal:

Scandinavian Journal of Clinical & Laboratory Investigation

Year:

2012

Language:

english

File:

PDF, 209 KB

english, 2012

40

Recombinant activated factor VII in the treatment of bleeds and for the prevention of surgery-related bleeding in congenital haemophilia with inhibitors

Santagostino, Elena, Escobar, Miguel, Ozelo, Margareth, Solimeno, Luigi, Arkhammar, Per, Lee, Hye Youn, Rosu, Gabriela, Giangrande, Paul

Journal:

Year:

2015

Language:

english

File:

PDF, 215 KB

english, 2015

41

Managing the Pediatric Patient and the Adolescent/Adult Transition

Valentino, Leonard, Santagostino, Elena, Blanchette, Victor, van den Berg, Marijke

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

42

Shorter Survival of SDF1‐3′A/3′A Homozygotes Linked to CD4 + T Cell Decrease in Advanced Human Immunodeficiency Virus Type 1 Infection

Brambilla, Andrea, Villa, Chiara, Rizzardi, GianPaolo, Veglia, Fabrizio, Ghezzi, Silvia, Lazzarin, Adriano, Cusini, Marco, Muratori, Simona, Santagostino, Elena, Gringeri, Alessandro, Louie, Leslie G.

Journal:

The Journal of Infectious Diseases

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

43

Beyond patient benefit: clinical development in hemophilia

Auerswald, Günter, Šalek, Silva Zupančić, Benson, Gary, Elezović, Ivo, Lambert, Thierry, Morfini, Massimo, Pasi, John, Remor, Eduardo, Santagostino, Elena, Salaj, Peter, Ljung, Rolf

Journal:

Hematology (American Society of Hematology)

Year:

2012

Language:

english

File:

PDF, 166 KB

english, 2012

44

Rare mutations in a domain crucial for V3-loopstructure prevail in replicating HIV from long-term non-progressors

Menzo, Stefano, Sampaolesi, Riccardo, Vicenzi, Elisa, Santagostino, Elena, Liuzzi, Giuseppina, Chirianni, Antonio, Piazza, Marcello, Cohen, Oren J., Bagnarelli, Patrizia, Clementi, Massimo

Journal:

Year:

1998

File:

PDF, 553 KB

1998

45

Rare mutations in a domain crucial for V3-loopstructure prevail in replicating HIV from long-term non-progressors

Menzo, Stefano, Sampaolesi, Riccardo, Vicenzi, Elisa, Santagostino, Elena, Liuzzi, Giuseppina, Chirianni, Antonio, Piazza, Marcello, Cohen, Oren J., Bagnarelli, Patrizia, Clementi, Massimo

Journal:

Year:

1998

Language:

english

File:

PDF, 553 KB

english, 1998

46

High serum sclerostin levels in children with haemophilia A

Giordano, Paola, Brunetti, Giacomina, Lassandro, Giuseppe, Notarangelo, Lucia D., Luciani, Matteo, Mura, Rosa M., Lazzareschi, Ilaria, Santagostino, Elena, Piacente, Laura, Ventura, Annamaria, Cavallo

Journal:

British Journal of Haematology

Year:

2016

Language:

english

File:

PDF, 69 KB

english, 2016

47

Innovative Pharmacological Therapies for the Hemophilias Not Based on Deficient Factor Replacement

Mannucci, Pier, Mancuso, Maria, Santagostino, Elena, Franchini, Massimo

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2016

Language:

english

File:

PDF, 122 KB

english, 2016

48

Turoctocog alfa in the treatment of individuals with hemophilia A: review of quality of life data collected in Phase III trials

Seremetis, Stephanie, Kulkarni, Roshni, Regnault, Antoine, Santagostino, Elena

Journal:

Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 820 KB

english, 2015

49

Rationale for individualizing haemophilia care

Sørensen, Benny, Auerswald, Günter, Benson, Gary, Elezović, Ivo, Felder, Markus, Lambert, Thierry, Morfini, Massimo, Remor, Eduardo, Salaj, Peter, Santagostino, Elena, Šalek, Silva Z., Ljung, Rolf

Journal:

Blood Coagulation & Fibrinolysis

Year:

2015

Language:

english

File:

PDF, 215 KB

english, 2015

50

Transforming the treatment for hemophilia B patients: update on the clinical development of recombinant fusion protein linking recombinant coagulation factor IX with recombinant albumin (rIX-FP)

Santagostino, Elena

Journal:

Thrombosis Research

Year:

2016

Language:

english

File:

PDF, 637 KB

english, 2016