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51

Antitumor activity of suramin in hormone-refractory prostate cancer controlling for hydrocortisone treatment and flutamide withdrawal as potentially confounding variables

Nancy A. Dawson, Michael R. Cooper, William D. Figg, Donna J. Headlee, Alain Thibault, Raymond C. Bergan, Seth M. Steinberg, Edward A. Sausville, Charles E. Myers, Oliver Sartor

Journal:

Year:

1995

Language:

english

File:

PDF, 965 KB

english, 1995

52

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

Nau, Marion M., Brooks, Burke J., Battey, James, Sausville, Edward, Gazdar, Adi F., Kirsch, Ilan R., McBride, O. Wesley, Bertness, Virginia, Hollis, Gregory F., Minna, John D.

Journal:

Year:

1985

File:

PDF, 624 KB

1985

53

Altered physical state of p21bcr???abl in tyrphostin AG957-treated K562 cells

Kaur, Gurmeet, Sausville, Edward A

Journal:

Anti-Cancer Drugs

Year:

1996

File:

PDF, 642 KB

1996

54

Flavopiridol Induces Apoptosis in Chronic Lymphocytic Leukemia Cells Via Activation of Caspase-3 Without Evidence of bcl-2 Modulation or Dependence on Functional p53

Byrd, John C., Shinn, Charlotte, Waselenko, Jamie K., Fuchs, Ephraim J., Lehman, Teresa A., Nguyen, Phuong L., Flinn, Ian W., Diehl, Louis F., Sausville, Edward, Grever, Michael R.

Journal:

Year:

1998

File:

PDF, 636 KB

1998

55

A protein expression database for the molecular pharmacology of cancer

Dr. Timothy G. Myers, N. Leigh Anderson, Mark Waltham, Guang Li, John K. Buolamwini, Dominic A. Scudiero, Kenneth D. Paull, Edward A. Sausville, Dr. John N. Weinstein

Journal:

ELECTROPHORESIS

Year:

1997

Language:

english

File:

PDF, 1.01 MB

english, 1997

56

Targetable HPMA Copolymer–Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy

Mark P. Borgman, Abhijit Ray, Rohit B. Kolhatkar, Edward A. Sausville, Angelika M. Burger, Hamidreza Ghandehari

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 345 KB

english, 2009

57

Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein

Joachim B. Schnier, Gurmet Kaur, Astrid Kaiser, Sherman F. Stinson, Edward A. Sausville, John Gardner, Kayoko Nishi, E.Morton Bradbury, Adrian M. Senderowicz

Journal:

Year:

1999

Language:

english

File:

PDF, 318 KB

english, 1999

58

Biodistribution of HPMA Copolymer-Aminohexylgeldanamycin-RGDfK Conjugates for Prostate Cancer Drug Delivery

Borgman, Mark P., Aras, Omer, Geyser-Stoops, Sandra, Sausville, Edward A., Ghandehari, Hamidreza

Journal:

Molecular Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 1.05 MB

english, 2009

59

Cytotoxic drugs: past, present and future

Newell, Herbie, Sausville, Edward

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 351 KB

english, 2016

60

Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma

Nathenson, Michael J, Barysauskas, Constance M, Nathenson, Robert A, Regine, William F, Hanna, Nader, Sausville, Edward

Journal:

World Journal of Surgical Oncology

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

61

Quantitative determination of perifosine, a novel alkylphosphocholine anticancer agent, in human plasma by reversed-phase liquid chromatography–electrospray mass spectrometry

Eunhee W Woo, Richard Messmann, Edward A Sausville, William D Figg

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

62

UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism

John C Byrd, Charlotte Shinn, Carl R Willis, Ian W Flinn, Theresa Lehman, Edward Sausville, David Lucas, Michael R Grever

Journal:

Experimental Hematology

Year:

2001

Language:

english

File:

PDF, 100 KB

english, 2001

63

Flavopiridol, a Novel Cyclin-Dependent Kinase Inhibitor, in Clinical Development

Zhai, Suoping, Senderowicz, Adrian M, Sausville, Edward A, Figg, William D

Journal:

Annals of Pharmacotherapy

Year:

2002

Language:

english

File:

PDF, 278 KB

english, 2002

64

Promises from Trametinib in RAF Active Tumors

Sausville, Edward A.

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 123 KB

english, 2012

65

Bilateral Adrenal Hemorrhage and Adrenal Insufficiency in a Patient with Lymphomatous Adrenal Infiltration Following Administration of a Fusion Toxin (DAB486 Interleukin-2)

Cohen, Roger, Jaffe, Elaine S., Stetler-Stevenson, Mary-Alice, Sausville, Edward A., DeNigris, Ellen C., Woodworth, Thasia, Foss, Francine M.

Journal:

Journal of Immunotherapy

Year:

1994

File:

PDF, 448 KB

1994

66

Cell microarray platform for anticancer drug development

Min-Jung Lee, Eun Joo Chung, Sunmin Lee, Joon-Yong Chung, William G. Telford, Edward A. Sausville, Ivana Gojo, Judith E. Karp, Steven D. Gore, Veena Kapoor, Yeong Sang Kim, Shivaani Kummar, Martin Gut

Journal:

Drug Development Research

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

67

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity

Conrad Kunick, Christiane Schultz, Thomas Lemcke, Daniel W Zaharevitz, Rick Gussio, Ravi K Jalluri, Edward A Sausville, Maryse Leost, Laurent Meijer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

68

Preclinical evaluation of 9-chloro-2-methylellipticinium acetate alone and in combination with conventional anticancer drugs for the treatment of human brain tumor xenografts

Francisco Arguello, Mark A. Alexander, John F. Greene Jr., Sherman F. Stinson, Jean L. Jorden, Erik M. Smith, Naina T. Kalavar, W. Gregory Alvord, Richard L. Klabansky, Edward A. Sausville

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1998

Language:

english

File:

PDF, 401 KB

english, 1998

69

The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

Akrit Sodhi, Risa Chaisuparat, Jiadi Hu, Amanda K. Ramsdell, Brendan D. Manning, Edward A. Sausville, Earl T. Sawai, Alfredo Molinolo, J. Silvio Gutkind, Silvia Montaner

Journal:

Year:

2006

Language:

english

File:

PDF, 940 KB

english, 2006

70

Imatinib for chronic myelogenous leukaemia: a 9 or 24 carat gold standard?

Edward A Sausville

Journal:

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

71

Targeting of CDK9 with indirubin 3’-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice

Medina-Moreno, Sandra, Dowling, Thomas C., Zapata, Juan C., Le, Nhut M., Sausville, Edward, Bryant, Joseph, Redfield, Robert R., Heredia, Alonso, Kashanchi, Fatah

Journal:

Year:

2017

Language:

english

File:

PDF, 945 KB

english, 2017

72

A high-performance liquid chromatography method using ultraviolet and fluorescence detection for the quantitation of UCN-01, 7-hydroxystaurosporine, from human plasma and saliva

Kenneth S. Bauer, Richard M. Lush, Michelle A. Rudek, Carolyn Shih, Edward Sausville, William D. Figg

Journal:

Biomedical Chromatography

Year:

2000

Language:

english

File:

PDF, 70 KB

english, 2000

73

ChemInform Abstract: Synthesis and Antitumor Evaluation of 4-Bromophenyl Semicarbazones.

Surendra N. Pandeya, Perumal Yogeeswari, Edward A. Sausville, Anthony B. Mauger, Ven L. Narayanan

Journal:

Year:

2002

File:

PDF, 27 KB

2002

74

A phase I trial of UCN-01 and prednisone in patients with refractory solid tumors and lymphomas

Shivaani Kummar, Martin E. Gutierrez, Erin R. Gardner, William D. Figg, Giovanni Melillo, Janet Dancey, Edward A. Sausville, Barbara A. Conley, Anthony J. Murgo, James H. Doroshow

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

75

Aurora kinases dawn as cancer drug targets

Sausville, Edward A

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 490 KB

english, 2004

76

Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells: Correlation with decreased H1 kinase activity

Peter J. Worland, Gurmeet Kaur, Maryalice Stetler-Stevenson, Sandra Sebers, Oliver Sartor, Edward A. Sausville

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.02 MB

english, 1993

77

Interactive Effects of HDAC Inhibitors and TRAIL on Apoptosis Are Associated with Changes in Mitochondrial Functions and Expressions of Cell Cycle Regulatory Genes in Multiple Myeloma

Fandy, Tamer E., Shankar, Sharmila, Ross, Douglas D., Sausville, Edward, Srivastava, Rakesh K.

Journal:

Year:

2005

Language:

english

File:

PDF, 453 KB

english, 2005

78

Part 2 || RNA Damage and Inhibition of Neoplastic Endothelial Cell Growth: Effects of Human and Amphibian Ribonucleases

Dianne L. Newton, Gurmeet Kaur, Johng S. Rhim, Edward A. Sausville and Susanna M. Rybak

Journal:

Radiation Research

Year:

2001

Language:

english

File:

PDF, 684 KB

english, 2001

79

Clinical pharmacology and pharmacogenetics of flavopiridol 1-h i.v. infusion in patients with refractory neoplasms

Zhai, Suoping, Sausville, Edward A., Senderowicz, Adrian M., Ando, Yuichi, Headlee, Donna, Messmann, Richard A., Arbuck, Susan, Murgo, Anthony J., Melillo, Giovanni, Fuse, Eiichi, Figg, William D.

Journal:

Anti-Cancer Drugs

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

80

Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation

Yuehai Shen, Qian Xie, Monica Norberg, Edward Sausville, George Vande Woude, David Wenkert

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 291 KB

english, 2005

81

Antitumor Benzothiazoles. 8.1 Synthesis, Metabolic Formation, and Biological Properties of the C- and N-Oxidation Products of Antitumor 2-(4-Aminophenyl)benzothiazoles∇

Kashiyama, Eiji, Hutchinson, Ian, Chua, Mei-Sze, Stinson, Sherman F., Phillips, Lawrence R., Kaur, Gurmeet, Sausville, Edward A., Bradshaw, Tracey D., Westwell, Andrew D., Stevens, Malcolm F. G.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

82

Transcription profiling of gene expression in drug discovery and development: the NCI experience

Edward A. Sausville, Susan L. Holbeck

Journal:

European Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 461 KB

english, 2004

83

Tyrphostin induced growth inhibition

Kaur, Gurmeet, Gazit, Aviv, Levitzki, Alexander, Stowe, Emily, Cooney, David A, Sausville, Edward A

Journal:

Anti-Cancer Drugs

Year:

1994

File:

PDF, 722 KB

1994

84

Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity

Schwartz, Gary K., Dickson, Mark A., LoRusso, Patricia M., Sausville, Edward A., Maekawa, Yoshimi, Watanabe, Yasuo, Kashima, Naomi, Nakashima, Daisuke, Akinaga, Shiro

Journal:

Year:

2016

Language:

english

File:

PDF, 836 KB

english, 2016

85

Histopathologic Staging at Initial Diagnosis of Mycosis Fungoides and the Sézary Syndrome

Sausville, Edward A.

Journal:

Annals of Internal Medicine

Year:

1988

Language:

english

File:

PDF, 2.07 MB

english, 1988

86

Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines

Freije, José M.P., Lawrence, Julia A., Hollingshead, Melinda G., De La Rosa, Abel, Narayanan, Ven, Grever, Michael, Sausville, Edward A., Paull, Kenneth, Steeg, Patricia S.

Journal:

Nature Medicine

Year:

1997

File:

PDF, 693 KB

1997

87

Clinical Pharmacology of Flavopiridol Following a 72-Hour Continuous Infusion

Rudek, Michelle A, Bauer, Kenneth S, Lush, Richard M, Stinson, Sherman F, Senderowicz, Adrian M, Headlee, Donna J, Arbuck, Susan G, Cox, Michael C, Murgo, Anthony J, Sausville, Edward A, Figg, William

Journal:

Annals of Pharmacotherapy

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

88

FR901228 causes mitotic arrest but does not alter microtubule polymerization

Sandor, Victor, Robbins, April R, Robey, Rob, Myers, Tim, Sausville, Edward, Bates, Susan E, Sackett, Dan L

Journal:

Anti-Cancer Drugs

Year:

2000

Language:

english

File:

PDF, 273 KB

english, 2000

89

Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone – A novel class of compounds with potent activity against acute myeloid leukemia cells

Carter-Cooper, Brandon A., Fletcher, Steven, Ferraris, Dana, Choi, Eun Yong, Kronfli, Dahlia, Dash, Smaraki, Truong, Phuc, Sausville, Edward A., Lapidus, Rena G., Emadi, Ashkan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 747 KB

english, 2017

90

Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms

Sausville, Edward A., Arbuck, Susan G., Messmann, Richard, Headlee, Donna, Bauer, Kenneth S., Lush, Richard M., Murgo, Anthony, Figg, William D., Lahusen, Tyler, Jaken, Susan, Jing, Xiu-xian, Roberge,

Journal:

Journal of Clinical Oncology

Year:

2001

Language:

english

File:

PDF, 534 KB

english, 2001

91

Bortezomib with concurrent radiation therapy in head and neck squamous cell carcinoma

Angela A. Chang, Barbara A. Conley, Peter F. Lebowitz, Kevin A. Camphausen, David R. Gius, Zhong Chen, Edward A. Sausville, Carter Van Waes

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 36 KB

english, 2004

92

Selective toxicity of the tricyclic thiophene NSC 652287 in renal carcinoma cell lines: Differential accumulation and metabolism

Maria I Rivera, Sherman F Stinson, David T Vistica, Jean L Jorden, Susan Kenney, Edward A Sausville

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 280 KB

english, 1999

93

RNA Damage and Inhibition of Neoplastic Endothelial Cell Growth: Effects of Human and Amphibian Ribonucleases

Newton, Dianne L., Kaur, Gurmeet, Rhim, Johng S., Sausville, Edward A., Rybak, Susanna M.

Journal:

Radiation Research

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

94

Unique amplification of BCR-ABL1 gene fusion in a case of T-cell acute lymphoblastic leukemia

Koka, Rima, Bade, Najeebah A., Sausville, Edward A., Ning, Yi, Zou, Ying

Journal:

Molecular Cytogenetics

Year:

2017

Language:

english

File:

PDF, 817 KB

english, 2017

95

Involvement of signal transduction pathways in lung cancer biology

Dr. Jean Viallet, Edward A. Sausville

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 912 KB

english, 1996

96

Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells

Eileen Brantley, Smitha Antony, Glenda Kohlhagen, LingHua Meng, Keli Agama, Sherman F. Stinson, Edward A. Sausville, Yves Pommier

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 433 KB

english, 2006

97

Cytotoxicity and apoptosis of benzoquinones: redox cycling, cytochrome c release, and BAD protein expression

Gabriela Tudor, Peter Gutierrez, Angelica Aguilera-Gutierrez, Edward A Sausville

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 475 KB

english, 2003

98

A high-performance liquid chromatography method using ultraviolet detection for the quantitation of flavopiridol from human plasma

Suoping Zhai, Edward Sausville, William D. Figg

Journal:

Biomedical Chromatography

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

99

Bombesin receptor structure and expression in human lung carcinoma cell lines

Zahra Fathi, James W. Way, Martha H. Corjay, Jean Viallet, Edward A. Sausville, James F. Battey

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 1000 KB

english, 1996

100

Factors affecting the pharmacokinetic profile of MS-275, a novel histone deacetylase inhibitor, in patients with cancer

Milin R. Acharya, Judith E. Karp, Edward A. Sausville, Kyunghwa Hwang, Qin Ryan, Ivana Gojo, Jűrgen Venitz, William D. Figg, Alex Sparreboom

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 318 KB

english, 2006

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