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51

4-Aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV

Joseph L. Duffy, Brian A. Kirk, Liping Wang, George J. Eiermann, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Alexsandr Petrov, Giovanna Scapin, Joseph K. Wu, Nan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

52

Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin

Tesfaye Biftu, Giovanna Scapin, Suresh Singh, Dennis Feng, Joe W. Becker, George Eiermann, Huaibing He, Kathy Lyons, Sangita Patel, Aleksandr Petrov, Ranabir Sinha-Roy, Bei Zhang, Joseph Wu, Xiaoping

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 364 KB

english, 2007

53

Recent results from the MAGIC telescope

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2008

Language:

english

File:

PDF, 894 KB

english, 2008

54

Lattice stabilization and enhanced diffraction in human p38α crystals by protein engineering

Sangita B Patel, Patricia M Cameron, Betsy Frantz-Wattley, Edward O'Neill, Joseph W Becker, Giovanna Scapin

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2004

Language:

english

File:

PDF, 554 KB

english, 2004

55

Self-assembly and structural characterization of Echinococcus granulosus antigen B recombinant subunit oligomers

Karina M. Monteiro, Sandra M.N. Scapin, Marcos V.A.S. Navarro, Nilson I.T. Zanchin, Mateus B. Cardoso, Nádya P. da Silveira, Paulo F.B. Gonçalves, Hubert K. Stassen, Arnaldo Zaha, Henrique B. Ferreira

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

56

Modeling assisted rational design of novel, potent, and selective pyrrolopyrimidine DPP-4 inhibitors

Ying-Duo Gao, Dennis Feng, Robert P. Sheridan, Giovanna Scapin, Sangita B. Patel, Joseph K. Wu, Xiaoping Zhang, Ranabir Sinha-Roy, Nancy A. Thornberry, Ann E. Weber, Tesfaye Biftu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 182 KB

english, 2007

57

Design, synthesis, and biological evaluation of triazolopiperazine-based β-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors

Jennifer E. Kowalchick, Barbara Leiting, KellyAnn D. Pryor, Frank Marsilio, Joseph K. Wu, Huaibing He, Kathryn A. Lyons, George J. Eiermann, Aleksandr Petrov, Giovanna Scapin, Reshma A. Patel, Nancy A

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

58

4-Arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV

David E. Kaelin, Abigail L. Smenton, George J. Eiermann, Huaibing He, Barbara Leiting, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Alexsandr Petrov, Giovanna Scapin, Joseph K. Wu, Nancy A. Th

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

59

Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design

Gui-Bai Liang, Xiaoxia Qian, Tesfaye Biftu, Suresh Singh, Ying-Duo Gao, Giovanna Scapin, Sangita Patel, Barbara Leiting, Reshma Patel, Joseph Wu, Xiaoping Zhang, Nancy A. Thornberry, Ann E. Weber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 427 KB

english, 2008

60

Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors

Scott D. Edmondson, Anthony Mastracchio, Jason M. Cox, George J. Eiermann, Huaibing He, Kathryn A. Lyons, Reshma A. Patel, Sangita B. Patel, Aleksandr Petrov, Giovanna Scapin, Joseph K. Wu, Shiyao Xu,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 411 KB

english, 2009

61

Analysis of strain rate behavior of an Al 6061 T6 alloy

A. Manes, L. Peroni, M. Scapin, M. Giglio

Journal:

Procedia Engineering

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

62

Assessment of gamma radiolytic degradation in waste lubricating oil by GC/MS and UV/VIS

Marcos A. Scapin, Celina L. Duarte, José Oscar W.V. Bustillos, Ivone M. Sato

Journal:

Radiation Physics and Chemistry

Year:

2009

Language:

english

File:

PDF, 146 KB

english, 2009

63

Indium(III) bromide catalyzed one-pot synthesis of trichloromethylated tetrahydropyrimidinones

Marcos A.P. Martins, Marcos V.M. Teixeira, Wilson Cunico, Elisandra Scapin, Rodrigo Mayer, Claudio M.P. Pereira, Nilo Zanatta, Helio G. Bonacorso, Clóvis Peppe, Yao-Feng Yuan

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 266 KB

english, 2004

64

The ergonomic criteria and the ISO/DIS 9241-10 dialogue principles: a pilot comparison in an evaluation task

J.M.C Bastien, D.L Scapin, C Leulier

Journal:

Interacting with Computers

Year:

1999

Language:

english

File:

PDF, 244 KB

english, 1999

65

Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase

John E. Stelmach, Luping Liu, Sangita B. Patel, James V. Pivnichny, Giovanna Scapin, Suresh Singh, Cornelis E.C.A. Hop, Zhen Wang, John R. Strauss, Patricia M. Cameron, Elizabeth A. Nichols, Stephen J

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

66

The Structure of JNK3 in Complex with Small Molecule Inhibitors: Structural Basis for Potency and Selectivity

Giovanna Scapin, Sangita B. Patel, JeanMarie Lisnock, Joseph W. Becker, Philip V. LoGrasso

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 388 KB

english, 2003

67

Substrate binding and conformational changes of Clostridium glutamicum diaminopimelate dehydrogenase revealed by hydrogen/deuterium exchange and electrospray mass spectrometry

Fang Wang, Giovanna Scapin, John S. Blanchard, Ruth Hogue Angeletti

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 4.03 MB

english, 1998

68

Crystal structure of chicken liver basic fatty acid-binding protein at 2.7 Å resolution

Giovanna Scapin, Paola Spadon, Mario Mammi, Giuseppe Zanotti, Hugo L. Monaco

Journal:

Molecular and Cellular Biochemistry

Year:

1990

Language:

english

File:

PDF, 346 KB

english, 1990

69

Metergoline versus bromocriptine in the prevention of puerperal lactation

F. Scapin, S. Buonaccorsi, G. Tronconi, G. Pellicciotta, A. E. Pontiroli

Journal:

European Journal of Clinical Pharmacology

Year:

1982

Language:

english

File:

PDF, 382 KB

english, 1982

70

High resolution X-ray studies of mammalian intestinal and muscle fatty acid-binding proteins provide an opportunity for defining the chemical nature of fatty acid: protein interactions

Giovanna Scapin, Aideen C. M. Young, Arno Kromminga, Jacques H. Veerkamp, Jeffrey I. Gordon, James C. Sacchettini

Journal:

Molecular and Cellular Biochemistry

Year:

1993

Language:

english

File:

PDF, 825 KB

english, 1993

71

Determination of yttrium and lanthanum in zirconium dioxide by HPLC, X-ray fluorescence and neutron activation analyses

Y. V. França, F. Leitão, H. M. Shihomatsu, W. S. Scapin, N. M. P. de Moraes, V. L. Salvador, A. M. G. Figueiredo, E. N. S. Muccillo, R. Muccillo

Journal:

Chromatographia

Year:

1999

Language:

english

File:

PDF, 381 KB

english, 1999

72

Mild exercise training, cardioprotection and stress genes profile

Marina Marini, Rosa Lapalombella, Vittoria Margonato, Raffaella Ronchi, Michele Samaja, Cristina Scapin, Luisa Gorza, Tullia Maraldi, Paolo Carinci, Carlo Ventura, Arsenio Veicsteinas

Journal:

European Journal of Applied Physiology

Year:

2007

Language:

english

File:

PDF, 374 KB

english, 2007

73

Rearing, release and settlement prospect in Italy ofTorymus sinensis, the biological control agent of the chestnut gall waspDryocosmus kuriphilus

Ambra Quacchia, Seiichi Moriya, Giovanni Bosio, Ivano Scapin, Alberto Alma

Journal:

Year:

2008

Language:

english

File:

PDF, 294 KB

english, 2008

74

Accuracy of magnetic resonance in suspicious breast lesions: a systematic quantitative review and meta-analysis

Lidia Rosi Medeiros, Célia Scapin Duarte, Daniela Dornelles Rosa, Maria Isabel Edelweiss, Marcia Edelweiss, Fábio Rosa Silva, Erik Paul Winnnikow, Patrícia Duarte Simões Pires, Maria Inês Rosa

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

75

Uncertainty measurement evaluation of WDXRF and EDXRF techniques for the Si and Utotaldetermination in U3Si2nuclear fuel

Marcos A. Scapin, Vera L. R. Salvador, Marycel E. B. Cotrim, Maria A. F. Pires, Ivone M. Sato

Journal:

Journal of Radioanalytical and Nuclear Chemistry

Year:

2011

Language:

english

File:

PDF, 226 KB

english, 2011

76

Arterial and venous thrombosis in patients with von Willebrand’s disease: A critical review of the literature

A Girolami, F Tezza, M Scapin, S Vettore, A Casonato

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

77

Cellular distribution of Hsp70 expression in rat skeletal muscles. Effects of moderate exercise training and chronic hypoxia

Elena Tarricone, Cristina Scapin, Maurizio Vitadello, Fabio Esposito, Vittoria Margonato, Giuseppina Milano, Michele Samaja, Luisa Gorza

Journal:

Cell Stress and Chaperones

Year:

2008

Language:

english

File:

PDF, 630 KB

english, 2008

78

p38 MAP kinase inhibitors. Part 6: 2-Arylpyridazin-3-ones as templates for inhibitor design

Swaminathan R. Natarajan, Stephen T. Heller, Kiyean Nam, Suresh B. Singh, Giovanna Scapin, Sangita Patel, James E. Thompson, Catherine E. Fitzgerald, Stephen J. O’Keefe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

79

Increasing the expressive power of task analysis: Systematic comparison and empirical assessment of tool-supported task models

Sybille Caffiau, Dominique Scapin, Patrick Girard, Mickaël Baron, Francis Jambon

Journal:

Interacting with Computers

Year:

2010

Language:

english

File:

PDF, 3.25 MB

english, 2010

80

Synthesis of 1,1,1-trichloro[fluoro]-3-alken-2-ones using ionic liquids

Marcos A.P. Martins, Emerson A. Guarda, Clarissa P. Frizzo, Elisandra Scapin, Paulo Beck, Alexandre C. da Costa, Nilo Zanatta, Helio G. Bonacorso

Journal:

Journal of Molecular Catalysis A: Chemical

Year:

2007

Language:

english

File:

PDF, 164 KB

english, 2007

81

Molecular structure of pyrazolo[1,5-a]pyrimidines: X-ray diffractometry and theoretical study

Clarissa P. Frizzo, Elisandra Scapin, Patrick T. Campos, Dayse N. Moreira, Marcos A.P. Martins

Journal:

Journal of Molecular Structure

Year:

2009

Language:

english

File:

PDF, 533 KB

english, 2009

82

The mutant JAK2V617F allele burden in children with essential thrombocythemia

Luciana Teofili, Tonia Cenci, Maurizio Martini, Sara Capodimonti, Lorenza Torti, Fiorina Giona, Angela Amendola, Maria Luigia Randi, Maria Caterina Putti, Margherita Scapin, Giuseppe Leone, Luigi Mari

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

83

Congenital FX deficiency combined with other clotting defects or with other abnormalities: a critical evaluation of the literature

A. GIROLAMI, E. RUZZON, F. TEZZA, R. SCANDELLARI, M. SCAPIN, P. SCARPARO

Journal:

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

84

Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity

Fitzgerald, Catherine E, Patel, Sangita B, Becker, Joseph W, Cameron, Patricia M, Zaller, Dennis, Pikounis, Vasilis Bill, O'Keefe, Stephen J, Scapin, Giovanna

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 972 KB

english, 2003

85

Comparison of the effects of ACE inhibition with those of Angiotensin II receptor antagonism on systolic and diastolic myocardial stunning in isolated rabbit heart

Celina Morales, Manuel Rodríguez, Omar Scapín, Ricardo J. Gelpi

Journal:

Molecular and Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 96 KB

english, 1998

86

In vivointeraction of cells on poly L-(lactic acid) membranes containing plasticizer

D. R. M. Silva, S. M. N. Scapin, P. P. Joazeiro, M. C. Alberto-Rincon, R. M. Luciano, E. A. R. Duek

Journal:

Journal of Materials Science: Materials in Medicine

Year:

2002

Language:

english

File:

PDF, 1.64 MB

english, 2002

87

The structure of apo protein-tyrosine phosphatase 1B C215S mutant: More than just an S → O change

Giovanna Scapin, Sangita Patel, Vira Patel, Brian Kennedy, Ernest Asante-Appiah

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 559 KB

english, 2001

88

For the record: The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate

Maurizio Cirilli, Giovanna Scapin, Andrew Sutherland, John C. Vederas, John S. Blanchard

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 1.56 MB

english, 2000

89

Cholesterol metabolism in frog (Rana esculenta) liver: Seasonal and sex-related variations

G. Bruscalupi, F. Castellano, S. Scapin, A. Trentalance

Journal:

Year:

1989

Language:

english

File:

PDF, 318 KB

english, 1989

90

Phospholipid and fatty acid composition of frog (Rana esculenta) liver—a circannual study

S. Scapin, P. Baldini, P. Luly

Journal:

Year:

1990

Language:

english

File:

PDF, 626 KB

english, 1990

91

Annual variations in the binding of insulin to hepatic membranes of the frog Rana esculenta

Sergio Scapin, Sandra Incerpi

Journal:

General and Comparative Endocrinology

Year:

1992

Language:

english

File:

PDF, 872 KB

english, 1992

92

Glycogen phosphorylase activity in the liver of the frog Rana esculenta

Sergio Scapin, Graziano Di Giuseppe

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1993

Language:

english

File:

PDF, 621 KB

english, 1993

93

Seasonal variations of glycogen synthase and phosphorylase activities in the liver of the frog Rana esculenta

Sergio Scapin, Graziano Di Giuseppe

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1994

Language:

english

File:

PDF, 617 KB

english, 1994

94

Parameters identification in strain-rate and thermal sensitive visco-plastic material model for an alumina dispersion strengthened copper

M. Scapin, L. Peroni, M. Peroni

Journal:

International Journal of Impact Engineering

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

95

Correlation between cytosolic Ca2+ concentration, protein phosphorylation and platelet secretion

L. Dalla Via, M. Stimamiglio, M. Scapin, L. Cesaro, R. Deana

Journal:

Year:

1996

Language:

english

File:

PDF, 4.81 MB

english, 1996

96

Structural studies on human muscle fatty acid binding protein at 1.4 å resolution: binding interactions with three C18 fatty acids

Aideen CM Young, Giovanna Scapin, Arno Kromminga, Sangita B Patel, Jacques H Veerkamp, James C Sacchettini

Journal:

Year:

1994

Language:

english

File:

PDF, 1.46 MB

english, 1994

97

Structural biology in drug design: selective protein kinase inhibitors

Giovanna Scapin

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

98

Grp94 acts as a mediator of curcumin-induced antioxidant defence in myogenic cells

Paola Pizzo, Cristina Scapin, Maurizio Vitadello, Cristina Florean, Luisa Gorza

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 974 KB

english, 2010

99

Syntactic Iron Foams – On Deformation Mechanisms and Strain-Rate Dependence of Compressive Properties

Lorenzo Peroni, Martina Scapin, Massimiliano Avalle, Jörg Weise, Dirk Lehmhus, Joachim Baumeister, Matthias Busse

Journal:

Advanced Engineering Materials

Year:

2012

Language:

english

File:

PDF, 804 KB

english, 2012

100

Primary Structure and Crystallization of Orotate Phosphoribosyltransferase from Salmonella typhimurium

Giovanna Scapin, James C. Sacchettini, Andrea Dessen, Mohit Bhatia, Charles Grubmeyer

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 275 KB

1993