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1

Regulation of Expression of Interleukin-6 : Molecular and Clinical Studies

ANURADHA RAY, STEPHEN B. TATTER, UMA SANTHANAM, DAVID C. HELFGOTT, LESTER T. MAY, PRAVINKUMAR B. SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 661 KB

english, 1989

2

Expression and function of interleukin-6 in epithelial cells

James Krueger, Anuradha Ray, Igor Tamm, Pravinkumar B. Sehgal

Journal:

Journal of Cellular Biochemistry

Year:

1991

Language:

english

File:

PDF, 714 KB

english, 1991

3

Dexamethasone inhibits feedback regulation of the mitogenic activity of tumor necrosis factor, interleukin-1, and epidermal growth factor in human fibroblasts

Dr. Masayoshi Kohase, Dorothy Henriksen-Destefano, Pravinkumar B. Sehgal, Jan Vilĉek

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 900 KB

english, 1987

4

Interleukin-6: Molecular Pathophysiology.

Sehgal, Pravinkumar B.

Journal:

The Journal of Investigative Dermatology

Year:

1990

File:

PDF, 1.35 MB

1990

5

Achieving a Desired Esthetic Outcome for a Single-Tooth Implant Restoration with Tissue Excess Using a Multidisciplinary Treatment Approach: A Clinical Report

Ankur Gupta, Rajat Sehgal, Mohana Tagore, Pravinkumar G. Patil, Bhavesh Kothari, Santosh Puri

Journal:

Journal of Prosthodontics

Year:

2011

Language:

english

File:

PDF, 623 KB

english, 2011

6

DRB-induced premature termination of late adenovirus transcription

Fraser, Nigel W., Sehgal, Pravinkumar B., Darnell, James E.

Journal:

Year:

1978

File:

PDF, 431 KB

1978

7

Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species

Sehgal, Pravinkumar B., Sagar, Anurag D.

Journal:

Year:

1980

File:

PDF, 364 KB

1980

8

Studies of the Effect of Cyclosporine in Psoriasis In Vivo: Combined Effects on Activated T Lymphocytes and Epidermal Regenerative Maturation.

Gottlieb, Alice B., Grossman, Rachel M., Khandke, Lakshmi, Carter, D. Martin, Sehgal, Pravinkumar B., Fu, Shu Man, Granelli-Piperno, Angela, Rivas, Miriam, Barazani, Lance, Krueger, James G.

Journal:

The Journal of Investigative Dermatology

Year:

1992

File:

PDF, 4.26 MB

1992

9

Interferon-β-related DNA on human chromosome 4

Anurag D. Sagar, Pravinkumar B. Sehgal, Lester T. May, Doris L. Slate, Lester Shulman, Peter E. Barker, Frank H. Ruddle

Journal:

Somatic Cell and Molecular Genetics

Year:

1985

Language:

english

File:

PDF, 576 KB

english, 1985

10

The interferon genes

Pravinkumar B. Sehgal

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1982

Language:

english

File:

PDF, 1.25 MB

english, 1982

11

Interferons

Igor Tamm, Pravinkumar B. Sehgal

Journal:

The American Journal of Medicine

Year:

1979

Language:

english

File:

PDF, 386 KB

english, 1979

12

Post-translational modifications of human interleukin-6

Uma Santhanam, John Ghrayeb, Pravinkumar B. Sehgal, Lester T. May

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 2.01 MB

english, 1989

13

Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation

Lester T. May, Gabriella Torcia, Federico Cozzolino, Anuradha Ray, Stephen B. Tatter, Uma Santhanam, Pravinkumar B. Sehgal, David Stern

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 942 KB

english, 1989

14

Halogenated benzimidazole ribosides: Novel inhibitors of RNA synthesis

Pravinkumar B. Sehgal, Igor Tamm

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 1.69 MB

english, 1978

15

Role of interleukin-6 in regulating synthesis of C-reactive protein and serum amyloid A in human hepatoma cell lines

Mahrukh K. Ganapathi, Lester T. May, Debra Schultz, Anne Brabenec, Joel Weinstein, Pravinkumar B. Sehgal, Irving Kushner

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 516 KB

english, 1988

16

Phosphorylation of secreted forms of human β2-interferon/hepatocyte stimulating factor/interleukin-6

Lester T. May, Uma Santhanam, Stephen B. Tatter, Nina Bhardwaj, John Ghrayeb, Pravinkumar B. Sehgal

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 1.34 MB

english, 1988

17

Expression of the native a and β interferon genes in human cells

Lester T. May, Pravinkumar B. Sehgal, K.Steven Laforge, Masayori Inouye

Journal:

Year:

1983

Language:

english

File:

PDF, 1.27 MB

english, 1983

18

SYNTHESIS, STRUCTURE, AND FUNCTION OF POLY(I) · POLY(C)-INDUCED HUMAN FIBROBLAST INTERFERON mRNA

Pravinkumar B. Sehgal, Igor Tamm

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 433 KB

english, 1980

19

On the mechanism of enhancement of human interferon production by actinomycin D and cycloheximide

Pravinkumar B. Sehgal, Igor Tamm, Jan Vilček

Journal:

Year:

1976

Language:

english

File:

PDF, 336 KB

english, 1976

20

Regulation of human interferon production: II. Inhibition of interferon messenger RNA synthesis by 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole

Pravinkumar B. Sehgal, Igor Tamm, Jan Vilček

Journal:

Year:

1976

Language:

english

File:

PDF, 215 KB

english, 1976

21

Regulation of human interferon production: I. Superinduction by 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole

Pravinkumar B. Sehgal, Igor Tamm, Jan Vilček

Journal:

Year:

1976

Language:

english

File:

PDF, 959 KB

english, 1976

22

Superinduction of human fibroblast interferon production: Further evidence for increased stability of interferon mRNA

Pravinkumar B. Sehgal, Douglas S. Lyles, Igor Tamm

Journal:

Year:

1978

Language:

english

File:

PDF, 1.14 MB

english, 1978

23

Two mechanisms contribute to the superinduction of poly(I)·poly(C)-induced human fibroblast interferon production

Pravinkumar B. Sehgal, Igor Tamm

Journal:

Year:

1979

Language:

english

File:

PDF, 403 KB

english, 1979

24

Early Ad-2 transcription units: Only promoter-proximal RNA continues to be made in the presence of DRB

Pravinkumar B. Sehgal, Nigel W. Fraser, James E. Darnell Jr.

Journal:

Year:

1979

Language:

english

File:

PDF, 612 KB

english, 1979

25

Regulation of the stability of human β interferon mRNA in poly(I)·poly(C)-induced diploid fibroblasts: Anchorage independence of the shutoff mechanism

Pravinkumar B. Sehgal

Journal:

Year:

1981

Language:

english

File:

PDF, 685 KB

english, 1981

26

A Merging of Disciplines

PRAVINKUMAR B. SEHGAL, GERD GRIENINGER, GIOVANNA TOSATO

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 85 KB

english, 1989

27

Multiple Forms of Human Interleukin-6 : Phosphoglycoproteins Secreted by Many Different Tissues

LESTER T. MAY, UMA SANTHANAM, STEPHEN B. TATTER, JOHN GHRAYEB, PRAVINKUMAR B. SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 427 KB

english, 1989

28

Production of IL-6 by Keratinocytes : Implications for Epidermal Inflammation and Immunity

THOMAS S. KUPPER, KENT MIN, PRAVINKUMAR SEHGAL, HITOSHI MIZUTANI, NICHOLAS BIRCHALL, ANURADHA RAY, LESTER MAY

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.42 MB

english, 1989

29

Identification and Characterization of Interleukin-6/Interferon-β2 in Synovial Effusions of Patients with Rheumatoid Arthritis and Other Arthritides

NINA BHARDWAJ, UMA SANTHANAM, LISA L. LAU, STEPHEN B. TATTER, JOHN GHRAYEB, MARCOS RIVELIS, RALPH M. STEINMAN, PRAVINKUMAR B. SEHGAL, LESTER T. MAY

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 94 KB

english, 1989

30

Interleukin-1 and Interleukin-6 Synergize to Increase Plasma Amyloid P and C3 Concentrations in the Mouse

LYLE L. MOLDAWER, E. DIANE BUSHMAN, ANNABEL BARBER, MICHAEL A. MARANO, CHRISTOPHER KEOGH, YUMAN FONG, DAVID C. HELFGOTT, LESTER T. MAY, PRAVINKUMAR SEHGAL, STEPHEN F. LOWRY

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 174 KB

english, 1989

31

Interferon-β2/Interleukin-6 in Plasma and Body Fluids during Acute Bacterial Infection

DAVID C. HELFGOTT, ROBERT H. CLARICK, LESTER T. MAY, PRAVINKUMAR B. SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 97 KB

english, 1989

32

Cytokine-induced Production of IL-6 by Freshly Explanted Human Endometrial Stromal Cells : Modulation by Estradiol-17β

SIAMAK S. TABIBZADEH, UMA SANTHANAM, LESTER MAY, PRAVINKUMAR SEHGAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 77 KB

english, 1989

33

News and comment

May, Lester T., Shaw, James E., Khanna, Ashwani K., Zabriskie, John B., Sehgal, Pravinkumar B.

Journal:

American Journal of Orthodontics and Dentofacial Orthopedics

Year:

1988

Language:

english

File:

PDF, 171 KB

english, 1988

34

Marked cell-type-specific differences in glycosylation of human interleukin-6

May, Lester T., Shaw, James E., Khanna, Ashwani K., Zabriskie, John B., Sehgal, Pravinkumar B.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.73 MB

english, 1991

35

Interferon action: Two (2′-5′) (A)n synthetases specified by distinct mRNAs in Ehrlich ascites tumor cells treated with interferon

Laurent, Georges St., Yoshie, Osamu, Floyd-Smith, Georgia, Samanta, Himadri, Sehgal, Pravinkumar B., Lengyel, Peter

Journal:

Year:

1983

Language:

english

File:

PDF, 2.02 MB

english, 1983

36

The inhibition of DRB (5,6-dichloro-1-β-d-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells

Sehgal, Pravinkumar B., Darnell Jr., James E., Tamm, Igor

Journal:

Year:

1976

Language:

english

File:

PDF, 588 KB

english, 1976

37

Cytokines in normal and abnormal parturition: Elevated amniotic fluid interleukin-6 levels in women with premature rupture of membranes associated with intrauterine infection

Santhanam, Uma, Avila, Cecilia, Romero, Roberto, Viguet, Huguette, Ida, Nobuo, Sakurai, Shingou, Sehgal, Pravinkumar B.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

38

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

Kohase, Masayoshi, Henriksen-DeStefano, Dorothy, May, Lester T., Vilček, Jan, Sehgal, Pravinkumar B.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.66 MB

english, 1986

39

The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and Gram stain in patients with preterm labor and intact membranes

Romero, Roberto, Yoon, Bo Hyun, Mazor, Moshe, Gomez, Ricardo, Diamond, Michael P., Kenney, John S., Ramirez, Marcelo, Fidel, Paul L., Sorokin, Yoram, Cotton, David, Sehgal, Pravinkumar

Journal:

American Journal of Obstetrics and Gynecology

Year:

1993

Language:

english

File:

PDF, 1.63 MB

english, 1993

40

Interleukin-6 and 12-O-tetradecanoyl Phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells

Tamm, Igor, Cardinale, Irma, Sehgal, Pravinkumar B.

Journal:

Year:

1991

Language:

english

File:

PDF, 6.66 MB

english, 1991

41

Regional localization of the interferon-β2B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21

Ferguson-Smith, Anne C., Chen, Yi-Feng, Newman, Marilyn S., May, Lester T., Sehgal, Pravinkumar B., Ruddle, Frank H.

Journal:

Year:

1988

Language:

english

File:

PDF, 2.91 MB

english, 1988

42

A comparative study of the diagnostic performance of amniotic fluid glucose, white blood cell count, interleukin-6, and Gram stain in the detection of microbial invasion in patients with preterm premature rupture of membranes

Romero, Roberto, Yoon, Bo Hyun, Mazor, Moshe, Gomez, Ricardo, Gonzalez, Rogelio, Diamond, Michael P., Baumann, Peter, Araneda, Heriberto, Kenney, John S., Cotton, David B., Sehgal, Pravinkumar

Journal:

American Journal of Obstetrics and Gynecology

Year:

1993

Language:

english

File:

PDF, 1.73 MB

english, 1993

43

[Part 1: Biological Sciences] || Unusually Long mRNA Species Coding for Human α and β Interferons

Pravinkumar B. Sehgal, Lester T. May, K. Steven LaForge and Masayori Inouye

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.46 MB

english, 1982

44

[Part 1: Biological Sciences] || Isolation of Novel Human Genomic DNA Clones Related to Human Interferon-β1cDNA

Pravinkumar B. Sehgal, Lester T. May, Anurag D. Sagar, K. Steven LaForge and Masayori Inouye

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.38 MB

english, 1983

45

[Part 1: Biological Sciences] || Internal Duplication in Human α1and β1Interferons

Bruce W. Erickson, Lester T. May and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 909 KB

english, 1984

46

Significance of Similarities in Patterns: An Application to β Interferon-Related DNA on Human Chromosome 2

Lester T. May, Frank R. Landsberger, Masayori Inouye and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 962 KB

english, 1985

47

Human Chromosome 7 Carries the β2Interferon Gene

Pravinkumar B. Sehgal, Asher Zilberstein, Rosa-Maria Ruggieri, Lester T. May, Anne Ferguson-Smith, Doris L. Slate, Michel Revel and Frank H. Ruddle

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 793 KB

english, 1986

48

Anti-β -interferon Antibodies Inhibit the Increased Expression of HLA-B7 mRNA in Tumor Necrosis Factor-Treated Human Fibroblasts: Structural Studies of the β2Interferon Involved

Lester T. May, David C. Helfgott and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.02 MB

english, 1986

49

Rapid Enhancement of β2-interferon/B-cell Differentiation Factor BSF-2 Gene Expression in Human Fibroblasts by Diacylglycerols and the Calcium Ionophore A23187

Pravinkumar B. Sehgal, Zenta Walther and Igor Tamm

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.22 MB

english, 1987

50

Activation of the Human ``β2-Interferon/Hepatocyte-Stimulating Factor/Interleukin 6'' Promoter by Cytokines, Viruses, and Second Messenger Agonists

Anuradha Ray, Stephen B. Tatter, Lester T. May and Pravinkumar B. Sehgal

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.51 MB

english, 1988