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1

The Signaling Adaptor Gab1 Regulates Cell Polarity by Acting as a PAR Protein Scaffold

Yang, Ziqiang, Xue, Bin, Umitsu, Masataka, Ikura, Mitsuhiko, Muthuswamy, Senthil K., Neel, Benjamin G.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.03 MB

english, 2012

2

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Jayanta Debnath, Senthil K. Muthuswamy, Joan S. Brugge

Journal:

Year:

2003

Language:

english

File:

PDF, 488 KB

english, 2003

3

Reinterpreting Polarity and Cancer: The changing landscape from tumor suppression to tumor promotion

Saito, Yasuhiro, Desai, Ridhdhi R., Muthuswamy, Senthil K.

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2018

Language:

english

File:

PDF, 6.80 MB

english, 2018

4

Illuminating the Center: Mechanisms Regulating Lumen Formation and Maintenance in Mammary Morphogenesis

Mauricio J. Reginato, Senthil K. Muthuswamy

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

5

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

Muthuswamy, Senthil K., Li, Dongmei, Lelievre, Sophie, Bissell, Mina J., Brugge, Joan S.

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 2.72 MB

english, 2001

6

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

Reginato, Mauricio J., Mills, Kenna R., Paulus, Jessica K., Lynch, Danielle K., Sgroi, Dennis C., Debnath, Jayanta, Muthuswamy, Senthil K., Brugge, Joan S.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 1.24 MB

english, 2003

7

Par6–aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control

Aranda, Victoria, Haire, Teresa, Nolan, Marissa E., Calarco, Joseph P., Rosenberg, Avi Z., Fawcett, James P., Pawson, Tony, Muthuswamy, Senthil K.

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.82 MB

english, 2006

8

Trastuzumab resistance: all roads lead to SRC

Muthuswamy, Senthil K

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

9

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors

Shizhen Emily Wang, Archana Narasanna, Marianela Perez-Torres, Bin Xiang, Frederick Y. Wu, Seungchan Yang, Graham Carpenter, Adi F. Gazdar, Senthil K. Muthuswamy, Carlos L. Arteaga

Journal:

Year:

2006

Language:

english

File:

PDF, 1.21 MB

english, 2006

10

A Brake Becomes an Accelerator: PTP1B—A New Therapeutic Target for Breast Cancer

Nicholas K. Tonks, Senthil K. Muthuswamy

Journal:

Year:

2007

Language:

english

File:

PDF, 156 KB

english, 2007

11

Polarity proteins regulate mammalian cell–cell junctions and cancer pathogenesis

Michael E Feigin, Senthil K Muthuswamy

Journal:

Current Opinion in Cell Biology

Year:

2009

Language:

english

File:

PDF, 529 KB

english, 2009

12

ErbB receptors and cell polarity: New pathways and paradigms for understanding cell migration and invasion

Michael E. Feigin, Senthil K. Muthuswamy

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

13

Cigarette suppresses the expression of P4Hα and vascular collagen production

Muthuswamy Raveendran, Duraisamy Senthil, Budi Utama, Ying Shen, Donald Dudley, Jian Wang, Yun Zhang, Xing Li Wang

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 2.04 MB

english, 2004

14

ErbB2 Makes β4 Integrin an Accomplice in Tumorigenesis

Senthil K. Muthuswamy

Journal:

Year:

2006

Language:

english

File:

PDF, 213 KB

english, 2006

15

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

Lixing Zhan, Avi Rosenberg, Kenneth C. Bergami, Min Yu, Zhenyu Xuan, Aron B. Jaffe, Craig Allred, Senthil K. Muthuswamy

Journal:

Year:

2008

Language:

english

File:

PDF, 1.92 MB

english, 2008

16

Cyfip1 Is a Putative Invasion Suppressor in Epithelial Cancers

Jose M. Silva, Elena Ezhkova, Javier Silva, Stephen Heart, Mireia Castillo, Yolanda Campos, Veronica Castro, Felix Bonilla, Carlos Cordon-Cardo, Senthil K. Muthuswamy, Scott Powers, Elaine Fuchs, Greg

Journal:

Year:

2009

Language:

english

File:

PDF, 3.64 MB

english, 2009

17

Endogenous nitric oxide activation protects against cigarette smoking induced apoptosis in endothelial cells

Muthuswamy Raveendran, Jing Wang, Duraisamy Senthil, Jian Wang, Budi Utama, Ying Shen, Donald Dudley, Yun Zhang, Xing Li Wang

Journal:

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

18

Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

Ling Huang, Senthil K Muthuswamy

Journal:

Current Opinion in Genetics & Development

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

19

ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

William M. Keyes, Matteo Pecoraro, Victoria Aranda, Emma Vernersson-Lindahl, Wangzhi Li, Hannes Vogel, Xuecui Guo, Elvin L. Garcia, Tatyana V. Michurina, Grigori Enikolopov, Senthil K. Muthuswamy, Ale

Journal:

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

20

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

Jayanta Debnath, Kenna R. Mills, Nicole L. Collins, Mauricio J. Reginato, Senthil K. Muthuswamy, Joan S. Brugge

Journal:

Year:

2002

Language:

english

File:

PDF, 1.34 MB

english, 2002

21

Erratum

Jayanta Debnath, Kenna R. Mills, Nicole L. Collins, Mauricio J. Reginato, Senthil K. Muthuswamy, Joan S. Brugge

Journal:

Year:

2002

Language:

english

File:

PDF, 20 KB

english, 2002

22

3D culture reveals a signaling network

Senthil K Muthuswamy

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

23

Genotype-Dependent Expression of Endothelial Nitric Oxide Synthase (eNOS) and Its Regulatory Proteins in Cultured Endothelial Cells

Senthil, Duraisamy, Raveendran, Muthuswamy, Shen, Ying H., Utama, Budi, Dudley, Donald, Wang, Jian, Wang, Xing Li

Journal:

DNA and Cell Biology

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

24

Cell Polarity as a Regulator of Cancer Cell Behavior Plasticity

Muthuswamy, Senthil K., Xue, Bin

Journal:

Annual Review of Cell and Developmental Biology

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

25

Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion

Xue, Bin, Krishnamurthy, Kannan, Allred, D. Craig, Muthuswamy, Senthil K.

Journal:

Nature Cell Biology

Year:

2012

Language:

english

File:

PDF, 2.77 MB

english, 2012

26

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

Anczuków, Olga, Rosenberg, Avi Z, Akerman, Martin, Das, Shipra, Zhan, Lixing, Karni, Rotem, Muthuswamy, Senthil K, Krainer, Adrian R

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

27

Disruption of the coordinate expression of muscle genes in a transfected BC 3 H1 myoblast cell line producing a low level of the adenovirus E1A transforming protein

Mymryk, Joe S., Oakes, Janice D., Muthuswamy, Senthil K., D'Amico, Pietro, Bayley, Stanley T., Lee, Raymond W. H.

Journal:

Biochemistry and Cell Biology

Year:

1992

Language:

english

File:

PDF, 1.41 MB

english, 1992

28

A Novel Phosphatidic Acid-Protein-tyrosine Phosphatase D2 Axis Is Essential for ERBB2 Signaling in Mammary Epithelial Cells

Ramesh, Mathangi, Krishnan, Navasona, Muthuswamy, Senthil K., Tonks, Nicholas K.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.52 MB

english, 2015

29

A New Tumor Suppressor That Regulates Tissue Architecture

Muthuswamy, Senthil K.

Journal:

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

30

Controlled Dimerization of ErbB Receptors Provides Evidence for Differential Signaling by Homo- and Heterodimers

Muthuswamy, Senthil K., Gilman, Michael, Brugge, Joan S.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.66 MB

english, 1999

31

SCRIBBLE is required for pregnancy-induced alveologenesis in the adult mammary gland

Baker, Leena, BeGora, Michael, Au Yeung, Faith, Feigin, Michael E., Rosenberg, Avi Z., Lowe, Scott W., Kislinger, Thomas, Muthuswamy, Senthil K.

Journal:

Journal of Cell Science

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

32

Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement

Milano, Daniel F., Ngai, Nicholas A., Muthuswamy, Senthil K., Asthagiri, Anand R.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

33

Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis

Webster, Marc A., Hutchinson, John N., Rauh, Michael J., Muthuswamy, Senthil K., Anton, Martina, Tortorice, Christopher G., Cardiff, Robert D., Graham, Frank L., Hassell, John A., Muller, William J.

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 2.25 MB

english, 1998

34

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Zheng, Weiyue, Umitsu, Masataka, Jagan, Ishaan, Tran, Charles W., Ishiyama, Noboru, BeGora, Michael, Araki, Kiyomi, Ohashi, Pamela S., Ikura, Mitsuhiko, Muthuswamy, Senthil K.

Journal:

Nature Cell Biology

Year:

2016

Language:

english

File:

PDF, 12.68 MB

english, 2016

35

Positive Quantitative Relationship between EMT and Contact-Initiated Sliding on Fiber-like Tracks

Milano, Daniel F., Natividad, Robert J., Saito, Yasuhiro, Luo, Catherine Y., Muthuswamy, Senthil K., Asthagiri, Anand R.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

36

The Mental Health Acute Assessment Team: a collaborative approach to treating mental health patients in the community

Faddy, Steven C, McLaughlin, Kevin J, Cox, Peta T, Muthuswamy, Senthil S

Journal:

Australasian Psychiatry

Year:

2017

Language:

english

File:

PDF, 380 KB

english, 2017

37

Bringing together the organoid field: from early beginnings to the road ahead

Muthuswamy, Senthil K.

Journal:

Development (The Company of Biologists)

Year:

2017

Language:

english

File:

PDF, 203 KB

english, 2017

38

[Advances in Cancer Research] Volume 64 || Activation Of The Src Family Of Tyrosine Kinases In Mammary Tumorigenesis

Muthuswamy, Senthil K.

Year:

1994

Language:

english

File:

PDF, 864 KB

english, 1994

39

Personalized RNA-medicine for pancreatic cancer

Gilles, Maud-Emmanuelle, Hao, Liangliang, Huang, Ling, Rupaimoole, Rajesha, Lopez-Casas, Pedro P., Pulver, Emilia, Jeong, Jong Cheol, Muthuswamy, Senthil K., Hidalgo, Manuel, Bhatia, Sangeeta N., Slac

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 9.70 MB

english, 2018

40

Organoid Models of Cancer Explode with Possibilities

Muthuswamy, Senthil K.

Journal:

Year:

2018

Language:

english

File:

PDF, 216 KB

english, 2018

41

Editorial overview: Cell differentiation and development: New kids in the block — new tools and concepts opening new doors in development

Götz, Magdalena, Muthuswamy, Senthil K

Journal:

Current Opinion in Cell Biology

Year:

2017

Language:

english

File:

PDF, 167 KB

english, 2017

42

SAE Technical Paper Series [SAE International Advances In Aviation Safety Conference & Exposition - (APR. 06, 1998)] SAE Technical Paper Series - A Hybrid Neuro-Fuzzy Based Fault Diagnostic Technique for Bearings Condition-Based Maintenance

Shirkhodaie, Amir, Muthuswamy, Senthil K., Saravanan, Siva S.

Year:

1998

Language:

english

File:

PDF, 588 KB

english, 1998

43

Support Needs of Family Caregivers of People who Experience Mental Illness and the Role of Mental Health Services

Shankar, Janki, Muthuswamy, Senthil Sonai

Journal:

Families in Society: The Journal of Contemporary Social Services

Year:

2007

Language:

english

File:

PDF, 96 KB

english, 2007

44

Golgi Stabilization, Not Its Front-Rear Bias, Is Associated with EMT-Enhanced Fibrillar Migration

Natividad, Robert J., Lalli, Mark L., Muthuswamy, Senthil K., Asthagiri, Anand R.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 978 KB

english, 2018

45

LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer

Saito, Yasuhiro, Li, Lewyn, Coyaud, Etienne, Luna, Augustin, Sander, Chris, Raught, Brian, Asara, John M., Brown, Myles, Muthuswamy, Senthil K.

Journal:

Year:

2019

Language:

english

File:

PDF, 9.81 MB

english, 2019

46

Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold

Ferguson, Fleur M., Liu, Yan, Harshbarger, Wayne, Huang, Ling, Wang, Jinhua, Deng, Xianming, Capuzzi, Stephen Joseph, Muratov, Eugene N., Tropsha, Alexander, Muthuswamy, Senthil, Westover, Kenneth Dal

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 867 KB

2020

47

Correction to âSynthesis and StructureâActivity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6 H -benzo[ e ]pyrimido[5,4- b ][1,4]diazepin-6-one Scaffoldâ

Ferguson, Fleur M., Liu, Yan, Harshbarger, Wayne, Huang, Ling, Wang, Jinhua, Deng, Xianming, Capuzzi, Stephen J., Muratov, Eugene N., Tropsha, Alexander, Muthuswamy, Senthil, Westover, Kenneth D., Gra

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 274 KB

2020

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