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51

Diastereoselective synthesis of chiral β-amino-α-hydroxy-H-phosphinates through hydrophosphinylation of α-amino aldehydes

Takehiro Yamagishi, Kenji Suemune, Tsutomu Yokomatsu, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

52

Novel syntheses of dibenzo[d,f]azonine and dibenzo[e,g]azecine systems

Shinzo Kano, Toshihisa Ogawa, Tsutomu Yokomatsu, Eiji Komiyama, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

1974

Language:

english

File:

PDF, 175 KB

english, 1974

53

A new facile diastereoconversion of 2-amino alcohols involving a novel cyclocarbamation

Shinzo Kano, Tsutomu Yokomatsu, Haruo Iwasawa, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 251 KB

english, 1987

54

Formation of 4-methylthio-2-phenyl-1-butene derivatives by the reaction of β-hydroxy-β-phenylsulfonium salt with base

Shinzo Kano, Tsutomu Yokomatsu, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

1978

Language:

english

File:

PDF, 119 KB

english, 1978

55

The structure of cularidine

Tetsuji Kametani, Shiroshi Shibuya, Chihiro Kibayashi, Shinichi Sasaki

Journal:

Tetrahedron Letters

Year:

1966

Language:

english

File:

PDF, 184 KB

english, 1966

56

Stereoselective β-N-glycosylation of 2,3-dideoxyribofuranose derivatives controlled by a methylenephosphonothioate functional group at the 3-position

Tsutomu Yokomatsu, Tomoyuki Sada, Takanori Shimizu, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 262 KB

english, 1998

57

Enantioselective synthesis of α-amino phosphonic acids by an application of stereoselective opening of homochiral dioxane acetals with triethyl phosphite

Tsutomu Yokomatsu, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1992

Language:

english

File:

PDF, 148 KB

english, 1992

58

Stereodivergent synthesis of β-amino-α-hydroxyphosphonic acid derivatives by lewis acid mediated stereosclective hydrophosphonylation of α-amino aldehydes

Tsutomu Yokomatsu, Takehiro Yamagishi, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 338 KB

english, 1993

59

Enantioselectivity for hydrophosphonylation of aromatic aldehydes catalyzed by lanthanum binaphthol complex. Remarkable electronic effect of aromatic substituents

Tsutomu Yokomatsu, Takehiro Yamagishi, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 122 KB

english, 1993

60

Enantioselective hydrophosphonylation of aromatic aldehydes catalyzed by chiral titanium alkoxides

Tsutomu Yokomatsu, Takehiro Yamagishi, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 278 KB

english, 1993

61

Synthesis and biological evaluation of α,α-difluorobenzylphosphonic acid derivatives as small molecular inhibitors of protein-tyrosine phosphatase 1B

Tsutomu Yokomatsu, Tetsuo Murano, Ikuko Umesue, Shinji Soeda, Hiroshi Shimeno, Shiroshi Shibuya

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 318 KB

english, 1999

62

Synthesis and biological evaluation of 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acids possessing a N9-purinylmethyl functional group at the ring. A new class of inhibitors for purine nucleoside phosphorylases

Tsutomu Yokomatsu, Yoshinobu Hayakawa, Kenji Suemune, Taro Kihara, Shinji Soeda, Hiroshi Shimeno, Shiroshi Shibuya

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 275 KB

english, 1999

63

Synthesis and evaluation of multisubstrate analogue inhibitors of purine nucleoside phosphorylases

Tsutomu Yokomatsu, Yoshinobu Hayakawa, Taro Kihara, Satoru Koyanagi, Shinji Soeda, Hiroshi Shimeno, Shiroshi Shibuya

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

64

Synthesis of 1,1-difluoro-5-(1H-9-purinyl)-2-pentenylphosphonic acids and the related methano analogues. Remarkable effect of the nucleobases and the cyclopropane rings on inhibitory activity toward purine nucleoside phosphorylase

Tsutomu Yokomatsu, Hiroshi Abe, Mutsumi Sato, Kenji Suemune, Taro Kihara, Shinji Soeda, Hiroshi Shimeno, Shiroshi Shibuya

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 1.09 MB

english, 1998

65

Enantioselective synthesis of threo-α,β-dihydroxyphosphonates by asymmetric dihydroxylation of vinylphosphonates. An application to the stereocontrolled synthesis of (4S,5S)-4-diethylphosphono-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolane

Tsutomu Yokomatsu, Yoshinori Yoshida, Kenji Suemune, Takehiro Yamagishi, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 228 KB

english, 1995

66

Enantioselective Synthesis of (−)-desoxoprosopinine by radical cyclization

Yoko Yuasa, Jun Ando, Shiroshi Shibuya

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 126 KB

english, 1995

67

Stereoselective Reduction of Cyclopropylalkaones Possessing a Difluoromethylenephosphonate Group at the Ring: Application to Stereoselective Synthesis of Novel Cyclopropane Nucleotide Analogues

Tsutomu Yokomatsu, Takehiro Yamagishi, Kenji Suemune, Hiroshi Abe, Taro Kihara, Shinji Soeda, Hiroshi Shimeno, Shiroshi Shibuya

Journal:

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

68

Radical-mediated furanose ring reconstruction from 2′,3′-seco-uridine

Hiroki Kumamoto, Junko Ogamino, Hiromichi Tanaka, Hisaki Suzuki, Kazuhiro Haraguchi, Tadashi Miyasaka, Tsutomu Yokomatsu, Shiroshi Shibuya

Journal:

Year:

2001

Language:

english

File:

PDF, 285 KB

english, 2001

69

Total syntheses of (+)-cularimine and (+)-cularine

Tetsuji Kametani, Shiroshi Shibuya

Journal:

Tetrahedron Letters

Year:

1965

Language:

english

File:

PDF, 115 KB

english, 1965

70

Synthesis of non-competitive inhibitors of Sphingomyelinases with significant activity

Tsutomu Yokomatsu, Tetsuo Murano, Takeshi Akiyama, Junichi Koizumi, Shiroshi Shibuya, Yoshiaki Tsuji, Shinji Soeda, Hiroshi Shimeno

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

71

Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice

Akira Sakata, Takashi Ochiai, Hiroshi Shimeno, Sadao Hikishima, Tsutomu Yokomatsu, Shiroshi Shibuya, Akihisa Toda, Reiko Eyanagi, Shinji Soeda

Journal:

Year:

2007

Language:

english

File:

PDF, 788 KB

english, 2007

72

Studies on the syntheses of heterocyclic compounds. CLXXIV. An approach to the synthesis of oxyacanthine and berbamine

Tetsuji Kametani, Hideo Lida, Shinzo Kano, Sadao Tanaka, Keiichiro Fukumoto, Shiroshi Shibuya, Haruhiko Yagi

Journal:

Journal of Heterocyclic Chemistry

Year:

1967

Language:

english

File:

PDF, 719 KB

english, 1967

73

Studies on the syntheses of azole derivatives. Part VII. Syntheses of 1 -phenyl-Δ2-1,2,4-triazolin-5-one derivatives [studies on the syntheses of heteroeyclic compounds. CD XI]

Tetsuji Kamatani, Shiroshi Shibuya, Mamhisa Shio

Journal:

Journal of Heterocyclic Chemistry

Year:

1971

File:

PDF, 219 KB

1971

74

Studies on the syntheses of heterocyclie compounds. Part DXXVII.. the absolute configuration of 1,2,3,4-tetrahydro-1-phenylisoquinolines

Tetsuji Kametani, Shiroshi Shibuya, Hideo Sugi, Keiichiro Fukumoto

Journal:

Journal of Heterocyclic Chemistry

Year:

1973

File:

PDF, 133 KB

1973

75

Synthesis of quinoxaline derivatives through condensation of 1,2-diaminobenzenes with β-keto sulfoxides

Shinzo Kano, Shiroshi Shibuya, Yoko Yuasa

Journal:

Journal of Heterocyclic Chemistry

Year:

1980

File:

PDF, 200 KB

1980

76

Formation of pyrrole derivatives through aminolysis of 2-azetidinone derivatives

Shinzo Kano, Shiroshi Shibuya, Tsutomu Ebata

Journal:

Journal of Heterocyclic Chemistry

Year:

1981

Language:

english

File:

PDF, 218 KB

english, 1981

77

Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice

Akira Sakata, Kazuya Yasuda, Takashi Ochiai, Hiroshi Shimeno, Sadao Hikishima, Tsutomu Yokomatsu, Shiroshi Shibuya, Shinji Soeda

Journal:

Cellular Immunology

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

78

Convenient Synthesis of Cyclopropylalkanol Derivatives Possessing a Difluoromethylenephosphonate Group at the Ring

Yokomatsu, Tsutomu, Abe, Hiroshi, Yamagishi, Takehiro, Suemune, Kenji, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

79

Formation of 2,3-dihydro-4(1H)-quinolones and related compounds via Fries-type acid-catalysed rearrangement of 1-arylazetidin-2-ones

Kano, Shinto, Ebata, Tsutomu, Shibuya, Shiroshi

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1980

Language:

english

File:

PDF, 780 KB

english, 1980

80

Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress

Shinji Soeda, Yoshiaki Tsuji, Takashi Ochiai, Ken-ichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara, Tsutomu Yokomatsu, Tetsuo Murano, Shiroshi Shibuya, Hiroshi Shimeno

Journal:

Neurochemistry International

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

81

An attempt to promote neo-vascularization by employing a newly synthesized inhibitor of protein tyrosine phosphatase

Shinji Soeda, Takuji Shimada, Satoru Koyanagi, Tsutomu Yokomatsu, Tetsuo Murano, Shiroshi Shibuya, Hiroshi Shimeno

Journal:

Year:

2002

Language:

english

File:

PDF, 354 KB

english, 2002

82

Diels–Alder cycloaddition of novel buta-1,3-diene derivatives possessing a (diethoxyphosphinoyl)difluoromethyl unit

Yokomatsu, Tsutomu, Katayama, Satoru, Shibuya, Shiroshi

Journal:

Chemical Communications

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

83

New synthetic design for formation of carbon-carbon triple bonds

Kano, Shinzo, Yokomatsu, Tsutomu, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1978

Language:

english

File:

PDF, 281 KB

english, 1978

84

Highly diastereoselective route to trans-5-substituted 2-hydroxymethylpyrrolidine derivatives by radical cyclisation

Yuasa, Yoko, Ando, Jun, Shibuya, Shiroshi

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1996

Language:

english

File:

PDF, 1.38 MB

english, 1996

85

Synthesis of Aryldifluoromethylphosphonothioic Acids from O , O -Diethyl Aryldifluoromethylphosphonothioates

Yokomatsu, Tsutomu, Takechi, Hiroaki, Murano, Tetsuo, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

86

Simple and Efficient Method for Preparation of Conformationally Constrained Aminomethylene gem-Diphosphonate Derivatives via Beckmann Rearrangement

Yokomatsu, Tsutomu, Yoshida, Yoshinori, Nakabayashi, Nobuko, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 306 KB

english, 1994

87

Synthetic application of azetidin-2-ones to a synthesis of furan derivatives

Kano, Shinzo, Shibuya, Shiroshi, Ebata, Tsutomu

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1982

Language:

english

File:

PDF, 442 KB

english, 1982

88

New synthesis of the antitumor 6H-pyrido[4,3-b]carbazole alkaloid ellipticine

Kano, Shinzo, Sugino, Eiichi, Shibuya, Shiroshi, Hibino, Satoshi

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 476 KB

english, 1981

89

[Studies in Natural Products Chemistry] Stereoselective Synthesis Volume 12 || Stereoselective Synthesis of Natural Products via Cationic and Radical Intermediates

Shibuya, Shiroshi

Year:

1993

Language:

english

File:

PDF, 1.90 MB

english, 1993

90

Enantioselective synthesis of α-hydroxyphosphonates through asymmetric Pudovik reactions with chiral lanthanoid and titanium alkoxides

Yokomatsu, Tsutomu, Yamagishi, Takehiro, Shibuya, Shiroshi

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1997

Language:

english

File:

PDF, 559 KB

english, 1997

91

Resolution of Racemic Rhododendrol by Lipase-Catalyzed Enantioselective Acetylation

Yuasa, Yoshifumi, Shibuya, Shiroshi, Yuasa, Yoko

Journal:

Synthetic Communications

Year:

2003

Language:

english

File:

PDF, 192 KB

english, 2003

92

Effect of a-strain on a synthesis of cis-fused 4a-aryloctahydro-1H-cyclopenta[c]pyridine derivatives through tandem radical cyclisation of an ?-acylamino?polyene system

Kano, Shinzo, Yuasa, Yoko, Yokomatsu, Tsutomu, Asami, Kenji, Shibuya, Shiroshi

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1986

Language:

english

File:

PDF, 206 KB

english, 1986

93

Synthesis of (α,α-Difluoroallyl)phosphonates from Alkenyl Halides or Acetylenes

Yokomatsu, Tsutomu, Suemune, Kenji, Murano, Tetsuo, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 203 KB

english, 1996

94

Correction. Polyene Cyclization Strategy in the Stereospecific Synthesis of B/C-trans-Morphinan. A Total Synthesis of (±)-O-Methylpallidinine

Kano, Shinzo, Yokomatsu, Tsutomu, Nemoto, Hajime, Shibuya, Shiroshi

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 99 KB

english, 1987

95

Synthesis of 6-thiaellipticine and related compounds via heterocyclic o-quinodimethane intermediates

Kano, Shinzo, Mochizuki, Naoki, Hibino, Satoshi, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1982

Language:

english

File:

PDF, 568 KB

english, 1982

96

New diastereoselective synthesis of oxazolidin-2-ones through carbon-carbon bond formation on cyclic carbamoyloxy radicals

Kano, Shinzo, Yokomatsu, Tsutomu, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 341 KB

english, 1989

97

A synthesis of oxazolo[4,3-a]isoquinoline and related compounds through intramolecular arylation of .alpha.-oxaacyliminium ions

Kano, Shinzo, Yuasa, Yoko, Yokomatsu, Tsutomu, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1983

Language:

english

File:

PDF, 376 KB

english, 1983

98

Highly stereocontrolled synthesis of the four individual stereoisomers of statine

Kano, Shinzo, Yuasa, Yoko, Yokomatsu, Tsutomu, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 622 KB

english, 1988

99

Tumor inhibitors. LXXXVI. Structural elucidation of novel tumor-inhibitory sesquiterpene lactones from Eupatorium cuneifolium

Kupchan, S. Morris, Maruyama, Masao, Hemingway, Richard J., Hemingway, Jane C., Shibuya, Shiroshi, Fujita, Tetsuro

Journal:

Journal of Organic Chemistry

Year:

1973

Language:

english

File:

PDF, 1.18 MB

english, 1973

100

Stereoselective synthesis of 7-thia-16-oxa-14.beta.-estrones

Kano, Shinzo, Tanaka, Kohtaro, Hibino, Satoshi, Shibuya, Shiroshi

Journal:

Journal of Organic Chemistry

Year:

1979

Language:

english

File:

PDF, 371 KB

english, 1979