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51

Allosteric inhibition of rat neuronal nitric-oxide synthase caused by interference with the binding of calmodulin to the enzyme

Koji Ohashi, Takeshi Yamazaki, Shigeyuki Kitamura, Shigeru Ohta, Shunsuke Izumi, Shiro Kominami

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2007

Language:

english

File:

PDF, 400 KB

english, 2007

52

Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo

Kazumi Sugihara, Shigeyuki Kitamura, Tsuyoshi Yamada, Takashige Okayama, Shigeru Ohta, Keisuke Yamashita, Mineo Yasuda, Yoshiaki Fujii-Kuriyama, Ken'ich Saeki, Saburo Matsui, Tomonari Matsuda

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 375 KB

english, 2004

53

Inhibitory effect of organotin compounds on rat neuronal nitric oxide synthase through interaction with calmodulin

Koji Ohashi, Shiro Kominami, Takeshi Yamazaki, Shigeru Ohta, Shigeyuki Kitamura

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

54

Improved gene expression in resting macrophages using an oligopeptide derived from Vpr of human immunodeficiency virus type-1

Izuru Mizoguchi, Yoshihiro Ooe, Shigeki Hoshino, Mari Shimura, Tadashi Kasahara, Shigeyuki Kano, Toshiko Ohta, Fumimaro Takaku, Yasuhide Nakayama, Yukihito Ishizaka

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

55

Enhanced antioxidant defense due to extracellular catalase activity in Syrian hamster during arousal from hibernation

Hitomi Ohta, Iwao Okamoto, Toshiharu Hanaya, Shigeyuki Arai, Tsunetaka Ohta, Shigeharu Fukuda

Journal:

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

Year:

2006

Language:

english

File:

PDF, 307 KB

english, 2006

56

In vivo function of the 5′ flanking region of mouse estrogen receptor β gene

Nariaki Fujimoto, Osamu Nakajima, Shigeyuki Kitamura, Shigeru Ohta

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 429 KB

english, 2007

57

Production of superoxide radical in reductive metabolism of a synthetic food-coloring agent, indigocarmine, and related compounds

Yoichi Kohno, Shigeyuki Kitamura, Tsuyoshi Yamada, Kazumi Sugihara, Shigeru Ohta

Journal:

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

58

Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer

Balasundaram Padmanabhan, Kit I. Tong, Tsutomu Ohta, Yoshihiro Nakamura, Maria Scharlock, Makiko Ohtsuji, Moon-Il Kang, Akira Kobayashi, Shigeyuki Yokoyama, Masayuki Yamamoto

Journal:

Year:

2006

Language:

english

File:

PDF, 858 KB

english, 2006

59

Light-driven control of receptor tyrosine kinase signaling

Masayuki Isa, Yusaku Ohta, Shigeyuki Namiki, Kenzo Hirose

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

60

Anti-neurodegenerative activity of photosensitizing dyes (1): The neurotrophic effects of photosensitizing dye and potential mechanisms of action

Hitomi Ohta, Kenji Akita, Shigeyuki Arai, Tsunetaka Ohta, Toshio Kawata, Shigeharu Fukuda

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

61

Anti-neurodegenerative activity of photosensitizing dyes (3): The effect on a hereditary cerebellar ataxia

Kenji Akita, Hitomi Ohta, Shigeyuki Arai, Tsunetaka Ohta, Shigeharu Fukuda

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

62

Anti-neurodegenerative activity of photosensitizing dyes (2): The effect on transient focal cerebral ischemia in rats

Satomi Miyata, Hitomi Ohta, Kenji Akita, Shigeyuki Arai, Tsunetaka Ohta, Shigeharu Fukuda

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

63

Near-infrared luminescent bis-squaraine dyes linked by a thiophene or pyrene spacer for noncovalent protein labeling

Hiroyuki Nakazumi, Taishi Ohta, Hiroyuki Etoh, Takaaki Uno, Christa L. Colyer, Yutaka Hyodo, Shigeyuki Yagi

Journal:

Synthetic Metals

Year:

2005

File:

PDF, 618 KB

2005

64

An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide

Kana Matsubara, Seigo Sanoh, Shigeru Ohta, Shigeyuki Kitamura, Kazumi Sugihara, Nariaki Fujimoto

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 390 KB

english, 2012

65

Expression and purification of recombinant human histones

Yoshinori Tanaka, Maki Tawaramoto-Sasanuma, Shinichi Kawaguchi, Tsutomu Ohta, Kinya Yoda, Hitoshi Kurumizaka, Shigeyuki Yokoyama

Journal:

Year:

2004

Language:

english

File:

PDF, 975 KB

english, 2004

66

Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A

Shigeyuki Kitamura, Norimasa Jinno, Shigeru Ohta, Hiroaki Kuroki, Nariaki Fujimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

67

Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes

Takashi Fujimoto, Shigeyuki Kitamura, Seigo Sanoh, Kazumi Sugihara, Shin’ichi Yoshihara, Nariaki Fujimoto, Shigeru Ohta

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

68

Bone resorption versus estrogen loss following oophorectomy and menopause

Hiroaki Ohta, Kazuya Makita, Shigeyuki Komukai, Shiro Nozawa

Journal:

Year:

2002

Language:

english

File:

PDF, 221 KB

english, 2002

69

Effect of a HMG-CoA reductase inhibitor combined with hormone replacement therapy on lipid metabolism in Japanese women with hypoestrogenic lipidemia: a multicenter double-blind controlled prospective study

Hiroaki Ohta, Shigeyuki Komukai, Itaru Sugimoto, Takahisa Fuyuki, Kazuya Makita, Kiyoshi Takamatsu, Fumi Horiguchi, Shiro Nozawa

Journal:

Year:

1998

Language:

english

File:

PDF, 110 KB

english, 1998

70

Whole-body metabolism of the organophosphorus pesticide, fenthion, in goldfish, Carassius auratus

Shigeyuki Kitamura, Tomoko Kadota, Mayumi Yoshida, Norimasa Jinno, Shigeru Ohta

Journal:

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology

Year:

2000

Language:

english

File:

PDF, 138 KB

english, 2000

71

Cynomolgus monkey liver aldehyde oxidase: extremely high oxidase activity and an attempt at purification

Kazumi Sugihara, Yasuko Katsuma, Shigeyuki Kitamura, Shigeru Ohta, Morioki Fujitani, Hideaki Shintani

Journal:

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology

Year:

2000

Language:

english

File:

PDF, 181 KB

english, 2000

72

Strain differences of the ability to hydroxylate methotrexate in rats

Shigeyuki Kitamura, Keiko Nakatani, Kazumi Sugihara, Shigeru Ohta

Journal:

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology

Year:

1999

Language:

english

File:

PDF, 178 KB

english, 1999

73

Synthesis, in Vitro Pharmacology, Structure−Activity Relationships, and Pharmacokinetics of 3-Alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent and Selective Group II Metabotropic Glutamate Receptor Antagonists

Nakazato, Atsuro, Sakagami, Kazunari, Yasuhara, Akito, Ohta, Hiroshi, Yoshikawa, Ryoko, Itoh, Manabu, Nakamura, Masato, Chaki, Shigeyuki

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 215 KB

english, 2004

74

Design, Synthesis, and Pharmacological Activity of Nonallergenic Pyrazolone-Type Antipyretic Analgesics

Uramaru, Naoto, Shigematsu, Hidenari, Toda, Akihisa, Eyanagi, Reiko, Kitamura, Shigeyuki, Ohta, Shigeru

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.59 MB

english, 2010

75

Methylation of DNA in the chloroplasts and amyloplasts of the pea, Pisum sativum

Niji Ohta, Naoki Sato, Shigeyuki Kawano, Tsuneyoshi Kuroiwa

Journal:

Year:

1991

Language:

english

File:

PDF, 933 KB

english, 1991

76

Growth Dynamics of Domains in Ternary Fluid Vesicles

Yanagisawa, Miho, Imai, Masayuki, Masui, Tomomi, Komura, Shigeyuki, Ohta, Takao

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 670 KB

english, 2007

77

Ultraviolet-photoproduct of acetaminophen: Structure determination and evaluation of ecotoxicological effect

Kawabata, Kohei, Sugihara, Kazumi, Sanoh, Seigo, Kitamura, Shigeyuki, Ohta, Shigeru

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

2012

Language:

english

File:

PDF, 548 KB

english, 2012

78

Comparative study of the hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by microsomes of various rat and human tissues

Ozaki, Hitomi, Sugihara, Kazumi, Watanabe, Yoko, Fujino, Chieri, Uramaru, Naoto, Sone, Tomomichi, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

79

Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes

Tanoue, Chiaki, Sugihara, Kazumi, Uramaru, Naoto, Tayama, Yoshitaka, Watanabe, Yoko, Horie, Toru, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 350 KB

english, 2013

80

2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes

Kamikyouden, Nagisa, Sugihara, Kazumi, Watanabe, Yoko, Uramaru, Naoto, Murahashi, Tsuyoshi, Kuroyanagi, Masanori, Sanoh, Seigo, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 758 KB

english, 2013

81

Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor

Watanabe, Yoko, Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Food and Chemical Toxicology

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

82

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Dynamical Aspects of Two-Dimensional Soft Matter

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 2.38 MB

english, 2012

83

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Actively Twisted Polymers and Filaments in Biology

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

84

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Morphology and Rheology of Immiscible Polymer Blends in Electric and Shear Flow Fields

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 2.15 MB

english, 2012

85

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Rheo-Dielectric Behavior of Soft Matters

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

86

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Hydrodynamic Effects in Multicomponent Fluid Membranes

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

87

[Series in Soft Condensed Matter] Non-Equilibrium Soft Matter Physics Volume 4 || Dynamics of Deformable Self-Propelled Particles: Relations with Cell Migration

Komura, Shigeyuki, Ohta, Takao

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

88

Design, Synthesis, Structure−Activity Relationships, and Biological Characterization of Novel Arylalkoxyphenylalkylamine σ Ligands as Potential Antipsychotic Drugs

Nakazato, Atsuro, Ohta, Kohmei, Sekiguchi, Yoshinori, Okuyama, Shigeru, Chaki, Shigeyuki, Kawashima, Yutaka, Hatayama, Katsuo

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 274 KB

english, 1999

89

Case report

Kikuchi, Kenji, Imura, Shigeyuki, Miyakawa, Kazunori, Kubota, Misao, Ohta, Eiji

Journal:

Clinical Immunology Newsletter

Year:

1988

Language:

english

File:

PDF, 207 KB

english, 1988

90

NK-4, a photosensitizing cyanine dye, prevented beta-amyloid-induced cognitive impairment in a transgenic mouse model of Alzheimer's disease

Ohta, Hitomi, Akita, Kenji, Arai, Shigeyuki, Ohta, Tsunetaka, Kawata, Toshio, Fukuda, Shigeharu

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

91

Amygdala kindling induces nestin expression in the leptomeninges of the neocortex

Ninomiya, Shogo, Esumi, Shigeyuki, Ohta, Kunimasa, Fukuda, Takaichi, Ito, Tetsufumi, Imayoshi, Itaru, Kageyama, Ryoichiro, Ikeda, Toshio, Itohara, Shigeyoshi, Tamamaki, Nobuaki

Journal:

Neuroscience Research

Year:

2013

Language:

english

File:

PDF, 2.99 MB

english, 2013

92

In vitro metabolism of cis- and trans-permethrin by rat liver microsomes, and its effect on estrogenic and anti-androgenic activities

Tange, Satoko, Fujimoto, Nariaki, Uramaru, Naoto, Sugihara, Kazumi, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Environmental Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

93

RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists

Kakuta, Hiroki, Yakushiji, Nobumasa, Shinozaki, Ryosuke, Ohsawa, Fuminori, Yamada, Shoya, Ohta, Yui, Kawata, Kohei, Nakayama, Mariko, Hagaya, Manabu, Fujiwara, Chisa, Makishima, Makoto, Uno, Shigeyuki

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

94

Antiandrogenic Activity and Metabolism of the Organophosphorus Pesticide Fenthion and Related Compounds

Shigeyuki Kitamura, Tomoharu Suzuki, Shigeru Ohta and Nariaki Fujimoto

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 2.11 MB

english, 2003

95

Estrogenic Activity of Styrene Oligomers after Metabolic Activation by Rat Liver Microsomes

Shigeyuki Kitamura, Motoko Ohmegi, Seigo Sanoh, Kazumi Sugihara, Shin'ichi Yoshihara, Nariaki Fujimoto and Shigeru Ohta

Journal:

Environmental Health Perspectives

Year:

2003

Language:

english

File:

PDF, 1.90 MB

english, 2003

96

Conformational equilibrium of an enzyme catalytic site in the allosteric transition

Koide, Shohei, Yokoyama, Shigeyuki, Matsuzawa, Hiroshi, Miyazawa, Tatsuo, Ohta, Takahisa

Journal:

Year:

1992

Language:

english

File:

PDF, 922 KB

english, 1992

97

Polarized Absorption Spectra and Molecular Orientation of Some Cyanine Dyes in Langmuir-Blodgett Monolayer Films

Ohta, Nobuhiro, Matsunami, Shigeyuki, Okazaki, Sigetoshi, Yamazaki, Iwao

Journal:

Year:

1994

Language:

english

File:

PDF, 412 KB

english, 1994

98

Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy

Sanoh, Seigo, Tayama, Yoshitaka, Sugihara, Kazumi, Kitamura, Shigeyuki, Ohta, Shigeru

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

99

SUPPRESSED NNA1 GENE EXPRESSION IN THE BRAIN OF ATAXIC SYRIAN HAMSTERS

Akita, Kenji, Arai, Shigeyuki, Ohta, Tsunetaka, Hanaya, Toshiharu, Fukuda, Shigeharu

Journal:

Journal of Neurogenetics

Year:

2007

Language:

english

File:

PDF, 1.39 MB

english, 2007

100

Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity

Watanabe, Yoko, Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sanoh, Seigo, Sugihara, Kazumi, Kitamura, Shigeyuki, Ohta, Shigeru

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

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