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1

Quinolinyl Pyrimidines: Potent Inhibitors of NDH-2 as a Novel Class of Anti-TB Agents

Shirude, Pravin S., Paul, Beena, Roy Choudhury, Nilanjana, Kedari, Chaitanya, Bandodkar, Balachandra, Ugarkar, Bheemarao G.

Journal:

ACS Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 674 KB

english, 2012

2

Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo

Shirude, Pravin S., Shandil, Radha, Sadler, Claire, Naik, Maruti, Hosagrahara, Vinayak, Hameed, Shahul, Shinde, Vikas, Bathula, Chandramohan, Humnabadkar, Vaishali, Kumar, Naveen, Reddy, Jitendar, Pan

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 870 KB

english, 2013

3

Diarylethynyl Amides That Recognize the Parallel Conformation of Genomic Promoter DNA G-Quadruplexes

Dash, Jyotirmayee, Shirude, Pravin S., Hsu, Shang-Te Danny, Balasubramanian, Shankar

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 814 KB

english, 2008

4

[Annual Reports in Medicinal Chemistry] Volume 49 || Advancement of Cell Wall Inhibitors in Mycobacterium tuberculosis*Present address: Sai Life Sciences Ltd, Pune, India.

Shirude, Pravin S.

Year:

2014

Language:

english

File:

PDF, 699 KB

english, 2014

5

Synthesis of Bis-indole Carboxamides as G-Quadruplex Stabilizing and Inducing Ligands

Dr. Jyotirmayee Dash, Rabindra Nath Das, Nagaratna Hegde, Dr. G. Dan Pantoş, Pravin S. Shirude, Prof.Dr. Shankar Balasubramanian

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 964 KB

english, 2012

6

BisPNA Targeting to DNA: Effect of Neutral Loop on DNA Duplex Strand Invasion by aepPNA-N7G/aepPNA-C Substituted Peptide Nucleic Acids

Pravin S. Shirude, Vaijayanti A. Kumar, Krishna N. Ganesh

Journal:

European Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 217 KB

english, 2005

7

Chimeric peptide nucleic acids incorporating (2S,5R)-aminoethyl pipecolyl units: synthesis and DNA binding studies

Pravin S. Shirude, Vaijayanti A. Kumar, Krishna N. Ganesh

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

8

(2S,5R/2R,5S)-Aminoethylpipecolyl aepip-aegPNA chimera: synthesis and duplex/triplex stability

Pravin S. Shirude, Vaijayanti A. Kumar, Krishna N. Ganesh

Journal:

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004

9

Single molecule conformational analysis of DNA G-quadruplexes

Pravin S. Shirude, Shankar Balasubramanian

Journal:

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

10

G-quadruplex recognition by bis-indole carboxamides

Dash, Jyotirmayee, Shirude, Pravin S., Balasubramanian, Shankar

Journal:

Chemical Communications

Year:

2008

Language:

english

File:

PDF, 618 KB

english, 2008

11

Rigid cyanine dye nucleic acid labels

Fegan, Adrian, Shirude, Pravin S., Balasubramanian, Shankar

Journal:

Chemical Communications

Year:

2008

Language:

english

File:

PDF, 602 KB

english, 2008

12

Synthesis of Aqueous Au Core−Ag Shell Nanoparticles Using Tyrosine as a pH-Dependent Reducing Agent and Assembling Phase-Transferred Silver Nanoparticles at the Air−Water Interface

Selvakannan, PR., Swami, Anita, Srisathiyanarayanan, D., Shirude, Pravin S., Pasricha, Renu, Mandale, Anandrao B., Sastry, Murali

Journal:

Year:

2004

Language:

english

File:

PDF, 599 KB

english, 2004

13

Challenges and opportunities in tuberculosis drug discovery: an industry perspective

Shirude, Pravin S, Ramachandran, Sreekanth, Hosagrahara, Vinayak

Journal:

Future Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 696 KB

english, 2013

14

Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis

Shirude, Pravin S., Madhavapeddi, Prashanti, Tucker, Julie A., Murugan, Kannan, Patil, Vikas, Basavarajappa, Halesha, Raichurkar, Anandkumar V., Humnabadkar, Vaishali, Hussein, Syeed, Sharma, Sreevall

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

15

Macrocyclic and Helical Oligoamides as a New Class of G-Quadruplex Ligands

Shirude, Pravin S., Gillies, Elizabeth R., Ladame, Sylvain, Godde, Frédéric, Shin-ya, Kazuo, Huc, Ivan, Balasubramanian, Shankar

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

16

Oxazole-Based Peptide Macrocycles: A New Class of G-Quadruplex Binding Ligands

Jantos, Katja, Rodriguez, Raphaël, Ladame, Sylvain, Shirude, Pravin S., Balasubramanian, Shankar

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 50 KB

english, 2006

17

Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition

Waller, Zoë A. E., Shirude, Pravin S., Rodriguez, Raphaël, Balasubramanian, Shankar

Journal:

Chemical Communications

Year:

2008

Language:

english

File:

PDF, 565 KB

english, 2008

18

Trisubstituted Isoalloxazines as a New Class of G-Quadruplex Binding Ligands: Small Molecule Regulation of c-kit Oncogene Expression

Bejugam, Mallesham, Sewitz, Sven, Shirude, Pravin S., Rodriguez, Raphaël, Shahid, Ramla, Balasubramanian, Shankar

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 64 KB

english, 2007

19

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 47 Volume 47 || Nonfluoroquinolone-Based Inhibitors of Mycobacterial Type II Topoisomerase as Potential Therapeutic Agents for TB

Shirude, Pravin S.

Year:

2012

Language:

english

File:

PDF, 335 KB

english, 2012

20

Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis

Shirude, Pravin S., Madhavapeddi, Prashanti, Naik, Maruti, Murugan, Kannan, Shinde, Vikas, Nandishaiah, Radha, Bhat, Jyothi, Kumar, Anupriya, Hameed, Shahul, Holdgate, Geoffrey, Davies, Gareth, McMike

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.87 MB

english, 2013

21

Discovery of Pyrazolopyridones as a Novel Class of Noncovalent DprE1 Inhibitor with Potent Anti-Mycobacterial Activity

Panda, Manoranjan, Ramachandran, Sreekanth, Ramachandran, Vasanthi, Shirude, Pravin S., Humnabadkar, Vaishali, Nagalapur, Kavitha, Sharma, Sreevalli, Kaur, Parvinder, Guptha, Supreeth, Narayan, Ashwin

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.57 MB

english, 2014

22

Lead Optimization of 1,4-Azaindoles as Antimycobacterial Agents

Shirude, Pravin S., Shandil, Radha K., Manjunatha, M. R., Sadler, Claire, Panda, Manoranjan, Panduga, Vijender, Reddy, Jitendar, Saralaya, Ramanatha, Nanduri, Robert, Ambady, Anisha, Ravishankar, Sudh

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

23

Alkylidene Oxapenem β-Lactamase Inhibitors Revisited: Potent Broad Spectrum Activity but New Stability Challenges

Miller, Matthew D., Kale, Manoj, Reddy, Kishore, Tentarelli, Sharon, Zambrowski, Mark, Zhang, Minli, Palmer, Tiffany, Breen, John, Lahiri, Sushmita, Shirude, Pravin S., Verheijen, Jeroen C.

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

24

G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic

Jena, Prakrit V., Shirude, Pravin S., Okumus, Burak, Laxmi-Reddy, Katta, Godde, Frédéric, Huc, Ivan, Balasubramanian, Shankar, Ha, Taekjip

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 284 KB

english, 2009

25

Isothermal Titration Calorimetry Studies on the Binding of Amino Acids to Gold Nanoparticles

Joshi, Hrushikesh, Shirude, Pravin S., Bansal, Vipul, Ganesh, K. N., Sastry, Murali

Journal:

Journal of Physical Chemistry B

Year:

2004

Language:

english

File:

PDF, 253 KB

english, 2004

26

Single-Molecule Conformational Analysis of G-Quadruplex Formation in the Promoter DNA Duplex of the Proto-Oncogene C-Kit

Shirude, Pravin S., Okumus, Burak, Ying, Liming, Ha, Taekjip, Balasubramanian, Shankar

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 489 KB

english, 2007

27

Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC

Shirude, Pravin S., Ying, Liming, Balasubramanian, Shankar

Journal:

Chemical Communications

Year:

2008

Language:

english

File:

PDF, 760 KB

english, 2008

28

Impact of CO 2 -solvent separators on the degradation of benzyl-2,3-dihydroxypiperidine-1-carboxylate during preparative supercritical fluid chromatographic (SFC) purification

Asokan, Kathiravan, Naidu, Harshavardhan, Madam, Ratalababu, Shaikh, Khaja Mohiuddin, Reddy, Manjunath, Kumar, Hemantha, Shirude, Pravin S., Rajendran, Muruganantham, Sarabu, Ramakanth, Wu, Dauh-Rurng

Journal:

Journal of Chromatography A

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017