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1

Fighting the War Against COVID-19 via Cell-Based Regenerative Medicine: Lessons Learned from 1918 Spanish Flu and Other Previous Pandemics

Park, You Jeong, Farooq, Jeffrey, Cho, Justin, Sadanandan, Nadia, Cozene, Blaise, Gonzales-Portillo, Bella, Saft, Madeline, Borlongan, Maximillian C., Borlongan, Mia C., Shytle, R. Douglas, Willing, A

Journal:

Stem Cell Reviews and Reports

Year:

2020

File:

PDF, 1.56 MB

2020

2

Anxiolytic effects of mecamylamine in two animal models of anxiety.

Newman, Mary B., Manresa, John J., Sanberg, Paul R., Shytle, R. Douglas

Journal:

Experimental and Clinical Psychopharmacology

Year:

2002

Language:

english

File:

PDF, 379 KB

english, 2002

3

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

Kavon Rezai-Zadeh, Gary W. Arendash, Huayan Hou, Frank Fernandez, Maren Jensen, Melissa Runfeldt, R. Douglas Shytle, Jun Tan

Journal:

Year:

2008

Language:

english

File:

PDF, 829 KB

english, 2008

4

Cocrystals of Quercetin with Improved Solubility and Oral Bioavailability

Smith, Adam J., Kavuru, Padmini, Wojtas, Lukasz, Zaworotko, Michael J., Shytle, R. Douglas

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 3.69 MB

english, 2011

5

Nicotine's oxidative and antioxidant properties in CNS

Mary B Newman, Gary W Arendash, R.Douglas Shytle, Paula C Bickford, Thomas Tighe, Paul R Sanberg

Journal:

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

6

Nutraceutical Intervention Improves Older Adults' Cognitive Functioning

Small, Brent J., Rawson, Kerri S., Martin, Christina, Eisel, Sarah L., Sanberg, Cyndy D., McEvoy, Cathy L., Sanberg, Paul R., Shytle, R. Douglas, Tan, Jun, Bickford, Paula C.

Journal:

Rejuvenation Research

Year:

2014

Language:

english

File:

PDF, 212 KB

english, 2014

7

Psychometric Properties of the Hoarding Assessment Scale in College Students

Schneider, Andrea F., Storch, Eric A., Geffken, Gary R., Lack, Caleb W., Shytle, R. Douglas

Journal:

Illness Crisis & Loss

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

8

Neuronal nicotinic receptor inhibition for treating mood disorders preliminary controlled evidence with mecamylamine

R. Douglas Shytle, Archie A. Silver, Kathy H. Sheehan, David V. Sheehan, Paul R. Sanberg

Journal:

Depression and Anxiety

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

9

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

Adam Smith, Brian Giunta, Paula C. Bickford, Michael Fountain, Jun Tan, R. Douglas Shytle

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 227 KB

english, 2010

10

Cholinergic modulation of microglial activation by α7 nicotinic receptors

R. Douglas Shytle, Takashi Mori, Kirk Townsend, Martina Vendrame, Nan Sun, Jin Zeng, Jared Ehrhart, Archie A. Silver, Paul R. Sanberg, Jun Tan

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

11

Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: Implications for HIV-associated neurocognitive disorders

Brian Giunta, Jared Ehrhart, Demian F Obregon, Lucy Lam, Lisa Le, JingJi Jin, Francisco Fernandez, Jun Tan, R Douglas Shytle

Journal:

Molecular Brain

Year:

2011

Language:

english

File:

PDF, 317 KB

english, 2011

12

Family Impact of Tourette's Syndrome

Berney J. Wilkinson, Mary B. Newman, R.Douglas Shytle, Archie A. Silver, Paul R. Sanberg, David Sheehan

Journal:

Journal of Child and Family Studies

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

13

Mecamylamine Effects on Haloperidol-Induced Catalepsy and Defecation

Sanberg, Paul R., Newman, Mary B., Manresa, John J., Potts, Sarah E., Alvarez, Franco, Cahill, David W., Shytle, R. Douglas

Journal:

International Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 544 KB

english, 2001

14

Striatal dopamine-mediated motor behavior is altered following occlusion of the middle cerebral artery

Cesario V. Borlongan, Rodrigo Martinez, R.Douglas Shytle, Thomas B. Freeman, David W. Cahill, Paul R. Sanberg

Journal:

Pharmacology Biochemistry and Behavior

Year:

1995

Language:

english

File:

PDF, 543 KB

english, 1995

15

Nicotine blocks kainic acid-induced wet dog shakes in rats

R. Douglas Shytle, Cesario V. Borlongan, Paul R. Sanberg

Journal:

Neuropsychopharmacology

Year:

1995

Language:

english

File:

PDF, 327 KB

english, 1995

16

EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-γ: Role of JAK/STAT1 signaling and implications for HIV-associated dementia

Brian Giunta, Demian Obregon, Hauyan Hou, Jin Zeng, Nan Sun, Veljko Nikolic, Jared Ehrhart, Douglas Shytle, Francisco Fernandez, Jun Tan

Journal:

Year:

2006

Language:

english

File:

PDF, 848 KB

english, 2006

17

Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism

Ellisa Parker-Athill, Deyan Luo, Antoinette Bailey, Brian Giunta, Jun Tian, R. Douglas Shytle, Tanya Murphy, Gabor Legradi, Jun Tan

Journal:

Journal of Neuroimmunology

Year:

2009

Language:

english

File:

PDF, 701 KB

english, 2009

18

Nicotinic acetylcholine receptors on NT2 precursor cells and hNT (NT2-N) neurons

Mary B Newman, Yen-Ping Kuo, Ronald J Lukas, Paul R Sanberg, R Douglas Shytle, Michael P McGrogan, Tanja Zigova

Journal:

Developmental Brain Research

Year:

2002

Language:

english

File:

PDF, 654 KB

english, 2002

19

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease β-amyloid production

Kavon Rezai-Zadeh, R. Douglas Shytle, Yun Bai, Jun Tian, Huayan Hou, Takashi Mori, Jin Zeng, Demian Obregon, Terrence Town, Jun Tan

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

20

Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice

Brian Giunta, Houyan Hou, Yuyan Zhu, Jon Salemi, Amanda Ruscin, R. Douglas Shytle, Jun Tan

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

21

Nicotine induced seizures blocked by mecamylamine and its stereoisomers

Mary B. Newman, John J. Manresa, Paul R. Sanberg, R.Douglas Shytle

Journal:

Year:

2001

Language:

english

File:

PDF, 161 KB

english, 2001

22

Treatment of Tourette's syndrome with mecamylamine

Paul R Sanberg, R Douglas Shytle, Archie A Silver

Journal:

Year:

1998

Language:

english

File:

PDF, 26 KB

english, 1998

23

Mecamylamine: new therapeutic uses and toxicity/risk profile

John M. Young, R. Douglas Shytle, Paul R. Sanberg, Tony P. George

Journal:

Clinical Therapeutics

Year:

2001

Language:

english

File:

PDF, 2.55 MB

english, 2001

24

P1-342 Cholinergic regulation of microglial activation in response to abeta

R. Douglas Shytle, Kirk Townsend, Jared Ehrhart, Nan Sun, Jin Zeng, Paul R. Sanberg, Jun Tan

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

25

Corticosterone-attenuating and anxiolytic properties of mecamylamine in the rat

Mary B. Newman, Stanley J. Nazian, Paul R. Sanberg, David M. Diamond, R.Douglas Shytle

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2001

Language:

english

File:

PDF, 541 KB

english, 2001

26

Translating laboratory discovery to the clinic: From nicotine and mecamylamine to Tourette's, depression, and beyond

Sanberg, Paul R., Vindrola-Padros, Cecilia, Shytle, R. Douglas

Journal:

Physiology & Behavior

Year:

2012

Language:

english

File:

PDF, 217 KB

english, 2012

27

Comorbid bipolar disorder in Tourette’s syndrome responds to the nicotinic receptor antagonist mecamylamine (Inversine)

R.Douglas Shytle, Archie A Silver, Paul R Sanberg

Journal:

Biological Psychiatry

Year:

2000

Language:

english

File:

PDF, 26 KB

english, 2000

28

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

Jared Ehrhart, Demian Obregon, Takashi Mori, Huayan Hou, Nan Sun, Yun Bai, Thomas Klein, Francisco Fernandez, Jun Tan, R Douglas Shytle

Journal:

Journal of Neuroinflammation

Year:

2005

Language:

english

File:

PDF, 1.30 MB

english, 2005

29

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

Kavon Rezai-Zadeh, Jared Ehrhart, Yun Bai, Paul R Sanberg, Paula Bickford, Jun Tan, R Douglas Shytle

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

30

Crystal Engineering of Green Tea Epigallocatechin-3-gallate (EGCg) Cocrystals and Pharmacokinetic Modulation in Rats

Smith, Adam J., Kavuru, Padmini, Arora, Kapildev K., Kesani, Sheshanka, Tan, Jun, Zaworotko, Michael J., Shytle, R. Douglas

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 3.29 MB

english, 2013

31

Improving Lithium Therapeutics by Crystal Engineering of Novel Ionic Cocrystals

Smith, Adam J., Kim, Seol-Hee, Duggirala, Naga K., Jin, Jingji, Wojtas, Lukasz, Ehrhart, Jared, Giunta, Brian, Tan, Jun, Zaworotko, Michael J., Shytle, R. Douglas

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 3.63 MB

english, 2013

32

Mecamylamine – a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders

Bacher, Ingrid, Wu, Becky, Shytle, Douglas R, George, Tony P

Journal:

Expert Opinion on Pharmacotherapy

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

33

ZIPRASIDONE-INDUCED OCULOGYRIC CRISIS

Ramos, Amaya E., Shytle, R. Douglas, Silver, Archie A., Sanberg, Paul R.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

2003

Language:

english

File:

PDF, 71 KB

english, 2003

34

Case Study: Long-Term Potentiation of Neuroleptics with Transdermal Nicotine in Tourette's Syndrome

SILVER, ARCHIE A., SHYTLE, R DOUGLAS, PHILIPP, MARY K., SANBERG, PAUL R.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

1996

Language:

english

File:

PDF, 4.58 MB

english, 1996

35

Multicenter, Double-Blind, Placebo-Controlled Study of Mecamylamine Monotherapy for Tourette's Disorder

SILVER, ARCHIE A., SHYTLE, R. DOUGLAS, SHEEHAN, KATHY H., SHEEHAN, DAVID V., RAMOS, AMAYA, SANBERG, PAUL R.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

2001

Language:

english

File:

PDF, 142 KB

english, 2001

36

Nutraceuticals Synergistically Promote Proliferation of Human Stem Cells

Bickford, Paula C., Tan, Jun, Shytle, R. Douglas, Sanberg, Cyndy D., El-Badri, Nagwa, Sanberg, Paul R.

Journal:

Stem Cells and Development

Year:

2006

Language:

english

File:

PDF, 196 KB

english, 2006

37

Plasma and brain pharmacokinetics of previously unexplored lithium salts

Smith, Adam J., Kim, Seol-Hee, Tan, Jun, Sneed, Kevin B., Sanberg, Paul R., Borlongan, Cesar V., Shytle, R. Douglas

Journal:

Year:

2014

Language:

english

File:

PDF, 289 KB

english, 2014

38

Mecamylamine in Tourette's Syndrome: A Two-Year Retrospective Case Study

SILVER, ARCHIE A., SHYTLE, R. DOUGLAS, SANBERG, PAUL R.

Journal:

Journal of Child and Adolescent Psychopharmacology

Year:

2000

Language:

english

File:

PDF, 1.11 MB

english, 2000

39

Oxidative Stress of Neural, Hematopoietic, and Stem Cells: Protection by Natural Compounds

Shytle, R. Douglas, Ehrhart, Jared, Tan, Jun, Vila, Jennifer, Cole, Michael, Sanberg, Cyndy D., Sanberg, Paul R., Bickford, Paula C.

Journal:

Rejuvenation Research

Year:

2007

Language:

english

File:

PDF, 2.81 MB

english, 2007

40

Physical Stability Enhancement and Pharmacokinetics of a Lithium Ionic Cocrystal with Glucose

Duggirala, Naga Kiran, Smith, Adam J., Wojtas, Łukasz, Shytle, R. Douglas, Zaworotko, Michael J.

Journal:

Crystal Growth & Design

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

41

BOOK AND MATERIAL REVIEWS: "Pediatric Psychopharmacology: Combining Medical and Psychosocial Interventions"

Wilkinson, Berney J., Shytle, R. Douglas

Journal:

Journal of Educational and Psychological Consultation

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

42

Nutraceutical intervention reverses the negative effects of blood from aged rats on stem cells

P. C. Bickford, Y. Kaneko, B. Grimmig, C. Pappas, B. Small, C. D. Sanberg, P. R. Sanberg, J. Tan, R. Douglas Shytle

Journal:

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

43

A Pilot Controlled Trial of Transdermal Nicotine in the Treatment of Attention Deficit Hyperactivity Disorder

Shytle, R. Douglas, Silver, Archie A., Wilkinson, Berney J., Sanberg, Paul R.

Journal:

The World Journal of Biological Psychiatry

Year:

2002

Language:

english

File:

PDF, 735 KB

english, 2002

44

Humoral factors in ALS patients during disease progression

Ehrhart, Jared, Smith, Adam J., Kuzmin-Nichols, Nicole, Zesiewicz, Theresa A., Jahan, Israt, Shytle, R. Douglas, Kim, Seol-Hee, Sanberg, Cyndy D., Vu, Tuan H., Gooch, Clifton L., Sanberg, Paul R., Gar

Journal:

Journal of Neuroinflammation

Year:

2015

Language:

english

File:

PDF, 717 KB

english, 2015

45

Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer’s Transgenic Mice

Shytle, R. Douglas, Tan, Jun, C. Bickford, Paula, Rezai-zadeh, Kavon, Hou, L, Zeng, Jin, Sanberg, Paul R., Sanberg, Cyndy D., S. Alberte, Randall, C. Fink, Ryan, Roschek Jr, Bill

Journal:

Current Alzheimer Research

Year:

2012

Language:

english

File:

PDF, 413 KB

english, 2012

46

Addressing potential role of magnesium dyshomeostasis to improve treatment efficacy for epilepsy: A reexamination of the literature

Osborn, Katie E., Shytle, R. Douglas, Frontera, Alfred T., Soble, Jason R., Schoenberg, Mike R.

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 163 KB

english, 2016

47

Nicotinic Antagonist Augmentation of Selective Serotonin Reuptake Inhibitor-Refractory Major Depressive Disorder

George, Tony P., Sacco, Kristi A., Vessicchio, Jennifer C., Weinberger, Andrea H., Shytle, R. Douglas

Journal:

Journal of Clinical Psychopharmacology

Year:

2008

Language:

english

File:

PDF, 115 KB

english, 2008

48

Potential new complication in drug therapy development for amyotrophic lateral sclerosis

Garbuzova-Davis, Svitlana, Thomson, Avery, Kurien, Crupa, Shytle, R. Douglas, Sanberg, Paul R.

Journal:

Expert Review of Neurotherapeutics

Year:

2016

Language:

english

File:

PDF, 952 KB

english, 2016

49

Anxiolytic effects of mecamylamine in two animal models of anxiety.

Newman, Mary B., Manresa, John J., Sanberg, Paul R., Shytle, R. Douglas

Journal:

Experimental and Clinical Psychopharmacology

Year:

2002

Language:

english

File:

PDF, 628 KB

english, 2002

50

Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice

Sawmiller, Darrell, Habib, Ahsan, Li, Song, Darlington, Donna, Hou, Huayan, Tian, Jun, Shytle, R. Douglas, Smith, Adam, Giunta, Brian, Mori, Takashi, Tan, Jun

Journal:

Journal of Neuroimmunology

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016