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51

Advances in the molecular dissection of inflammatory bowel disease

Katherine Anne Siminovitch

Journal:

Seminars in Immunology

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

52

W4R variant in CSRP3 encoding muscle LIM protein in a patient with hypertrophic cardiomyopathy

Bill Newman, David Cescon, Anna Woo, Harry Rakowski, Maria J. Erikkson, Michael Sole, E. Douglas Wigle, Katherine A. Siminovitch

Journal:

Molecular Genetics and Metabolism

Year:

2005

Language:

english

File:

PDF, 93 KB

english, 2005

53

WASP Recruitment to the T Cell:APC Contact Site Occurs Independently of Cdc42 Activation

Judy L Cannon, Christine M Labno, Gerra Bosco, Abhinav Seth, Mary H.K McGavin, Katherine A Siminovitch, Michael K Rosen, Janis K Burkhardt

Journal:

Year:

2001

Language:

english

File:

PDF, 437 KB

english, 2001

54

The Wiskott-Aldrich Syndrome Protein Acts Downstream of CD2 and the CD2AP and PSTPIP1 Adaptors to Promote Formation of the Immunological Synapse

Karen Badour, Jinyi Zhang, Fabio Shi, Mary K.H McGavin, Vik Rampersad, Lynne A Hardy, Deborah Field, Katherine A Siminovitch

Journal:

Year:

2003

Language:

english

File:

PDF, 1.01 MB

english, 2003

55

Molecular characterization of the human immunoglobulin VλI germline gene repertoire

M.Denise Daley, Tsaiwei Olee, Peng Hong-Qi, Rafael W. Soto-Gil, Pojen P. Chen, Katherine A. Siminovitch

Journal:

Molecular Immunology

Year:

1992

Language:

english

File:

PDF, 1.45 MB

english, 1992

56

Molecular analysis of human immunoglobulin Vλ germline genes: Subgroups VλIII and VλIV

M.Denise Daley, Peng Hong-qi, Virginia Misener, Liu Xiao-Yuan, Pojen P. Chen, Katherine A. Siminovitch

Journal:

Molecular Immunology

Year:

1992

Language:

english

File:

PDF, 578 KB

english, 1992

57

Diagnostic misclassification of patients with presumed inflammatory bowel disease (IBD)

David N. Moskovitz, Mark S. Silverberg, Robin S. McLeod, Gordon R. Greenberg, Zane Cohen, Katherine A. Siminovitch, A. Hillary Steinhart

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

58

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn’s disease

Bill Newman, Xiangjun Gu, Richard Wintle, David Cescon, Mehrdad Yazdanpanah, Xiangdong Liu, Vanya Peltekova, Mark van Oene, Christopher I. Amos, Katherine A. Siminovitch

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 160 KB

english, 2005

59

Hepatic Cell–Type Specific Gene Expression Better Predicts HCV Treatment Outcome Than IL28B Genotype

Ian McGilvray, Jordan J. Feld, Limin Chen, Venessa Pattullo, Maha Guindi, Sandra Fischer, Ivan Borozan, Gang Xie, Nazia Selzner, E. Jenny Heathcote, Katherine Siminovitch

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 855 KB

english, 2012

60

Nonreceptor Protein-Tyrosine Phosphatases in Immune Cell Signaling

Pao, Lily I., Badour, Karen, Siminovitch, Katherine A., Neel, Benjamin G.

Journal:

Annual Review of Immunology

Year:

2007

Language:

english

File:

PDF, 939 KB

english, 2007

61

X-Chromosome inactivation in the Wiskott-Aldrich syndrome: A marker for detection of the carrier state and identfication of cell lineages expressing the gene defect

Greer, Wenda L., Kwong, Pak C., Peacocke, Monica, Ip, Peter, Rubin, Laurence A., Siminovitch, Katherine A.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.07 MB

english, 1989

62

Deploying next-generation sequencing in a hospital setting

Lars GT Jorgensen, Katherine Siminovitch

Journal:

BMC Proceedings

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

63

[Current Topics in Microbiology and Immunology] Signal Transduction and the Coordination of B Lymphocyte Development and Function I Volume 245/1 || Involvement of the Lymphocyte Cytoskeleton in Antigen-Receptor Signaling

Justement, Louis B., Siminovitch, Katherine A.

Year:

2000

Language:

english

File:

PDF, 4.58 MB

english, 2000

64

Primer: genomic and proteomic tools for the molecular dissection of disease

Walker, Erin J, Siminovitch, Katherine A

Journal:

Nature Clinical Practice Rheumatology

Year:

2007

Language:

english

File:

PDF, 564 KB

english, 2007

65

Anti-Jo-1 Autoantibodies and the Immunopathogenesis of Autoimmune Myositis

Tsui, Florence W. L., Siminovitch, Katherine A.

Journal:

International Reviews Of Immunology

Year:

1991

Language:

english

File:

PDF, 791 KB

english, 1991

66

Wiskott-Aldrich syndrome: New molecular and biochemical insights

Peacocke, Monica, Siminovitch, Katherine A.

Journal:

Journal of the American Academy of Dermatology

Year:

1992

Language:

english

File:

PDF, 2.12 MB

english, 1992

67

FEMALE SEX IS ASSOCIATED WITH ADVERSE CLINICAL AND ECHOCARDIOGRAPHIC MEASURES IN A GENETICALLY TESTED HYPERTROPHIC CARDIOMYOPATHY COHORT

Nam Hong, Susie, Gruner, Christiane, Chan, Raymond, Care, Melanie, Williams, Lynne, Li, Qin, Laczay, Balint, Siminovitch, Katherine, Woo, Anna, Manning, Warren, Rakowski, Harry

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 143 KB

english, 2013

68

Molecular characterization of the X-linked immunodeficiency diseases

Greer, Wenda L., Siminovitch, Katherine A.

Journal:

Clinical Immunology Newsletter

Year:

1994

Language:

english

File:

PDF, 1.15 MB

english, 1994

69

Effect of diagnostic misclassification on the ability to detect linkage in inflammatory bowel disease (IBD)

Silverberg, Mark S., Daly, Mark J., Rioux, John D., Mcleod, Robin S., Greenberg, Gordon R., Cohen, Zane, Lander, Eric S., Hudson, Tom, Siminovitch, Katherine A., Hillary Steinhart, A.

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

70

Linkage of the Wiskott--Aldrich Syndrome with Polymorphic DNA Sequences from the Human X Chromosome

Monica Peacocke and Katherine A. Siminovitch

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 667 KB

english, 1987

71

Genetics in PBC: What Do the “Risk Genes” Teach Us?

Hirschfield, Gideon M., Siminovitch, Katherine A.

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2015

Language:

english

File:

PDF, 169 KB

english, 2015

72

RFC1 80G>A Is a Genetic Determinant of Methotrexate Efficacy in Rheumatoid Arthritis: A Human Genome Epidemiologic Review and Meta-Analysis of Observational Studies

Kung, Tabitha N., Dennis, Jessica, Ma, YiQing, Xie, Gang, Bykerk, Vivian, Pope, Janet, Thorne, Carter, Keystone, Edward, Siminovitch, Katherine A., Gagnon, France

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 232 KB

english, 2014

73

Reply

Farrer, Lindsay A., Sherva, Richard, Merkel, Peter A., Siminovitch, Katherine A.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 31 KB

english, 2014

74

The Biologic Significance of Human Natural Autoimmune Responses: Relationship to the Germline, Early Immune and Malignant B Cell Variable Gene Repertoire

Siminovitch, Katherine A., Chen, Pojen P.

Journal:

International Reviews Of Immunology

Year:

1990

Language:

english

File:

PDF, 885 KB

english, 1990

75

Altered expression of leucocyte sialoglycoprotein in Wiskott-Aldrich syndrome is associated with a specific defect in O -glycosylation

Greer, Wenda L., Higgins, Elizabeth, Sutherland, D. Robert, Novogrodsky, Abraham, Brockhausen, Inka, Peacocke, Monica, Rubin, Laurence A., Baker, Michael, Dennis, James W., Siminovitch, Katherine A.

Journal:

Biochemistry and Cell Biology

Year:

1989

Language:

english

File:

PDF, 1.04 MB

english, 1989

76

From Human Autoantibodies to the Fetal Antibody Repertoire to B Cell Malignancy: It's a Small World After All

Chen, Pojen P., Olsen, Nancy J., Yang, Pei-Ming, Soto-Gil, Rafael W., Olee, Tsaiwei, Siminovitch, Katherine A., Carson, Dennis A.

Journal:

International Reviews Of Immunology

Year:

1990

Language:

english

File:

PDF, 966 KB

english, 1990

77

Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

Shi, Yongquan, Dong, Baoxia, Miliotis, Helen, Liu, Junye, Alberts, Arthur S., Zhang, Jinyi, Siminovitch, Katherine A.

Journal:

Biochemistry and Cell Biology

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

78

Genetic dissection of inflammatory bowel disease: unravelling etiology and improving diagnostics

Limdi, Jimmy K, Siminovitch, Katherine A, Newman, William

Journal:

Expert Review of Clinical Immunology

Year:

2005

Language:

english

File:

PDF, 371 KB

english, 2005

79

Phosphorylation of SHP-2 Regulates Interactions between the Endoplasmic Reticulum and Focal Adhesions to Restrict Interleukin-1-induced Ca 2+ Signaling

Wang, Qin, Abreu, Maria Teresa Herrera, Siminovitch, Katherine, Downey, Gregory P., McCulloch, Christopher A.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 2.00 MB

english, 2006

80

WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)

de la Fuente, Miguel A., Sasahara, Yoji, Calamito, Marco, Antón, Inés M., Elkhal, Abdallah, Gallego, Maria D., Suresh, Koduru, Siminovitch, Katherine, Ochs, Hans D., Anderson, Kenneth C., Rosen, Fred

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

81

T cell anergy is programmed early after exposure to bacterial superantigen in vivo

Yuh, Kouichi, Siminovitch, Katherine A., Ochi, Atsuo

Journal:

International Immunology

Year:

1993

Language:

english

File:

PDF, 2.92 MB

english, 1993

82

Whole genome amplification of buccal cell DNA: genotyping concordance before and after multiple displacement amplification

Thompson, Miles D., Bowen, Raffick A. R., Wong, Betty Y. L., Antal, Joan, Liu, Zhanqin, Yu, Helen, Siminovitch, Katherine, Kreiger, Nancy, Rohan, Tom E., Cole, David E. C.

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

83

The Arabidopsis SWI2/SNF2 Chromatin Remodeler BRAHMA Regulates Polycomb Function during Vegetative Development and Directly Activates the Flowering Repressor Gene SVP

Li, Chenlong, Chen, Chen, Gao, Lei, Yang, Songguang, Nguyen, Vi, Shi, Xuejiang, Siminovitch, Katherine, Kohalmi, Susanne E., Huang, Shangzhi, Wu, Keqiang, Chen, Xuemei, Cui, Yuhai, Schubert, Daniel

Journal:

Year:

2015

Language:

english

File:

PDF, 8.53 MB

english, 2015

84

Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca 2+ signalling, ERK activation and MMP-3 expression

Wang, Qin, Siminovitch, Katherine A., Downey, Gregory P., McCulloch, Christopher A.

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

85

The human kappa deleting element and the mouse recombining segment share DNA sequence homology

Siminovitch, Katherine A., Moore, Mark W., Durdik, Jeannine, Selsing, Erik

Journal:

Nucleic Acids Research

Year:

1987

Language:

english

File:

PDF, 346 KB

english, 1987

86

New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort

Nam, Robert K., Zhang, William, Siminovitch, Katherine, Shlien, Adam, Kattan, Michael W., Klotz, Laurence H., Trachtenberg, John, Lu, Yan, Zhang, Jinyi, Yu, Changhong, Toi, Ants, Loblaw, D. Andrew, Ve

Journal:

Cancer Biology & Therapy

Year:

2011

Language:

english

File:

PDF, 309 KB

english, 2011

87

Nucleotide sequence of the intron of the germline human x immunoglobulin gene connecting the J and C regions reveals a matrix association region (MAR) next to the enhancer

Whitehurst, Charles, Cheng, Jianbo, Henney, Henry R., Max, Edward E., Schroeder, Harry W., Stüber, Frank, Siminovitch, Katherine A., Garrard, William T.

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 134 KB

english, 1992

88

The New Immunology

Siminovitch, Katherine

Journal:

Journal of Reconstructive Microsurgery

Year:

1992

Language:

english

File:

PDF, 2.00 MB

english, 1992

89

SHP-1 Negatively Regulates Neuronal Survival by Functioning as a TrkA Phosphatase

H. Nicholas Marsh, Catherine I. Dubreuil, Celia Quevedo, Anna Lee, Marta Majdan, Gregory S. Walsh, Sharon Hausdorff, Farid Arab Said, Olga Zoueva, Maya Kozlowski, Katherine Siminovitch, Benjamin G. Ne

Journal:

The Journal of Cell Biology

Year:

2003

File:

PDF, 1.84 MB

2003

90

SHP-1 Negatively Regulates Neuronal Survival by Functioning as a TrkA Phosphatase

H. Nicholas Marsh, Catherine I. Dubreuil, Celia Quevedo, Anna Lee, Marta Majdan, Gregory S. Walsh, Sharon Hausdorff, Farid Arab Said, Olga Zoueva, Maya Kozlowski, Katherine Siminovitch, Benjamin G. Ne

Journal:

The Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 1.84 MB

english, 2003

91

Possible Deletion of a Developmentally Regulated Heavy-Chain Variable Region Gene in Autoimmune Diseases

Pei-Ming Yang, Nancy J. Olsen, Katherine A. Siminovitch, Tsaiwei Olee, Franklin Kozin, Dennis A. Carson and Pojen P. Chen

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.11 MB

english, 1990

92

Deep Basal Inferoseptal Crypts Occur More Commonly in Patients with Hypertrophic Cardiomyopathy Due to Disease-causing Myofilament Mutations

Deva, Djeven Parameshvara, Williams, Lynne K., Care, Melanie, Siminovitch, Katherine A., Moshonov, Hadas, Wintersperger, Bernd Juergen, Rakowski, Harry, Crean, Andrew Michael

Journal:

Year:

2013

Language:

english

File:

PDF, 818 KB

english, 2013

93

A review of economic evaluations of genetic testing services and interventions (2004–2009)

Djalalov, Sandjar, Musa, Zahra, Mendelson, Michael, Siminovitch, Katherine, Hoch, Jeffrey

Journal:

Genetics in Medicine

Year:

2011

Language:

english

File:

PDF, 253 KB

english, 2011

94

A Human Anti-Cardiolipin Autoantibody is Encoded by Developmentally restricted Heavy and Light Chain Variable Region Genes

Siminovitch, Katherine a., Misener, Virginia, Kwong, Pak C., Yang, Pei-Ming, Laskin, Carl A., Cairns, Ewa, Bell, David, Rubin, Laurence A., Chen, Pojen P.

Journal:

Year:

1990

File:

PDF, 942 KB

1990

95

A Human Anti-Cardiolipin Autoantibody is Encoded by Developmentally restricted Heavy and Light Chain Variable Region Genes

Siminovitch, Katherine a., Misener, Virginia, Kwong, Pak C., Yang, Pei-Ming, Laskin, Carl A., Cairns, Ewa, Bell, David, Rubin, Laurence A., Chen, Pojen P.

Journal:

Year:

1990

Language:

english

File:

PDF, 942 KB

english, 1990

96

Monoclonal Antibodies for the Treatment of Hypercholesterolemia: Targeting PCSK9

Alkindi, Manal, Siminovitch, Katherine A., Gupta, Milan, Genest, Jacques

Journal:

Canadian Journal of Cardiology

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

97

SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain

Kozlowski, Maya, Larose, Louise, Lee, Fai, Le, Duc Mingh, Rottapel, Robert, Siminovitch, Katherine A.

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 1.05 MB

english, 1998

98

A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate

Thompson, Miles D., Capra, Valérie, Takasaki, Jun, Maresca, Giovanna, Rovati, G. Enrico, Slutsky, Aurther S., Lilly, Craig, Zamel, Noe, McIntyre Burnham, W., Cole, David E., Siminovitch, Katherine A.

Journal:

Pharmacogenetics and Genomics

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

99

Genetic Variants in IL-23R and ATG16L1 Independently Predispose to Increased Susceptibility to Crohnʼs Disease in a Canadian Population

Newman, William G., Zhang, Qing, Liu, Xiangdong, Amos, Christopher I., Siminovitch, Katherine A.

Journal:

Journal of Clinical Gastroenterology

Year:

2009

Language:

english

File:

PDF, 102 KB

english, 2009

100

Prevalence and Clinical Implication of Double Mutations in Hypertrophic CardiomyopathyCLINICAL PERSPECTIVE

Fourey, Dana, Care, Melanie, Siminovitch, Katherine A., Weissler-Snir, Adaya, Hindieh, Waseem, Chan, Raymond H., Gollob, Michael H., Rakowski, Harry, Adler, Arnon

Journal:

Circulation Cardiovascular Genetics

Year:

2017

Language:

english

File:

PDF, 735 KB

english, 2017