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51

Fatal cerebral edema associated with serine deficiency in CSF

Keularts, Irene M. L. W., Leroy, Piet L. J. M., Rubio-Gozalbo, Estela M., Spaapen, Leo J. M., Weber, Biene, Dorland, Bert, Koning, Tom J., Verhoeven-Duif, Nanda M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 127 KB

english, 2010

52

Addendum to: “Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy” [Mol. Immunol. 55 (2013) 283–291]

Zheng, Yan, Zha, Yuanyuan, Spaapen, Robbert M., Mathew, Rebecca, Barr, Kenneth, Bendelac, Albert, Gajewski, Thomas F.

Journal:

Molecular Immunology

Year:

2013

Language:

english

File:

PDF, 184 KB

english, 2013

53

Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy

Zheng, Yan, Zha, Yuanyuan, Spaapen, Robbert M., Mathew, Rebecca, Barr, Kenneth, Bendelac, Albert, Gajewski, Thomas F.

Journal:

Molecular Immunology

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

54

Accurate quantitation of MHC-bound peptides by application of isotopically labeled peptide MHC complexes

Hassan, Chopie, Kester, Michel G.D., Oudgenoeg, Gideon, de Ru, Arnoud H., Janssen, George M.C., Drijfhout, Jan W., Spaapen, Robbert M., Jiménez, Connie R., Heemskerk, Mirjam H.M., Falkenburg, J.H. Fre

Journal:

Journal of Proteomics

Year:

2014

Language:

english

File:

PDF, 413 KB

english, 2014

55

Functional Characteristics of the High Affinity IgG Receptor, Fc RI

van der Poel, C. E., Spaapen, R. M., van de Winkel, J. G. J., Leusen, J. H. W.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

56

Purine Nucleoside Phosphorylase (PNP) Deficiency Leading to Accumulation of Lymphocytes in S-Phase

Rijkers, Ger T., Zegers, Ben J. M., Spaapen, Leo J. M., Rutgers, Derk H., Roord, John J., Kuis, Wietse, Stoop, Jan W.

Journal:

Pediatric Hematology-Oncology

Year:

1986

Language:

english

File:

PDF, 390 KB

english, 1986

57

Identification of minor histocompatibility antigens based on the 1000 Genomes Project

Oostvogels, R., Lokhorst, H. M., Minnema, M. C., van Elk, M., van den Oudenalder, K., Spierings, E., Mutis, T., Spaapen, R. M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

58

Therapeutic Activity of High-Dose Intratumoral IFN- Requires Direct Effect on the Tumor Vasculature

Spaapen, R. M., Leung, M. Y. K., Fuertes, M. B., Kline, J. P., Zhang, L., Zheng, Y., Fu, Y.-X., Luo, X., Cohen, K. S., Gajewski, T. F.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

59

Science and Technology in a Developing World || Science, Technology and Society Studies and Development Perspectives in South-North Transactions

Shinn, Terry, Spaapen, Jack, Krishna, Venni

Year:

1997

Language:

english

File:

PDF, 3.53 MB

english, 1997

60

461. Qualitative and Quantitative Luciferase Expression of Transduced Hematopoietic Cell Populations Using Bioluminescent Imaging (BLI)

ROZEMULLER, H, KOGGEL, I, SPAAPEN, R, HAGENBEEK, A, MARTENS, A

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

61

Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1

Oostvogels, R, Minnema, M C, van Elk, M, Spaapen, R M, te Raa, G D, Giovannone, B, Buijs, A, van Baarle, D, Kater, A P, Griffioen, M, Spierings, E, Lokhorst, H M, Mutis, T

Journal:

Year:

2013

Language:

english

File:

PDF, 484 KB

english, 2013

62

Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes

Hoppes, R., Oostvogels, R., Luimstra, J. J., Wals, K., Toebes, M., Bies, L., Ekkebus, R., Rijal, P., Celie, P. H. N., Huang, J. H., Emmelot, M. E., Spaapen, R. M., Lokhorst, H., Schumacher, T. N. M.,

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

63

Autologous engineering of cartilage

Emans, P. J., van Rhijn, L. W., Welting, T. J. M., Cremers, A., Wijnands, N., Spaapen, F., Voncken, J. W., Shastri, V. P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

64

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

Spaapen, R. M., Lokhorst, H. M., van den Oudenalder, K., Otterud, B. E., Dolstra, H., Leppert, M. F., Minnema, M. C., Bloem, A. C., Mutis, T.

Journal:

Journal of Experimental Medicine

Year:

2008

Language:

english

File:

PDF, 2.42 MB

english, 2008

65

Rapid Identification of Clinical Relevant Minor Histocompatibility Antigens via Genome-Wide Zygosity-Genotype Correlation Analysis

Spaapen, R. M., de Kort, R. A.L., van den Oudenalder, K., van Elk, M., Bloem, A. C., Lokhorst, H. M., Mutis, T.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 418 KB

english, 2009

66

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma

Scanu, Tiziana, Spaapen, Robbert M., Bakker, Jeroen M., Pratap, Chandra Bhan, Wu, Lin-en, Hofland, Ingrid, Broeks, Annegien, Shukla, Vijay Kumar, Kumar, Mohan, Janssen, Hans, Song, Ji-Ying, Neefjes-Bo

Journal:

Cell Host & Microbe

Year:

2015

Language:

english

File:

PDF, 3.36 MB

english, 2015

67

Partial N-acetyl-glutamate synthetase deficiency masquerading as a valproic acid-induced Reye-like syndrome

Forget, PPh, van Oosterhout, M., Bakker, JA, Wermuth, B., Vles, JSH, Spaapen, LJM

Journal:

Acta Paediatrica

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

68

Rebuilding Human Leukocyte Antigen Class II-Restricted Minor Histocompatibility Antigen Specificity in Recall Antigen-Specific T Cells by Adoptive T Cell Receptor Transfer: Implications for Adoptive Immunotherapy

Spaapen, R., van den Oudenalder, K., Ivanov, R., Bloem, A., Lokhorst, H., Mutis, T.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

69

Eradication of Medullary Multiple Myeloma by CD4+ Cytotoxic Human T Lymphocytes Directed at a Single Minor Histocompatibility Antigen

Spaapen, R. M., Groen, R. W. J., van den Oudenalder, K., Guichelaar, T., van Elk, M., Aarts-Riemens, T., Bloem, A. C., Storm, G., Martens, A. C., Lokhorst, H. M., Mutis, T.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 613 KB

english, 2010

70

PPAR inhibits NF- B-dependent transcriptional activation in skeletal muscle

Remels, A. H. V., Langen, R. C. J., Gosker, H. R., Russell, A. P., Spaapen, F., Voncken, J. W., Schrauwen, P., Schols, A. M. W. J.

Journal:

AJP Endocrinology and Metabolism

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

71

Assessing the value of research for society

Spaapen, J., Sylvain, C.

Journal:

Research Evaluation

Year:

1993

Language:

english

File:

PDF, 973 KB

english, 1993

72

Recurrent Leg Ulcers in a Young Man with Hyperhomocysteinemia, Factor V Leiden and Impaired Fibrinolysis

Kolbach, D. N., Veraart, J. C. J. M., Hamuly&#x000E1, k, K., Spaapen, L. J. M., Neumann, H. A. M.

Journal:

Acta Dermato Venereologica

Year:

2002

Language:

english

File:

PDF, 330 KB

english, 2002

73

A New Case of Purine Nucleoside Phosphorylase Deficiency: Enzymologic, Clinical, and Immunologic Characteristics

Rijksen, Gert, Kuis, Wietse, Wadman, Sybe K, Spaapen, Leo J M, Duran, Marinus, Voorbrood, B S, Staal, Gerard E J, Stoop, Jan W, Zegers, Ben J M

Journal:

Pediatric Research

Year:

1987

Language:

english

File:

PDF, 611 KB

english, 1987

74

Accumulation of Odd-Numbered Long-Chain Fatty Acids in Fetuses and Neonates with Inherited Disorders of Propionate Metabolism

Wendel, Udo, Baumgartner, Regula, Van Der Meer, Syb B, Spaapen, Leo J M

Journal:

Pediatric Research

Year:

1991

Language:

english

File:

PDF, 287 KB

english, 1991

75

TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

HASSINK, Gerco, KIKKERT, Marjolein, VOORDEN, Sjaak van, LEE, Shiow-Ju, SPAAPEN, Robbert, LAAR, Theo van, COLEMAN, Catherine S., BARTEE, Eric, FRÜH, Klaus, CHAU, Vincent, WIERTZ, Emmanuel

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 711 KB

english, 2005

76

A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect

Rozemuller, H., van der Spek, E., Bogers-Boer, L. H., Zwart, M. C., Verweij, V., Emmelot, M., Groen, R. W., Spaapen, R., Bloem, A. C., Lokhorst, H. M., Mutis, T., Martens, A. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 584 KB

english, 2008

77

Autologous Engineering of Cartilage

Pieter J. Emans, Lodewijk W. van Rhijn, Tim J. M. Welting, Andy Cremers, Nina Wijnands, Frank Spaapen, J. Willem Voncken, V. Prasad Shastri and Robert Langer

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

78

Salmonella manipulation of host signalling pathways promotes cellular transformation and cancer of infected tissues

Pratap, C.B., Scanu, T., Spaapen, R.M., Bakker, J.M., Wu, L.-E., Hofland, I., Broeks, A., Shukla, V.K., Kumar, M., Janssen, H., Song, J.-Y., Riele, H.T., Holden, D.W., Nath, G., Neefjes, J.

Journal:

International Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 53 KB

english, 2016

79

Are Children with Cystic Fibrosis Who Are Treated With a Proton-Pump Inhibitor at Risk for Vitamin B 12 Deficiency?

ter Heide, Henriëtte, Hendriks, Han J. E., Heijmans, Hiltje, Menheere, Paul P. C. A., Spaapen, Leo J. M., Bakker, Jaap A., Forget, Pierre-Philippe

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

80

The future of Evidence & Policy: moving forward from Valencia

Boaz, Annette, Coburn, Cynthia, Gough, David, Palinkas, Larry, Molas-Gallart, Jordi, Mortimer, Julia, Morton, Sarah, Oliver, Kathryn, Farley-Ripple, Liz, Spaapen, Jack, Tseng, Vivian

Journal:

Evidence & Policy A Journal of Research Debate and Practice

Year:

2016

Language:

english

File:

PDF, 61 KB

english, 2016

81

External Assessment and "Conditional Financing" of Research in Dutch Universities

S. S. BLUME and J. B. SPAAPEN

Journal:

Year:

1988

Language:

english

File:

PDF, 2.57 MB

english, 1988

82

Only modest contribution of the amplification loop after classical pathway initiated activation on human cells

Thielen, Astrid J.F., Meulenbroek, Elisabeth M., van Baarsen, Iris M., Jongsma, Marlieke L., van Mierlo, Gerard, Brouwer, Conny, Folman, Claudia, de Haas, Masja, Zeerleder, Sacha, Spaapen, Robbert M.,

Journal:

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

83

INTRACELLULAR PURINE AND PYRIMIDINE NUCLEOTIDE POOLS OF HUMAN T AND B LYMPHOCYTES OF DIFFERENT MATURATION STAGES: 203

Spaapen, Leo J M, Scharenberg, John G M, Zegers, Ben J M, Rijkers, Ger T, Duran, Marinus, Wadman, Sybe K

Journal:

Pediatric Research

Year:

1985

Language:

english

File:

PDF, 132 KB

english, 1985

84

THE EFFECT OF DEOXYGUANOSINE ON THE IN VITRO PROLIFERATION AND DIFFERENTIATION OF NORMAL HUMAN B LYMPHOCYTES: 181

Scharenberg, John G M, Spaapen, Leo J M, Rijkers, Ger T, Wadman, Syb K, Rijksen, Gert, Stoop, Jan H, Zegers, Ben J M

Journal:

Pediatric Research

Year:

1985

Language:

english

File:

PDF, 150 KB

english, 1985

85

Evaluation and monitoring of transdisciplinary collaborations

van Drooge, Leonie, Spaapen, Jack

Journal:

The Journal of Technology Transfer

Year:

2017

Language:

english

File:

PDF, 434 KB

english, 2017

86

THE INHIBITORY EFFECT OF DEOXYADENOSINE AND DEOXY GUANOSINE ON IN VITRO LYMPHOCYTE FUNCTION ARE EXPRESSED AT DIFFERENT STAGES OF LYMPHOCYTE ACTIVATION: 182

Scharenberg, John G M, Rijkers, Ger T, Toebes, Elly, Spaapen, Leo J M, Staal, Gerard E J, Zeger, Ben J M

Journal:

Pediatric Research

Year:

1985

Language:

english

File:

PDF, 150 KB

english, 1985

87

RESIDUAL PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY IN A NEW DUTCH PATIENT WITH PNP-DEFICIENCY AND CELLULAR IMMUNODEFICIENCY: 172

Rijksen, G, Zegers, B J M, Spaapen, L J M, Kuis, W, Duran, M, Voorbrood, B S, Staal, G E J, Wadman, S K

Journal:

Pediatric Research

Year:

1985

Language:

english

File:

PDF, 161 KB

english, 1985

88

CRISPR/Cas9 generated human CD46, CD55 and CD59 knockout cell lines as a tool for complement research

Thielen, Astrid J.F., van Baarsen, Iris M., Jongsma, Marlieke L., Zeerleder, Sacha, Spaapen, Robbert M., Wouters, Diana

Journal:

Journal of Immunological Methods

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

89

Secretome Screening Reveals Fibroblast Growth Factors as Novel Inhibitors of Viral Replication

van Asten, Saskia D., Raaben, Matthijs, Nota, Benjamin, Spaapen, Robbert M.

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 4.88 MB

english, 2018

90

MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

Prickaerts, Peggy, Niessen, Hanneke E. C., Dahlmans, Vivian E. H., Spaapen, Frank, Salvaing, Juliette, Vanhove, Jolien, Geijselaers, Claudia, Bartels, Stefanie J. J., Partouns, Iris, Neumann, Dietbert

Journal:

Year:

2015

Language:

english

File:

PDF, 9.39 MB

english, 2015

91

PRC1 Prevents Replication Stress during Chondrogenic Transit Amplification

Spaapen, Frank, Eijssen, Lars, Adriaens, Michiel, Welting, Tim, Prickaerts, Peggy, Salvaing, Juliette, Dahlmans, Vivian, Surtel, Donald, Kruitz, Frans, Kuijer, Roel, Takihara, Yoshihiro, Marks, Hendri

Journal:

Year:

2017

Language:

english

File:

PDF, 19.14 MB

english, 2017

92

The Role of Glycosphingolipids in Immune Cell Functions

Zhang, Tao, de Waard, Antonius A., Wuhrer, Manfred, Spaapen, Robbert M.

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 2.42 MB

2019

93

Effects of Morphine on Hypothalamic Noradrenaline and on Pituitary-Adrenal Activity in Rats

Van Ree, J.M., Versteeg, D.H.G., Spaapen-Kok, W.B., de Wied, D.

Journal:

Neuroendocrinology

Year:

1976

Language:

english

File:

PDF, 1.56 MB

english, 1976

94

Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR

Verstegen, Niels J. M., Unger, Peter-Paul A., Walker, Julia Z., Nicolet, Benoit P., Jorritsma, Tineke, van Rijssel, Jos, Spaapen, Robbert M., de Wit, Jelle, van Buul, Jaap D., ten Brinke, Anja, van Ha

Journal:

Frontiers in Immunology

Year:

2019

File:

PDF, 3.56 MB

2019

95

Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR

Verstegen, Niels J. M., Unger, Peter-Paul A., Walker, Julia Z., Nicolet, Benoit P., Jorritsma, Tineke, van Rijssel, Jos, Spaapen, Robbert M., de Wit, Jelle, van Buul, Jaap D., ten Brinke, Anja, van Ha

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 3.56 MB

english, 2019

96

The Connection Between Minor H Antigens and Neoantigens and the Missing Link in Their Prediction

Mutis, Tuna, Xagara, Anastasia, Spaapen, Robbert M.

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 727 KB

2020