St George–Hyslop, P.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

51

Genetic Factors in the Genesis of Alzheimer's Disease

P. H. ST GEORGE-HYSLOP

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 187 KB

english, 2000

52

The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid β-protein gene

Tanzi, Rudolph E., George-Hyslop, Peter H. St, Haines, Jonathan L., Polinsky, Ronald J., Nee, Linda, Foncin, Jean-Francois, Neve, Rachael L., McClatchey, Andrea I., Conneally, P. Michael, Gusella, Jam

Journal:

Year:

1987

File:

PDF, 269 KB

1987

53

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

St George-Hyslop, P. H., Haines, J. L., Farrer, L. A., Polinsky, R., Broeckhoven, C. Van, Goate, A., McLachlan, D. R. Crapper, Orr, H., Bruni, A. C., Sorbi, S.

Journal:

Year:

1990

File:

PDF, 451 KB

1990

54

10.1038/35024009

St George-Hyslop, Peter, Yu, Gang, Nishimura, Masaki, Arawaka, Shigeki, Levitan, Diane, Zhang, Lili, Tandon, Anurag, Song, You-Qiang, Rogaeva, Ekaterina, Chen, Fusheng, Kawarai, Toshitaka, Supala, Agn

Journal:

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

55

Alzheimer's disease: Selectively tuning γ-secretase

St George-Hyslop, Peter, Schmitt-Ulms, Gerold

Journal:

Year:

2010

Language:

english

File:

PDF, 179 KB

english, 2010

56

10.1038/5526

St George–Hyslop, P., Nishimura, M., Yu, G., Levesque, G., Zhang, D.M., Ruel, L., Chen, F., Milman, P., Holmes, E., Liang, Y., Kawarai, T., Jo, E., Supala, A., Rogaeva, E., Xu, D -M., Janus, C., Leves

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 311 KB

english, 1999

57

10.1038/75981

Germino, Gregory, Pei, York, Watnick, Terry, He, Ning, Wang, Kairong, Liang, Yan, Parfrey, Patrick, Hefferton, Donna, St George-Hyslop, Peter

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 338 KB

english, 2000

58

Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes

Rogaev, Evgeny I., Rogaeva, Ekaterina A., Ginter, Eugene K., Korovaitseva, Galina I., Farrer, Lindsay A., Shlensky, Alexander B., Pritkov, Alexander N., Mordovtsev, Vladimir N., St George-Hyslop, Pete

Journal:

Nature Genetics

Year:

1993

File:

PDF, 562 KB

1993

59

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

St George-Hyslop, P., Haines, J., Rogaev, E., Mortilla, M., Vaula, G., Pericak-Vance, M., Foncin, J-F, Montesi, M., Bruni, A., Sorbi, S.

Journal:

Nature Genetics

Year:

1992

File:

PDF, 797 KB

1992

60

Regulatory RNA goes awry in Alzheimer's disease

St George-Hyslop, Peter, Haass, Christian

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 229 KB

english, 2008

61

γ-SECRETASE, NOTCH, Aβ AND ALZHEIMER'S DISEASE: WHERE DO THE PRESENILINS FIT IN?

Sisodia, Sangram S., St George-Hyslop, Peter H.

Journal:

Nature Reviews Neuroscience

Year:

2002

Language:

english

File:

PDF, 1.36 MB

english, 2002

62

Piecing Together Alzheimer's

St George-Hyslop, Peter H.

Journal:

Scientific American

Year:

2000

Language:

english

File:

PDF, 1.24 MB

english, 2000

63

Germline mutational analysis of presenilin 1 and APP genes in Jewish-Israeli individuals with familial or early-onset Alzheimer disease using denaturing gradient gel electrophoresis (DGGE)

Reznik-Wolf, Haike, Treves, Therese A, Shabtai, Herzel, Aharon-Peretz, Judith, Chapman, Joab, Davidson, Michael, Barkai, Gad, St George Hyslop, Peter H, Goldman, Boleslaw, Korczyn, Amos D

Journal:

European Journal of Human Genetics

Year:

1998

Language:

english

File:

PDF, 1.20 MB

english, 1998

64

Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells

Verdile, G, Groth, D, Mathews, P M, St George-Hyslop, P, Fraser, P E, Ramabhadran, T V, Kwok, J B J, Schofield, P R, Carter, T, Gandy, S

Journal:

Molecular Psychiatry

Year:

2004

Language:

english

File:

PDF, 290 KB

english, 2004

65

Loss of nicastrin elicits an apoptotic phenotype in mouse embryos

Van Nguyen, Cynthia Hawkins, Catherine Bergeron, Agnes Supala, Jean Huang, David Westaway, Peter St George-Hyslop, Richard Rozmahel

Journal:

Year:

2006

Language:

english

File:

PDF, 451 KB

english, 2006

66

Targeting the amyloid-β antibody in the brain tissue of a mouse model of Alzheimer's disease

Daniel McLean, Michael J. Cooke, Yuanfei Wang, Paul Fraser, Peter St George-Hyslop, Molly S. Shoichet

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 677 KB

english, 2012

67

Alzheimer’s Aβ vaccination of rhesus monkeys (Macaca mulatta)

Sam Gandy, Ron B DeMattos, Cynthia A Lemere, Frank L Heppner, Jodi Leverone, Adriano Aguzzi, William B Ershler, Jinlu Dai, Paul Fraser, Peter St George Hyslop, David M Holtzman, Lary C Walker, Evan T

Journal:

Mechanisms of Ageing and Development

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

68

Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo

Sonya Brijbassi, Zareen Amtul, Susan Newbigging, David Westaway, Peter St George-Hyslop, Richard F. Rozmahel

Journal:

Neurobiology of Disease

Year:

2007

Language:

english

File:

PDF, 612 KB

english, 2007

69

Evidence for presenilin-1 involvement in amyloid angiopathy in the Alzheimer's disease-affected brain

Yorihide Hayashi, Ryo Fukatsu, Kayo Tsuzuki, Taku Yoshida, Nobuyuki Sasaki, Koichi Kimura, Haruyasu Yamaguchi, Peter H St. George-Hyslop, Nobuhiro Fujii, Naohiko Takahata

Journal:

Year:

1998

Language:

english

File:

PDF, 929 KB

english, 1998

70

Alzheimer's disease: advances in trafficking

Richard Mayeux, Peter St George Hyslop

Journal:

The Lancet Neurology

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

71

Recurrent fetal loss associated with bilineal inheritance of type 1 autosomal dominant polycystic kidney disease

Andrew D. Paterson, Kai Rong Wang, Doina Lupea, Peter St. George-Hyslop, York Pei

Journal:

American Journal of Kidney Diseases

Year:

2002

Language:

english

File:

PDF, 44 KB

english, 2002

72

Wild-Type and Mutated Nicastrins Do Not Display Aminopeptidase M- and B-like Activities

Anissa Fergani, G. Yu, Peter St. George-Hyslop, Frédéric Checler

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

73

γ-Secretase-like Cleavages of Notch and βAPP Are Mutually Exclusive in Human Cells

Agnès Petit, Peter St George-Hyslop, Paul Fraser, Frédéric Checler

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

74

APH-2/Nicastrin Functions in LIN-12/Notch Signaling in the Caenorhabditis elegans Somatic Gonad

Diane Levitan, Gang Yu, Peter St. George Hyslop, Caroline Goutte

Journal:

Developmental Biology

Year:

2001

Language:

english

File:

PDF, 226 KB

english, 2001

75

The Upstream Promoter of the β-Amyloid Precursor Protein Gene (APP) Shows Differential Patterns of Methylation in Human Brain

E.I. Rogaev, W.J. Lukiw, O. Lavrushina, E.A. Rogaeva, P.H. St. George-Hyslop

Journal:

Year:

1994

File:

PDF, 723 KB

1994

76

Analysis of the 5′ Sequence, Genomic Structure, and Alternative Splicing of thepresenilin-1Gene (PSEN1) Associated with Early Onset Alzheimer Disease

E.I. Rogaev, R. Sherrington, C. Wu, G. Levesque, Y. Liang, E.A. Rogaeva, M. Ikeda, K. Holman, C. Lin, W.J. Lukiw, P.J. de Jong, P.E. Fraser, J.M. Rommens, P. St George-Hyslop

Journal:

Year:

1997

Language:

english

File:

PDF, 388 KB

english, 1997

77

Defective membrane interactions of familial Parkinson’s disease mutant A30P α-synuclein

Euijung Jo, Nola Fuller, R.Peter Rand, Peter St George-Hyslop, Paul E Fraser

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

78

Aberrant Presenilin-1 Expression Downregulates LDL Receptor-Related Protein (LRP): Is LRP Central to Alzheimer's Disease Pathogenesis?

Emily Van Uden, George Carlson, Peter St. George-Hyslop, David Westaway, Robert Orlando, Margaret Mallory, Edward Rockenstein, Eliezer Masliah

Journal:

Molecular and Cellular Neuroscience

Year:

1999

Language:

english

File:

PDF, 594 KB

english, 1999

79

Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein

Martin Citron, Christopher B. Eckman, Thekla S. Diehl, Chris Corcoran, Beth L. Ostaszewski, Weiming Xia, Georges Levesque, Peter St. George Hyslop, Steven G. Younkin, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1998

Language:

english

File:

PDF, 315 KB

english, 1998

80

Alzheimer's Disease

Peter St. George-Hyslop

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 36 KB

english, 2000

81

Failure to detect missense mutations in the S182 gene in a series of late-onset Alzheimer's disease cases

T. Tsuda, H. Chi, Y. Liang, E.A. Rogaeva, R. Sherrington, G. Levesque, M. Ikeda, E.I. Rogaev, D. Pollen, M. Freedman, R. Duara, P.H. St. George-Hyslop

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 259 KB

english, 1995

82

Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families

Kouzin Kamino, Shinji Sato, Yoshiyuki Sakaki, Aoi Yoshiiwa, Yumiko Nishiwaki, Masatoshi Takeda, Hirotaka Tanabe, Tsuyoshi Nishimura, Kunio Ii, Peter H. St George-Hyslop, Tetsuro Miki, Toshio Ogihara

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 304 KB

english, 1996

83

The human NACP/α-synuclein gene: chromosome assignment to 4q21.3–q22 and TaqI RFLP analysis

Xiaohua Chen, H.A.Rohan de Silva, Mark J. Pettenati, P.Nagesh Rao, Peter St. George-Hyslop, Allen D. Roses, Yu Xia, Karen Horsburgh, Kenji Uéda, Tsunao Saitoh

Journal:

Year:

1995

Language:

english

File:

PDF, 297 KB

english, 1995

84

TMP21 regulates Aβ production but does not affect caspase-3, p53, and neprilysin

Virginia Dolcini, Julie Dunys, Jean Sevalle, Fusheng Chen, Marie-Victoire Guillot-Sestier, Peter St. George-Hyslop, Paul E. Fraser, Frédéric Checler

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 585 KB

english, 2008

85

Molecular biology and genetics of Alzheimer's disease

Peter H. St George-Hyslop, Agnès Petit

Journal:

Comptes Rendus Biologies

Year:

2005

File:

PDF, 175 KB

2005

86

Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene

Antonio Orlacchio, Toshitaka Kawarai, Mario Polidoro, Andrew D Paterson, Ekaterina Rogaeva, Aldo Orlacchio, Peter H St George-Hyslop, Giorgio Bernardi

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 85 KB

english, 2004

87

No evidence for tau duplications in frontal temporal dementia families showing genetic linkage to the tau locus in which tau mutations have not been found

Janel Johnson, Jovanka Ostojic, Lars Lannfelt, Anna Glaser, Hans Basun, Ekaterina Rogaeva, Toshitaka Kawarai, Amalia Bruni, Peter H. St. George Hyslop, Alison Goate, Pau Pastor, Sumi Chakraverty, Joan

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

88

Genetic association study of PINK1 coding polymorphisms in Parkinson's disease

Justus L. Groen, Toshitaka Kawarai, Anna Toulina, Chiara Rivoiro, Shabnam Salehi-Rad, Christine Sato, Angharad Morgan, Yan Liang, Ronald B. Postuma, Peter St George-Hyslop, Anthony E. Lang, Ekaterina

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

89

Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease

Nobuto Shibata, Toshitaka Kawarai, Joseph H. Lee, Hye-Seung Lee, Eri Shibata, Christine Sato, Yan Liang, Rajan Duara, Richard P. Mayeux, Peter H. St George-Hyslop, Ekaterina Rogaeva

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

90

Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related γ-secretase

Nobuo Sanjo, Taiichi Katayama, Hiroshi Hasegawa, Haifeng Jin, Monika Duthie, Howard T.J. Mount, Hidehiro Mizusawa, Peter St George-Hyslop, Paul E. Fraser

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

91

Impaired conditioned taste aversion learning in APP transgenic mice

Christopher Janus, Hans Welzl, Amanda Hanna, Lana Lovasic, Nancy Lane, Peter St. George-Hyslop, David Westaway

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

92

Transient abundance of presenilin 1 fragments/nicastrin complex associated with synaptogenesis during development in rat cerebellum

Toshiki Uchihara, Nobuo Sanjo, Ayako Nakamura, Kyung Han, Si-Young Song, Peter St. George-Hyslop, Paul E. Fraser

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 808 KB

english, 2006

93

The effects of APOE and tau gene variability on risk of frontotemporal dementia

L. Bernardi, R.G. Maletta, C. Tomaino, N. Smirne, M. Di Natale, M. Perri, T. Longo, R. Colao, S.A.M. Curcio, G. Puccio, M. Mirabelli, T. Kawarai, E. Rogaeva, P.H. St. George Hyslop, G. Passarino, G. D

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 242 KB

english, 2006

94

Association between variants in IDE-KIF11-HHEX and plasma amyloid β levels

Christiane Reitz, Rong Cheng, Nicole Schupf, Joseph H. Lee, Pankaj D. Mehta, Ekaterina Rogaeva, Peter St George-Hyslop, Richard Mayeux

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

95

Identification of Alzheimer disease-associated variants in genes that regulate retromer function

Badri N. Vardarajan, Sophia Y. Bruesegem, Michael E. Harbour, Peter St. George-Hyslop, Matthew N.J. Seaman, Lindsay A. Farrer

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 3.07 MB

english, 2012

96

Genetic association of CR1 with Alzheimer's disease: A tentative disease mechanism

Lili-Naz Hazrati, Caroline Van Cauwenberghe, Patricia L. Brooks, Nathalie Brouwers, Mahdi Ghani, Christine Sato, Marc Cruts, Kristel Sleegers, Peter St. George-Hyslop, Christine Van Broeckhoven, Ekate

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

97

Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP

Raphaëlle Pardossi-Piquard, Agnès Petit, Toshitaka Kawarai, Claire Sunyach, Cristine Alves da Costa, Bruno Vincent, Sabine Ring, Luciano D’Adamio, Jie Shen, Ulrike Müller, Peter St. George Hyslop, Fré

Journal:

Year:

2005

Language:

english

File:

PDF, 780 KB

english, 2005

98

Response to Correspondence: Pardossi-Piquard et al., “Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP.” Neuron 46, 541–554

Raphaëlle Pardossi-Piquard, Julie Dunys, Toshitaka Kawarai, Claire Sunyach, Cristine Alves da Costa, Bruno Vincent, Jean Sévalle, Sanjay Pimplikar, Peter St George-Hyslop, Frédéric Checler

Journal:

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

99

Family reunion – The ZIP/prion gene family

Sepehr Ehsani, Hairu Huo, Ashkan Salehzadeh, Cosmin L. Pocanschi, Joel C. Watts, Holger Wille, David Westaway, Ekaterina Rogaeva, Peter H. St. George-Hyslop, Gerold Schmitt-Ulms

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 584 KB

english, 2011

100

Lewy Bodies Contain Altered α-Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes

Carol F. Lippa, Hideo Fujiwara, David M.A. Mann, Benoit Giasson, Minami Baba, Marie L. Schmidt, Linda E. Nee, Brendan O'Connell, Dan A. Pollen, Peter St. George-Hyslop, Bernardino Ghetti, David Nochli

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 520 KB

english, 1998