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1

Percutaneous drug penetration: Choosing candidates for transdermal development

Dr. Gordon L. Flynn, Barbra Stewart

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 1.14 MB

english, 1988

2

Transport properties are not altered across Caco-2 cells with heightened TEER despite underlying physiological and ultrastructural changes

Sun Lu, Alec W. Gough, Walter F. Bobrowski, Barbra H. Stewart

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 301 KB

english, 1996

3

Physicochemical and drug-delivery considerations for oral drug bioavailability

O. Helen Chan, Barbra H. Stewart

Journal:

Drug Discovery Today

Year:

1996

Language:

english

File:

PDF, 1.25 MB

english, 1996

4

Urgent versus post-stabilisation antiretroviral treatment in hospitalised HIV-infected children in Kenya (PUSH): a randomised controlled trial

Njuguna, Irene N, Cranmer, Lisa M, Otieno, Vincent O, Mugo, Cyrus, Okinyi, Hellen M, Benki-Nugent, Sarah, Richardson, Barbra, Stern, Joshua, Maleche-Obimbo, Elizabeth, Wamalwa, Dalton C, John-Stewart,

Journal:

Year:

2018

Language:

english

File:

PDF, 691 KB

english, 2018

5

Influenza-Induced Interferon Lambda Response Is Associated With Longer Time to Delivery Among Pregnant Kenyan Women

Seiler, Christof, Bayless, Nicholas L., Vergara, Rosemary, Pintye, Jillian, Kinuthia, John, Osborn, Lusi, Matemo, Daniel, Richardson, Barbra A., John-Stewart, Grace, Holmes, Susan, Blish, Catherine A.

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 1.26 MB

2020

6

Improved intestinal transport of PD 158473, an N-methyl-D-aspartate (NMDA) antagonist, by involvement of multiple transporters

Doo-Man Oh, Hyo-Kyung Han, Rufus M. Williamson, Christopher F. Bigge, Gordon L. Amidon, Barbra H. Stewart, Narayanan Surendran

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

7

Uptake of prodrugs by rat intestinal mucosal cells: Mechanism and pharmaceutical implications

Barbra H. Stewart, Gordon L. Amidon, R. Kay Brabec

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 850 KB

english, 1986

8

Development and validation of an ion-pair reversed-phase high-performance liquid chromatographic method for the separation of phosphonodipeptides

Narayanan Surendran, Charles J. Stankovic, Barbra H. Stewart

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 461 KB

english, 1997

9

Automated sample preparation for drugs in plasma using a solid-phase extraction workstation

Tresavon D Parker III, Narayanan Surendran, Barbra H Stewart, David T Rossi

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1998

Language:

english

File:

PDF, 182 KB

english, 1998

10

Phosphate prodrugs of PD154075

Zhijian Zhu, Huai-Gu Chen, Om P Goel, O.Helen Chan, Linda A Stilgenbauer, Barbra H Stewart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

11

γ-Carbamate butenolide analogues as potent ETA selective endothelin receptor antagonists and prodrugs

William C. Patt, Billy R. Reisdorph, Joseph T. Repine, Annette M. Doherty, Stephen J. Haleen, Donnelle M. Walker, Kathleen M. Welch, Michael A. Flynn, Hussein Hallak, Eric L. Reyner, Barbra H. Stewart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 272 KB

english, 1997

12

Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children: a randomized clinical trial

Dalton C Wamalwa, Carey Farquhar, Elizabeth M Obimbo, Sara Selig, Dorothy A Mbori-Ngacha, Barbra A Richardson, Julie Overbaugh, Thaddeus Egondi, Irene Inwani, Grace John-Stewart

Journal:

Journal of the International AIDS Society

Year:

2009

Language:

english

File:

PDF, 295 KB

english, 2009

13

Absorption of Cam-2445, an NK1 neurokinin receptor antagonist: In vivo, in situ, and in vitro evaluations

O. Helen Chan, Heidi L. Schmid, Be-Sheng Kuo, D. Scott Wright, William Howson, Barbra H. Stewart

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 189 KB

english, 1996

14

CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs

Hyo-kyung Han, Julie K. Rhie, Doo-man Oh, Go Saito, Cheng-pang Hsu, Barbra H. Stewart, Gordon L. Amidon

Journal:

Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 69 KB

english, 1999

15

Use of immobilized artificial membrane chromatography for drug transport applications

Barbra H. Stewart, O. Helen Chan

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 225 KB

english, 1998

16

Atorvastatin Transport in the Caco-2 Cell Model: Contributions of P-Glycoprotein and the Proton-Monocarboxylic Acid Co-Transporter

Xiaochun Wu, Lloyd R. Whitfield, Barbra H. Stewart

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 196 KB

english, 2000

17

Hydrophobicity of HIV Protease Inhibitors by Immobilized Artificial Membrane Chromatography: Application and Significance to Drug Transport

Barbra H. Stewart, Francis Y. Chung, Bradley Tait, C. John, O. Helen Chan

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 459 KB

1998

18

Evaluation of a Targeted Prodrug Strategy to Enhance Oral Absorption of Poorly Water-Soluble Compounds

O. Helen Chan, Heidi L. Schmid, Linda A. Stilgenbauer, William Howson, David C. Horwell, Barbra H. Stewart

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 651 KB

1998

19

Comparison of Intestinal Permeabilities Determined in Multiplein VitroandinSituModels: Relationship to Absorption in Humans

Barbra H. Stewart, O. Helen Chan, Rosalind H. Lu, Eric L. Reyner, Heidi L. Schmid, Harriet W. Hamilton, Bruce A. Steinbaugh, Michael D. Taylor

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.44 MB

1995

20

Reconversion of Fosphenytoin in the Presence of Intestinal Alkaline Phosphatase

Christopher N. TenHoor, Barbra H. Stewart

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 711 KB

1995

21

Evidence for Overlapping Substrate Specificity Between Large Neutral Amino Acid (LNAA) and Dipeptide (hPEPTl) Transporters for PD 158473, an NMDA Antagonist

Narayanan Surendran, Kuang-Ming Y. Covitz, Hyo-kyung Han, Wolfgang Sadee, Doo-Man Oh, Gordon L. Amidon, Rufus M. Williamson, Christopher F. Bigge, Barbra H. Stewart

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 894 KB

1999

22

Transport of Pregabalin in Rat Intestine and Caco-2 Monolayers

Nancy Jezyk, Cheng Li, Barbra H. Stewart, Xiaochun Wu, Howard N. Bockbrader, David Fleisher

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.29 MB

1999

23

A Saturable Transport Mechanism in the Intestinal Absorption of Gabapentin Is the Underlying Cause of the Lack of Proportionality Between Increasing Dose and Drug Levels in Plasma

Barbra H. Stewart, Alan R. Kugler, Paul R. Thompson, Howard N. Bockbrader

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1006 KB

1993

24

Discrimination between drug candidates using models for evaluation of intestinal absorption

Barbra H. Stewart, O.Helen Chan, Nancy Jezyk, David Fleisher

Journal:

Advanced Drug Delivery Reviews

Year:

1997

Language:

english

File:

PDF, 2.00 MB

english, 1997

25

Worsening Central Sarcopenia and Increasing Intra-Abdominal Fat Correlate with Decreased Survival in Patients with Adrenocortical Carcinoma

Miller, Barbra S., Ignatoski, Kathleen M., Daignault, Stephanie, Lindland, Ceit, Doherty, Megan, Gauger, Paul G., Hammer, Gary D., Wang, Stewart C., Doherty, Gerard M.

Journal:

World Journal of Surgery

Year:

2012

Language:

english

File:

PDF, 294 KB

english, 2012

26

Improved oral drug delivery: solubility limitations overcome by the use of prodrugs

David Fleisher, Ramon Bong, Barbra H. Stewart

Journal:

Advanced Drug Delivery Reviews

Year:

1996

Language:

english

File:

PDF, 1.47 MB

english, 1996

27

A quantitative tool to assess degree of sarcopenia objectively in patients with hypercortisolism

Barbra S. Miller, Kathleen M. Ignatoski, Stephanie Daignault, Ceit Lindland, Paul G. Gauger, Gerard M. Doherty, Stewart C. Wang

Journal:

Year:

2011

Language:

english

File:

PDF, 271 KB

english, 2011

28

Multiple-model evaluation of absorption of a tachykinin receptor antagonist

O.Helen Chan, Michael W. Sinz, Barbra H. Stewart

Journal:

Advanced Drug Delivery Reviews

Year:

1997

Language:

english

File:

PDF, 880 KB

english, 1997

29

Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya: a prospective cohort

Dalton C Wamalwa, Elizabeth M Obimbo, Carey Farquhar, Barbra A Richardson, Dorothy A Mbori-Ngacha, Irene Inwani, Sara Benki-Nugent, Grace John-Stewart

Journal:

Year:

2010

Language:

english

File:

PDF, 533 KB

english, 2010

30

Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma

John Kinuthia, James N Kiarie, Carey Farquhar, Barbra A Richardson, Ruth Nduati, Dorothy Mbori-Ngacha, Grace John-Stewart

Journal:

Journal of the International AIDS Society

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

31

Nonpeptidic HIV Protease Inhibitors: 4-Hydroxy-pyran-2-one Inhibitors with Functional Tethers to P1Phenyl Ring to Reach S3Pocket of the Enzyme

J.V.N. Vara Prasad, Peter J. Tummino, Donna Ferguson, James Saunders, Steve Vander Roest, Thomas J. McQuade, Andrea Heldsinger, Eric L. Reyner, Barbra H. Stewart, Robert J. Guttendorf, Kimberly S. Par

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 624 KB

english, 1996

32

Separate and shared lysosomal transport of branched and aromatic dipolar amino acids

Barbra H. Stewart, Ellen J. Collarini, Ronald L. Pisoni, Halvor N. Christensen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1989

Language:

english

File:

PDF, 822 KB

english, 1989

33

In vitro assessment of oral delivery for hexapeptide endothelin antagonists

Barbra H. Stewart, Eric L. Reyner, Emmett Tse, Roger N. Hayes, Stephen Wetness, John X. He, Wayne L. Cody, Annette M. Doherty

Journal:

Year:

1996

Language:

english

File:

PDF, 816 KB

english, 1996

34

In vitro stability and intestinal absorption characteristics of hexapeptide endothelin receptor antagonists

Hyo-kyung Han, Barbra H. Stewart, Annette M. Doherty, Wayne L. Cody, Gordon L. Amidon

Journal:

Year:

1998

Language:

english

File:

PDF, 719 KB

english, 1998

35

Breastfeeding in HIV-1-positive mothers

Ruth Nduati, Barbra A Richardson, Grace John Stewart, Dorothy A Mbori-Ngacha, Joan Kreiss

Journal:

Year:

2001

Language:

english

File:

PDF, 42 KB

english, 2001

36

Empiric deworming to delay HIV disease progression in adults with HIV who are ineligible for initiation of antiretroviral treatment (the HEAT study): a multi-site, randomised trial

Judd Walson, Benson Singa, Laura Sangaré, Jaqueline Naulikha, Benjamin Piper, Barbra Richardson, Phelgona Apondi Otieno, Loice Wangari Mbogo, James A Berkley, Grace John-Stewart

Journal:

The Lancet Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 231 KB

english, 2012

37

Evaluation of Physicochemical Parameters Important to the Oral Bioavailability of Peptide-like Compounds: Implications for the Synthesis of Renin Inhibitors

Hamilton, Harriet W., Steinbaugh, Bruce A., Stewart, Barbra H., Chan, O. Helen, Schmid, Heidi L., Schroeder, Richard, Ryan, Michael J., Keiser, Joan, Taylor, Michael D.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.44 MB

english, 1995

38

Design of a Potent Combined Pseudopeptide Endothelin-A/Endothelin-B Receptor Antagonist, Ac- d Bhg 16 -Leu-Asp-Ile-[NMe]Ile-Trp 21 (PD 156252): Examination of Its Pharmacokinetic and Spectral Properties

Cody, Wayne L., He, John X., Reily, Michael D., Haleen, Stephen J., Walker, Donnelle M., Reyner, Eric L., Stewart, Barbra H., Doherty, Annette M.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 285 KB

english, 1997

39

Correlates and outcomes of preterm birth, low birth weight, and small for gestational age in HIV-exposed uninfected infants

Slyker, Jennifer A, Patterson, Janna, Ambler, Gwen, Richardson, Barbra A, Maleche-Obimbo, Elizabeth, Bosire, Rose, Mbori-Ngacha, Dorothy, Farquhar, Carey, John-Stewart, Grace

Journal:

BMC Pregnancy and Childbirth

Year:

2014

Language:

english

File:

PDF, 224 KB

english, 2014

40

Use of Principal Components Analysis and Protein Microarray to Explore the Association of HIV-1-Specific IgG Responses with Disease Progression

Gerns Storey, Helen L., Richardson, Barbra A., Singa, Benson, Naulikha, Jackie, Prindle, Vivian C., Diaz-Ochoa, Vladimir E., Felgner, Phil L., Camerini, David, Horton, Helen, John-Stewart, Grace, Wals

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 626 KB

english, 2014

41

Prevalence, perceptions, and correlates of pediatric HIV disclosure in an HIV treatment program in Kenya

John-Stewart, Grace C., Wariua, Grace, Beima-Sofie, Kristin M., Richardson, Barbra A., Farquhar, Carey, Maleche-Obimbo, Elizabeth, Mbori-Ngacha, Dorothy, Wamalwa, Dalton

Journal:

Year:

2013

Language:

english

File:

PDF, 140 KB

english, 2013

42

HIV Protease Inhibitors Possessing a Novel, High-Affinity, and Achiral P1'/P2' Ligand with a Unique Pattern of in Vitro Resistance. Importance of a Conformationally-Restricted Template in the Design of Enzyme Inhibitors

Prasad, J. V. N. Vara, Lunney, Elizabeth A., Ferguson, Donna, Tummino, Peter J., Rubin, J. Ronald, Reyner, Eric L., Stewart, Barbra H., Guttendorf, Robert J., Domagala, John M.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.21 MB

english, 1995

43

Prevalence and correlates of insecticide-treated bednet use among HIV-1-infected adults in Kenya

Nnedu, Obinna N., John-Stewart, Grace C., Singa, Benson O., Piper, Ben, Otieno, Phelgona A., Guidry, Alicia, Richardson, Barbra A., Walson, Judd

Journal:

Year:

2012

Language:

english

File:

PDF, 120 KB

english, 2012

44

The consequences of post-election violence on antiretroviral HIV therapy in Kenya

Pyne-Mercier, Lee D., John-Stewart, Grace C., Richardson, Barbra A., Kagondu, Njeri L., Thiga, Joan, Noshy, Haidy, Kist, Nadia, Chung, Michael H.

Journal:

Year:

2011

Language:

english

File:

PDF, 297 KB

english, 2011

45

Longitudinal Comparison of Chemokines in Breastmilk Early Postpartum Among HIV-1-Infected and Uninfected Kenyan Women

Bosire, Rose, Guthrie, Brandon L., Lohman-Payne, Barbara, Mabuka, Jennifer, Majiwa, Maxwell, Wariua, Grace, Mbori-Ngacha, Dorothy, Richardson, Barbra, John-Stewart, Grace, Farquhar, Carey

Journal:

Breastfeeding Medicine

Year:

2007

Language:

english

File:

PDF, 185 KB

english, 2007

46

Short Communication: T Cell Activation in HIV-1/Herpes Simplex Virus-2-Coinfected Kenyan Women Receiving Valacyclovir

Roxby, Alison C., Liu, Amy Y., Drake, Alison L., Kiarie, James N., Richardson, Barbra, Lohman-Payne, Barbara L., John-Stewart, Grace C., Wald, Anna, De Rosa, Stephen, Farquhar, Carey

Journal:

AIDS Research and Human Retroviruses

Year:

2013

Language:

english

File:

PDF, 143 KB

english, 2013

47

Breast‐Milk Infectivity in Human Immunodeficiency Virus Type 1–Infected Mothers

Richardson, Barbra A., John‐Stewart, Grace C., Hughes, James P., Nduati, Ruth, Mbori‐Ngacha, Dorothy, Overbaugh, Julie, Kreiss, Joan K.

Journal:

The Journal of Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 85 KB

english, 2003

48

High-risk enteric pathogens associated with HIV infection and HIV exposure in Kenyan children with acute diarrhoea

Pavlinac, Patricia B., John-Stewart, Grace C., Naulikha, Jaqueline M., Onchiri, Frankline M., Denno, Donna M., Odundo, Elizabeth A., Singa, Benson O., Richardson, Barbra A., Walson, Judd L.

Journal:

Year:

2014

Language:

english

File:

PDF, 373 KB

english, 2014

49

Oligonucleotide Ligation Assay Detects HIV Drug Resistance Associated With Virologic Failure Among Antiretroviral-Naive Adults in Kenya

Chung, Michael H., Beck, Ingrid A., Dross, Sandra, Tapia, Kenneth, Kiarie, James N., Richardson, Barbra A., Overbaugh, Julie, Sakr, Samah R., John-Stewart, Grace C., Frenkel, Lisa M.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2014

Language:

english

File:

PDF, 605 KB

english, 2014

50

Association of Levels of HIV‐1–Infected Breast Milk Cells and Risk of Mother‐to‐Child Transmission

Rousseau, Christine M., Nduati, Ruth W., Richardson, Barbra A., John‐Stewart, Grace C., Mbori‐Ngacha, Dorothy A., Kreiss, Joan K., Overbaugh, Julie

Journal:

The Journal of Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 517 KB

english, 2004

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