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101

Class III Polyhydroxybutyrate Synthase: Involvement in Chain Termination and Reinitiation †

Tian, Jiamin, Sinskey, Anthony J., Stubbe, JoAnne

Journal:

Year:

2005

Language:

english

File:

PDF, 308 KB

english, 2005

102

Detection of a New Substrate-Derived Radical during Inactivation of Ribonucleotide Reductase from Escherichia coli by Gemcitabine 5‘-Diphosphate †

van der Donk, Wilfred A., Yu, Guixue, Pérez, Lucy, Sanchez, Raylene J., Stubbe, JoAnne, Samano, Vicente, Robins, Morris J.

Journal:

Year:

1998

Language:

english

File:

PDF, 143 KB

english, 1998

103

Mechanism of Inactivation of Human Ribonucleotide Reductase with p53R2 by Gemcitabine 5′-Diphosphate

Wang, Jun, Lohman, Gregory J. S., Stubbe, JoAnne

Journal:

Year:

2009

Language:

english

File:

PDF, 1.51 MB

english, 2009

104

Radicals in biological catalysis

Journal:

Year:

1988

Language:

english

File:

PDF, 857 KB

english, 1988

105

The Core Structure of X Generated in the Assembly of the Diiron Cluster of Ribonucleotide Reductase: 17 O 2 and H 217 O ENDOR

Burdi, Doug, Willems, Jean-Paul, Riggs-Gelasco, Pam, Antholine, William E., Stubbe, JoAnne, Hoffman, Brian M.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

106

An ENDOR study of the tyrosyl free radical in ribonucleotide reductase from Escherichia coli

Bender, Christopher J., Sahlin, Margareta, Babcock, Gerald T., Barry, Bridgette A., Chandrashekar, T. K., Salowe, Scott P., Stubbe, JoAnne, Lindstroem, Bjoern, Petersson, Leif

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 1.01 MB

english, 1989

107

Mechanism of Assembly of the Dimanganese-Tyrosyl Radical Cofactor of Class Ib Ribonucleotide Reductase: Enzymatic Generation of Superoxide Is Required for Tyrosine Oxidation via a Mn(III)Mn(IV) Intermediate

Cotruvo, Joseph A., Stich, Troy A., Britt, R. David, Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.01 MB

english, 2013

108

Lipases Provide a New Mechanistic Model for Polyhydroxybutyrate (PHB) Synthases: Characterization of the Functional Residues in Chromatium vinosum PHB Synthase †

Jia, Yong, Kappock, T. Joseph, Frick, Tobias, Sinskey, Anthony J., Stubbe, JoAnne

Journal:

Year:

2000

Language:

english

File:

PDF, 284 KB

english, 2000

109

Interaction of Co.cntdot.Bleomycin A2 (Green) with d(CCAGGCCTGG)2: Evidence for Intercalation Using 2D NMR

Wu, Wei, Vanderwall, Dana E., Stubbe, JoAnne, Kozarich, John W., Turner, Chris J.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 254 KB

english, 1994

110

Synthesis and Characterization of Oligonucleotides Containing a 4‘-Keto Abasic Site †

Chen, Jingyang, Stubbe, JoAnne

Journal:

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

111

Electron Microbeam Investigation of Uranium-Contaminated Soils from Oak Ridge, TN, USA

Stubbs, Joanne E., Elbert, David C., Veblen, David R., Zhu, Chen

Journal:

Environmental Science & Technology

Year:

2006

Language:

english

File:

PDF, 974 KB

english, 2006

112

PHA Synthase from Chromatium vinosum : Cysteine 149 Is Involved in Covalent Catalysis †

Müh, Ute, Sinskey, Anthony J., Kirby, Daniel P., Lane, William S., Stubbe, JoAnne

Journal:

Year:

1999

Language:

english

File:

PDF, 136 KB

english, 1999

113

Mechanism of action of enolase: effect of the .beta.-hydroxy group on the rate of dissociation of the .alpha.-carbon-hydrogen bond

Stubbe, JoAnne, Abeles, Robert H.

Journal:

Year:

1980

Language:

english

File:

PDF, 1.05 MB

english, 1980

114

Escherichia coli Class Ib Ribonucleotide Reductase Contains a Dimanganese(III)-Tyrosyl Radical Cofactor in Vivo

Cotruvo, Joseph A., Stubbe, JoAnne

Journal:

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

115

Nuclear Magnetic Resonance Structural Studies and Molecular Modeling of Duplex DNA Containing Normal and 4‘-Oxidized Abasic Sites †,‡

Chen, Jingyang, Dupradeau, François-Yves, Case, David A., Turner, Christopher J., Stubbe, JoAnne

Journal:

Year:

2007

Language:

english

File:

PDF, 575 KB

english, 2007

116

Inorganic pyrophosphate is released from 2'-chloro-2'-deoxyuridine 5'-diphosphate by ribonucleoside diphosphate reductase

Stubbe, JoAnne, Kozarich, John W.

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 441 KB

english, 1980

117

Determination of the in Vivo Stoichiometry of Tyrosyl Radical per ββ‘ in Saccharomyces cerevisiae Ribonucleotide Reductase †

Ortigosa, Allison D., Hristova, Daniela, Perlstein, Deborah L., Zhang, Zhen, Huang, Mingxia, Stubbe, JoAnne

Journal:

Year:

2006

Language:

english

File:

PDF, 246 KB

english, 2006

118

PELDOR Spectroscopy with DOPA-β2 and NH 2 Y-α2s: Distance Measurements between Residues Involved in the Radical Propagation Pathway of E. coli Ribonucleotide Reductase

Seyedsayamdost, Mohammad R., Chan, Clement T. Y., Mugnaini, Veronica, Stubbe, JoAnne, Bennati, Marina

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 377 KB

english, 2007

119

Insight into the Mechanism of Inactivation of Ribonucleotide Reductase by Gemcitabine 5′-Diphosphate in the Presence or Absence of Reductant

Artin, Erin, Wang, Jun, Lohman, Gregory J. S., Yokoyama, Kenichi, Yu, Guixue, Griffin, Robert G., Bar, Galit, Stubbe, JoAnne

Journal:

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

120

Pulsed ELDOR Spectroscopy Measures the Distance between the Two Tyrosyl Radicals in the R2 Subunit of the E. coli Ribonucleotide Reductase

Bennati, Marina, Weber, Axel, Antonic, Jelena, Perlstein, Deborah L., Robblee, John, Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 47 KB

english, 2003

121

N 5 -CAIR Mutase: Role of a CO 2 Binding Site and Substrate Movement in Catalysis †,‡

Hoskins, Aaron A., Morar, Mariya, Kappock, T. Joseph, Mathews, Irimpan I., Zaugg, Judith B., Barder, Timothy E., Peng, Paul, Okamoto, Akimitsu, Ealick, Steven E., Stubbe, JoAnne

Journal:

Year:

2007

Language:

english

File:

PDF, 452 KB

english, 2007

122

Studies of Co·Bleomycin A2 Green: Its Detailed Structural Characterization by NMR and Molecular Modeling and Its Sequence-Specific Interaction with DNA Oligonucleotides

Wu, Wei, Vanderwall, Dana E., Lui, Siu Man, Tang, Xue-Jun, Turner, Christopher J., Kozarich, John W., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 377 KB

english, 1996

123

Unmasking the chemistry of DNA cleavage by the esperamicins: modulation of 4'-hydrogen abstraction and bistranded damage by the fucose-anthranilate moiety

Christner, Donna F., Frank, Bruce L., Kozarich, John W., Stubbe, JoAnne, Golik, Jerzy, Doyle, Terrence W., Rosenberg, Ira E., Krishnan, Bala

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

124

Inactivation of Lactobacillus leichmannii Ribonucleotide Reductase by 2′,2′-Difluoro-2′-deoxycytidine 5′-Triphosphate: Adenosylcobalamin Destruction and Formation of a Nucleotide-Based Radical

Lohman, Gregory J. S., Gerfen, Gary J., Stubbe, JoAnne

Journal:

Year:

2010

Language:

english

File:

PDF, 3.11 MB

english, 2010

125

Direct EPR Spectroscopic Evidence for an Allylic Radical Generated from ( E )-2‘-Fluoromethylene-2‘-deoxycytidine 5‘-Diphosphate by E. coli Ribonucleotide Reductase

van der Donk, Wilfred A., Gerfen, Gary J., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 90 KB

english, 1998

126

Methodology To Probe Subunit Interactions in Ribonucleotide Reductases †

Hassan, A. Quamrul, Wang, Yongting, Plate, Lars, Stubbe, JoAnne

Journal:

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

127

Formal Reduction Potential of 3,5-Difluorotyrosine in a Structured Protein: Insight into Multistep Radical Transfer

Ravichandran, Kanchana R., Liang, Li, Stubbe, JoAnne, Tommos, Cecilia

Journal:

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

128

Reactions Catalyzed by 5-Aminoimidazole Ribonucleotide Carboxylases from Escherichia coli and Gallus gallus: A Case for Divergent Catalytic Mechanisms?

Firestine, Steven M., Poon, Sing-Wing, Mueller, Ernest J., Stubbe, JoAnne, Davisson, V. Jo

Journal:

Year:

1994

Language:

english

File:

PDF, 930 KB

english, 1994

129

Circular Dichroism and Magnetic Circular Dichroism Studies of the Fully Reduced Binuclear Non-Heme Iron Active Site in the Escherichia coli R2 Subunit of Ribonucleoside Diphosphate Reductase

Pulver, Sabine Coates, Tong, Wing H., Bollinger, J. Martin, Stubbe, Joanne, Solomon, Edward I.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.67 MB

english, 1995

130

Products of the inactivation of ribonucleoside diphosphate reductase from Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate

Salowe, Scott P., Ator, Mark A., Stubbe, JoAnne

Journal:

Year:

1987

Language:

english

File:

PDF, 1.15 MB

english, 1987

131

Use of 3-Aminotyrosine To Examine the Pathway Dependence of Radical Propagation in Escherichia coli Ribonucleotide Reductase

Minnihan, Ellen C., Seyedsayamdost, Mohammad R., Stubbe, JoAnne

Journal:

Year:

2009

Language:

english

File:

PDF, 2.07 MB

english, 2009

132

Enolase catalyzed βγ-αβ isomerization of 2-phospho-3-butenoic acid to (Z)-phosphoenol-α-ketobutyrate

Appelbaum, Jonathan, Stubbe, JoAnne

Journal:

Year:

1975

Language:

english

File:

PDF, 574 KB

english, 1975

133

2,3-Difluorotyrosine at Position 356 of Ribonucleotide Reductase R2: A Probe of Long-Range Proton-Coupled Electron Transfer

Yee, Cyril S., Chang,, Ge, Jie, Nocera, Daniel G., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

134

Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima: Structural Insights into Complex Formation †‡

Morar, Mariya, Hoskins, Aaron A., Stubbe, JoAnne, Ealick, Steven E.

Journal:

Year:

2008

Language:

english

File:

PDF, 14.19 MB

english, 2008

135

Site-Specific Insertion of 3-Aminotyrosine into Subunit α2 of E. coli Ribonucleotide Reductase: Direct Evidence for Involvement of Y 730 and Y 731 in Radical Propagation

Seyedsayamdost, Mohammad R., Xie, Jianming, Chan, Clement T. Y., Schultz, Peter G., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 329 KB

english, 2007

136

A non-heme iron protein with heme tendencies: An investigation of the substrate specificity of thymine hydroxylase

Thornburg, Lora D., Lai, Ming Tain, Wishnok, John S., Stubbe, JoAnne

Journal:

Year:

1993

Language:

english

File:

PDF, 1.31 MB

english, 1993

137

Acyl migration in the production of thymine. Propenal from 3'-O-benzoyl-5'-deoxy-4'-(hydroperoxy)thymidine: a reinterpretation of a putative model for bleomycin-mediated DNA degradation

McGall, Glenn H., Stubbe, JoAnne, Kozarich, John W.

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 1.02 MB

english, 1991

138

Reconsideration of X, the Diiron Intermediate Formed during Cofactor Assembly in E. coli Ribonucleotide Reductase

Sturgeon, Bradley E., Burdi, Doug, Chen, Shuxian, Huynh, Boi-Hanh, Edmondson, Dale E., Stubbe, JoAnne, Hoffman, Brian M.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 335 KB

english, 1996

139

Inactivation of Lactobacillus leichmannii Ribonucleotide Reductase by 2′,2′-Difluoro-2′-deoxycytidine 5′-Triphosphate: Covalent Modification

Lohman, Gregory J. S., Stubbe, JoAnne

Journal:

Year:

2010

Language:

english

File:

PDF, 2.73 MB

english, 2010

140

Identification of Protonated Oxygenic Ligands of Ribonucleotide Reductase Intermediate X

Shanmugam, Muralidharan, Doan, Peter E., Lees, Nicholas S., Stubbe, JoAnne, Hoffman, Brian M.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 801 KB

english, 2009

141

Inactivation of the Lactobacillus leichmannii ribonucleoside triphosphate reductase by 2'-chloro-2'-deoxyuridine 5'-triphosphate: stoichiometry of inactivation, site of inactivation, and mechanism of the protein chromophore formation

Ashley, Gary W., Harris, Georgianna, Stubbe, JoAnne

Journal:

Year:

1988

Language:

english

File:

PDF, 777 KB

english, 1988

142

Identification and quantitation of the lesion accompanying base release in bleomycin-mediated DNA degradation

Rabow, Lois E., Stubbe, JoAnne, Kozarich, John W.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

143

Definition of the Effect and Role of the Bleomycin A 2 Valerate Substituents: Preorganization of a Rigid, Compact Conformation Implicated in Sequence-Selective DNA Cleavage

Boger, Dale L., Ramsey, Timothy M., Cai, Hui, Hoehn, Silvia T., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

144

The Dimanganese(II) Site of Bacillus subtilis Class Ib Ribonucleotide Reductase

Boal, Amie K., Cotruvo, Joseph A., Stubbe, JoAnne, Rosenzweig, Amy C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

145

Solution Structure of Co·Bleomycin A2 Green Complexed with d(CCAGGCCTGG)

Wu, Wei, Vanderwall, Dana E., Turner, Christopher J., Kozarich, John W., Stubbe, JoAnne

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 328 KB

english, 1996

146

Evidence for the Direct Transfer of the Carboxylate of N 5 -Carboxyaminoimidazole Ribonucleotide ( N 5 -CAIR) To Generate 4-Carboxy-5-aminoimidazole Ribonucleotide Catalyzed by Escherichia coli PurE, an N 5 -CAIR Mutase †

Meyer, Erik, Kappock, T. Joseph, Osuji, Chukwunenye, Stubbe, JoAnne

Journal:

Year:

1999

Language:

english

File:

PDF, 134 KB

english, 1999

147

EPR Investigations of the Inactivation of E. coli Ribonucleotide Reductase with 2'-Azido-2'-deoxyuridine 5'-Diphosphate: Evidence for the Involvement of the Thiyl Radical of C225-R1

van der Donk, Wilfred A., Stubbe, JoAnne, Gerfen, Gary J., Bellew, Brendan F., Griffin, Robert G.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

148

Bacillus subtilis Class Ib Ribonucleotide Reductase Is a Dimanganese(III)-Tyrosyl Radical Enzyme

Zhang, Yan, Stubbe, JoAnne

Journal:

Year:

2011

Language:

english

File:

PDF, 2.98 MB

english, 2011

149

Mechanism of inactivation of Escherichia coli ribonucleotide reductase by 2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a 2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift

Ator, Mark A., Stubbe, JoAnne

Journal:

Year:

1985

Language:

english

File:

PDF, 1.64 MB

english, 1985

150

N5-Carboxyaminoimidazole Ribonucleotide: Evidence for a New Intermediate and Two New Enzymic Activities in the de Novo Purine Biosynthetic Pathway of Escherichia coli

Mueller, Ernest J., Meyer, Erik, Rudolph, Johannes, Davisson, V. Jo, Stubbe, JoAnne

Journal:

Year:

1994

Language:

english

File:

PDF, 1.26 MB

english, 1994