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51

Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells

Sebastian Baehs, Andreas Herbst, Susanne E. Thieme, Claudia Perschl, Andrea Behrens, Silvio Scheel, Andreas Jung, Thomas Brabletz, Burkhard Göke, Helmut Blum, Frank T. Kolligs

Journal:

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

52

The Invasion Front of Human Colorectal Adenocarcinomas Shows Co-Localization of Nuclear β-Catenin, Cyclin D1, and p16INK4A and Is a Region of Low Proliferation

Andreas Jung, Michael Schrauder, Ursula Oswald, Claudia Knoll, Petter Sellberg, Richard Palmqvist, Gerald Niedobitek, Thomas Brabletz, Thomas Kirchner

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 874 KB

english, 2001

53

Patterning and Nuclear β-Catenin Expression in the Colonic Adenoma-Carcinoma Sequence: Analogies with Embryonic Gastrulation

Thomas Kirchner, Thomas Brabletz

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 3.80 MB

english, 2000

54

Expression of Nuclear β-Catenin and c-myc Is Correlated with Tumor Size but Not with Proliferative Activity of Colorectal Adenomas

Thomas Brabletz, Kathrin Herrmann, Andreas Jung, Gerhard Faller, Thomas Kirchner

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 447 KB

english, 2000

55

β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer

Thomas Brabletz, Andreas Jung, Serpil Dag, Falk Hlubek, Thomas Kirchner

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 314 KB

english, 1999

56

Nuclear Overexpression of the Oncoprotein β-Catenin in Colorectal Cancer is Localized Predominantly at the Invasion Front

Thomas Brabletz, Andreas Jung, Kathrin Hermann, Klaus Günther, Werner Hohenberger, Thomas Kirchner

Journal:

Pathology - Research and Practice

Year:

1998

Language:

english

File:

PDF, 5.42 MB

english, 1998

57

93 MicroRNAs, EMT and Cancer Stem Cells

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 64 KB

english, 2012

58

The Microenvironment Controls CDX2 Homeobox Gene Expression in Colorectal Cancer Cells

Fairouz Benahmed, Isabelle Gross, Dominique Guenot, Frédéric Jehan, Elisabeth Martin, Claire Domon-Dell, Thomas Brabletz, Michèle Kedinger, Jean-Noël Freund, Isabelle Duluc

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 3.42 MB

english, 2007

59

EMT and MET in Metastasis: Where Are the Cancer Stem Cells?

Thomas Brabletz

Journal:

Year:

2012

Language:

english

File:

PDF, 89 KB

english, 2012

60

The transcription factor ZEB1 (δEF1) represses Plakophilin 3 during human cancer progression

Kirsten Aigner, Luise Descovich, Mario Mikula, Aneesa Sultan, Brigitta Dampier, Stefan Bonné, Frans van Roy, Wolfgang Mikulits, Martin Schreiber, Thomas Brabletz, Wolfgang Sommergruber, Norbert Schwei

Journal:

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

61

Heterogeneity among Whipple's-disease-associated bacteria

Dag Harmsen, Jürgen Heesemann, Thomas Brabletz, Thomas Kirchner, HansKonrad Müller-Hermelink

Journal:

Year:

1994

Language:

english

File:

PDF, 153 KB

english, 1994

62

Detection of disseminated tumour cells in mediastinoscopic lymph node biopsies and endobronchial ultrasonography-guided transbronchial needle aspiration in patients with suspected lung cancer

Dango, S., Cucuruz, B., Mayer, O., Brabletz, S., Follo, M., Elze, M., Sienel, W., Brabletz, T., Passlick, B.

Journal:

Year:

2010

Language:

english

File:

PDF, 253 KB

english, 2010

63

43 Different Candidate Genes and Their Role During Tumor Progression, Invasion and Metastasis

Heike Kunert, Sarah Hauss, Claus W. Franzke, Nina Hirt, Angela Queisser, Falk Mancke, Thomas Reinheckel, Leena Bruckner-Tudermann, Thomas Brabletz, Christoph Peters, Oliver G. Opitz

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

64

A Transient, EMT-Linked Loss of Basement Membranes Indicates Metastasis and Poor Survival in Colorectal Cancer

Simone Spaderna, Otto Schmalhofer, Falk Hlubek, Geert Berx, Andreas Eger, Susanne Merkel, Andreas Jung, Thomas Kirchner, Thomas Brabletz

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 2.95 MB

english, 2006

65

Precancerous Lesions Upon Sporadic Activation of β-Catenin in Mice

Isabelle Coste, Jean–Noël Freund, Simone Spaderna, Thomas Brabletz, Toufic Renno

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 7.39 MB

english, 2007

66

Predictive Molecular Markers for Colorectal Cancer Patients With Resected Liver Metastasis and Adjuvant Chemotherapy

Silke Lassmann, Laura Tang, Marinela Capanu, Thomas Brabletz, Anja Schöpflin, Axel Zur Hausen, Mithat Gonen, Nancy Kemeny, Jinru Shia, David Klimstra, Martin Werner

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 864 KB

english, 2007

67

p16INK4a Is a β-Catenin Target Gene and Indicates Low Survival in Human Colorectal Tumors

Stella Wassermann, Silvio K. Scheel, Elke Hiendlmeyer, Richard Palmqvist, David Horst, Falk Hlubek, Angela Haynl, Lydia Kriegl, Simone Reu, Susanne Merkel, Thomas Brabletz, Thomas Kirchner, Andreas Ju

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 1.98 MB

english, 2009

68

The miR-200 Family: Central Player for Gain and Loss of the Epithelial Phenotype

Simone Spaderna, Thomas Brabletz, Oliver G. Opitz

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

69

A Human Three-Dimensional Cell Line Model Allows the Study of Dynamic and Reversible Epithelial-Mesenchymal and Mesenchymal-Epithelial Transition That Underpins Colorectal Carcinogenesis

Vincan, Elizabeth, Brabletz, Thomas, Faux, Maree C., Ramsay, Robert G.

Journal:

Cells Tissues Organs

Year:

2007

Language:

english

File:

PDF, 546 KB

english, 2007

70

Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors

Jaitner, Stefanie, Reiche, Jana A., Schäffauer, Achim J., Hiendlmeyer, Elke, Herbst, Hermann, Brabletz, Thomas, Kirchner, Thomas, Jung, Andreas

Journal:

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

71

Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-κB signaling that promotes colon cancer progression

Ben-Shmuel, A, Shvab, A, Gavert, N, Brabletz, T, Ben-Ze'ev, A

Journal:

Year:

2013

Language:

english

File:

PDF, 8.86 MB

english, 2013

72

Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency

Bedzhov, Ivan, Alotaibi, Hani, Basilicata, M. Felicia, Ahlborn, Kerstin, Liszewska, Ewa, Brabletz, Thomas, Stemmler, Marc P.

Journal:

Stem Cell Research

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

73

Roadblocks to translational advances on metastasis research

Brabletz, Thomas, Lyden, David, Steeg, Patricia S, Werb, Zena

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 342 KB

english, 2013

74

A p21-ZEB1 Complex Inhibits Epithelial-Mesenchymal Transition through the MicroRNA 183-96-182 Cluster

Li, X. L., Hara, T., Choi, Y., Subramanian, M., Francis, P., Bilke, S., Walker, R. L., Pineda, M., Zhu, Y., Yang, Y., Luo, J., Wakefield, L. M., Brabletz, T., Park, B. H., Sharma, S., Chowdhury, D., M

Journal:

Molecular and Cellular Biology

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

75

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

Spaderna, S., Schmalhofer, O., Wahlbuhl, M., Dimmler, A., Bauer, K., Sultan, A., Hlubek, F., Jung, A., Strand, D., Eger, A., Kirchner, T., Behrens, J., Brabletz, T.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 839 KB

english, 2008

76

Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer

Bronsert, Peter, Kohler, Ilona, Timme, Sylvia, Kiefer, Selina, Werner, Martin, Schilling, Oliver, Vashist, Yogesh, Makowiec, Frank, Brabletz, Thomas, Hopt, Ulrich T., Bausch, Dirk, Kulemann, Birte, Ke

Journal:

Year:

2014

Language:

english

File:

PDF, 499 KB

english, 2014

77

Cloning of a cDNA coding for the Acetylcholine Receptor α-Subunit from a Thymoma associated with Myasthenia Gravis

Brabletz, T., Gattenlöhner, S., Marx, A., Müller-Hermelink, H.K., Kirchner, T.

Journal:

Neuromuscular Disorders

Year:

1994

Language:

english

File:

PDF, 74 KB

english, 1994

78

Molecules of thymocyte-stroma-interaction in thymoma: The thymus-like pattern as a prerequisite for an abnormal T cell selection in praneoplastic myasthenia gravis

Marx, A., Schömig, Doris, Jung, A., Schultz, Anja, Gattenlöhner, S., Brabletz, Th., Kirchner, Th., Müller-Hermelink, H.K.

Journal:

Neuromuscular Disorders

Year:

1994

Language:

english

File:

PDF, 74 KB

english, 1994

79

DNA mismatch repair deficiency is associated with improved prognosis in patients with curatively resected adenocarcinoma of the small intestine

Brueckl, Wolfgang M., Milsmann, Catrin, Wein, Axel, Reingruber, Bertram, Boxberger, Frank, Heinze, Elvira, Brabletz, Thomas, Hohenberger, Werner, Becker, Heinz, Hahn, Eckhart G.

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

80

Palliative chemotherapy in colorectal cancer: Microsatellite instability and its correlation with response and survival

Brueckl, Wolfgang M., Wein, Axel, Moesch, Christian, Brabletz, Thomas, Radespiel-Troeger, Martin, Riedel, Christian, Hanke, Bert, Guenther, Klaus, Wiest, Gunther H., Kirchner, Thomas, Hohenberger, Wer

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

81

T1177 Tumor Progression, Invasion and Metastasis in a Genetically Defined Model of Esophageal Squamous Carcinogenesis

Kunert, Heike, Hauss, Sarah, Queisser, Angela, Reinheckel, Thomas, Bruckner-Tudermann, Leena, Peters, Christoph, Brabletz, Thomas, Opitz, Oliver G.

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

82

Mismatch repair defficiency is associated with a better response and a longer survival time in patients with metastatic colorectal cancer receiving first-line chemotherapy

Brueckl, Wolfgang M., Wein, Axel, Moesch, Christian, Schaber, Stetan, Jung, Andreas, Brabletz, Thomas, Boxberger, Frank, Guenther, Klaus, Wiest, Gunther H., Kirchner, Thomas, Hohenberger, Werner, Hahn

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

83

Oncogenic roles of EMT-inducing transcription factors

Puisieux, Alain, Brabletz, Thomas, Caramel, Julie

Journal:

Nature Cell Biology

Year:

2014

Language:

english

File:

PDF, 822 KB

english, 2014

84

L1, a Novel Target of β-catenin Signaling, Transforms Cells and Is Expressed at the Invasive Front of Colon Cancers

Nancy Gavert, Maralice Conacci-Sorrell, Daniela Gast, Annette Schneider, Peter Altevogt, Thomas Brabletz and Avri Ben-Zéev

Journal:

The Journal of Cell Biology

Year:

2005

Language:

english

File:

PDF, 3.04 MB

english, 2005

85

Zeb1 Regulates E-cadherin and Epcam (Epithelial Cell Adhesion Molecule) Expression to Control Cell Behavior in Early Zebrafish Development

Vannier, C., Mock, K., Brabletz, T., Driever, W.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 6.32 MB

english, 2013

86

DNA Loops Induced by Cooperative Binding of Transcriptional Activator Proteins and Preinitiation Complexes

Jurgen C. Becker, Abbas Nikroo, Thomas Brabletz and Ralph A. Reisfeld

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.09 MB

english, 1995

87

Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma

Hlubek, F, Pfeiffer, S, Budczies, J, Spaderna, S, Jung, A, Kirchner, T, Brabletz, T

Journal:

British Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

88

Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition

Alotaibi, Hani, Basilicata, M. Felicia, Shehwana, Huma, Kosowan, Tyler, Schreck, Ilona, Braeutigam, Christien, Konu, Ozlen, Brabletz, Thomas, Stemmler, Marc P.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2015

Language:

english

File:

PDF, 2.62 MB

english, 2015

89

L1-Mediated Colon Cancer Cell Metastasis Does Not Require Changes in EMT and Cancer Stem Cell Markers

Gavert, N., Vivanti, A., Hazin, J., Brabletz, T., Ben-Ze'ev, A.

Journal:

Molecular Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

90

The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer

Brabletz, Thomas, Pietrowski, Ilona, Serfling, Edgar

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 3.06 MB

english, 1991

91

Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma

Kohler, Ilona, Bronsert, Peter, Timme, Sylvia, Werner, Martin, Brabletz, Thomas, Hopt, Ulrich Theodor, Schilling, Oliver, Bausch, Dirk, Keck, Tobias, Wellner, Ulrich Friedrich

Journal:

Journal of Gastroenterology and Hepatology

Year:

2015

Language:

english

File:

PDF, 349 KB

english, 2015

92

Down-Regulation of the Homeodomain Factor Cdx2 in Colorectal Cancer by Collagen Type I: An Active Role for the Tumor Environment in Malignant Tumor Progression

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 596 KB

english, 2004

93

DRO1, a Gene Down-regulated by Oncogenes, Mediates Growth Inhibition in Colon and Pancreatic Cancer Cells

Bommer, G. T., Jager, C., Durr, E.-M., Baehs, S., Eichhorst, S. T., Brabletz, T., Hu, G., Frohlich, T., Arnold, G., Kress, D. C., Goke, B., Fearon, E. R., Kolligs, F. T.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.45 MB

english, 2005

94

Nuclear factor- B signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells

Gavert, N., Ben-Shmuel, A., Lemmon, V., Brabletz, T., Ben-Ze'ev, A.

Journal:

Journal of Cell Science

Year:

2010

Language:

english

File:

PDF, 3.44 MB

english, 2010

95

Variable -catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

Brabletz, T., Jung, A., Reu, S., Porzner, M., Hlubek, F., Kunz-Schughart, L. A., Knuechel, R., Kirchner, T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 1.62 MB

english, 2001

96

Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression

Shvab, A, Haase, G, Ben-Shmuel, A, Gavert, N, Brabletz, T, Dedhar, S, Ben-Ze'ev, A

Journal:

Year:

2015

Language:

english

File:

PDF, 2.76 MB

english, 2015

97

Generation and Characterization of Human Monoclonal scFv Antibodies against Helicobacter pylori Antigens

Reiche, N., Jung, A., Brabletz, T., Vater, T., Kirchner, T., Faller, G.

Journal:

Infection and Immunity

Year:

2002

Language:

english

File:

PDF, 1010 KB

english, 2002

98

ZEB1 in Pancreatic Cancer

Wellner, Ulrich, Brabletz, Thomas, Keck, Tobias

Journal:

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

99

Tumor escape mechanisms from immunosurveillance: induction of unresponsiveness in a specific MHC-restricted CD4 + ; human T cell clone by the autologous MHC class II + melanoma

Becker, J. C., Brabletz, T., Czerny, C., Termeer, C., Bröcker, E. B.

Journal:

International Immunology

Year:

1993

Language:

english

File:

PDF, 3.29 MB

english, 1993

100

Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB

Brabletz, T., Jung, A., Hlubek, F., Lohberg, C., Meiler, J., Suchy, U., Kirchner, T.

Journal:

International Immunology

Year:

1999

Language:

english

File:

PDF, 293 KB

english, 1999