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51

MCT1-Mediated Transport of L-Lactic Acid at the Inner Blood–Retinal Barrier: A Possible Route for Delivery of Monocarboxylic Acid Drugs to the Retina

Ken-ichi Hosoya, Tetsu Kondo, Masatoshi Tomi, Hitomi Takanaga, Sumio Ohtsuki, Tetsuya Terasaki

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 293 KB

english, 2001

52

Stereoselective and Carrier-Mediated Transport of Monocarboxylic Acids Across Caco-2 Cells

Takuo Ogihara, Ikumi Tamai, Hitomi Takanaga, Yoshimichi Sai, Akira Tsuji

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 921 KB

1996

53

Effects of Grapefruit Juice and Orange Juice on the Intestinal Efflux of P-Glycoprotein Substrates

Run Tian, Noriko Koyabu, Hitomi Takanaga, Hirotami Matsuo, Hisakazu Ohtani, Yasufumi Sawada

Journal:

Pharmaceutical Research

Year:

2002

Language:

english

File:

PDF, 163 KB

english, 2002

54

Proton-Cotransport of Pravastatin Across Intestinal Brush-Border Membrane

Ikumi Tamai, Hitomi Takanaga, Hiroshi Maeda, Takuo Ogihara, Masaru Yoneda, Akira Tsuji

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.14 MB

1995

55

Transcellular Transport of Benzole Acid Across Caco-2 Cells by a pH-Dependent and Carrier-Mediated Transport Mechanism

Akira Tsuji, Hitomi Takanaga, Ikumi Tamai, Tetsuya Terasaki

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.63 MB

1994

56

Choline Uptake by Mouse Brain Capillary Endothelial Cells in Culture

Naoyuki Sawada, Hitomi Takanaga, Hirotami Matsuo, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

57

Immunohistochemical and Functional Characterization of pH-dependent Intestinal Absorption of Weak Organic Acids by the Monocarboxylic Acid Transporter MCT1

IKUMI TAMAI, YOSHIMICHI SAI, AKIHIKO ONO, YASUTO KIDO, HIKARU YABUUCHI, HITOMI TAKANAGA, EIKO SATOH, TAKUO OGIHARA, OSAMU AMANO, SHOICHI IZEKI, AKIRA TSUJI

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 329 KB

english, 1999

58

Gli2 Is a Novel Regulator of Sox2 Expression in Telencephalic Neuroepithelial Cells

Hiromi Takanaga, Nobuko Tsuchida-Straeten, Kenji Nishide, Akira Watanabe, Hiroyuki Aburatani, Toru Kondo

Journal:

Year:

2009

Language:

english

File:

PDF, 1.64 MB

english, 2009

59

Xenopus PKN: cloning and sequencing of the cDNA and identification of conserved domains

Hideyuki Mukai, Kazuya Mori, Hiromi Takanaga, Michinori Kitagawa, Hideki Shibata, Masaki Shimakawa, Masako Miyahara, Yoshitaka Ono

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1995

Language:

english

File:

PDF, 431 KB

english, 1995

60

Distribution and ultrastructure of dopaminergic neurons in the dorsal motor nucleus of the vagus projecting to the stomach of the rat

Tetsu Hayakawa, Akinori Takanaga, Koichi Tanaka, Seishi Maeda, Makoto Seki

Journal:

Year:

2004

Language:

english

File:

PDF, 580 KB

english, 2004

61

Ultrastructure of the rostral ventral respiratory group neurons in the ventrolateral medulla of the rat

Tetsu Hayakawa, Akinori Takanaga, Koichi Tanaka, Seishi Maeda, Makoto Seki

Journal:

Year:

2004

Language:

english

File:

PDF, 692 KB

english, 2004

62

α-Synuclein-positive structures induced in leupeptin-infused rats

T. Nakajima, S. Takauchi, K. Ohara, M. Kokai, R. Nishii, S. Maeda, A. Takanaga, T. Tanaka, M. Takeda, M. Seki, Y. Morita

Journal:

Year:

2005

Language:

english

File:

PDF, 536 KB

english, 2005

63

Osmotic induction of calcium accumulation in human embryonic kidney cells detected with a high sensitivity FRET calcium sensor

Bi-Huei Hou, Hitomi Takanaga, Oliver Griesbeck, Wolf B. Frommer

Journal:

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

64

Fluxomics: mass spectrometry versus quantitative imaging

Wolfgang Wiechert, Oliver Schweissgut, Hitomi Takanaga, Wolf B Frommer

Journal:

Current Opinion in Plant Biology

Year:

2007

Language:

english

File:

PDF, 587 KB

english, 2007

65

Effect of bioflavonoids on vincristine transport across blood–brain barrier

Yoshiharu Mitsunaga, Hitomi Takanaga, Hirotami Matsuo, Mikihiko Naito, Takashi Tsuruo, Hisakazu Ohtani, Yasufumi Sawada

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 414 KB

english, 2000

66

Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein

Fumihiko Ushigome, Hitomi Takanaga, Hirotami Matsuo, Shigeaki Yanai, Kiyomi Tsukimori, Hitoo Nakano, Takeshi Uchiumi, Takanori Nakamura, Michihiko Kuwano, Hisakazu Ohtani, Yasufumi Sawada

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 381 KB

english, 2000

67

Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo)

Fumihiko Ushigome, Hitomi Takanaga, Hirotami Matsuo, Kiyomi Tsukimori, Hitoo Nakano, Hisakazu Ohtani, Yasufumi Sawada

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 146 KB

english, 2001

68

Effect of cyclosporin A or tacrolimus on the function of blood–brain barrier cells

Satoko Kochi, Hitomi Takanaga, Hirotami Matsuo, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 301 KB

english, 1999

69

Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein

Hirotami Matsuo, Masahiro Wakasugi, Hitomi Takanaga, Hisakazu Ohtani, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

Journal of Controlled Release

Year:

2001

Language:

english

File:

PDF, 451 KB

english, 2001

70

New approaches to in vitro models of blood–brain barrier drug transport

Tetsuya Terasaki, Sumio Ohtsuki, Satoko Hori, Hitomi Takanaga, Emi Nakashima, Ken-ichi Hosoya

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

71

Activation of PKN, a Novel 120-kDa Protein Kinase with Leucine Zipper-like Sequences, by Unsaturated Fatty Acids and by Limited Proteolysis

H. Mukai, M. Kitagawa, H. Shibata, H. Takanaga, K. Mori, M. Shimakawa, M. Miyahara, K. Hirao, Y. Ono

Journal:

Biochemical and Biophysical Research Communications

Year:

1994

File:

PDF, 433 KB

1994

72

Participation of a Proton-Cotransporter, MCT1, in the Intestinal Transport of Monocarboxylic Acids

I. Tamai, H. Takanaga, T. Ogihara, H. Higashida, H. Maeda, Y. Sai, A. Tsuji

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 412 KB

1995

73

cDNA Cloning and Functional Characterization of Rat Intestinal Monocarboxylate Transporter

H. Takanaga, I. Tamai, S. Inaba, Y. Sai, H. Higashida, H. Yamamoto, A. Tsuji

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 476 KB

1995

74

PKN Interacts with a Paraneoplastic Cerebellar Degeneration-Associated Antigen, Which Is a Potential Transcription Factor

Hiromi Takanaga, Hideyuki Mukai, Hideki Shibata, Masanao Toshimori, Yoshitaka Ono

Journal:

Experimental Cell Research

Year:

1998

Language:

english

File:

PDF, 703 KB

english, 1998

75

Conditionally Immortalized Retinal Capillary Endothelial Cell Lines (TR-iBRB) Expressing Differentiated Endothelial Cell Functions Derived from a Transgenic Rat

Ken-Ichi Hosoya, Masatoshi Tomi, Sumio Ohtsuki, Hitomi Takanaga, Masatsugu Ueda, Nobuaki Yanai, Masuo Obinata, Tetsuya Terasaki

Journal:

Experimental Eye Research

Year:

2001

Language:

english

File:

PDF, 431 KB

english, 2001

76

In Vivo Evidence for Brain-to-Blood Efflux Transport of Valproic Acid across the Blood–Brain Barrier

Atsuyuki Kakee, Hitomi Takanaga, Ken-ichi Hosoya, Yuichi Sugiyama, Tetsuya Terasaki

Journal:

Microvascular Research

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

77

Functional characterization of the promoter region of the mouse protein kinase C γ gene

Hiromi Takanaga, Hideyuki Mukai, Masaki Shimakawa, Hiroaki Konishi, Ushio Kikkawa, Tamio Koizumi, Yoshitaka Ono

Journal:

Year:

1995

Language:

english

File:

PDF, 344 KB

english, 1995

78

Identification of Schizosaccharomyces pombe gene pskl+, encoding a novel putative serine/threonine protein kinase, whose mutation conferred resistance to phenylarsine oxide

Hideyuki Mukai, Masako Miyahara, Hiromi Takanaga, Michinori Kitagawa, Hideki Shibata, Masaki Shimakawa, Yoshitaka Ono

Journal:

Year:

1995

Language:

english

File:

PDF, 466 KB

english, 1995

79

GLUT1 and GLUT9 as major contributors to glucose influx in HepG2 cells identified by a high sensitivity intramolecular FRET glucose sensor

Hitomi Takanaga, Bhavna Chaudhuri, Wolf B. Frommer

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

80

Characterization of the organic cation transporter SLC22A16: A doxorubicin importer

Mitsunori Okabe, Michiaki Unno, Hideo Harigae, Mitsuo Kaku, Yoko Okitsu, Takeshi Sasaki, Takayuki Mizoi, Kenichi Shiiba, Hitomi Takanaga, Tetsuya Terasaki, Seiki Matsuno, Iwao Sasaki, Sadayoshi Ito, T

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 539 KB

english, 2005

81

Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain

Hitomi Takanaga, Bryan Mackenzie, Ji-Bin Peng, Matthias A. Hediger

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 431 KB

english, 2005

82

A method of clustering observers with different visual characteristics

Takanaga Niimi, Kuniharu Imai, Mitsuru Ikeda, Hisatoshi Maeda

Journal:

European Journal of Radiology

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

83

Information loss in visual assessments of medical images

Takanaga Niimi, Kuniharu Imai, Hisatoshi Maeda, Mitsuru Ikeda

Journal:

European Journal of Radiology

Year:

2007

Language:

english

File:

PDF, 450 KB

english, 2007

84

Fractal-feature distance as a substitute for observer performance index in contrast-detail examination

Kuniharu Imai, Mitsuru Ikeda, Yukihiro Enchi, Takanaga Niimi

Journal:

European Journal of Radiology

Year:

2008

Language:

english

File:

PDF, 307 KB

english, 2008

85

Quantitative assessment of the influence of anatomic noise on the detection of subtle lung nodule in digital chest radiography using fractal-feature distance

Kuniharu Imai, Mitsuru Ikeda, Yukihiro Enchi, Takanaga Niimi

Journal:

European Journal of Radiology

Year:

2008

Language:

english

File:

PDF, 584 KB

english, 2008

86

P45: Diurnal rhythmicity of ileal transporter expression

A. Balakrishnan, A. Tavakkolizadeh, M. Hediger, H. Takanaga, D. Rhoads, S.W. Ashley

Journal:

Journal of Surgical Research

Year:

2007

Language:

english

File:

PDF, 212 KB

english, 2007

87

Heparan sulfate function in limb synovial joint formation

Christina Matticola, Kevin Quann, Takanaga Ochiai, Yu Yamaguchi, Eiki Koyama, Maurizio Pacifici

Journal:

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

88

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis

Eiki Koyama, Yoshihiro Shibukawa, Motohiko Nagayama, Hiroki Sugito, Blanche Young, Takahito Yuasa, Takahiro Okabe, Takanaga Ochiai, Nobuhiko Kamiya, Ryan B. Rountree, David M. Kingsley, Masahiro Iwamo

Journal:

Developmental Biology

Year:

2008

Language:

english

File:

PDF, 2.87 MB

english, 2008

89

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse

Julie A. Williams, Naoki Kondo, Takahiro Okabe, Nobuo Takeshita, Diane M. Pilchak, Eiki Koyama, Takanaga Ochiai, Deborah Jensen, Mon-Li Chu, Maureen A. Kane, Joseph L. Napoli, Motomi Enomoto-Iwamoto,

Journal:

Developmental Biology

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

90

Anion antiport mechanism is involved in transport of lactic acid across intestinal epithelial brush-border membrane

Ikumi Tamai, Takuo Ogihara, Hitomi Takanaga, Hiroshi Maeda, Akira Tsuji

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2000

Language:

english

File:

PDF, 199 KB

english, 2000

91

Induction of apoptosis in mouse brain capillary endothelial cells by cyclosporin a and tacrolimus

Satoko Kochi, Hitomi Takanaga, Hirotami Matsuo, Hisakazu Ohtani, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

Year:

2000

Language:

english

File:

PDF, 474 KB

english, 2000

92

Subnuclear distribution of afferents from the oral, pharyngeal and laryngeal regions in the nucleus tractus solitarii of the rat: a study using transganglionic transport of cholera toxin

Tetsu Hayakawa, Akinori Takanaga, Seishi Maeda, Makoto Seki, Yukio Yajima

Journal:

Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 1.81 MB

english, 2001

93

Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells

Kentaro Wakayama, Sumio Ohtsuki, Hitomi Takanaga, Ken-ichi Hosoya, Tetsuya Terasaki

Journal:

Neuroscience Research

Year:

2002

Language:

english

File:

PDF, 545 KB

english, 2002

94

The intrinsic origin of nitric oxide synthase immunoreactive nerve fibers in the right atrium of the guinea pig

Koichi Tanaka, Akinori Takanaga, Tetsu Hayakawa, Seishi Maeda, Makoto Seki

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 384 KB

english, 2001

95

A novel monoclonal antibody recognizes lysosome-like structures and reflects regional and age-related differences in the rat dentate gyrus

Seishi Maeda, Keigo Kawabata, Akinori Takanaga, Koichi Tanaka, Hisao Ito, Tetsu Hayakawa, Makoto Seki

Journal:

Neuroscience Letters

Year:

2002

Language:

english

File:

PDF, 255 KB

english, 2002

96

Immunohistochemical characterization of cardiac vagal preganglionic neurons in the rat

Akinori Takanaga, Tetsu Hayakawa, Koichi Tanaka, Keigo Kawabata, Seishi Maeda, Makoto Seki

Journal:

Autonomic Neuroscience

Year:

2003

Language:

english

File:

PDF, 423 KB

english, 2003

97

Effect of Triazole Antifungal Agents on the Drug Secretion Process in Rat Small Intestine: Contribution of P-glycoprotein

Naoyuki Sawada, Takahiro Uchida, Hirotami Matsuo, Hitomi Takanaga, Yasufumi Sawada

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 232 KB

english, 1996

98

Nicotinic Acid Transport Mediated by pH-dependent Anion Antiporter and Proton Cotransporter in Rabbit Intestinal Brush-border Membrane

Hitomi Takanaga, Hiroshi Maeda, Hikaru Yabuuchi, Ikumi Tamai, Haruhiro Higashida, Akira Tsuji

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 544 KB

english, 1996

99

Intestinal Brush-border Membrane Transport of Monocarboxylic Acids Mediated by Proton-coupled Transport and Anion Antiport Mechanisms

IKUMI TAMAI, HITOMI TAKANAGA, HIROSHI MAEDA, HIKARU YABUUCHI, YOSHIMICHI SAI, YUICHI SUZUKI, AKIRA TSUJI

Journal:

Journal of Pharmacy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 538 KB

english, 1997

100

Efflux Transport of Tolbutamide Across the Blood-brain Barrier

Hitomi Takanaga, Hideyasu Murakami, Noriko Koyabu, Hirotami Matsuo, Mikihiko Naito, Takashi Tsuruo, Yasufumi Sawada

Journal:

Journal of Pharmacy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 675 KB

english, 1998