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51

Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs

Gunter Meister, Markus Landthaler, Agnieszka Patkaniowska, Yair Dorsett, Grace Teng, Thomas Tuschl

Journal:

Year:

2004

Language:

english

File:

PDF, 362 KB

english, 2004

52

Crystal Structure of A. aeolicus Argonaute, a Site-Specific DNA-Guided Endoribonuclease, Provides Insights into RISC-Mediated mRNA Cleavage

Yu-Ren Yuan, Yi Pei, Jin-Biao Ma, Vitaly Kuryavyi, Maria Zhadina, Gunter Meister, Hong-Ying Chen, Zbigniew Dauter, Thomas Tuschl, Dinshaw J. Patel

Journal:

Year:

2005

Language:

english

File:

PDF, 1.20 MB

english, 2005

53

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

Neelanjan Mukherjee, David L. Corcoran, Jeffrey D. Nusbaum, David W. Reid, Stoyan Georgiev, Markus Hafner, Manuel Ascano Jr., Thomas Tuschl, Uwe Ohler, Jack D. Keene

Journal:

Year:

2011

Language:

english

File:

PDF, 845 KB

english, 2011

54

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

Priyamvada Rajasethupathy, Ferdinando Fiumara, Robert Sheridan, Doron Betel, Sathyanarayanan V. Puthanveettil, James J. Russo, Chris Sander, Thomas Tuschl, Eric Kandel

Journal:

Year:

2009

Language:

english

File:

PDF, 1.44 MB

english, 2009

55

Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing

Markus Hafner, Pablo Landgraf, Janos Ludwig, Amanda Rice, Tolulope Ojo, Carolina Lin, Daniel Holoch, Cindy Lim, Thomas Tuschl

Journal:

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

56

Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi

Javier Martinez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Lührmann, Thomas Tuschl

Journal:

Year:

2002

Language:

english

File:

PDF, 510 KB

english, 2002

57

Analysis of gene function in somatic mammalian cells using small interfering RNAs

Sayda M. Elbashir, Jens Harborth, Klaus Weber, Thomas Tuschl

Journal:

Year:

2002

Language:

english

File:

PDF, 772 KB

english, 2002

58

The Small RNA Profile during Drosophila melanogaster Development

Alexei A. Aravin, Mariana Lagos-Quintana, Abdullah Yalcin, Mihaela Zavolan, Debora Marks, Ben Snyder, Terry Gaasterland, Jutta Meyer, Thomas Tuschl

Journal:

Developmental Cell

Year:

2003

Language:

english

File:

PDF, 1.10 MB

english, 2003

59

MicroRNA-Mediated Down-Regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg Cells: A Potential Pathogenetic Lesion in Hodgkin Lymphomas

Kui Nie, Mario Gomez, Pablo Landgraf, Jose-Francisco Garcia, Yifang Liu, Leonard H.C. Tan, Amy Chadburn, Thomas Tuschl, Daniel M. Knowles, Wayne Tam

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 848 KB

english, 2008

60

Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype

Erin Connolly, Margherita Melegari, Pablo Landgraf, Tatyana Tchaikovskaya, Bud C. Tennant, Betty L. Slagle, Leslie E. Rogler, Mihaela Zavolan, Thomas Tuschl, Charles E. Rogler

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 557 KB

english, 2008

61

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

Zhang, Xin, Yalcin, Safak, Lee, Dung-Fang, Yeh, Tsung-Yin J., Lee, Seung-Min, Su, Jie, Mungamuri, Sathish Kumar, Rimmelé, Pauline, Kennedy, Marion, Sellers, Rani, Landthaler, Markus, Tuschl, Thomas, C

Journal:

Nature Cell Biology

Year:

2011

Language:

english

File:

PDF, 905 KB

english, 2011

62

Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing

Thalia A. Farazi, Miguel Brown, Pavel Morozov, Jelle J. ten Hoeve, Iddo Z. Ben-Dov, Volker Hovestadt, Markus Hafner, Neil Renwick, Aleksandra Mihailović, Lodewyk F.A. Wessels, Thomas Tuschl

Journal:

Year:

2012

Language:

english

File:

PDF, 2.23 MB

english, 2012

63

Genome-wide identification of miRNA targets by PAR-CLIP

Markus Hafner, Steve Lianoglou, Thomas Tuschl, Doron Betel

Journal:

Year:

2012

Language:

english

File:

PDF, 544 KB

english, 2012

64

Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing

Markus Hafner, Neil Renwick, Thalia A. Farazi, Aleksandra Mihailović, John T.G. Pena, Thomas Tuschl

Journal:

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

65

Reactions of phosphate and phosphorothiolate diesters with nucleophiles: comparison of transition state structures

Ye, Jing-Dong, Barth, Christofer D., Anjaneyulu, Potluri S. R., Tuschl, Thomas, Piccirilli, Joseph A.

Journal:

Organic & Biomolecular Chemistry

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

66

MicroRNA targets inDrosophila

Anton J Enright, Bino John, Ulrike Gaul, Thomas Tuschl, Chris Sander, Debora S Marks

Journal:

Year:

2003

Language:

english

File:

PDF, 516 KB

english, 2003

67

Multi-disciplinary methods to define RNA–protein interactions and regulatory networks

Ascano, Manuel, Gerstberger, Stefanie, Tuschl, Thomas

Journal:

Current Opinion in Genetics & Development

Year:

2013

Language:

english

File:

PDF, 2.05 MB

english, 2013

68

Isoguanosine Substitution of Conserved Adenosines in the Hammerhead Ribozyme

Ng, Mabel M. P., Benseler, Fritz, Tuschl, Thomas, Eckstein, Fritz

Journal:

Year:

1994

Language:

english

File:

PDF, 1.74 MB

english, 1994

69

A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells

Fritz, Eric L, Rosenberg, Brad R, Lay, Kenneth, Mihailović, Aleksandra, Tuschl, Thomas, Papavasiliou, F Nina

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 914 KB

english, 2013

70

Correction: Human MicroRNA Targets

John, Bino, Enright, Anton J., Aravin, Alexei, Tuschl, Thomas, Sander, Chris, Marks, Debora S.

Journal:

Year:

2005

Language:

english

File:

PDF, 29 KB

english, 2005

71

Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity

Nakanishi, Kotaro, Ascano, Manuel, Gogakos, Tasos, Ishibe-Murakami, Satoko, Serganov, Artem A., Briskin, Daniel, Morozov, Pavel, Tuschl, Thomas, Patel, Dinshaw J.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.31 MB

english, 2013

72

MicroRNAs that silence tau expression are dysregulated in Alzheimer's disease

Santa-Maria, Ismael, Alaniz, Maria Eugenia, Renwick, Neil, Tuschl, Thomas, Clark, Lorraine, Crary, John

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 50 KB

english, 2013

73

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis

Cheung, Irene Y., Farazi, Thalia A., Ostrovnaya, Irina, Xu, Hong, Tran, Hoa, Mihailovic, Aleksandra, Tuschl, Thomas, Cheung, Nai-Kong V.

Journal:

Genes, Chromosomes and Cancer

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

74

Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. [Erratum to document cited in CA119(23):244321x]

Tuschl, Thomas, Ng, Mabel M. P., Pieken, Wolfgang, Benseler, Fritiz, Eckstein, Fritz

Journal:

Year:

1994

Language:

english

File:

PDF, 70 KB

english, 1994

75

RNA targets of wild-type and mutant FET family proteins

Hoell, Jessica I, Larsson, Erik, Runge, Simon, Nusbaum, Jeffrey D, Duggimpudi, Sujitha, Farazi, Thalia A, Hafner, Markus, Borkhardt, Arndt, Sander, Chris, Tuschl, Thomas

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 586 KB

english, 2011

76

Mg 2+ -Dependent Conformational Changes in the Hammerhead Ribozyme †

Menger, Marcus, Tuschl, Thomas, Eckstein, Fritz, Porschke, Dietmar

Journal:

Year:

1996

Language:

english

File:

PDF, 374 KB

english, 1996

77

Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity

Tuschl, Thomas, Ng, Mabel M. P., Pieken, Wolfgang, Benseler, Fritz, Eckstein, Fritz

Journal:

Year:

1993

Language:

english

File:

PDF, 2.68 MB

english, 1993

78

A census of human RNA-binding proteins

Gerstberger, Stefanie, Hafner, Markus, Tuschl, Thomas

Journal:

Nature Reviews Genetics

Year:

2014

Language:

english

File:

PDF, 4.75 MB

english, 2014

79

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

Gao, Pu, Zillinger, Thomas, Wang, Weiyi, Ascano, Manuel, Dai, Peihong, Hartmann, Gunther, Tuschl, Thomas, Deng, Liang, Barchet, Winfried, Patel, Dinshaw J.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.30 MB

english, 2014

80

Activity of hammerhead ribozymes containing nonnucleotidic linkers

Thomson, James B., Tuschl, Thomas, Eckstein, Fritz

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 1.62 MB

english, 1993

81

Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets

Farazi, Thalia A, ten Hoeve, Jelle J, Brown, Miguel, Mihailovic, Aleksandra, Horlings, Hugo M, van de Vijver, Marc J, Tuschl, Thomas, Wessels, Lodewyk FA

Journal:

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

82

Oligonucleotide duplexes containing 2′-amino-2′-deoxycytidines: thermal stability and chemical reactivity

Aurup, Helle, Tuschl, Thomas, Benseler, Fritz, Ludwig, Janos, Eckstein, Fritz

Journal:

Nucleic Acids Research

Year:

1994

Language:

english

File:

PDF, 514 KB

english, 1994

83

Human MicroRNA Targets

John, Bino, Enright, Anton J., Aravin, Alexei, Tuschl, Thomas, Sander, Chris, Marks, Debora S.

Journal:

Year:

2004

Language:

english

File:

PDF, 42 KB

english, 2004

84

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

Latreille, Mathieu, Herrmanns, Karolin, Renwick, Neil, Tuschl, Thomas, Malecki, Maciej T., McCarthy, Mark I., Owen, Katharine R., Rülicke, Thomas, Stoffel, Markus

Journal:

Journal of Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

85

Decreased Follicular Phase Gonadotropin Secretion Is Associated with Impaired Estradiol and Progesterone Secretion during the Follicular and Luteal Phases in Normally Menstruating Women*

SCHWEIGER, ULRICH, LAESSLE, REINHOLD G., TUSCHL, REINHARD J., BROOCKS, ANDREAS, KRUSCHE, THOMAS, PIRKE, KARL-MARTIN

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1989

Language:

english

File:

PDF, 526 KB

english, 1989

86

ELAVL1 Modulates Transcriptome-wide miRNA Binding in Murine Macrophages

Lu, Yi-Chien, Chang, Sung-Hee, Hafner, Markus, Li, Xi, Tuschl, Thomas, Elemento, Olivier, Hla, Timothy

Journal:

Year:

2014

Language:

english

File:

PDF, 3.91 MB

english, 2014

87

Specific RNAi Mediated Gene Knockdown in Zebrafish Cell Lines

Gruber, Jens, Manninga, Heiko, Tuschl, Thomas, Osborn, Mary, Weber, Klaus

Journal:

Year:

2005

Language:

english

File:

PDF, 547 KB

english, 2005

88

Hammerhead Ribozymes: Importance of Stem-Loop II for Activity

Thomas Tuschl and Fritz Eckstein

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 735 KB

english, 1993

89

Discovery and Characterization of piRNAs in the Human Fetal Ovary

Williams, Zev, Morozov, Pavel, Mihailovic, Aleksandra, Lin, Carolina, Puvvula, Pavan Kumar, Juranek, Stefan, Rosenwaks, Zev, Tuschl, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 2.71 MB

english, 2015

90

Gene Silencing with siRNA Duplexes Composed of Target-mRNA-Complementary and Partially Palindromic or Partially Complementary Single-Stranded siRNAs

Hossbach, Markus, Gruber, Jens, Osborn, Mary, Weber, Klaus, Tuschl, Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

91

Dieting causes menstrual irregularities in normal weight young women through impairment of episodic luteinizing hormone secretion

Pirke, Karl M., Schweiger, Ulrich, Strowitzki, Thomas, Tuschl, Reinhard J., Laessle, Reinhold G., Broocks, Andreas, Huber, Brigitte, Middendorf, Ralf

Journal:

Fertility and Sterility

Year:

1989

Language:

english

File:

PDF, 846 KB

english, 1989

92

Co-repressor CBFA2T2 regulates pluripotency and germline development

Tu, Shengjiang, Narendra, Varun, Yamaji, Masashi, Vidal, Simon E., Rojas, Luis Alejandro, Wang, Xiaoshi, Kim, Sang Yong, Garcia, Benjamin A., Tuschl, Thomas, Stadtfeld, Matthias, Reinberg, Danny

Journal:

Year:

2016

Language:

english

File:

PDF, 4.81 MB

english, 2016

93

Decreased Follicular Phase Gonadotropin Secretion Is Associated with Impaired Estradiol and Progesterone Secretion during the Follicular and Luteal Phases in Normally Menstruating Women

SCHWEIGER, ULRICH, LAESSLE, REINHOLD G., TUSCHL, REINHARD J., BROOCKS, ANDREAS, KRUSCHE, THOMAS, PIRKE, KARL-MARTIN

Journal:

Obstetric and Gynecologic Survey

Year:

1989

File:

PDF, 144 KB

1989

94

Unique microRNAs appear at different times during the course of a delayed-type hypersensitivity reaction in human skin

Gulati, Nicholas, Løvendorf, Marianne B., Zibert, John R., Akat, Kemal M., Renwick, Neil, Tuschl, Thomas, Krueger, James G.

Journal:

Experimental Dermatology

Year:

2015

Language:

english

File:

PDF, 499 KB

english, 2015

95

[Society of Petroleum Engineers IADC/SPE Drilling Conference and Exhibition - New Orleans, Louisiana, USA (2010-02-02)] IADC/SPE Drilling Conference and Exhibition - Behaviour and Shape of Gas Kicks in Well Bores

Spoerker, Hermann F., Tuschl, Thomas

Language:

english

File:

PDF, 232 KB

english

96

Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS

Teplova, Marianna, Farazi, Thalia A., Tuschl, Thomas, Patel, Dinshaw J.

Journal:

Quarterly Reviews of Biophysics

Year:

2015

Language:

english

File:

PDF, 883 KB

english, 2015

97

MicroRNA Sequence Profiles of Human Kidney Allografts With or Without Tubulointerstitial Fibrosis

Ben-Dov, Iddo Z., Muthukumar, Thangamani, Morozov, Pavel, Mueller, Franco B., Tuschl, Thomas, Suthanthiran, Manikkam

Journal:

Transplantation Journal

Year:

2012

Language:

english

File:

PDF, 558 KB

english, 2012

98

Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF

Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas

Journal:

Year:

2016

Language:

english

File:

PDF, 1.76 MB

english, 2016

99

Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins

Garzia, Aitor, Meyer, Cindy, Morozov, Pavel, Sajek, Marcin, Tuschl, Thomas

Journal:

Year:

2016

Language:

english

File:

PDF, 2.41 MB

english, 2016

100

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

Tuschl, Karin, Meyer, Esther, Valdivia, Leonardo E., Zhao, Ningning, Dadswell, Chris, Abdul-Sada, Alaa, Hung, Christina Y., Simpson, Michael A., Chong, W. K., Jacques, Thomas S., Woltjer, Randy L., Ea

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 3.79 MB

english, 2016

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