Ted R. Hupp: search on Z-Library

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51

Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein

Gray, Terry A., Murray, Euan, Nowicki, Matthew W., Remnant, Lucy, Scherl, Alexander, Muller, Petr, Vojtesek, Borek, Hupp, Ted R.

Journal:

Protein Science

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

52

The Development of a CDK2-Docking Site Peptide that Inhibits p53 and Sensitizes Cells to Death

Ferguson, Michelle, Luciani, M.Gloria, Finlan, Lee, Ibbotson, Sally, Fersht, Alan, Hupp, Ted R.

Journal:

Year:

2004

Language:

english

File:

PDF, 747 KB

english, 2004

53

Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond

Clarke, David J., Murray, Euan, Faktor, Jakub, Mohtar, Aiman, Vojtesek, Borek, MacKay, C. Logan, Smith, Pat Langridge, Hupp, Ted R.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2016

Language:

english

File:

PDF, 2.30 MB

english, 2016

54

DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site

Blaydes, Jeremy P, Hupp, Ted R

Journal:

Year:

1998

File:

PDF, 2.43 MB

1998

55

Hypoxia attenuates the p53 response to cellular damage

Achison, Marcus, Hupp, Ted R

Journal:

Year:

2003

Language:

english

File:

PDF, 352 KB

english, 2003

56

On the Mechanism of Sequence-specific DNA-dependent Acetylation of p53: The Acetylation Motif is Exposed upon DNA Binding

Pavla Češková, Havovi Chichger, Maura Wallace, Borek Vojtesek, Ted R. Hupp

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.13 MB

english, 2006

57

Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2

Gray, Terry A., Alsamman, Khaldoon, Murray, Euan, Sims, Andrew H., R. Hupp, Ted

Journal:

Molecular BioSystems

Year:

2014

Language:

english

File:

PDF, 3.32 MB

english, 2014

58

The human oesophageal squamous epithelium exhibits a novel type of heat shock protein response

Adam Yagui-Beltran, Ashley L. Craig, Laura Lawrie, Devon Thompson, Sarka Pospisilova, David Johnston, Neil Kernohan, David Hopwood, John F. Dillon, Ted R. Hupp

Journal:

Year:

2001

Language:

english

File:

PDF, 804 KB

english, 2001

59

The alternative splice variant of DAPK-1, s-DAPK-1, induces proteasome-independent DAPK-1 destabilization

Yao Lin, Craig Stevens, Ben Harrison, Suresh Pathuri, Eliana Amin, Ted R. Hupp

Journal:

Molecular and Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

60

Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway

Yao Lin, Paul Henderson, Susanne Pettersson, Jack Satsangi, Ted Hupp, Craig Stevens

Journal:

Year:

2011

Language:

english

File:

PDF, 559 KB

english, 2011

61

Chek2ing out the p53 pathway: Can Puma lead the way?

Hollstein, Monica, Hupp, Ted

Journal:

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

62

Novel phosphorylation sites of human tumour suppressor protein p53 at Ser 20 and Thr 18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers

CRAIG, Ashley L., BURCH, Lindsay, VOJTESEK, Borek, MIKUTOWSKA, Jaroslava, THOMPSON, Alastair, HUPP, Ted R.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

63

High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Hughes, Rebecca E., Elliott, Richard J. R., Munro, Alison F., Makda, Ashraff, OâNeill, J. Robert, Hupp, Ted, Carragher, Neil O.

Journal:

Year:

2020

File:

PDF, 3.95 MB

2020

64

Dual-Site Regulation of MDM2 E3-Ubiquitin Ligase Activity

Maura Wallace, Erin Worrall, Susanne Pettersson, Ted R. Hupp, Kathryn L. Ball

Journal:

Year:

2006

Language:

english

File:

PDF, 968 KB

english, 2006

65

A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2

Nicholson, Judith, Scherl, Alex, Way, Luke, A. Blackburn, Elizabeth, D. Walkinshaw, Malcolm, L. Ball, Kathryn, R. Hupp, Ted

Journal:

Cellular Signalling

Year:

2014

Language:

english

File:

PDF, 2.15 MB

english, 2014

66

Evidence for allosteric effects on p53 oligomerization induced by phosphorylation

Muller, Petr, Chan, Juliana M., Simoncik, Oliver, Fojta, Miroslav, Lane, David P., Hupp, Ted, Vojtesek, Borivoj

Journal:

Protein Science

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

67

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor

Yuan, Meng, McNae, Iain W., Chen, Yiyuan, Blackburn, Elizabeth A., Wear, Martin A., Michels, Paul A.M., Fothergill-Gilmore, Linda A., Hupp, Ted, Walkinshaw, Malcolm D.

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 4.91 MB

english, 2018

68

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis

Herranz, Maria Gómez, Nekulova, Marta, Faktor, Jakub, Hernychova, Lenka, Kote, Sachin, Sinclair, Elizabeth H., Nenutil, Rudolf, Vojtesek, Borivoj, Ball, Kathryn L., Hupp, Ted R.

Journal:

Cellular Signalling

Year:

2019

File:

PDF, 17.32 MB

2019

69

The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276

Li, Ruidong, Zatloukalova, Pavlina, Muller, Petr, Gil-Mir, Maria, Kote, Sachin, Wilkinson, Simon, Kemp, Alain J., Hernychova, Lenka, Wang, Yaxin, Ball, Kathryn L., Tao, Kaixiong, Hupp, Ted, Vojtesek,

Journal:

Cellular & Molecular Biology Letters

Year:

2020

File:

PDF, 2.73 MB

2020

70

An animal model to evaluate the function and regulation of the adaptively evolving stress protein SEP53 in oesophageal bile damage responses

Lenny Nelson, Susan Anderson, Alan L. Archibald, Susan Rhind, Zen H. Lu, Alison Condie, Neal McIntyre, Jill Thompson, Rudolf Nenutil, Borek Vojtesek, C. Bruce A. Whitelaw, Tom J. Little, Ted Hupp

Journal:

Cell Stress and Chaperones

Year:

2008

Language:

english

File:

PDF, 791 KB

english, 2008

71

Expansion of Protein Interaction Maps by Phage Peptide Display Using MDM2 as a Prototypical Conformationally Flexible Target Protein

Lindsay Burch, Harumi Shimizu, Amanda Smith, Cam Patterson, Ted R. Hupp

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.43 MB

english, 2004

72

Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2

POSPÍŠILOVÁ, Šárka, BRÁZDA, Václav, KUCHAŘÍKOVÁ, Kateřina, LUCIANI, M. Gloria, HUPP, Ted R., SKLÁDAL, Petr, PALEČEK, Emil, VOJTĚŠEK, Bořivoj

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 229 KB

english, 2004

73

Quantitative shotgun proteomics unveils candidate novel oesophageal adenocarcinoma-specific proteins

O'Neill, J. Robert, Pak, Hui-Song, Pairo-Castineira, Erola, Save, Vicki, Paterson-Brown, Simon, Nenutil, Rudolf, Vojtěšek, Bořivoj, Overton, Ian, Scherl, Alex, Hupp, Ted R.

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 4.12 MB

english, 2017

74

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1

Craig Stevens, Susanne Pettersson, Bartosz Wawrzynow, Maura Wallace, Kathryn Ball, Alicja Zylicz, Ted R. Hupp

Journal:

Year:

2008

Language:

english

File:

PDF, 400 KB

english, 2008

75

Allosteric activation of latent p53 tetramers

Ted R. Hupp, David P. Lane

Journal:

Current Biology

Year:

1994

Language:

english

File:

PDF, 1.30 MB

english, 1994

76

Redox regulation of tumour suppressor protein p53: identification of the sites of hydrogen peroxide oxidation and glutathionylation

Scotcher, Jenna, Clarke, David J., Mackay, C. Logan, Hupp, Ted, Sadler, Peter J., Langridge-Smith, Pat R. R.

Journal:

Chemical Science

Year:

2013

Language:

english

File:

PDF, 2.38 MB

english, 2013

77

Death from Inside Out: The Role of Apoptosis in Development, Tissue Homeostasis and Malignancy || The Role of the p53 Protein in the Apoptotic Response

D. P. Lane, Xin Lu, Ted Hupp and P. A. Hall

Journal:

Philosophical Transactions Biological Sciences

Year:

1994

Language:

english

File:

PDF, 572 KB

english, 1994

78

Activation of the cryptic DNA binding function of mutant forms of p53

Hupp, Ted R., Meek, David W., Midgley, Carol A., Lane, David P.

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 8.80 MB

english, 1993

79

Regulation of transcriptional activators by DNA-binding domain ubiquitination

Landré, Vivien, Revi, Bhindu, Mir, Maria Gil, Verma, Chandra, Hupp, Ted R, Gilbert, Nick, Ball, Kathryn L

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 4.66 MB

english, 2017

80

Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif

Erin G. Worrall, Bartosz Wawrzynow, Liam Worrall, Malcolm Walkinshaw, Kathryn L. Ball, Ted R. Hupp

Journal:

Journal of Chemical Biology

Year:

2009

Language:

english

File:

PDF, 772 KB

english, 2009

81

Identification of Two Reactive Cysteine Residues in the Tumor Suppressor Protein p53 Using Top-Down FTICR Mass Spectrometry

Jenna Scotcher, David J. Clarke, Stefan K. Weidt, C. Logan Mackay, Ted R. Hupp, Peter J. Sadler, Pat R. R. Langridge-Smith

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 734 KB

english, 2011

82

The regulation of CHK2 in human cancer

Craig, Ashley L, Hupp, Ted R

Journal:

Year:

2004

Language:

english

File:

PDF, 191 KB

english, 2004

83

Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers

CRAIG, Ashley L., BURCH, Lindsay, VOJTESEK, Borek, MIKUTOWSKA, Jaroslava, THOMPSON, Alastair, HUPP, Ted R.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

84

Screening and Identification of PLK1-Polo Box Binding Peptides by High-Throughput Sequencing of Phage-Selected Libraries

Bibi, Nousheen, Niaz, Hafsa, Hupp, Ted, Kamal, Mohammad Amjad, Rashid, Sajid

Journal:

Protein & Peptide Letters

Year:

2019

Language:

english

File:

PDF, 12.46 MB

english, 2019

85

Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometry

Hernychova, Lenka, Man, Petr, Verma, Chandra, Nicholson, Jude, Sharma, Carrie-Anne, Ruckova, Eva, Teo, Jin Yuan, Ball, Kathryn, Vojtesek, Borek, Hupp, Ted R.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

86

Phosphomimetic Mutation of the N-Terminal Lid of MDM2 Enhances the Polyubiquitination of p53 through Stimulation of E2-Ubiquitin Thioester Hydrolysis

Fraser, Jennifer A., Worrall, Erin G., Lin, Yao, Landre, Vivien, Pettersson, Susanne, Blackburn, Elizabeth, Walkinshaw, Malcolm, Muller, Petr, Vojtesek, Borek, Ball, Kathryn, Hupp, Ted R.

Journal:

Journal of Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

87

Global Gene Expression Analysis of Canine Osteosarcoma Stem Cells Reveals a Novel Role for COX-2 in Tumour Initiation

Pang, Lisa Y., Gatenby, Emma L., Kamida, Ayako, Whitelaw, Bruce A., Hupp, Ted R., Argyle, David J., Thamm, Douglas

Journal:

Year:

2014

Language:

english

File:

PDF, 2.80 MB

english, 2014

88

Death-associated protein kinase (DAPK) and signal transduction

Journal:

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

89

Evaluating DAPK as a therapeutic target

Huang, Yide, Chen, Ling, Guo, Libin, Hupp, Ted R., Lin, Yao

Journal:

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

90

Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity

Fraser, Jennifer A., Hupp, Ted R.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.26 MB

english, 2007

91

Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo

Shimizu, Harumi, Saliba, David, Wallace, Maura, Finlan, Lee, Langridge-Smith, Patrick R. R., Hupp, Ted R.

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 703 KB

english, 2006

92

Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death

Yao Lin, Ted R. Hupp, Craig Stevens

Journal:

Year:

2010

Language:

english

File:

PDF, 202 KB

english, 2010

93

The regulation of MDM2 by multisite phosphorylation—Opportunities for molecular-based intervention to target tumours?

David W. Meek, Ted R. Hupp

Journal:

Seminars in Cancer Biology

Year:

2010

Language:

english

File:

PDF, 672 KB

english, 2010

94

The Effects of Phosphomimetic Lid Mutation on the Thermostability of the N-terminal Domain of MDM2

Erin G. Worrall, Liam Worrall, Elizabeth Blackburn, Malcolm Walkinshaw, Ted R. Hupp

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.98 MB

english, 2010

95

Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization

Kofod-Olsen, Emil, Pettersson, Susanne, Wallace, Maura, Abduljabar, Ahmed Basim, Øster, Bodil, Hupp, Ted, Höllsberg, Per

Journal:

Year:

2014

Language:

english

File:

PDF, 3.52 MB

english, 2014

96

Protein kinases coordinately regulate the p53:ΔNp63α axis after DNA damage

Pang, Lisa Y., Hupp, Ted R.

Journal:

Year:

2008

Language:

english

File:

PDF, 313 KB

english, 2008

97

The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway

Maclaine, Nicola J., Hupp, Ted R.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.21 MB

english, 2009

98

Copy number variation: a prognostic marker for young patients with squamous cell carcinoma of the oral tongue

Gu, Xiaolian, Coates, Philip J, Boldrup, Linda, Wang, Lixiao, Krejci, Adam, Hupp, Ted, Fahraeus, Robin, Norberg-Spaak, Lena, Sgaramella, Nicola, Wilms, Torben, Nylander, Karin

Journal:

Journal of Oral Pathology & Medicine

Year:

2018

Language:

english

File:

PDF, 657 KB

english, 2018

99

Discovering Putative Protein Targets of Small Molecules: A Study of the p53 Activator Nutlin

Nguyen, Minh N., Sen, Neeladri, Lin, Mei Yin, Joseph, Thomas L, Vaz, Candida, Tanavde, Vivek, Way, Luke, Hupp, Ted R., Verma, Chandra S., MADHUSUDHAN, Mallur Srivatsan

Journal:

Journal of Chemical Information and Modeling

Year:

2019

File:

PDF, 1.07 MB

2019

100

Discovering Putative Protein Targets of Small Molecules: A Study of the p53 Activator Nutlin

Nguyen, Minh N., Sen, Neeladri, Lin, Mei Yin, Joseph, Thomas L, Vaz, Candida, Tanavde, Vivek, Way, Luke, Hupp, Ted R., Verma, Chandra S., MADHUSUDHAN, Mallur Srivatsan

Journal:

Journal of Chemical Information and Modeling

Year:

2019

Language:

english

File:

PDF, 1.07 MB

english, 2019

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