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1

Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals

Alicia Felip, Silvia Zanuy, Rafael Pineda, Leonor Pinilla, Manuel Carrillo, Manuel Tena-Sempere, Ana Gómez

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.93 MB

english, 2009

2

Molecular mechanisms of leptin action in adult rat testis: potential targets for leptin-induced inhibition of steroidogenesis and pattern of leptin receptor messenger ribonucleic acid expression

Tena-Sempere, M

Journal:

Journal of Endocrinology

Year:

2001

Language:

english

File:

PDF, 229 KB

english, 2001

3

Neuropeptide Control of Puberty: Beyond Kisspeptins

Barroso, Alexia, Roa, Juan, Tena-Sempere, Manuel

Journal:

Seminars in Reproductive Medicine

Year:

2019

Language:

english

File:

PDF, 262 KB

english, 2019

4

Effects of chronic food restriction and treatments with leptin or ghrelin on different reproductive parameters of male rats

Alexander V. Sirotkin, Maria Chrenková, Soňa Nitrayová, Peter Patraš, Krzysztof Darlak, Francisco Valenzuela, Leonor Pinilla, Manuel Tena-Sempere

Journal:

Year:

2008

Language:

english

File:

PDF, 575 KB

english, 2008

5

Leptin in male reproduction: the testis paradigm

M. Tena-Sempere, M.L. Barreiro

Journal:

Molecular and Cellular Endocrinology

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

6

Roles of Ghrelin and Leptin in the Control of Reproductive Function

Tena-Sempere, Manuel

Journal:

Neuroendocrinology

Year:

2007

Language:

english

File:

PDF, 369 KB

english, 2007

7

Metabolic control of puberty: Roles of leptin and kisspeptins

Sanchez-Garrido, Miguel A., Tena-Sempere, Manuel

Journal:

Hormones and Behavior

Year:

2013

Language:

english

File:

PDF, 539 KB

english, 2013

8

Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: Kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism

George, Jyothis T., Veldhuis, Johannes D., Tena-Sempere, Manuel, Millar, Robert P., Anderson, Richard A.

Journal:

Clinical Endocrinology

Year:

2013

Language:

english

File:

PDF, 197 KB

english, 2013

9

Knobil and Neill's Physiology of Reproduction || Physiological Mechanisms for the Metabolic Control of Reproduction

Tena-Sempere, Manuel

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

10

GPR54 and kisspeptin in reproduction

Tena-Sempere, M.

Journal:

Human Reproduction Update

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

11

The Integrated Hypothalamic Tachykinin-Kisspeptin System as a Central Coordinator for Reproduction

Navarro, Víctor M., Bosch, Martha A., León, Silvia, Simavli, Serap, True, Cadence, Pinilla, Leonor, Carroll, Rona S., Seminara, Stephanie B., Tena-Sempere, Manuel, Rønnekleiv, Oline K., Kaiser, Ursula

Journal:

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

12

Female reproduction and type 1 diabetes: from mechanisms to clinical findings

Codner, E., Merino, P. M., Tena-Sempere, M.

Journal:

Human Reproduction Update

Year:

2012

Language:

english

File:

PDF, 604 KB

english, 2012

13

Hypothalamic AMPK: a canonical regulator of whole-body energy balance

López, Miguel, Nogueiras, Rubén, Tena-Sempere, Manuel, Diéguez, Carlos

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2016

Language:

english

File:

PDF, 531 KB

english, 2016

14

The roles of kisspeptins and G protein-coupled receptor-54 in pubertal development

Tena-Sempere, Manuel

Journal:

Current Opinion in Pediatrics

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

15

Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease

Jokela, Heli, Hakkarainen, Janne, Kätkänaho, Laura, Pakarinen, Pirjo, Ruohonen, Suvi T., Tena-Sempere, Manuel, Zhang, Fu-Ping, Poutanen, Matti

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 10.32 MB

english, 2017

16

Unique Features of a Unique Cell: The Wonder World of GnRH Neurons

Roa, Juan, Tena-Sempere, Manuel

Journal:

Year:

2018

Language:

english

File:

PDF, 82 KB

english, 2018

17

Role of kisspeptins in the control of the hypothalamic-pituitary-ovarian axis: old dogmas and new challenges

Ruohonen, Suvi T., Poutanen, Matti, Tena-Sempere, Manuel

Journal:

Fertility and Sterility

Year:

2020

File:

PDF, 309 KB

2020

18

Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system

Esteban Lavaque, Aurora Mayen, Iñigo Azcoitia, Manuel Tena-Sempere, Luis M. Garcia-Segura

Journal:

Developmental Neurobiology

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

19

Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism

Luis Varela, Noelia Martínez-Sánchez, Rosalía Gallego, María J Vázquez, Juan Roa, Marina Gándara, Erik Schoenmakers, Rubén Nogueiras, Krishna Chatterjee, Manuel Tena-Sempere, Carlos Diéguez, Miguel Ló

Journal:

The Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 4.36 MB

english, 2012

20

Interactions between serotoninergic and aminoacidergic pathways in the control of PRL secretion in prepubertal male rats

L. Pinilla, L. C. González, M. Tena-Sempere, E. Aguilar

Journal:

Journal of Physiology and Biochemistry

Year:

2001

Language:

english

File:

PDF, 1.17 MB

english, 2001

21

Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation?

María Gaytán, Juan M. Castellano, Juan Roa, José E. Sánchez-Criado, Manuel Tena-Sempere, Francisco Gaytán

Journal:

Cell and Tissue Research

Year:

2007

Language:

english

File:

PDF, 528 KB

english, 2007

22

Regulation of Growth Hormone (GH) secretion by different glutamate receptor subtypes in the rat

M. Tena-Sempere, L. Pinilla, L. C. González, E. Aguilar

Journal:

Year:

2000

Language:

english

File:

PDF, 210 KB

english, 2000

23

Neuroendocrine factors in the initiation of puberty: The emergent role of kisspeptin

Victor M. Navarro, Juan M. Castellano, David García-Galiano, Manuel Tena-Sempere

Journal:

Reviews in Endocrine & Metabolic Disorders

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

24

Hypothalamic AMP-activated protein kinase as a mediator of whole body energy balance

Pablo Blanco Martínez de Morentin, Carmen R. González, Asisk K. Saha, Luís Martins, Carlos Diéguez, Antonio Vidal-Puig, Manuel Tena-Sempere, Miguel López

Journal:

Reviews in Endocrine & Metabolic Disorders

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

25

The KiSS-1/GPR54 system: putative target for endocrine disruption of reproduction at hypothalamic–pituitary unit?

Victor M. Navarro, Manuel Tena-Sempere

Journal:

International Journal of Andrology

Year:

2008

Language:

english

File:

PDF, 93 KB

english, 2008

26

Kisspeptin/GPR54 system as potential target for endocrine disruption of reproductive development and function

M. Tena-Sempere

Journal:

International Journal of Andrology

Year:

2010

Language:

english

File:

PDF, 107 KB

english, 2010

27

Characterization of the kisspeptin system in human spermatozoa

F. M. Pinto, A. Cejudo-Román, C. G. Ravina, M. Fernández-Sánchez, D. Martín-Lozano, M. Illanes, M. Tena-Sempere, M. L. Candenas

Journal:

International Journal of Andrology

Year:

2012

Language:

english

File:

PDF, 493 KB

english, 2012

28

Regulation of Peroxisome Proliferator Activated Receptor-γ in Rat Pituitary

R. Nogueiras, J. E. Caminos, R. Gallego, K. Raghay, S. Bravo, S. Tovar, C. Pombo, M. López, M. Tena-Sempere, T. García-Caballero, C. Diéguez

Journal:

Journal of Neuroendocrinology

Year:

2005

Language:

english

File:

PDF, 242 KB

english, 2005

29

Differential Contribution of Nitric Oxide and cGMP to the Stimulatory Effects of Growth Hormone-Releasing Hormone and Low-Concentration Somatostatin on Growth Hormone Release from Somatotrophs

R. M. Luque, F. Rodríguez-Pacheco, M. Tena-Sempere, F. Gracia-Navarro, M. M. Malagón, J. P. Castaño

Journal:

Journal of Neuroendocrinology

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

30

Hypothalamic Expression of Human Growth Hormone Induces Post-Pubertal Hypergonadotrophism in Male Transgenic Growth Retarded Rats

J. S. Davies, N. M. Thompson, H. C. Christian, L. Pinilla, F. J. P. Ebling, M. Tena-Sempere, T. Wells

Journal:

Journal of Neuroendocrinology

Year:

2006

Language:

english

File:

PDF, 919 KB

english, 2006

31

Direct Pituitary Effects of Kisspeptin: Activation of Gonadotrophs and Somatotrophs and Stimulation of Luteinising Hormone and Growth Hormone Secretion

E. Gutiérrez-Pascual, A. J. Martínez-Fuentes, L. Pinilla, M. Tena-Sempere, M. M. Malagón, J. P. Castaño

Journal:

Journal of Neuroendocrinology

Year:

2007

Language:

english

File:

PDF, 697 KB

english, 2007

32

Ghrelin Induces Growth Hormone Secretion Via a Nitric Oxide /cGMP Signalling Pathway

F. Rodríguez-Pacheco, R. M. Luque, M. Tena-Sempere, M. M. Malagón, J. P. Castaño

Journal:

Journal of Neuroendocrinology

Year:

2008

Language:

english

File:

PDF, 127 KB

english, 2008

33

Activation of Microglia in Specific Hypothalamic Nuclei and the Cerebellum of Adult Rats Exposed to Neonatal Overnutrition

S. Tapia-González, Lhav M. García-Segura, M. Tena-Sempere, L. M. Frago, J. M. Castellano, E. Fuente-Martín, C. García-Cáceres, J. Argente, J. A. Chowen

Journal:

Journal of Neuroendocrinology

Year:

2011

Language:

english

File:

PDF, 194 KB

english, 2011

34

Sex Steroids and the Control of the Kiss1 System: Developmental Roles and Major Regulatory Actions

D. García-Galiano, L. Pinilla, M. Tena-Sempere

Journal:

Journal of Neuroendocrinology

Year:

2012

Language:

english

File:

PDF, 212 KB

english, 2012

35

Orexins (hypocretins) actions on the GHRH/somatostatin-GH axis

M. López, R. Nogueiras, M. Tena-Sempere, C. Diéguez

Journal:

Acta Physiologica

Year:

2010

Language:

english

File:

PDF, 275 KB

english, 2010

36

Orexins and the regulation of the hypothalamic-pituitary-testicular axis

M. Nurmio, M. Tena-Sempere, J. Toppari

Journal:

Acta Physiologica

Year:

2010

Language:

english

File:

PDF, 192 KB

english, 2010

37

Timeline: the role of kisspeptins in reproductive biology

Tena-Sempere, Manuel

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

38

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54

V. M. Navarro, R. Fernández-Fernández, J. M. Castellano, J. Roa, A. Mayen, M. L. Barreiro, F. Gaytan, E. Aguilar, L. Pinilla, C. Dieguez, M. Tena-Sempere

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

39

Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis

V. M. Navarro, R. Fernández-Fernández, R. Nogueiras, E. Vigo, S. Tovar, N. Chartrel, O. Le Marec, J. Leprince, E. Aguilar, L. Pinilla, C. Dieguez, H. Vaudry, M. Tena-Sempere

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 660 KB

english, 2006

40

Role of excitatory amino acids in the control of growth hormone secretion

Enrique Aguilar, Manuel Tena-Sempere, Leonor Pinilla

Journal:

Endocrine (Springer)

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

41

Structure and expression of the rat relaxin-like factor (RLF) gene

Andrej-Nikolai Spiess, Marga Balvers, Manuel Tena-Sempere, Ilpo Huhtaniemi, Laura Parry, Richard Ivell

Journal:

Molecular Reproduction and Development

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

42

Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility

Navarro, Victor M., Tena-Sempere, Manuel

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2011

Language:

english

File:

PDF, 1.34 MB

english, 2011

43

Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms

Pinilla, L., Aguilar, E., Dieguez, C., Millar, R. P., Tena-Sempere, M.

Journal:

Physiological Reviews

Year:

2012

Language:

english

File:

PDF, 2.29 MB

english, 2012

44

Kisspeptins: Bridging energy homeostasis and reproduction

Juan M. Castellano, Agnete H. Bentsen, Jens D. Mikkelsen, Manuel Tena-Sempere

Journal:

Year:

2010

Language:

english

File:

PDF, 386 KB

english, 2010

45

Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats

Esther Fuente-Martín, Miriam Granado, Cristina García-Cáceres, Miguel A. Sanchez-Garrido, Laura M. Frago, Manuel Tena-Sempere, Jesús Argente, Julie A. Chowen

Journal:

Year:

2012

Language:

english

File:

PDF, 803 KB

english, 2012

46

Structure–activity evaluation of kisspeptin-10-related peptides

L. Guilhaudis, E. Desperrois, A. Lebreton, J. Leprince, E. Gutiérrez-Pascual, A.J. Martínez-Fuentes, R. Pineda, J. Roa, M. Duran-Prado, L. Pinilla, M.M. Malagón, M. Tena-Sempere, J.P. Castaño, M.C. To

Journal:

Regulatory Peptides

Year:

2010

Language:

english

File:

PDF, 59 KB

english, 2010

47

Regulation of pituitary cell function by the adipokine adiponectin

M.M. Malagón, F. Rodríguez-Pacheco, A.J. Martínez-Fuentes, S. Tovar, L. Pinilla, M. Tena-Sempere, C. Diéguez, J.P. Castaño

Journal:

Frontiers in Neuroendocrinology

Year:

2006

Language:

english

File:

PDF, 40 KB

english, 2006

48

The localisation of kisspeptin in the rodent brain

Jens D. Mikkelsen, Florent Revel, Manuel Tena-Sempere, Leif K. Larsen, Henrik H. Hansen, Mireille Masson-Pévét, Paul Pévét, Valerie Simonneaux

Journal:

Frontiers in Neuroendocrinology

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

49

Sexual differentiation of Kiss1 expression in the brain of the rat

M. Tena-Sempere, A.S. Kauffman, J. Roa, V.M. Navarro, M.L. Gottsch, D.K. Clifton, R.A. Steiner

Journal:

Frontiers in Neuroendocrinology

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

50

New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function

Juan Roa, Enrique Aguilar, Carlos Dieguez, Leonor Pinilla, Manuel Tena-Sempere

Journal:

Frontiers in Neuroendocrinology

Year:

2008

Language:

english

File:

PDF, 374 KB

english, 2008