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51

Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival

Tinkum, Kelsey L., Stemler, Kristina M., White, Lynn S., Loza, Andrew J., Jeter-Jones, Sabrina, Michalski, Basia M., Kuzmicki, Catherine, Pless, Robert, Stappenbeck, Thaddeus S., Piwnica-Worms, David,

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 2.12 MB

english, 2015

52

Crohn disease: A current perspective on genetics, autophagy and immunity

Stappenbeck, Thaddeus S., Rioux, John D., Mizoguchi, Atsushi, Saitoh, Tatsuya, Huett, Alan, Darfeuille-Michaud, Arlette, Wileman, Tom, Mizushima, Noboru, Carding, Simon, Parkes, Miles, Xavier, Ramnik

Journal:

Year:

2011

Language:

english

File:

PDF, 3.90 MB

english, 2011

53

P-070 An Integrated Risk Stratification System Incorporating Paneth Cell Phenotype and Clinical Parameter Predicts Outcome in Post-operative Crohn’s Disease Patients

Ta-Chiang, Liu, Feng, Gao, Thaddeus, Stappenbeck

Journal:

Inflammatory Bowel Diseases

Year:

2014

Language:

english

File:

PDF, 743 KB

english, 2014

54

O-013 Defining the Basis of Epithelial Defects in Crohnʼs Using Intestinal Spheroid Culture

VanDussen, Kelli, Miyoshi, Hiroyuki, Sonnek, Naomi, Ciorba, Matthew, Stappenbeck, Thaddeus

Journal:

Inflammatory Bowel Diseases

Year:

2016

Language:

english

File:

PDF, 79 KB

english, 2016

55

P-122 Bacteroides Thetaiotaomicron Induce Tregs in the Colon in a Capsule Independent Mechanism

Wegorzewska, Marta, Donermeyer, David, Martens, Eric, Stappenbeck, Thaddeus, Allen, Paul

Journal:

Inflammatory Bowel Diseases

Year:

2016

File:

PDF, 70 KB

2016

56

P-122 Bacteroides Thetaiotaomicron Induce Tregs in the Colon in a Capsule Independent Mechanism

Wegorzewska, Marta, Donermeyer, David, Martens, Eric, Stappenbeck, Thaddeus, Allen, Paul

Journal:

Inflammatory Bowel Diseases

Year:

2016

Language:

english

File:

PDF, 70 KB

english, 2016

57

A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease

Cadwell, Ken, Patel, Khushbu K., Komatsu, Masaaki, Virgin, IV, Herbert W., Stappenbeck, Thaddeus S.

Journal:

Year:

2009

Language:

english

File:

PDF, 489 KB

english, 2009

58

Challenges in IBD Research

Denson, Lee A., Long, Millie D., McGovern, Dermot P. B., Kugathasan, Subra, Wu, Gary D., Young, Vincent B., Pizarro, Theresa T., de Zoeten, Edwin F., Stappenbeck, Thaddeus S., Plevy, Scott E., Abraham

Journal:

Inflammatory Bowel Diseases

Year:

2013

Language:

english

File:

PDF, 106 KB

english, 2013

59

321 Paneth Cell Phenotype is Associated With Novel Genetic Determinants and Clinical Outcome in Japanese Crohn's Disease Patients

Naito, Takeo, Liu, Ta-Chiang, Kakuta, Yoichi, Head, Richard, Liu, Zhenqiu, Haritunians, Talin, Li, Dalin, Endo, Katsuya, Kinouchi, Yoshitaka, McGovern, Dermot, Stappenbeck, Thaddeus, Shimosegawa, Toor

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 497 KB

english, 2016

60

[Methods in Enzymology] Laser Capture Microscopy Volume 356 || [15] Laser capture microdissection of mouse intestine: Characterizing mrna and protein expression, and profiling intermediary metabolism in specified cell populations

Stappenbeck, Thaddeus S

Year:

2002

Language:

english

File:

PDF, 17.53 MB

english, 2002

61

Sa1823 Vitamin D Receptor Affects Small Intestinal Paneth Cell Phenotype in Crohn's Disease Patients Independent of ATG16L1 Modulation

Liu, Ta-Chiang, VanDussen, Kelli L., Stappenbeck, Thaddeus

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 304 KB

english, 2016

62

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

Kaiko, Gerard E., Ryu, Stacy H., Koues, Olivia I., Collins, Patrick L., Solnica-Krezel, Lilianna, Pearce, Edward J., Pearce, Erika L., Oltz, Eugene M., Stappenbeck, Thaddeus S.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

63

Su1873 Identification of IBD-Related Microbial Metabolites Affecting Human Th17 Differentiation

Chang, Yu-Ling, Harre, Nicholas, Rossetti, Maura, Subramanian, Ayshwarya, Kostic, Aleksandar, Huttenhower, Curtis, Xavier, Ramnik, Stappenbeck, Thaddeus, Simpson, Kenneth W., Sartor, R. Balfour, Wu, G

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 537 KB

english, 2016

64

Accounting for reciprocal host–microbiome interactions in experimental science

Stappenbeck, Thaddeus S., Virgin, Herbert W.

Journal:

Year:

2016

Language:

english

File:

PDF, 716 KB

english, 2016

65

Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease

Sun, Lulu, Nava, Gerardo M, Stappenbeck, Thaddeus S

Journal:

Current Opinion in Gastroenterology

Year:

2011

Language:

english

File:

PDF, 153 KB

english, 2011

66

Deciphering the ???black box??? of the intestinal stem cell niche: taking direction from other systems

Walker, Monica R, Stappenbeck, Thaddeus S

Journal:

Current Opinion in Gastroenterology

Year:

2008

Language:

english

File:

PDF, 114 KB

english, 2008

67

Tracking Cell Lineage to Rediscover (again) the Switch from Ciliated to Mucous Cells

Patel, Anand C., Brody, Steven L., Stappenbeck, Thaddeus S., Holtzman, Michael J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

68

Mesenchymal stem cell therapy of intestinal disease: are their effects systemic or localized?

Manieri, Nicholas A, Stappenbeck, Thaddeus S

Journal:

Current Opinion in Gastroenterology

Year:

2011

Language:

english

File:

PDF, 195 KB

english, 2011

69

Structure of Desmoplakin and Its Association with Intermediate Filaments

Green, Kathleen J., Stappenbeck, Thaddeus S., Parry, David A.D., Virata, M. Luisa A.

Journal:

The Journal of Dermatology

Year:

1992

Language:

english

File:

PDF, 503 KB

english, 1992

70

Cellular differentiation: potential insight into butyrate paradox?

Ryu, Stacy H., Kaiko, Gerard E., Stappenbeck, Thaddeus S.

Journal:

Molecular & Cellular Oncology

Year:

2016

Language:

english

File:

PDF, 1.84 MB

english, 2016

71

Paneth Cell Alterations in the Development and Phenotype of Crohn’s Disease

Stappenbeck, Thaddeus S., McGovern, Dermot P.B.

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 590 KB

english, 2016

72

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

Miyoshi, Hiroyuki, VanDussen, Kelli L, Malvin, Nicole P, Ryu, Stacy H, Wang, Yi, Sonnek, Naomi M, Lai, Chin‐Wen, Stappenbeck, Thaddeus S

Journal:

The EMBO Journal

Year:

2017

Language:

english

File:

PDF, 9.61 MB

english, 2017

73

RNA-SEQ of Formalin-Fixed, Paraffin-Embedded Intestinal Tissue Identifies an Epithelial Defect in crohn's

VanDussen, Kelli L., Liu, Ta-Chiang, Head, Richard, Stappenbeck, Thaddeus S.

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 422 KB

english, 2017

74

Cigarette Smoking Triggers Paneth Cell Defect in Crohn's Disease Patients and Mice Harboring Susceptibility Allele ATG16L1 T300A

Liu, Ta-Chiang, Kern, Justin, Caruso, Roberta, Gao, Feng, McGovern, Dermot, Nunez, Gabriel, Stappenbeck, Thaddeus S.

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 439 KB

english, 2017

75

660

Steed, Ashley, Sun, Lulu, David, Morales, Esaulova, Ekaterina, Artyomov, Maxim, Lenschow, Deborah, Stappenbeck, Thaddeus

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 402 KB

english, 2016

76

ELMO1 regulates the induction of autophagy and bacterial clearance during enteric infection

Sarkar, Arup, Tindle, Courtney, Pranadinata, Rama F, Reed, Sharon, Eckmann, Lars, Stappenbeck, Thaddeus S, Ernst, Peter B, Das, Soumita

Journal:

The Journal of Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 984 KB

english, 2017

77

Assigning function to symbionts

Stappenbeck, Thaddeus S.

Journal:

Nature Microbiology

Year:

2018

Language:

english

File:

PDF, 948 KB

english, 2018

78

Establishing A Mouse Model of Checkpoint Inhibitor-Induced Colitis: Pilot Experiments and Future Directions

Heul, Aaron Ver, Stappenbeck, Thaddeus

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 125 KB

english, 2018

79

A common mechanism links activities of butyrate in the colon

Verma, Mohit S., Fink, Michael J., Salmon, Gabriel L., Fornelos, Nadine, Ohara, Takahiro E., Ryu, Stacy H., Vlamakis, Hera, Xavier, Ramnik J., Stappenbeck, Thaddeus S., Whitesides, George M.

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

80

P063 INTERACTIONS OF GENETIC AND ENVIRONMENTAL FACTORS TRIGGER UNIQUE PPAR-GAMMA SIGNATURE IN PANETH CELLS IN CROHN’S DISEASE SUBJECTS AND RELEVANT MOUSE MODELS

Liu, Ta-Chiang, Kern, Justin, VanDussen, Kelli L., Xiong, Shanshan, Caruso, Roberta, Nunez, Gabriel, Head, Richard, Stappenbeck, Thaddeus S.

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 130 KB

english, 2018

81

Intestinal Stem Cells Live Off the Fat of the Land

Barisas, Derek A.G., Stappenbeck, Thaddeus S.

Journal:

Year:

2018

Language:

english

File:

PDF, 219 KB

english, 2018

82

Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression In Vitro

Wilke, Georgia, Ravindran, Soumya, Funkhouser-Jones, Lisa, Barks, Jennifer, Wang, Qiuling, VanDussen, Kelli L., Stappenbeck, Thaddeus S., Kuhlenschmidt, Theresa B., Kuhlenschmidt, Mark S., Sibley, L.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.72 MB

english, 2018

83

Contributions Made by CDC25 Phosphatases to Proliferation of Intestinal Epithelial Stem and Progenitor Cells

Lee, Gwanghee, Origanti, Sofia, White, Lynn S., Sun, Jinwu, Stappenbeck, Thaddeus S., Piwnica-Worms, Helen, Ling, Ming Tat

Journal:

Year:

2011

Language:

english

File:

PDF, 9.95 MB

english, 2011

84

A Novel Strategy to Increase the Proliferative Potential of Adult Human β-Cells While Maintaining Their Differentiated Phenotype

Aly, Haytham, Rohatgi, Nidhi, Marshall, Connie A., Grossenheider, Tiffani C., Miyoshi, Hiroyuki, Stappenbeck, Thaddeus S., Matkovich, Scot J., McDaniel, Michael L., Liu, Chunming

Journal:

Year:

2013

Language:

english

File:

PDF, 2.53 MB

english, 2013

85

IL-6 Stimulates Intestinal Epithelial Proliferation and Repair after Injury

Kuhn, Kristine A., Manieri, Nicholas A., Liu, Ta-Chiang, Stappenbeck, Thaddeus S., Karhausen, Jörn

Journal:

Year:

2014

Language:

english

File:

PDF, 8.82 MB

english, 2014

86

Tu1258 - Development of Patient-Derived “Small Intestine-On-A-Chip” Microfluidic Devices

Seiler, Kristen, Binkley, Michael, Alvarado, David M., Iticovici, Micah, Goo, William, VanDussen, Kelli L., Stappenbeck, Thaddeus, Rubin, Deborah C., George, Steven, Ciorba, Matthew A., Meacham, Mark,

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 296 KB

english, 2018

87

Su2030 - Farnesoid X Receptor Mediates Western Diet-Induced Paneth Cell Defects

Liu, Ta-Chiang, Kern, Justin, VanDussen, Kelli L., Xiong, Shanshan, Head, Richard, Stappenbeck, Thaddeus

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 409 KB

english, 2018

88

Deep Learning Global Glomerulosclerosis in Transplant Kidney Frozen Sections

Marsh, Jon N., Matlock, Matthew K., Kudose, Satoru, Liu, Ta-Chiang, Stappenbeck, Thaddeus S., Gaut, Joseph P., Swamidass, S. Joshua

Journal:

IEEE Transactions on Medical Imaging

Year:

2018

Language:

english

File:

PDF, 9.00 MB

english, 2018

89

Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses

White, James P., Xiong, Shanshan, Malvin, Nicole P., Khoury-Hanold, William, Heuckeroth, Robert O., Stappenbeck, Thaddeus S., Diamond, Michael S.

Journal:

Year:

2018

Language:

english

File:

PDF, 8.58 MB

english, 2018

90

Microbiome control of innate reactivity

Chen, Feidi, Stappenbeck, Thaddeus S

Journal:

Current Opinion in Immunology

Year:

2019

File:

PDF, 704 KB

2019

91

Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen

Wegorzewska, Marta M., Glowacki, Robert W. P., Hsieh, Samantha A., Donermeyer, David L., Hickey, Christina A., Horvath, Stephen C., Martens, Eric C., Stappenbeck, Thaddeus S., Allen, Paul M.

Journal:

Science Immunology

Year:

2019

File:

PDF, 1.15 MB

2019

92

Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen

Wegorzewska, Marta M., Glowacki, Robert W. P., Hsieh, Samantha A., Donermeyer, David L., Hickey, Christina A., Horvath, Stephen C., Martens, Eric C., Stappenbeck, Thaddeus S., Allen, Paul M.

Journal:

Science Immunology

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

93

Atg14 protects the intestinal epithelium from TNF-triggered villus atrophy

Jung, Haerin, Leal-Ekman, J.Steven, Lu, Qiuhe, Stappenbeck, Thaddeus S.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.74 MB

english, 2019

94

L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams

VanDussen, Kelli L., Sonnek, Naomi M., Stappenbeck, Thaddeus S.

Journal:

Stem Cell Research

Year:

2019

Language:

english

File:

PDF, 2.45 MB

english, 2019

95

Challenges in IBD Research: Preclinical Human IBD Mechanisms

Pizarro, Theresa T, Stappenbeck, Thaddeus S, Rieder, Florian, Rosen, Michael J, Colombel, Jean-Frédéric, Donowitz, Mark, Towne, Jennifer, Mazmanian, Sarkis K, Faith, Jeremiah J, Hodin, Richard A, Garr

Journal:

Inflammatory Bowel Diseases

Year:

2019

Language:

english

File:

PDF, 296 KB

english, 2019

96

Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease

Byers, Derek E., Alexander-Brett, Jennifer, Patel, Anand C., Agapov, Eugene, Dang-Vu, Geoffrey, Jin, Xiaohua, Wu, Kangyun, You, Yingjian, Alevy, Yael, Girard, Jean-Philippe, Stappenbeck, Thaddeus S.,

Journal:

Journal of Clinical Investigation

Year:

2013

Language:

english

File:

PDF, 7.14 MB

english, 2013

97

P128 INHIBITION OF INTESTINAL EPITHELIAL CELL PYROPTOSIS AND ASSOCIATED MUCOSAL BARRIER DEFECTS IS A POTENTIAL THERAPEUTIC MECHANISM OF ACTION FOR MESALAMINE IN IBD

Davis, Elisabeth M., Zhang, Di, Glover, Sarah C., Stappenbeck, Thaddeus, Wang, Shanzhi, Liu, Julia J.

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 169 KB

english, 2019

98

Autophagy proteins are required for club cell structure and function in airways

Malvin, Nicole P, Kern, Justin T, Liu, Ta-Chiang, Brody, Steve L, Stappenbeck, Thaddeus

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2019

File:

PDF, 1.66 MB

2019

99

P128 INHIBITION OF INTESTINAL EPITHELIAL CELL PYROPTOSIS AND ASSOCIATED MUCOSAL BARRIER DEFECTS IS A POTENTIAL THERAPEUTIC MECHANISM OF ACTION FOR MESALAMINE IN IBD

Davis, Elisabeth M., Zhang, Di, Glover, Sarah C., Stappenbeck, Thaddeus, Wang, Shanzhi, Liu, Julia J.

Journal:

Gastroenterology

Year:

2019

File:

PDF, 169 KB

2019

100

Effect of Crohn's Disease Risk Alleles on Enteric Microbiota Marker Paper

Pace, Norman, Mayer, Lloyd, Zhu, Wei, Dietz, David, Boedeker, Edgar, Sartor, R. Balfour, Li, Ellen, Sodergren, Erica, Weinstock, George, Stappenbeck, Thaddeus, Frank, Daniel, Tarr, Phillip, Robertson,

Journal:

Bioentrepreneur

Year:

2010

Language:

english

File:

PDF, 29 KB

english, 2010