Timothy Willson: search on Z-Library

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51

10.1038/3418

Ricote, Mercedes, Li, Andrew C., Willson, Timothy M., Kelly, Carolyn J., Glass, Christopher K.

Journal:

Nature Biotechnology

Year:

1998

Language:

english

File:

PDF, 34 KB

english, 1998

52

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

Pascual, Gabriel, Fong, Amy L., Ogawa, Sumito, Gamliel, Amir, Li, Andrew C., Perissi, Valentina, Rose, David W., Willson, Timothy M., Rosenfeld, Michael G., Glass, Christopher K.

Journal:

Year:

2005

Language:

english

File:

PDF, 503 KB

english, 2005

53

Open access chemical and clinical probes to support drug discovery

Edwards, Aled M, Bountra, Chas, Kerr, David J, Willson, Timothy M

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 142 KB

english, 2009

54

PXR, CAR AND DRUG METABOLISM

Kliewer, Steven A., Willson, Timothy M.

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 541 KB

english, 2002

55

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

Willson, Timothy M., Cobb, Jeffery E., Cowan, David J., Wiethe, Robert W., Correa, Itzela D., Prakash, Shimoga R., Beck, Kelli D., Moore, Linda B., Kliewer, Steven A., Lehmann, Jürgen M.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 176 KB

english, 1996

56

Ligand activation of peroxisome proliferator-activated receptor-β/δ(PPARβ/δ) inhibits cell growth of human N/TERT-1 keratinocytes

Andrew D. Burdick, Moses T. Bility, Elizabeth E. Girroir, Andrew N. Billin, Timothy M. Willson, Frank J. Gonzalez, Jeffrey M. Peters

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

57

Hepatocyte Nuclear Factor 4 Is a Transcription Factor that Constitutively Binds Fatty Acids

G.Bruce Wisely, Ann B. Miller, Roderick G. Davis, Alan D. Thornquest Jr., Robert Johnson, Tim Spitzer, Andrea Sefler, Barry Shearer, John T. Moore, Aaron B. Miller, Timothy M. Willson, Shawn P. Willia

Journal:

Year:

2002

Language:

english

File:

PDF, 457 KB

english, 2002

58

RORα: An Orphan Nuclear Receptor on a High-Cholesterol Diet

Timothy M Willson

Journal:

Year:

2002

Language:

english

File:

PDF, 35 KB

english, 2002

59

On the Lewis-acid-induced addition of allylstannanes to aldehydes: a spectroscopic investigation

Denmark, Scott E., Wilson, Thomas., Willson, Timothy M.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 383 KB

english, 1988

60

Design and Synthesis of an Array of Selective Androgen Receptor Modulators

Willson, Timothy M., Han, Bajin, Turnbull, Philip, Trump, Ryan P., Blanc, Jean-Baptiste E., Stewart, Eugene L., Brown, Peter J., Caivano, Matilde, Gray, David W., Hoekstra, William J.

Journal:

Journal of Combinatorial Chemistry

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

61

Cloning and Characterization of Human Estrogen Receptor β Isoforms

John T. Moore, David D. McKee, Kimberly Slentz-Kesler, Linda B. Moore, Stacey A. Jones, Earnest L. Horne, Jui-Lan Su, Steven A. Kliewer, Jürgen M. Lehmann, Timothy M. Willson

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 926 KB

english, 1998

62

Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole

Timothy J. Van Mouwerik, Cynthia A. Pangallo, James K.V. Willson, Paul H. Fischer

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 740 KB

english, 1987

63

Sweet Dreams for LXR

Mitchell A. Lazar, Timothy M. Willson

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

64

A Structural Basis for Constitutive Activity in the Human CAR/RXRα Heterodimer

Robert X. Xu, Millard H. Lambert, Bruce B. Wisely, Erin N. Warren, Emily E. Weinert, Gregory M. Waitt, Jon D. Williams, Jon L. Collins, Linda B. Moore, Timothy M. Willson, John T. Moore

Journal:

Year:

2004

Language:

english

File:

PDF, 1.15 MB

english, 2004

65

Structural Basis for an Unexpected Mode of SERM-Mediated ER Antagonism

Ya-Ling Wu, Xiaojing Yang, Zhong Ren, Donald P. McDonnell, John D. Norris, Timothy M. Willson, Geoffrey L. Greene

Journal:

Year:

2005

Language:

english

File:

PDF, 720 KB

english, 2005

66

Parallel SUMOylation-Dependent Pathways Mediate Gene- and Signal-Specific Transrepression by LXRs and PPARγ

Serena Ghisletti, Wendy Huang, Sumito Ogawa, Gabriel Pascual, Mu-En Lin, Timothy M. Willson, Michael G. Rosenfeld, Christopher K. Glass

Journal:

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

67

ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar, Brandy Wilkinson, Paige Cramer, Noam Zelcer, Karen Mann, Bruce Lamb, Timothy M. Willson, Jon L. Collins, Jill C. Richardson, Jonathan D. Smith, Thom

Journal:

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

68

Activation of peroxisome proliferator-activated receptor γ inhibits osteoprotegerin gene expression in human aortic smooth muscle cells

Mingui Fu, Jifeng Zhang, Yimin g Lin, Xiaojun Zhu, Timothy M Willson, Yuqing E Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002

69

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A Kliewer, John T Moore, Laura Wade, Jeff L Staudinger, Michael A Watson, Stacey A Jones, David D McKee, Beverly B Oliver, Timothy M Willson, Rolf H Zetterström, Thomas Perlmann, Jürgen M Lehma

Journal:

Year:

1998

Language:

english

File:

PDF, 2.29 MB

english, 1998

70

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Randy K. Bledsoe, Valerie G. Montana, Thomas B. Stanley, Chris J. Delves, Christopher J. Apolito, David D. McKee, Thomas G. Consler, Derek J. Parks, Eugene L. Stewart, Timothy M. Willson, Millard H. L

Journal:

Year:

2002

Language:

english

File:

PDF, 707 KB

english, 2002

71

The nuclear receptor PPARγ-bigger than fat

Steven A Kliewer, Timothy M Willson

Journal:

Current Opinion in Genetics & Development

Year:

1998

Language:

english

File:

PDF, 809 KB

english, 1998

72

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Robert T. Gampe Jr., Valerie G. Montana, Millard H. Lambert, Aaron B. Miller, Randy K. Bledsoe, Michael V. Milburn, Steven A. Kliewer, Timothy M. Willson, H.Eric Xu

Journal:

Year:

2000

Language:

english

File:

PDF, 754 KB

english, 2000

73

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H.Eric Xu, Millard H Lambert, Valerie G Montana, Derek J Parks, Steven G Blanchard, Peter J Brown, Daniel D Sternbach, Jürgen M Lehmann, G.Bruce Wisely, Timothy M Willson, Steven A Kliewer, Michael V

Journal:

Year:

1999

Language:

english

File:

PDF, 333 KB

english, 1999

74

Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR

Li-Zhi Mi, Srikripa Devarakonda, Joel M. Harp, Qing Han, Roberto Pellicciari, Timothy M. Willson, Sepideh Khorasanizadeh, Fraydoon Rastinejad

Journal:

Year:

2003

Language:

english

File:

PDF, 809 KB

english, 2003

75

Identification of Small Molecule Agonists of the Orphan Nuclear Receptors Liver Receptor Homolog-1 and Steroidogenic Factor-1

Whitby, Richard J., Dixon, Sally, Maloney, Patrick R., Delerive, Philippe, Goodwin, Bryan J., Parks, Derek J., Willson, Timothy M.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 49 KB

english, 2006

76

Synthesis and muscarinic activity of quinuclidinyl- and (1-azanorbornyl)pyrazine derivatives

Street, Leslie J., Baker, Raymond, Book, Tracey, Reeve, Austin J., Saunders, John, Willson, Timothy, Marwood, Rosemarie S., Patel, Shailendra, Freedman, Stephen B.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.53 MB

english, 1992

77

SPIE Proceedings [SPIE Microlithography '99 - Santa Clara, CA (Sunday 14 March 1999)] Emerging Lithographic Technologies III - Step and flash imprint lithography: a new approach to high-resolution patterning

Colburn, Matthew, Johnson, Stephen C., Stewart, Michael D., Damle, S., Bailey, Todd C., Choi, Bernard, Wedlake, M., Michaelson, Timothy B., Sreenivasan, S. V., Ekerdt, John G., Willson, C. Grant, Vlad

Year:

1999

Language:

english

File:

PDF, 2.97 MB

english, 1999

78

The importance of chronobiology to drug discovery

Farrow, Stuart N, Solari, Roberto, Willson, Timothy M

Journal:

Expert Opinion on Drug Discovery

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

79

Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure−Activity Relationship of a Series of Body and Side Chain Modified Analogues of Chenodeoxycholic Acid

Pellicciari, Roberto, Costantino, Gabriele, Camaioni, Emidio, Sadeghpour, Bahman M., Entrena, Antonio, Willson, Timothy M., Fiorucci, Stefano, Clerici, Carlo, Gioiello, Antimo

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

80

Isoxazolyl-Serine-Based Agonists of Peroxisome Proliferator-Activated Receptor: Design, Synthesis, and Effects on Cardiomyocyte Differentiation

Wei, Zhi-Liang, Petukhov, Pavel A., Bizik, Fero, Teixeira, Joaquim Cabral, Mercola, Mark, Volpe, Eugene A., Glazer, Robert I., Willson, Timothy M., Kozikowski, Alan P.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

81

On the Intractability of Estrogen-Related Receptor α as a Target for Activation by Small Molecules

Hyatt, Stephen M., Lockamy, Elizabeth L., Stein, Rebecca A., McDonnell, Donald P., Miller, Aaron B., Orband-Miller, Lisa A., Willson, Timothy M., Zuercher, William J.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

82

Comparison of baculovirus-expressed c-Abl and BCR/ABL protein tyrosine kinases

Reynolds, C.Hugh, Willson, Malcolm G., Groffen, John, Heisterkamp, Nora, Peakman, Timothy C., Page, Martin J.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1993

Language:

english

File:

PDF, 1.47 MB

english, 1993

83

The FXR-agonist, 6-ethyl-chenodeoxycholic acid (6-ECDCA), protects against estrogen-induced cholestasis in rats

Fiorucci, Stefano, Clerici, Carlo, Castellani, Danilo, Sabatino, Giuseppe, Antonelli, Elisabetta, Goodwin, Bryan, Willson, Timothy M., Setchell, Kenneth D., Morelli, Antonio, Pellicciari, Roberto

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 268 KB

english, 2003

84

Leptin can Induce Proliferation, Differentiation, and Functional Activation of Hemopoietic Cells

Timothy Gainsford, Tracy A. Willson, Donald Metcalf, Emanuela Handman, Clare McFarlane, Ashley Ng, Nicos A. Nicola, Warren S. Alexander and Douglas J. Hilton

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.45 MB

english, 1996

85

Fatty Acids and Eicosanoids Regulate Gene Expression through Direct Interactions with Peroxisome Proliferator-Activated Receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones, Peter J. Brown, G. Bruce Wisely, Cecilia S. Koble, Pallavi Devchand, Walter Wahli, Timothy M. Willson, James M. Lenhard and Jurgen M. Lehmann

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 968 KB

english, 1997

86

Activation of the Orphan Receptor RIP14 by Retinoids

Ann Marie Zavacki, Jurgen M. Lehmann, Wongi Seol, Timothy M. Willson, Steven A. Kliewer and David D. Moore

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.40 MB

english, 1997

87

Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist

Shearer, Barry G., Steger, David J., Way, James M., Stanley, Thomas B., Lobe, David C., Grillot, Didier A., Iannone, Marie A., Lazar, Mitchell A., Willson, Timothy M., Billin, Andrew N.

Journal:

Molecular Endocrinology

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

88

Evidence of Learning and Risk Orientation during International Crises: The Munich and Polish Cases

Stephen G. Walker, Daniel Bohlin, Robert Boos, David Cownie, Hiroshi Nakajima and Timothy Willson

Journal:

British Journal of Political Science

Year:

1984

Language:

english

File:

PDF, 2.19 MB

english, 1984

89

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα

Grant, Daniel, Yin, Lei, Collins, Jon L., Parks, Derek J., Orband-Miller, Lisa A., Wisely, G. Bruce, Joshi, Shree, Lazar, Mitchell A., Willson, Timothy M., Zuercher, William J.

Journal:

ACS Chemical Biology

Year:

2010

Language:

english

File:

PDF, 438 KB

english, 2010

90

Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)

Whitby, Richard J., Stec, Jozef, Blind, Raymond D., Dixon, Sally, Leesnitzer, Lisa M., Orband-Miller, Lisa A., Williams, Shawn P., Willson, Timothy M., Xu, Robert, Zuercher, William J., Cai, Fang, Ing

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.91 MB

english, 2011

91

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

Pellicciari, Roberto, Fiorucci, Stefano, Camaioni, Emidio, Clerici, Carlo, Costantino, Gabriele, Maloney, Patrick R., Morelli, Antonio, Parks, Derek J., Willson, Timothy M.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 117 KB

english, 2002

92

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic Acid: A Non-Steroidal Estrogen with Functional Selectivity for Bone over Uterus in Rats

Willson, Timothy M., Henke, Brad R., Momtahen, Tanya M., Charifson, Paul S., Batchelor, Kenneth W., Lubahn, Dennis B., Moore, Linda B., Oliver, Beverly B., Sauls, Howard R.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 416 KB

english, 1994

93

Mechanistic and stereochemical divergence in the allylsilane-acetal addition reaction

Denmark, Scott E., Willson, Timothy M.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 290 KB

english, 1989

94

3-(1 H -Indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A Agonists That Demonstrate Oral Activity as Satiety Agents

Henke, Brad R., Willson, Timothy M., Sugg, Elizabeth E., Croom, Dallas K., Dougherty,, Robert W., Queen, Kennedy L., Birkemo, Larry S., Ervin, Gregory N., Grizzle, Mary K., Johnson, Michael F., James,

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 138 KB

english, 1996

95

Discovery of Novel Quinoline-Based Estrogen Receptor Ligands Using Peptide Interaction Profiling

Hoekstra, William J., Patel, Hari S., Liang, Xi, Blanc, Jean-Baptiste E., Heyer, Dennis O., Willson, Timothy M., Iannone, Marie A., Kadwell, Sue H., Miller, Lisa A., Pearce, Kenneth H., Simmons, Cathe

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

96

Further Studies on the Synthesis of 24( S ),25-Epoxycholesterol. A New, Efficient Preparation of Desmosterol

Spencer, Thomas A., Li, Dansu, Russel, Jonathon S., Tomkinson, Nicholas C. O., Willson, Timothy M.

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

97

The origin of stereoselective opening of chiral dioxane and dioxolane acetals: solution structure of their Lewis acid complexes

Denmark, Scott E., Willson, Timothy M., Almstead, Neil G.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 407 KB

english, 1989

98

Efficient, Stereoselective Synthesis of 24( S ),25-Epoxycholesterol

Tomkinson, Nicholas C. O., Willson, Timothy M., Russel, Jonathon S., Spencer, Thomas A.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 71 KB

english, 1998

99

3-[2-( N -Phenylacetamide)]-1,5-benzodiazepines: Orally Active, Binding Selective CCK-A Agonists

Willson, Timothy M., Henke, Brad R., Momtahen, Tanya M., Myers, Peter L., Sugg, Elizabeth E., Unwalla, Rayomand J., Croom, Dallas K., Dougherty, Robert W., Grizzle, Mary K., Johnson, Michael F., Queen

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 103 KB

english, 1996

100

Synthetic approaches to pederin. A synthesis of (�)-benzoylpedamide

Kocienski, Philip, Willson, Timothy M.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 152 KB

english, 1984

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