Timothy J. Vyse: search on Z-Library

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1

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

Nicholas Simpson, Paul A. Gatenby, Anastasia Wilson, Shreya Malik, David A. Fulcher, Stuart G. Tangye, Harinder Manku, Timothy J. Vyse, Giovanna Roncador, Gavin A. Huttley, Christopher C. Goodnow, Car

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

2

Family-based association analysis with ordered categorical phenotypes, covariates and interactions

M. Fazil Baksh, David J. Balding, Timothy J. Vyse, John C. Whittaker

Journal:

Genetic Epidemiology

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

3

Assessment of complement C4 gene copy number using the paralog ratio test

Michelle M.A. Fernando, Lora Boteva, David L. Morris, Bi Zhou, Yee Ling Wu, Marja-Liisa Lokki, Chack Yung Yu, John D. Rioux, Edward J. Hollox, Timothy J. Vyse

Journal:

Year:

2010

Language:

english

File:

PDF, 388 KB

english, 2010

4

Genetic basis of systemic lupus erythematosus

Timothy J Vyse, Brian L Kotzin

Journal:

Current Opinion in Immunology

Year:

1996

Language:

english

File:

PDF, 822 KB

english, 1996

5

Contrasting genetic association ofIL2RAwith SLE and ANCA – associated vasculitis

Edward J Carr, Menna R Clatworthy, Christopher E Lowe, John A Todd, Andrew Wong, Timothy J Vyse, Lavanya Kamesh, Richard A Watts, Paul A Lyons, Kenneth GC Smith

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 543 KB

english, 2009

6

Association of the co-stimulator OX40L with systemic lupus erythematosus

Harinder Manku, Deborah S. Cunninghame Graham, Timothy J. Vyse

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 298 KB

english, 2009

7

Hyper IgE in New Zealand black mice due to a dominant-negative CD23 mutation

Graham Lewis, Eleni Rapsomaniki, Tiphaine Bouriez, Tanya Crockford, Helen Ferry, Robert Rigby, Timothy Vyse, Teresa Lambe, Richard Cornall

Journal:

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

8

Investigation of the HIN200 Locus in UK SLE Families Identifies Novel Copy Number Variants

Michelle M. A. Fernando, Adam J. de Smith, Lachlan Coin, David L. Morris, Philippe Froguel, Jonathan Mangion, Alexandra I. F. Blakemore, Robert R. Graham, Timothy W. Behrens, Timothy J. Vyse

Journal:

Annals of Human Genetics

Year:

2011

Language:

english

File:

PDF, 945 KB

english, 2011

9

Genetic Contributions to Lupus-like Disease in (NZB×NZW)F1 Mice

CHARLES G. DRAKE, STEPHEN J. ROZZO, TIMOTHY J. VYSE, ED PALMER, BRIAN L. KOTZIN

Journal:

Immunological Reviews

Year:

1995

Language:

english

File:

PDF, 7.58 MB

english, 1995

10

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

Morris, David L, Roberts, Amy L, Witherden, Abigail S, Tarzi, Ruth, Barros, Paula, Whittaker, John C, Cook, Terence H, Aitman, Timothy J, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 335 KB

english, 2010

11

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

Aitman, Timothy J., Dong, Rong, Vyse, Timothy J., Norsworthy, Penny J., Johnson, Michelle D., Smith, Jennifer, Mangion, Jonathan, Roberton-Lowe, Cheri, Marshall, Amy J., Petretto, Enrico

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

12

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Harley, John B, Alarcón-Riquelme, Marta E, Criswell, Lindsey A, Jacob, Chaim O, Kimberly, Robert P, Moser, Kathy L, Tsao, Betty P, Vyse, Timothy J, Langefeld, Carl D

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

13

Narcolepsy and the T-cell receptor

Vyse, Timothy J

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

14

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

Lee-Kirsch, Min Ae, Gong, Maolian, Chowdhury, Dipanjan, Senenko, Lydia, Engel, Kerstin, Lee, Young-Ae, de Silva, Udesh, Bailey, Suzanna L, Witte, Torsten, Vyse, Timothy J

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

15

Haplotype structure of TNFRSF5-TNFSF5 (CD40–CD40L) and association analysis in systemic lupus erythematosus

Chadha, Sapna, Miller, Katie, Farwell, Lisa, Lightstone, Liz B, Daly, Mark J, Rioux, John D, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 188 KB

english, 2005

16

Haplotype analysis of tumour necrosis factor receptor genes in 1p36: no evidence for association with systemic lupus erythematosus

Chadha, Sapna, Miller, Katie, Farwell, Lisa, Sacks, Steven, Daly, Mark J, Rioux, John D, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

17

The Wolf at the Door

Uttenthal, Benjamin J., Layton, D. Mark, Vyse, Timothy J., Schreiber, Benjamin E.

Journal:

New England Journal of Medicine

Year:

2012

Language:

english

File:

PDF, 578 KB

english, 2012

18

Genetically Determined Partial Complement C4 Deficiency States Are Not Independent Risk Factors for SLE in UK and Spanish Populations

Lora Boteva, David L. Morris, Josefina Cortés-Hernández, Javier Martin, Timothy J. Vyse, Michelle M.A. Fernando

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 380 KB

english, 2012

19

The Molecular Basis by Which Polymorphism in the OX40L Gene Predisposes to SLE

Harinder Manku, Deborah Cunninghame Graham, Robert R. Graham, Timothy W. Behrens, Timothy W. Behrens, David Althshuler, Timothy J. Vyse

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

20

Sa.54. Positional Identification of Integrin- αMβ2 (ITGAM) as a Susceptibility Gene for Systematic Lupus Erythematosus (SLE)

Swapan Nath, Shizhong Han, Xana Kim-Howard, Harshal Deshmukh, Parvathi Viswanathan, Gail Bruner, Jennifer Kelly, Gary Gilkeson, Rodger McEver, Robert Kimberly, Timothy Vyse, Wei Chen, Cheng Zhu, Marta

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

21

Sa.9. Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus

Amr Sawalha, Ryan Webb, Shizhong Han, Jennifer Kelly, Kenneth Kaufman, Robert Kimberly, Marta Alarcón-Riquelme, Judith James, Timothy Vyse, Gary Gilkeson, Chan-Bum Choi, Hal Scofield, Sang-Cheol Bae,

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

22

F.33. The IMAGEN Consortium: A High-density SNP Map of the MHC in Lupus Identifies Multiple Independent Disease-associated Variants

Michelle Fernando, Philippe Goyette, Jorge Oksenberg, Kathy Moser, Patrick Gaffney, Tim Behrens, Stephen Hauser, John Rioux, Timothy Vyse

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

23

F.28. Evidence for Both Quantitative and Qualitative Risk at the FcγR3B Locus in Systemic Lupus Erythematosus (SLE)

David Morris, Amy Roberts, Abi Witherden, John Whittaker, Timothy Aitman, Timothy Vyse

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

24

Genetic Analysis of Autoimmune Disease

Timothy J Vyse, John A Todd

Journal:

Year:

1996

Language:

english

File:

PDF, 895 KB

english, 1996

25

Evidence for an Interferon-Inducible Gene, Ifi202, in the Susceptibility to Systemic Lupus

Stephen J Rozzo, John D Allard, Divaker Choubey, Timothy J Vyse, Shozo Izui, Gary Peltz, Brian L Kotzin

Journal:

Year:

2001

Language:

english

File:

PDF, 183 KB

english, 2001

26

Sa.31. A Genome-wide Association Scan in Women with Systemic Lupus Erythematosus Identifies Risk Variants in ITGAM, PXK, KIAA1542 and Other Loci and Confirms Multiple Loci Contributing to Disease Susceptibility

John Harley, Marta Alarcón-Riquelme, Lindsey Criswell, Chaim Jacob, Robert Kimberly, Kathy Moser, Betty Tsao, Timothy Vyse, Carl Langefeld

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

27

Thymic Microenvironment and NZB Mice: The Abnormal Thymic Microenvironment of New Zealand Mice Correlates with Immunopathology

Yuichi Takeoka, Nobuhisa Taguchi, Brian L. Kotzin, Sean Bennett, Timothy J. Vyse, Richard L. Boyd, Mitsuru Naiki, Jin-emon Konishi, Aftab A. Ansari, Leonard D. Shultz, M.Eric Gershwin

Journal:

Clinical Immunology

Year:

1999

Language:

english

File:

PDF, 173 KB

english, 1999

28

Models of systemic lupus erythematosus

Robert J. Rigby, Timothy J. Vyse

Journal:

Drug Discovery Today: Disease Models

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

29

Genetics of rheumatic disease

Alex Clarke, Timothy J Vyse

Journal:

Arthritis Research & Therapy

Year:

2009

Language:

english

File:

PDF, 146 KB

english, 2009

30

Three Sgp loci act independently as well as synergistically to elevate the expression of specific endogenous retroviruses implicated in murine lupus

Ito, Kiyoaki, Baudino, Lucie, Kihara, Masao, Leroy, Valérie, Vyse, Timothy J., Evans, Leonard H., Izui, Shozo

Journal:

Journal of Autoimmunity

Year:

2013

Language:

english

File:

PDF, 326 KB

english, 2013

31

Effect of Genetic Background on the Contribution of New Zealand Black Loci to Autoimmune Lupus Nephritis

Stephen J. Rozzo, Timothy J. Vyse, Charles G. Drake and Brian L. Kotzin

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 847 KB

english, 1996

32

Control of Separate Pathogenic Autoantibody Responses Marks MHC Gene Contributions to Murine Lupus

Timothy J. Vyse, Richard K. Halterman, Stephen J. Rozzo, Shozo Izui and Brian L. Kotzin

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.34 MB

english, 1999

33

Resequencing the susceptibility gene,ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

Roberts, Amy L, Thomas, Ellen RA, Bhosle, Shriram, Game, Laurence, Obraztsova, Olga, Aitman, Timothy J, Vyse, Timothy J, Rhodes, Benjamin

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 505 KB

english, 2014

34

C-reactive protein in rheumatology: biology and genetics

Rhodes, Benjamin, Fürnrohr, Barbara G., Vyse, Timothy J.

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2011

Language:

english

File:

PDF, 583 KB

english, 2011

35

The genetics of lupus: a functional perspective

Sandra G Guerra,Timothy J Vyse…

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 447 KB

english, 2012

36

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 2.86 MB

english, 2015

37

UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases

Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Boeltz, Sebastian, Gordon, Patrick A., Spector, Timothy D., Lehner, Paul J., Walczak, Henning, Vyse, Timothy J.

Journal:

The American Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

38

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

Willcocks, Lisa C., Carr, Edward J., Niederer, Heather A., Rayner, Tim F., Williams, Thomas N., Yang, Wanling, Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Vyse, Timothy J., Lau, Yu Lung, L

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 162 KB

english, 2010

39

Analysis of systemic lupus erythematosus sub-phenotype data for genetic association

Morris, David L., Vyse, Timothy J.

Journal:

Current Opinion in Rheumatology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

40

Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus

Lewis, Myles, Vyse, Simon, Shields, Adrian, Boeltz, Sebastian, Gordon, Patrick, Spector, Timothy, Lehner, Paul, Walczak, Henning, Vyse, Timothy

Journal:

Year:

2015

Language:

english

File:

PDF, 64 KB

english, 2015

41

Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice

Bygrave, Anne E., Rose, Kirsten L., Cortes-Hernandez, Josefina, Warren, Joanna, Rigby, Robert J., Cook, H. Terence, Walport, Mark J., Vyse, Timothy J., Botto, Marina

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

42

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip L., Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D., Fisher, Elizabeth M. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

43

A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation

Rhodes, Benjamin, Merriman, Marilyn E., Harrison, Andrew, Nissen, Michael J., Smith, Malcolm, Stamp, Lisa, Steer, Sophia, Merriman, Tony R., Vyse, Timothy J., Hingorani, Aroon

Journal:

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

44

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

Cunninghame Graham, Deborah S., Morris, David L., Bhangale, Tushar R., Criswell, Lindsey A., Syvänen, Ann-Christine, Rönnblom, Lars, Behrens, Timothy W., Graham, Robert R., Vyse, Timothy J., McCarthy,

Journal:

Year:

2011

Language:

english

File:

PDF, 686 KB

english, 2011

45

Identification of Two Independent Risk Factors for Lupus within the MHC in United Kingdom Families

Fernando, Michelle M. A., Stevens, Christine R., Sabeti, Pardis C., Walsh, Emily C., McWhinnie, Alasdair J. M., Shah, Anila, Green, Todd, Rioux, John D., Vyse, Timothy J.

Journal:

Year:

2007

Language:

english

File:

PDF, 842 KB

english, 2007

46

Using genetics to deliver personalized SLE therapy—a realistic prospect?

Rhodes, Benjamin, Vyse, Timothy J.

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2010

Language:

english

File:

PDF, 210 KB

english, 2010

47

Genetics: Unraveling the genetics of autoimmune disease

Vyse, Timothy J.

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

48

A defunctioning polymorphism inFCGR2Bis associated with protection against malaria but susceptibility to systemic lupus erythematosus

Lisa C. Willcocks, Edward J. Carr, Heather A. Niederer, Tim F. Rayner, Thomas N. Williams, Wanling Yang, J. Anthony G. Scott, Britta C. Urban, Norbert Peshu, Timothy J. Vyse, Yu Lung Lau, Paul A. Lyon

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

49

What does the immunogenetic basis of rheumatoid arthritis teach us about the immunobiology of the disease?

Gorman, Claire, Vyse, Timothy, Cope, Andrew

Journal:

Expert Review of Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 707 KB

english, 2006

50

Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1

Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Zou, Lu, Khamashta, Munther, Gordon, Patrick A., Pitzalis, Costantino, Vyse, Timothy J., D’Cruz, David P.

Journal:

Arthritis Research & Therapy

Year:

2016

Language:

english

File:

PDF, 788 KB

english, 2016

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