Tomohisa Kuzuyama†: search on Z-Library

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1

Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases

Seung-Young Kim, Ping Zhao, Masayuki Igarashi, Ryuichi Sawa, Takeo Tomita, Makoto Nishiyama, Tomohisa Kuzuyama

Journal:

Chemistry & Biology

Year:

2009

Language:

english

File:

PDF, 663 KB

english, 2009

2

Cloning and Heterologous Expression of the Aurachin RE Biosynthesis Gene Cluster Afford a New Cytochrome P450 for Quinoline N-Hydroxylation

Kitagawa, Wataru, Ozaki, Taro, Nishioka, Taiki, Yasutake, Yoshiaki, Hata, Miyako, Nishiyama, Makoto, Kuzuyama, Tomohisa, Tamura, Tomohiro

Journal:

Year:

2013

Language:

english

File:

PDF, 575 KB

english, 2013

3

Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase

Hayashi, Daisuke, Kato, Nobuo, Kuzuyama, Tomohisa, Sato, Yasuo, Ohkanda, Junko

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

4

Cyclolavandulyl Skeleton Biosynthesis via Both Condensation and Cyclization Catalyzed by an Unprecedented Member of the cis -Isoprenyl Diphosphate Synthase Superfamily

Ozaki, Taro, Zhao, Ping, Shinada, Tetsuro, Nishiyama, Makoto, Kuzuyama, Tomohisa

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

5

Diversity of the biosynthesis of the isoprene units

Kuzuyama, Tomohisa, Seto, Haruo

Journal:

Natural Product Reports

Year:

2003

Language:

english

File:

PDF, 366 KB

english, 2003

6

Bioactive natural products with carbon–phosphorus bonds and their biosynthesis

Seto, Haruo, Kuzuyama, Tomohisa, Seto, Haruo, Kuzuyama, Tomohisa

Journal:

Natural Product Reports

Year:

1999

Language:

english

File:

PDF, 151 KB

english, 1999

7

Cloning of a Gene Cluster Encoding Enzymes Responsible for the Mevalonate Pathway from a Terpenoid-antibiotic-producing Streptomyces Strain

HAMANO, Yoshimitsu, DAIRI, Tohru, YAMAMOTO, Masahiro, KAWASAKI, Takashi, KANEDA, Kazuhide, KUZUYAMA, Tomohisa, ITOH, Nobuya, SETO, Haruo

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2001

Language:

english

File:

PDF, 1.46 MB

english, 2001

8

Genome mining for sesterterpenes using bifunctional terpene synthases reveals a unified intermediate of di/sesterterpenes

Ye, Ying, Minami, Atsushi, Mándi, Attila, Liu, Chengwei, Taniguchi, Tohru, Kuzuyama, Tomohisa, Monde, Kenji, Gomi, Katsuya, Oikawa, Hideaki

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 583 KB

english, 2015

9

Novel features of the ISC machinery revealed by characterization of Escherichia coli mutants that survive without iron-sulfur clusters

Tanaka, Naoyuki, Kanazawa, Miaki, Tonosaki, Keitaro, Yokoyama, Nao, Kuzuyama, Tomohisa, Takahashi, Yasuhiro

Journal:

Molecular Microbiology

Year:

2016

Language:

english

File:

PDF, 492 KB

english, 2016

10

Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces

Hasebe, Fumihito, Matsuda, Kenichi, Shiraishi, Taro, Futamura, Yushi, Nakano, Takeshi, Tomita, Takeo, Ishigami, Ken, Taka, Hikari, Mineki, Reiko, Fujimura, Tsutomu, Osada, Hiroyuki, Kuzuyama, Tomohisa

Journal:

Nature Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

11

Metabolic engineering of flavonoids with prenyltransferase and chalcone isomerase genes in tomato fruits

Kawasaki, Takashi, Koeduka, Takao, Sugiyama, Akifumi, Sasaki, Kanako, Linley, Philip J., Shitan, Nobukazu, Kumano, Takuto, Yamamoto, Hideaki, Ezura, Hiroshi, Kuzuyama, Tomohisa, Yazaki, Kazufumi

Journal:

Plant Biotechnology

Year:

2014

Language:

english

File:

PDF, 481 KB

english, 2014

12

Structural and Mechanistic Insights into Terpene Synthases that Catalyze the Irregular Non-head-to-tail Coupling of Prenyl Substrates

Kobayashi, Masaya, Kuzuyama, Tomohisa

Journal:

Year:

2018

Language:

english

File:

PDF, 5.33 MB

english, 2018

13

Mechanistic Studies of HPP Epoxidase: Configuration of the Substrate Governs Its Enzymatic Fate

Zongbao Zhao, Pinghua Liu, Kazuo Murakami, Tomohisa Kuzuyama, Haruo Seto, Hung-wen Liu

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

14

Mechanistic Studies of HPP Epoxidase: Configuration of the Substrate Governs Its Enzymatic Fate

Zongbao Zhao, Pinghua Liu, Kazuo Murakami, Tomohisa Kuzuyama, Haruo Seto, Hung-wen Liu

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

15

ChemInform Abstract: Bioactive Natural Products with Carbon—Phosphorus Bonds and Their Biosynthesis

Haruo Seto, Tomohisa Kuzuyama

Journal:

Year:

2000

File:

PDF, 24 KB

2000

16

ChemInform Abstract: Studies on the Nonmevalonate Pathway: Formation of 2-C-Methyl-D-erythritol 2,4-Cyclodiphosphate from 2-Phospho-4-(cytidine 5′-Diphospho)-2-C-methyl-D-erythritol.

Motoki Takagi, Tomohisa Kuzuyama, Kazuhide Kaneda, Hiroyuki Watanabe, Tohru Dairi, Haruo Seto

Journal:

Year:

2000

File:

PDF, 29 KB

2000

17

Diversity of the Biosynthesis of the Isoprene Units

Tomohisa Kuzuyama, Haruo Seto

Journal:

Year:

2003

File:

PDF, 4 KB

2003

18

Biosynthetic Studies of Versipelostatin, a Novel 17-Membered α-Tetronic Acid Involved Macrocyclic Compound Isolated from Streptomyces versipellis.

Shuhei Chijiwa, Hae-Ryong Park, Kazuo Furihata, Masahiro Ogata, Toyoshige Endo, Tomohisa Kuzuyama, Yoichi Hayakawa, Kazuo Shin-ya

Journal:

Year:

2003

File:

PDF, 56 KB

2003

19

ChemInform Abstract: Convergent Strategies in Biosynthesis

Tohru Dairi, Tomohisa Kuzuyama, Makoto Nishiyama, Isao Fujii

Journal:

Year:

2011

File:

PDF, 18 KB

2011

20

Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities

Takuto Kumano, Stéphane B. Richard, Joseph P. Noel, Makoto Nishiyama, Tomohisa Kuzuyama

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

21

Cloning and functional characterization of 2-C-methyl-d-erythritol 4-phosphate cytidyltransferase (GbMECT) gene from Ginkgo biloba

Sang-Min Kim, Tomohisa Kuzuyama, Yung-Jin Chang, Hyung-Jin Kwon, Soo-Un Kim

Journal:

Year:

2006

Language:

english

File:

PDF, 527 KB

english, 2006

22

Preparation of highly deuterated zeaxanthin, lycopene, and β-carotene from fully deuterated mevalonate using engineered Escherichia coli

Tadashi Eguchi, Yasumasa Dekishima, Hideki Aizawa, Hideyuki Tamegai, Katsumi Kakinuma, Norihiko Misawa, Tomohisa Kuzuyama, Haruo Seto

Journal:

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

23

Studies on the nonmevalonate pathway: conversion of 4-(cytidine 5′-diphospho)-2-C-methyl-d-erythritol to its 2-phospho derivative by 4-(cytidine 5′-diphospho)-2-C-methyl-d-erythritol kinase

Tomohisa Kuzuyama, Motoki Takagi †, Kazuhide Kaneda, Hiroyuki Watanabe, Tohru Dairi, Haruo Seto

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

24

Biosynthetic studies of versipelostatin, a novel 17-membered α-tetronic acid involved macrocyclic compound isolated from Streptomyces versipellis

Shuhei Chijiwa, Hae-Ryong Park, Kazuo Furihata, Masahiro Ogata, Toyoshige Endo, Tomohisa Kuzuyama, Yoichi Hayakawa, Kazuo Shin-ya

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 161 KB

english, 2003

25

Direct formation of 2-C-methyl-d-erythritol 4-phosphate from 1-deoxy-d-xylulose 5-phosphate by 1-deoxy-d-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate

Tomohisa Kuzuyama, Shunji Takahashi, Hiroyuki Watanabe, Haruo Seto

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

26

Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis

Tomohisa Kuzuyama, Tomohiro Shimizu, Shunji Takahashi, Haruo Seto

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 231 KB

english, 1998

27

Formation of 4-(cytidine 5′-diphospho)-2-C-methyl-d-erythritol from 2-C-methyl-d-erythritol 4-phosphate by 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase, a new enzyme in the nonmevalonate pathway

Tomohisa Kuzuyama, Motoki Takagi†, Kazuhide Kaneda, Tohru Dairi, Haruo Seto

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

28

Mechanism for multiple-substrates recognition of α-aminoadipate aminotransferase from Thermus thermophilus

Takeo Tomita, Tomoharu Miyagawa, Takashi Miyazaki, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 640 KB

english, 2009

29

Cloning and nucleotide sequence of fosfomycin biosynthetic genes ofStreptomyces wedmorensis

Tomomi Hidaka, Masao Goda, Tomohisa Kuzuyama, Naomi Takei, Makoto Hidaka, Haruo Seto

Journal:

Molecular Genetics and Genomics

Year:

1995

Language:

english

File:

PDF, 781 KB

english, 1995

30

Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineeredEscherichia coli

Hisashi Harada, Fengnian Yu, Sho Okamoto, Tomohisa Kuzuyama, Ryutaro Utsumi, Norihiko Misawa

Journal:

Applied Microbiology and Biotechnology

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

31

Cloning and characterization of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate synthase (MECS) gene fromGinkgo biloba

Sang-Min Kim, Tomohisa Kuzuyama, Yung-Jin Chang, Soo-Un Kim

Journal:

Plant Cell Reports

Year:

2006

Language:

english

File:

PDF, 420 KB

english, 2006

32

Antisense and chemical suppression of the nonmevalonate pathway affectsent-kaurene biosynthesis inArabidopsis

Kazunori Okada, Hiroshi Kawaide, Tomohisa Kuzuyama, Haruo Seto, Ian S. Curtis, Yuji Kamiya

Journal:

Year:

2002

Language:

english

File:

PDF, 210 KB

english, 2002

33

1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (IDS) is encoded by multicopy genes in gymnospermsGinkgo bilobaandPinus taeda

Sang-Min Kim, Tomohisa Kuzuyama, Akio Kobayashi, Tomoki Sando, Yung-Jin Chang, Soo-Un Kim

Journal:

Year:

2008

Language:

english

File:

PDF, 787 KB

english, 2008

34

Two copies of 4-(cytidine 5′-diphospho)-2-C-methyl-d-erythritol kinase (CMK) gene inGinkgo biloba: molecular cloning and functional characterization

Sang-Min Kim, Yeon-Bok Kim, Tomohisa Kuzuyama, Soo-Un Kim

Journal:

Year:

2008

Language:

english

File:

PDF, 622 KB

english, 2008

35

Elicitor induced activation of the methylerythritol phosphate pathway toward phytoalexins biosynthesis in rice

Atsushi Okada, Takafumi Shimizu, Kazunori Okada, Tomohisa Kuzuyama, Jinichiro Koga, Naoto Shibuya, Hideaki Nojiri, Hisakazu Yamane

Journal:

Plant Molecular Biology

Year:

2007

Language:

english

File:

PDF, 706 KB

english, 2007

36

Studies on the nonmevalonate pathway: formation of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate from 2-phospho-4-(cytidine 5′-diphospho)-2-C-methyl-d-erythritol

Motoki Takagi, Tomohisa Kuzuyama†, Kazuhide Kaneda, Hiroyuki Watanabe, Tohru Dairi, Haruo Seto

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 92 KB

english, 2000

37

Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase from Thermus thermophilus

Ayako Yoshida, Takeo Tomita, Hidetoshi Kono, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Year:

2009

Language:

english

File:

PDF, 969 KB

english, 2009

38

NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids

Ozaki, Taro, Mishima, Satoshi, Nishiyama, Makoto, Kuzuyama, Tomohisa

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 282 KB

english, 2009

39

The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae

Matsue, Yukiko, Mizuno, Hiroko, Tomita, Takeo, Asami, Tadao, Nishiyama, Makoto, Kuzuyama, Tomohisa

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 390 KB

english, 2010

40

Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

Kuzuyama, Tomohisa, Noel, Joseph P., Richard, Stéphane B.

Journal:

Year:

2005

Language:

english

File:

PDF, 329 KB

english, 2005

41

Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus

Horie, Akira, Tomita, Takeo, Saiki, Asako, Kono, Hidetoshi, Taka, Hikari, Mineki, Reiko, Fujimura, Tsutomu, Nishiyama, Chiharu, Kuzuyama, Tomohisa, Nishiyama, Makoto

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

42

Convergent strategies in biosynthesis

Dairi, Tohru, Kuzuyama, Tomohisa, Nishiyama, Makoto, Fujii, Isao

Journal:

Natural Product Reports

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

43

Microbial glucosylation of flavonols by Cunninghamella echinulata

Shunichi Miyakoshi, Shun Azami, Tomohisa Kuzuyama

Journal:

Journal of Bioscience and Bioengineering

Year:

2010

Language:

english

File:

PDF, 163 KB

english, 2010

44

Sequence of a P-.methyltransferase-encoding gene isolated from a bialaphos-producing Streptomyces hygroscopicus

Tomomi Hidaka, Makoto Hidaka, Tomohisa Kuzuyama, Haruo Seto

Journal:

Year:

1995

Language:

english

File:

PDF, 200 KB

english, 1995

45

Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H)

Takeo Tomita, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 849 KB

english, 2005

46

Corrigendum to “Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H)” [Biochem. Biophys. Res. Commun. 334 (2005) 613–618]

Takeo Tomita, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

File:

PDF, 57 KB

2005

47

Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant

Takeo Tomita, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 280 KB

english, 2006

48

Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in α-aminoadipate aminotransferase from Thermus thermophilus

Takuya Ouchi, Takeo Tomita, Tomoharu Miyagawa, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 656 KB

english, 2009

49

fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis

Kia-Joo Puan, Hong Wang, Tohru Dairi, Tomohisa Kuzuyama, Craig T. Morita

Journal:

Year:

2005

Language:

english

File:

PDF, 190 KB

english, 2005

50

Structural Insight into Concerted Inhibition of α2β2-Type Aspartate Kinase from Corynebacterium glutamicum

Ayako Yoshida, Takeo Tomita, Takeshi Kurihara, Shinya Fushinobu, Tomohisa Kuzuyama, Makoto Nishiyama

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.43 MB

english, 2007

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