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51

Resolving the Gatekeeper Conundrum

Grumbach, Kevin, Selby, Joe V., Damberg, Cheryl, Bindman, Andrew B., Quesenberry, Jr, Charles, Truman, Alison, Uratsu, Connie

Journal:

JAMA The Journal of the American Medical Association

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

52

Plasmid carriage can limit bacteria–phage coevolution

Harrison, Ellie, Truman, Julie, Wright, Rosanna, Spiers, Andrew J., Paterson, Steve, Brockhurst, Michael A.

Journal:

Biology Letters

Year:

2015

Language:

english

File:

PDF, 442 KB

english, 2015

53

The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to Zn(II)

Zarkan, Ashraf, Macklyne, Heather-Rose, Truman, Andrew W., Hesketh, Andrew R., Hong, Hee-Jeon

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

54

Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics

Crone, William J. K., Vior, Natalia M., Santos-Aberturas, Javier, Schmitz, Lukas G., Leeper, Finian J., Truman, Andrew W.

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 1.72 MB

english, 2016

55

1708

Fletcher, John, Graybill, John, Alphonso, Carlos, Milling, Truman, Cap, Andrew, Akers, Kevin

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 400 KB

english, 2016

56

A genomics-based approach identifies a thioviridamide-like compound with selective anticancer activity

Frattaruolo, Luca, Lacret, Rodney, Cappello, Anna Rita, Truman, Andrew W

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

57

Cracking the Chaperone Code: Cellular Roles for Hsp70 Phosphorylation

Nitika,, Truman, Andrew W.

Journal:

Trends in Biochemical Sciences

Year:

2017

Language:

english

File:

PDF, 770 KB

english, 2017

58

Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer

Dushukyan, Natela, Dunn, Diana M., Sager, Rebecca A., Woodford, Mark R., Loiselle, David R., Daneshvar, Michael, Baker-Williams, Alexander J., Chisholm, John D., Truman, Andrew W., Vaughan, Cara K., H

Journal:

Year:

2017

Language:

english

File:

PDF, 3.65 MB

english, 2017

59

Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme

Franz, Laura, Adam, Sebastian, Santos-Aberturas, Javier, Truman, Andrew W., Koehnke, Jesko

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 920 KB

english, 2017

60

Discovery and biosynthesis of the antibiotic bicyclomycin in distant bacterial classes

Vior, Natalia M., Lacret, Rodney, Chandra, Govind, Dorai-Raj, Siobhán, Trick, Martin, Truman, Andrew W.

Journal:

Applied and Environmental Microbiology

Year:

2018

Language:

english

File:

PDF, 4.67 MB

english, 2018

61

Rapid and robust yeast-mediated pathway refactoring generates multiple new bottromycin-related metabolites

Eyles, Tom Hayon, Vior, Natalia Miguel, Truman, Andrew W

Journal:

ACS Synthetic Biology

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

62

Characterizing functional differences in sea anemone Hsp70 isoforms using budding yeast

Waller, Shawn J., Knighton, Laura E., Crabtree, Lenora M., Perkins, Abigail L., Reitzel, Adam M., Truman, Andrew W.

Journal:

Cell Stress and Chaperones

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

63

ChemInform Abstract: Cyclization Mechanisms in the Biosynthesis of Ribosomally Synthesized and Post-Translationally Modified Peptides

Truman, Andrew W.

Journal:

Year:

2016

File:

PDF, 14 KB

2016

64

Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: potential uses and limitations of this approach

Millson, Stefan H., Truman, Andrew W., Wolfram, Francis, King, Victoria, Panaretou, Barry, Prodromou, Chrisostomos, Pearl, Laurence H., Piper, Peter W.

Journal:

Cell Stress and Chaperones

Year:

2004

Language:

english

File:

PDF, 392 KB

english, 2004

65

PD46-11 PHOSPHORYLATION AND UBIQUITINATION REGULATE PROTEIN PHOSPHATASE-5 ACTIVITY AND ITS PROSURVIVAL ROLE IN KIDNEY CANCER

Dushukyan, Natela, Daneshvar, Michael, Sager, Rebecca, Woodford, Mark, Baker-Williams, Alexander, Chisholm, John, Loiselle, David, Truman, Andrew, Haystead, Timothy, Shapiro, Oleg, Bourboulia, Dimitra

Journal:

The Journal of Urology

Year:

2018

Language:

english

File:

PDF, 38 KB

english, 2018

66

Cyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptides

Truman, Andrew W

Journal:

Beilstein Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

67

Genetic analysis of Hsp70 phosphorylation sites reveals a role in Candida albicans cell and colony morphogenesis

Weissman, Ziva, Pinsky, Mariel, Wolfgeher, Donald J., Kron, Stephen J., Truman, Andrew W., Kornitzer, Daniel

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

68

Post-fire forest regeneration shows limited climate tracking and potential for drought-induced type conversion

Young, Derek J. N., Werner, Chhaya M., Welch, Kevin R., Young, Truman P., Safford, Hugh D., Latimer, Andrew M.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.31 MB

english, 2018

69

Novel insights into molecular chaperone regulation of ribonucleotide reductase

Knighton, Laura E., Delgado, Lena E., Truman, Andrew W.

Journal:

Current Genetics

Year:

2018

Language:

english

File:

PDF, 914 KB

english, 2018

70

Brain glutamate, GABA , and glutamine levels and associations with recent drinking in treatment‐naïve individuals with Alcohol Use Disorder versus light drinkers

Prisciandaro, James J., Schacht, Joseph P., Prescot, Andrew P., Renshaw, Perry F., Brown, Truman R., Anton, Raymond F.

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2018

Language:

english

File:

PDF, 377 KB

english, 2018

71

Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool

Santos-Aberturas, Javier, Chandra, Govind, Frattaruolo, Luca, Lacret, Rodney, Pham, Thu H, Vior, Natalia M, Eyles, Tom H, Truman, Andrew W

Journal:

Nucleic Acids Research

Year:

2019

File:

PDF, 5.18 MB

2019

72

Results From the First Multicenter, Open-label, Phase IIIb Study Investigating the Combination of Pertuzumab With Subcutaneous Trastuzumab and a Taxane in Patients With HER2-positive Metastatic Breast Cancer (SAPPHIRE)

Woodward, Natasha, De Boer, Richard H., Redfern, Andrew, White, Michelle, Young, Jennifer, Truman, Matt, Beith, Jane

Journal:

Clinical Breast Cancer

Year:

2019

File:

PDF, 630 KB

2019

73

Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool

Santos-Aberturas, Javier, Chandra, Govind, Frattaruolo, Luca, Lacret, Rodney, Pham, Thu H, Vior, Natalia M, Eyles, Tom H, Truman, Andrew W

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 5.18 MB

english, 2019

74

Results From the First Multicenter, Open-label, Phase IIIb Study Investigating the Combination of Pertuzumab With Subcutaneous Trastuzumab and a Taxane in Patients With HER2-positive Metastatic Breast Cancer (SAPPHIRE)

Woodward, Natasha, De Boer, Richard H., Redfern, Andrew, White, Michelle, Young, Jennifer, Truman, Matt, Beith, Jane

Journal:

Clinical Breast Cancer

Year:

2019

Language:

english

File:

PDF, 630 KB

english, 2019

75

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

Jain, Siddhant U., Do, Truman J., Lund, Peder J., Rashoff, Andrew Q., Diehl, Katharine L., Cieslik, Marcin, Bajic, Andrea, Juretic, Nikoleta, Deshmukh, Shriya, Venneti, Sriram, Muir, Tom W., Garcia, B

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 3.59 MB

english, 2019

76

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

Jain, Siddhant U., Do, Truman J., Lund, Peder J., Rashoff, Andrew Q., Diehl, Katharine L., Cieslik, Marcin, Bajic, Andrea, Juretic, Nikoleta, Deshmukh, Shriya, Venneti, Sriram, Muir, Tom W., Garcia, B

Journal:

Nature Communications

Year:

2019

File:

PDF, 3.59 MB

2019

77

Dynamic remodeling of the interactomes of Nematostella vectensis Hsp70 isoforms under heat shock

Knighton, Laura E., Nitika,, Waller, Shawn J., Strom, Owen, Wolfgeher, Donald, Reitzel, Adam M., Truman, Andrew W.

Journal:

Journal of Proteomics

Year:

2019

Language:

english

File:

PDF, 2.87 MB

english, 2019

78

Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer

Ricco, Natalia, Flor, Amy, Wolfgeher, Don, Efimova, Elena V., Ramamurthy, Aishwarya, Appelbe, Oliver K., Brinkman, Jacqueline, Truman, Andrew W., Spiotto, Michael T., Kron, Stephen J.

Journal:

Molecular Oncology

Year:

2019

File:

PDF, 3.62 MB

2019

79

Dynamic remodeling of the interactomes of Nematostella vectensis Hsp70 isoforms under heat shock

Knighton, Laura E., Nitika,, Waller, Shawn J., Strom, Owen, Wolfgeher, Donald, Reitzel, Adam M., Truman, Andrew W.

Journal:

Journal of Proteomics

Year:

2019

File:

PDF, 2.87 MB

2019

80

Intraindividual changes in brain GABA, glutamate, and glutamine during monitored abstinence from alcohol in treatment‐naive individuals with alcohol use disorder

Prisciandaro, James J., Schacht, Joseph P., Prescot, Andrew P., Brenner, Helena M., Renshaw, Perry F., Brown, Truman R., Anton, Raymond F.

Journal:

Addiction Biology

Year:

2019

Language:

english

File:

PDF, 699 KB

english, 2019

81

Oligomerization of Hsp70: Current Perspectives on Regulation and Function

Takakuwa, Jade E., Nitika,, Knighton, Laura E., Truman, Andrew W.

Journal:

Frontiers in Molecular Biosciences

Year:

2019

Language:

english

File:

PDF, 981 KB

english, 2019

82

Oligomerization of Hsp70: Current Perspectives on Regulation and Function

Takakuwa, Jade E., Nitika,, Knighton, Laura E., Truman, Andrew W.

Journal:

Frontiers in Molecular Biosciences

Year:

2019

File:

PDF, 981 KB

2019

83

Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress

Xu, Linan, Nitika,, Hasin, Naushaba, Cuskelly, Daragh D., Wolfgeher, Donald, Doyle, Sean, Moynagh, Paul, Perrett, Sarah, Jones, Gary W., Truman, Andrew W.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 4.28 MB

english, 2019

84

Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains

Millson, Stefan H., Truman, Andrew W., Piper, Peter W.

Journal:

Year:

2003

File:

PDF, 750 KB

2003

85

Thioalbamide, A Thioamidated Peptide from Amycolatopsis alba, Affects Tumor Growth and Stemness by Inducing Metabolic Dysfunction and Oxidative Stress

Frattaruolo, Luca, Fiorillo, Marco, Brindisi, Matteo, Curcio, Rosita, Dolce, Vincenza, Lacret, Rodney, Truman, Andrew W., Sotgia, Federica, Lisanti, Michael P., Cappello, Anna Rita

Journal:

Year:

2019

Language:

english

File:

PDF, 4.40 MB

english, 2019

86

Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress

Xu, Linan, Nitika,, Hasin, Naushaba, Cuskelly, Daragh D., Wolfgeher, Donald, Doyle, Sean, Moynagh, Paul, Perrett, Sarah, Jones, Gary W., Truman, Andrew W.

Journal:

Scientific Reports

Year:

2019

File:

PDF, 4.28 MB

2019

87

Editorial overview: Antimicrobials: Tackling AMR in the 21st century

Hutchings, Matthew I, Truman, Andrew W, Wilkinson, Barrie

Journal:

Current Opinion in Microbiology

Year:

2019

File:

PDF, 337 KB

2019

88

Host expression system modulates recombinant Hsp70 activity through postâtranslational modifications

Rigo, Mauricio M., Borges, Thiago J., Lang, Benjamin J., Murshid, Ayesha, Nitika,, Wolfgeher, Donald, Calderwood, Stuart K., Truman, Andrew W., Bonorino, Cristina

Journal:

Year:

2020

File:

PDF, 3.11 MB

2020

89

Regulation of Bottromycin Biosynthesis Involves an Internal Transcriptional Start Site and a Cluster-Situated Modulator

Vior, Natalia M., Cea-Torrescassana, Eva, Eyles, Tom H., Chandra, Govind, Truman, Andrew W.

Journal:

Frontiers in Microbiology

Year:

2020

Language:

english

File:

PDF, 3.19 MB

english, 2020

90

The intracellular DNA sensors cGAS and IFI16 do not mediate effective antiviral immune responses to HSV-1 in human microglial cells

Jeffries, Austin M., Nitika,, Truman, Andrew W., Marriott, Ian

Journal:

Journal of NeuroVirology

Year:

2020

File:

PDF, 1.50 MB

2020

91

Genome mining strategies for ribosomally synthesised and post-translationally modified peptides

Russell, Alicia H., Truman, Andrew W.

Journal:

Computational and Structural Biotechnology Journal

Year:

2020

File:

PDF, 2.53 MB

2020

92

The bottromycin epimerase BotH defines a group of atypical Î±/Î²-hydrolase-fold enzymes

Sikandar, Asfandyar, Franz, Laura, Adam, Sebastian, Santos-Aberturas, Javier, Horbal, Liliya, Luzhetskyy, Andriy, Truman, Andrew W., Kalinina, Olga V., Koehnke, Jesko

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 7.70 MB

2020

93

Author Correction: The bottromycin epimerase BotH defines a group of atypical Î±/Î²-hydrolase-fold enzymes

Sikandar, Asfandyar, Franz, Laura, Adam, Sebastian, Santos-Aberturas, Javier, Horbal, Liliya, Luzhetskyy, Andriy, Truman, Andrew W., Kalinina, Olga V., Koehnke, Jesko

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 783 KB

2020

94

Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code

Nitika,, Porter, Corey M., Truman, Andrew W., Truttmann, Matthias C.

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 1.94 MB

2020

95

Acute toxicity of dihydroanatoxin-a from Microcoleus autumnalis in comparison to anatoxin-a

Puddick, Jonathan, van Ginkel, Roel, Page, Carrie D., Murray, J. Sam, Greenhough, Hannah E., Bowater, Joel, Selwood, Andrew I., Wood, Susanna A., Prinsep, MichÃ¨le R., Truman, Penelope, Munday, Rex, F

Journal:

Year:

2021

File:

PDF, 1.42 MB

2021

96

Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance

Nitika,, Blackman, Jacob S., Knighton, Laura E., Takakuwa, Jade E., Calderwood, Stuart K., Truman, Andrew W.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 4.33 MB

2020

97

H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2

Jain, Siddhant U., Rashoff, Andrew Q., Krabbenhoft, Samuel D., Hoelper, Dominik, Do, Truman J., Gibson, Tyler J., Lundgren, Stefan M., Bondra, Eliana R., Deshmukh, Shriya, Harutyunyan, Ashot S., Juret

Journal:

Year:

2020

File:

PDF, 4.17 MB

2020

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