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51

Minimising treatment-associated risks in systemic cancer therapy

Ulrich Jaehde, Andrea Liekweg, Sven Simons, Martina Westfeld

Journal:

International Journal of Clinical Pharmacy

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

52

Potential of on-line isotachophoresis-capillary zone electrophoresis with hydrodynamic counterflow in the analysis of various basic proteins and recombinant human interleukin-3

J. Bergmann, U. Jaehde, M. Mazereeuw, U.R. Tjaden, W. Schunack

Journal:

Journal of Chromatography A

Year:

1996

Language:

english

File:

PDF, 558 KB

english, 1996

53

Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

Cornelia B. Landersdorfer, Carl M. J. Kirkpatrick, Martina Kinzig, Jürgen B. Bulitta, Ulrike Holzgrabe, Ulrich Jaehde, Andreas Reiter, Kurt G. Naber, Michael Rodamer, Fritz Sörgel

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

54

Assessment of Activity Levels for CYP2D61, CYP2D62, and CYP2D6*41 Genes by Population Pharmacokinetics of Dextromethorphan

Abduljalil, K, Frank, D, Gaedigk, A, Klaassen, T, Tomalik-Scharte, D, Jetter, A, Jaehde, U, Kirchheiner, J, Fuhr, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 288 KB

english, 2010

55

Pharmacokinetic/Pharmacodynamic Modeling of Biomarker Response to Sunitinib in Healthy Volunteers

Lindauer, A, Di Gion, P, Kanefendt, F, Tomalik-Scharte, D, Kinzig, M, Rodamer, M, Dodos, F, Sörgel, F, Fuhr, U, Jaehde, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 331 KB

english, 2010

56

Individualised dosing strategy for high-dose carboplatin in patients with germ cell cancer

Kloft, C, Siegert, W, Jaehde, U

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

57

Pharmacokinetic and pharmacodynamic comparison of two doses of calcium folinate combined with continuous fluorouracil infusion in patients with advanced colorectal cancer

Sigrid Stremetzne, Walter Schunack, Ulrich Jaehde, Michael Streit, Ernst‐Dietrich Kreuser

Journal:

International Journal of Clinical Pharmacy

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

58

Development and Application of a Simple Assay to Quantify Cellular Adducts of Platinum Complexes with DNA

Charlotte Kloft, Christiane Eickhoff, Kai Schulze-Forster, H. Rainer Maurer, Walter Schunack, Ulrich Jaehde

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 709 KB

1999

59

Quantification and Visualization of the Transport of Octreotide, a Somatostatin Analogue, Across Monolayers of Cerebrovascular Endothelial Cells

Ulrich Jaehde, Rosalinde Masereeuw, Albertus G. De Boer, Gert Fricker, J. Fred Nagelkerke, J. Vonderscher, Douwe D. Breimer

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 2.09 MB

1994

60

In Vitroandin VivoTransport of Zidovudine (AZT) Across the Blood–Brain Barrier and the Effect of Transport Inhibitors

Rosalinde Masereeuw, Ulrich Jaehde, Mariska W. E. Langemeijer, Albertus G. de Boer, Douwe D. Breimer

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 1.31 MB

1994

61

Feasibility of intraventricular administration of etoposide in patients with metastatic brain tumours

Fleischhack, G, Reif, S, Hasan, C, Jaehde, U, Hettmer, S, Bode, U

Journal:

British Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 75 KB

english, 2001

62

Relationships between the chemical structure and the HPLC capacity factor of gyrase inhibitors and their metabolites in different methanol-water eluents

G. Gruber, U. Jaehde, F. Sörgel, R. Heiß, W. Schunack

Journal:

Analytical and Bioanalytical Chemistry

Year:

1988

Language:

english

File:

PDF, 203 KB

english, 1988

63

Effect of grapefruit juice intake on etoposide bioavailability

Reif, Stefanie, Nicolson, Marianne, Bisset, Donald, Reid, Muriel, Kloft, Charlotte, Jaehde, Ulrich, McLeod, Howard

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 200 KB

english, 2002

64

Effect of reactivity on cellular accumulation and cytotoxicity of oxaliplatin analogues

Buß, Irina, Kalayda, Ganna V., Lindauer, Andreas, Reithofer, Michael R., Galanski, Markus, Keppler, Bernhard K., Jaehde, Ulrich

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2012

Language:

english

File:

PDF, 300 KB

english, 2012

65

Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells

Jochen Zisowsky, Susanne Koegel, Stefan Leyers, Krishna Devarakonda, Matthias U. Kassack, Maja Osmak, Ulrich Jaehde

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 376 KB

english, 2007

66

Cellular accumulation and cytotoxicity of macromolecular platinum complexes in cisplatin-resistant tumor cells

Dirk Garmann, André Warnecke, Ganna V. Kalayda, Felix Kratz, Ulrich Jaehde

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 681 KB

english, 2008

67

Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

Ganna V Kalayda, Christina H Wagner, Irina Buß, Jan Reedijk, Ulrich Jaehde

Journal:

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

68

Brief report: Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration

Kurt G. Naber, Fritz Sörgel, Frieder Kees, Ulrich Jaehde, Harald Schumacher

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 378 KB

english, 1989

69

Brief report: Gastrointestinal secretion of ciprofloxacin: Evaluation of the charcoal model for investigations in healthy volunteers

Fritz Sörgel, Kurt G. Naber, Ulrich Jaehde, Andreas Reiter, Robert Seelmann, Gabriele Sigl

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 448 KB

english, 1989

70

Quantitative structure-pharmacokinetic relationships of gyrase inhibitors in man

U. Jaehde, F. Sörgel, R. Metz, G. Mahr, J. Zürcher, K.G. Naber, W. Schunack

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 207 KB

english, 1990

71

Synergistic interaction between cisplatin and gemcitabine in neuroblastoma cell lines and multicellular tumor spheroids

Odette G. Besançon, Godelieve A.M. Tytgat, Rutger Meinsma, René Leen, Jerry Hoebink, Ganna V. Kalayda, Ulrich Jaehde, Huib N. Caron, André B.P. van Kuilenburg

Journal:

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

72

Cisplatin Nephrotoxicity Is Critically Mediated via the Human Organic Cation Transporter 2

Giuliano Ciarimboli, Thomas Ludwig, Detlef Lang, Hermann Pavenstädt, Hermann Koepsell, Hans-Jürgen Piechota, Jörg Haier, Ulrich Jaehde, Jochen Zisowsky, Eberhard Schlatter

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

73

Quantification of interleukin-3 (rhil-3) and interleukin-6 (rhil-5) by capillary electrophoresis with isotachopghoretic sample preconcentration (ITP-CZE)

J. Bergman, U. Jaehde, W. Schunack

Journal:

European Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 150 KB

english, 1996

74

Metabolism of etoposide in patients undergoing high-dose chemotherapy

S. Stremetzne, U. Jaehde, R. Kaper, J. Beyer, W. Siegert, W. Schnunack

Journal:

European Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 54 KB

english, 1996

75

Considerable plasma levels of a cytotoxic etoposide metabolite in patients undergoing high-dose chemotherapy

S. Stremetzne, U. Jaehde, R. Kasper, J. Beyer, W. Siegert, W. Schunack

Journal:

European Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

76

Determination of soluble vascular endothelial growth factor receptor 3 (sVEGFR-3) in plasma as pharmacodynamic biomarker

Friederike Kanefendt, Andreas Lindauer, Klaus Mross, Uwe Fuhr, Ulrich Jaehde

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 331 KB

english, 2012

77

Arzneimitteltherapiesicherheit in Alten- und Pflegeheimen

Ulrich Jaehde, Petra A. Thürmann

Journal:

Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen

Year:

2012

Language:

german

File:

PDF, 338 KB

german, 2012

78

3058 POSTER Administration of reduced glutathione in FOLFOX4 regimen in advanced colorectal cancer: effect on oxaliplatin pharmacokinetics and on Pt-DNA adducts formation

M. Airoldi, P. Milla, L. Cattel, I. Gozzelino, A. Drescher, U. Jaehde, L. Branciforte, F. Pedani

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 59 KB

english, 2007

79

Plasma and Tissue Pharmacokinetics of Epirubicin and Paclitaxel in Patients Receiving Neoadjuvant Chemotherapy for Locally Advanced Primary Breast Cancer

Hunz, M, Jetter, A, Warm, M, Pantke, E, Tuscher, M, Hempel, G, Jaehde, U, Untch, M, Kurbacher, C, Fuhr, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 229 KB

english, 2007

80

Evaluation of a Pharmacology-Driven Dosing Algorithm of 3-Weekly Paclitaxel Using Therapeutic Drug Monitoring

Dr Markus Joerger, Stefanie Kraff, Alwin D. R. Huitema, Gary Feiss, Berta Moritz, Jan H. M. Schellens, Jos H. Beijnen, Ulrich Jaehde

Journal:

Clinical Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 233 KB

english, 2012

81

In vitro penetration of des-tyrosine1-D-phenylalanine3-β-casomorphin across the blood-brain barrier

Holger Stark, Joost B.M.M. Van Bree, Albertus G. De Boer, Ulrich Jaehde, Douwe D. Breimer

Journal:

Year:

1992

Language:

english

File:

PDF, 425 KB

english, 1992

82

Relevance of copper transporter 1 for cisplatin resistance in human ovarian carcinoma cells

Ganna V. Kalayda, Christina H. Wagner, Ulrich Jaehde

Journal:

Journal of Inorganic Biochemistry

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

83

PCN66 ADHERENCE IN CANCER PATIENTS RECEIVING ORAL CAPECITABINE

S Roth, S Simons, A Arjukese, M Braun, Y Ko, W Kuhn, U Mey, P Schwindt, H Wolter, U Jaehde

Journal:

Value in Health

Year:

2006

Language:

english

File:

PDF, 87 KB

english, 2006

84

PCN66 DEFINING HEALTH STATE UTILITIES FOR HAND-FOOT-SYNDROME

S Roth, S Simons, D Güney, N Reineking, ES Dietrich, U Jaehde

Journal:

Value in Health

Year:

2007

Language:

english

File:

PDF, 69 KB

english, 2007

85

PCN39 QUALITY ASSURANCE IN CANCER CHEMOTHERAPY THROUGH PHARMACEUTICAL CARE DOCUMENTATION

S Simons, SA Hudson, J Macintyre, M Maclean, U Jaehde

Journal:

Value in Health

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

86

PCN7 ANALYSIS AND CATEGORISATION OF DRUG-RELATED PROBLEMS ASSOCIATED WITH SYSTEMIC BREAST CANCER THERAPY

N Reineking, A Glasmacher, M Kühr, M Braun, W Kuhn, U Jaehde

Journal:

Value in Health

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

87

PCN16 ANALYSIS OF COSTS AND CONSEQUENCES IN CANCER PATIENTS RECEIVING CAPECITABINE

S Roth, S Lehmann, S Simons, ES Dietrich, Y Ko, W Kuhn, K Ruberg, P Schwindt, H Wolter, U Jaehde

Journal:

Value in Health

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008

88

310 Management of adverse drug events

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

89

Pharmacokinetics Following Intraventricular Administration of Chemotherapy in Patients with Neoplastic Meningitis

Dr Gudrun Fleischhack, Ulrich Jaehde, Udo Bode

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

90

Population Pharmacokinetics of the BEACOPP Polychemotherapy Regimen in Hodgkin’s Lymphoma and its Effect on Myelotoxicity

Stefan Wilde, Alexander Jetter, Stephan Rietbrock, Dirk Kasel, Andreas Engert, Andreas Josting, Beate Klimm, Georg Hempel, Stefanie Reif, Ulrich Jaehde, Ute Merkel, Dagmar Busse, Matthias Schwab, Volk

Journal:

Clinical Pharmacokinetics

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

91

Pharmacokinetic/Pharmacodynamic Modelling of Venlafaxine

Andreas Lindauer, Timo Siepmann, Reinhard Oertel, Angelika Jung, Tjalf Ziemssen, Ulrich Jaehde, Wilhelm Kirch, Martin Siepmann

Journal:

Clinical Pharmacokinetics

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

92

Pharmacokinetics and Pharmacodynamics of Single Rising Intravenous Doses (0.5mg–10mg) and Determination of Absolute Bioavailability of the Dipeptidyl Peptidase-4 Inhibitor Linagliptin (BI 1356) in Healthy Male Subjects

Silke Retlich, Vincent Duval, Arne Ring, Alexander Staab, Silke Hüttner, Arvid Jungnik, Ulrich Jaehde, Klaus A. Dugi, Dr Ulrike Graefe-Mody

Journal:

Clinical Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

93

Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors

Paola Di Gion, Friederike Kanefendt, Andreas Lindauer, Matthias Scheffler, Oxana Doroshyenko, Prof. Dr. med. Uwe Fuhr, Jürgen Wolf, Ulrich Jaehde

Journal:

Clinical Pharmacokinetics

Year:

2011

Language:

english

File:

PDF, 484 KB

english, 2011

94

Impact of Target-Mediated Drug Disposition on Linagliptin Pharmacokinetics and DPP-4 Inhibition in Type 2 Diabetic Patients

Retlich, Silke, Duval, Vincent, Graefe-Mody, Ulrike, Jaehde, Ulrich, Staab, Alexander

Journal:

Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 454 KB

english, 2010

95

Overcoming chemotherapy resistance of ovarian cancer cells by liposomal cisplatin: Molecular mechanisms unveiled by gene expression profiling

Koch, Martin, Krieger, Michaela L., Stölting, Daniel, Brenner, Norbert, Beier, Manfred, Jaehde, Ulrich, Wiese, Michael, Royer, Hans-Dieter, Bendas, Gerd

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 3.00 MB

english, 2013

96

Synthesis and Biological Activity of Water-Soluble Maleimide Derivatives of the Anticancer Drug Carboplatin Designed as Albumin-Binding Prodrugs

Warnecke, André, Fichtner, Iduna, Garmann, Dirk, Jaehde, Ulrich, Kratz, Felix

Journal:

Bioconjugate Chemistry

Year:

2004

Language:

english

File:

PDF, 236 KB

english, 2004

97

P163 clinical pharmacokinetics of high-dose carboplatin with special emphasis on protein binding

Kloft, C., Jaehde, U., Beyer, J., Steuer, J., Siegert, W., Schunack, W.

Journal:

European Journal of Pharmaceutical Sciences

Year:

1994

Language:

english

File:

PDF, 135 KB

english, 1994

98

P137 the use of capillary zone electrophoresis to monitor alterations in microheterogeneity of glycoproteins

Bergmann, J., Jaehde, U., Schunack, W.

Journal:

European Journal of Pharmaceutical Sciences

Year:

1994

Language:

english

File:

PDF, 115 KB

english, 1994

99

P162 clinical pharmacokinetics of etoposide during high-dose treatment in relation to toxicity

Stremetzne, S., Jaehde, U., Beyer, J., Steuer, J., Siegert, W., Schunack, W.

Journal:

European Journal of Pharmaceutical Sciences

Year:

1994

Language:

english

File:

PDF, 135 KB

english, 1994

100

Patientensicherheit verdient mehr Aufmerksamkeit

Jaehde, Ulrich, Müller, Hardy

Journal:

Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen

Year:

2014

Language:

german

File:

PDF, 408 KB

german, 2014