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1

International space station accomplishments update: Scientific discovery, advancing future exploration, and benefits brought home to earth

Thumm, Tracy, Robinson, Julie A., Alleyne, Camille, Hasbrook, Pete, Mayo, Susan, Buckley, Nicole, Johnson-Green, Perry, Karabadzhak, George, Kamigaichi, Shigeki, Umemura, Sayaka, Sorokin, Igor V., Zel

Journal:

Acta Astronautica

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

2

Complementary Role of Hypothermia Identification to the Quick Sequential Organ Failure Assessment Score in Predicting Patients With Sepsis at High Risk of Mortality: A Retrospective Analysis From a Multicenter, Observational Study

Kushimoto, Shigeki, Gando, Satoshi, Ogura, Hiroshi, Umemura, Yutaka, Saitoh, Daizoh, Mayumi, Toshihiko, Fujishima, Seitaro, Abe, Toshikazu, Shiraishi, Atsushi, Ikeda, Hiroto, Kotani, Joji, Miki, Yasuo

Journal:

Journal of Intensive Care Medicine

Year:

2018

Language:

english

File:

PDF, 300 KB

english, 2018

3

Diagnosis of sepsis‐induced disseminated intravascular coagulation and coagulopathy

Iba, Toshiaki, Umemura, Yutaka, Watanabe, Eizo, Wada, Takeshi, Hayashida, Kei, Kushimoto, Shigeki

Journal:

Acute Medicine & Surgery

Year:

2019

Language:

english

File:

PDF, 253 KB

english, 2019

4

Clinical factors affecting acquired resistance to gefitinib in previously treated Japanese patients with advanced nonsmall cell lung cancer

Yoshihiko Segawa, Katsuyuki Hotta, Shigeki Umemura, Yoshiro Fujiwara, Tetsu Shinkai, Hiroshi Ueoka, Nagio Takigawa, Masahiro Tabata, Katsuyuki Kiura, Mitsune Tanimoto

Journal:

Year:

2006

Language:

english

File:

PDF, 115 KB

english, 2006

5

Numerical study of Marangoni convection effect on the melting of GaSb/InSb/GaSb

Yasunori Okano, Shigeki Umemura, Yoichi Enomoto, Yasuhiro Hayakawa, Masashi Kumagawa, Akira Hirata, Sadik Dost

Journal:

Journal of Crystal Growth

Year:

2002

Language:

english

File:

PDF, 159 KB

english, 2002

6

Regulated growth of diatom cells on self-assembled monolayers

Kazuo Umemura, Tomoaki Yamada, Yuta Maeda, Koichi Kobayashi, Reiko Kuroda, Shigeki Mayama

Journal:

Journal of Nanobiotechnology

Year:

2007

Language:

english

File:

PDF, 3.66 MB

english, 2007

7

Cultivation of Melosira nummuloides cells in the presence of platinum: Preparation of metal-containing frustules

Taku Yamazaki, Hiroshi Sasanuma, Shigeki Mayama, Kazuo Umemura

Journal:

physica status solidi (c)

Year:

2010

Language:

english

File:

PDF, 353 KB

english, 2010

8

An analysis of the physiological FDG uptake in the stomach with the water gastric distention method

Kiyohisa Kamimura, Seigo Fujita, Ryuichi Nishii, Hideyuki Wakamatsu, Shigeki Nagamachi, Tatsuhiko Yano, Mikio Ogita, Yoshiro Umemura, Toshiro Fujimoto, Masayuki Nakajo

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

9

A phase I study of 3-day topotecan and cisplatin in elderly patients with small-cell lung cancer

Keiichi Fujiwara, Hiroshi Ueoka, Katsuyuki Kiura, Masahiro Tabata, Nagio Takigawa, Katsuyuki Hotta, Shigeki Umemura, Keisuke Sugimoto, Takuo Shibayama, Haruhito Kamei, Shingo Harita, Niro Okimoto, Mit

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 198 KB

english, 2006

10

Serum level of arginine-vasopressin influences the prognosis of extensive-disease small-cell lung cancer

Shigeki Umemura, Yoshihiko Segawa, Hiroshi Ueoka, Katsuyuki Hotta, Katsuyuki Kiura, Nagio Takigawa, Masahiro Tabata, Akihiro Bessho, Tetsu Shinkai, Mitsune Tanimoto

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 380 KB

english, 2007

11

Interstitial lung disease associated with gemcitabine treatment in patients with non-small-cell lung cancer and pancreatic cancer

Shigeki Umemura, Hiromichi Yamane, Toshimitsu Suwaki, Tsutomu Katoh, Takuya Yano, Yasuhiro Shiote, Nagio Takigawa, Katsuyuki Kiura, Haruhito Kamei

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 1.58 MB

english, 2011

12

Diatom Cells Grown and Baked on a Functionalized Mica Surface

Kazuo Umemura, Yusuke Noguchi, Takuya Ichinose, Yo Hirose, Reiko Kuroda, Shigeki Mayama

Journal:

Journal of Biological Physics

Year:

2008

Language:

english

File:

PDF, 708 KB

english, 2008

13

Associations between liver18F fluoro-2-deoxy-d-glucose accumulation and various clinical parameters in a Japanese population: influence of the metabolic syndrome

Kiyohisa Kamimura, Shigeki Nagamachi, Hideyuki Wakamatsu, Ryutaro Higashi, Mikio Ogita, Shin-ichiro Ueno, Seigo Fujita, Yoshiro Umemura, Toshiro Fujimoto, Masayuki Nakajo

Journal:

Annals of Nuclear Medicine

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

14

Cavitary pulmonary involvement of diffuse large B-cell lymphoma transformed from extra nodal marginal zone B-cell lymphoma MALT type

Hiromichi Yamane, Masahiro Ohsawa, Yasuhiro Shiote, Shigeki Umemura, Toshimitsu Suwaki, Atsuko Shirakawa, Haruhito Kamei, Nagio Takigawa, Katsuyuki Kiura

Journal:

Clinical Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 541 KB

english, 2011

15

Humidity dependence of microwear characteristics of amorphous carbon films on silicon substrates

Shigeki Tsuchitani, Yasuyuki Sogawa, Reizo Kaneko, Shigeru Hirono, Shigeru Umemura

Journal:

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

16

Importance of observation interval in two-dimensional video analysis of individual diatom cells

Murase, Ayumu, Kubota, Yosuke, Hori, Shunichiro, Hirayama, Shigeyuki, Mayama, Shigeki, Umemura, Kazuo

Journal:

European Biophysics Journal

Year:

2012

Language:

english

File:

PDF, 372 KB

english, 2012

17

Modification of glucocorticoid sensitivity by MAP kinase signaling pathways in glucocorticoid-induced T-cell apoptosis

Tomoko Tanaka, Taijiro Okabe, Shigeki Gondo, Mitsue Fukuda, Masahiro Yamamoto, Tsukuru Umemura, Kenzaburo Tani, Masatoshi Nomura, Kiminobu Goto, Toshihiko Yanase, Hajime Nawata

Journal:

Experimental Hematology

Year:

2006

Language:

english

File:

PDF, 1.02 MB

english, 2006

18

Aberrant DNA methylation profile in pleural fluid for differential diagnosis of malignant pleural mesothelioma

Masanori Fujii, Nobukazu Fujimoto, Akio Hiraki, Kenichi Gemba, Keisuke Aoe, Shigeki Umemura, Hideki Katayama, Nagio Takigawa, Katsuyuki Kiura, Mitsune Tanimoto, Takumi Kishimoto

Journal:

Year:

2012

Language:

english

File:

PDF, 301 KB

english, 2012

19

Two-dimensional trajectory analysis of the diatom Navicula sp. using a micro chamber

Ayumu Murase, Yosuke Kubota, Shigeyuki Hirayama, Yoshikazu Kumashiro, Teruo Okano, Shigeki Mayama, Kazuo Umemura

Journal:

Journal of Microbiological Methods

Year:

2011

Language:

english

File:

PDF, 493 KB

english, 2011

20

Clinical outcome in patients with leptomeningeal metastasis from non-small cell lung cancer: Okayama Lung Cancer Study Group

Umemura, Shigeki, Tsubouchi, Kazuya, Yoshioka, Hiroshige, Hotta, Katsuyuki, Takigawa, Nagio, Fujiwara, Keiichi, Horita, Naokatsu, Segawa, Yoshihiko, Hamada, Noboru, Takata, Ichiro, Yamane, Hiromichi,

Journal:

Year:

2012

Language:

english

File:

PDF, 379 KB

english, 2012

21

Ab initio molecular orbital study on the formic acid dimer

Hayashi, Soichi, Umemura, Junzo, Kato, Shigeki, Morokuma, Keiji

Journal:

Journal of Physical Chemistry

Year:

1984

Language:

english

File:

PDF, 623 KB

english, 1984

22

Semi-circular microgrooves to observe active movements of individual Navicula pavillardii cells

Umemura, Kazuo, Haneda, Takahiro, Tanabe, Masashi, Suzuki, Akira, Kumashiro, Yoshikazu, Itoga, Kazuyoshi, Okano, Teruo, Mayama, Shigeki

Journal:

Journal of Microbiological Methods

Year:

2013

Language:

english

File:

PDF, 783 KB

english, 2013

23

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung

Takahashi, Akiko, Ishii, Genichiro, Kinoshita, Tomonari, Yoshida, Tatsuya, Umemura, Shigeki, Hishida, Tomoyuki, Yoh, Kiyotaka, Niho, Seiji, Goto, Koichi, Ohmatsu, Hironobu, Ohe, Yuichiro, Nagai, Kanji

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 472 KB

english, 2013

24

Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma

Yoshida, Tatsuya, Ishii, Genichiro, Goto, Koichi, Yoh, Kiyotaka, Niho, Seiji, Umemura, Shigeki, Matsumoto, Shingo, Ohmatsu, Hironobu, Nagai, Kanji, Ohe, Yuichiro, Ochiai, Atsushi

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

25

Safety and efficacy of gefitinib treatment in elderly patients with non-small-cell lung cancer: Okayama Lung Cancer Study Group Experience

Hotta, Katsuyuki, Ueoka, Hiroshi, Kiura, Katsuyuki, Tabata, Masahiro, Ogino, Atsuko, Umemura, Shigeki, Harita, Shingo, Gemba, Kenichi, Yonei, Toshiro, Bessho, Akihiro, Maeda, Tadashi, Tanimoto, Mitsun

Journal:

Acta Oncologica

Year:

2005

Language:

english

File:

PDF, 68 KB

english, 2005

26

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: Identification of prognostic microenvironmental factors after chemoradiation

Zenke, Yoshitaka, Ishii, Genichiro, Ohe, Yuichiro, Kaseda, Kaoru, Yoshida, Tatsuya, Matsumoto, Shingo, Umemura, Shigeki, Yoh, Kiyotaka, Niho, Seiji, Goto, Koichi, Ohmatsu, Hironobu, Kuwata, Takeshi, N

Journal:

Pathology International

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

27

Use of a microchamber for analysis of thermal variation of the gliding phenomenon of singleNavicula pavillardiicells

Umemura, Kazuo, Miyabayashi, Toru, Taira, Hisao, Suzuki, Akira, Kumashiro, Yoshikazu, Okano, Teruo, Mayama, Shigeki

Journal:

European Biophysics Journal

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

28

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung

Udagawa, Hibiki, Ishii, Genichiro, Morise, Masahiro, Umemura, Shigeki, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Tsuboi, Masahiro, Goto, Koichi, Ochiai, Atsushi, Ohe, Yuichiro

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

29

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy

Koriyama, Haruki, Ishii, Genichiro, Yoh, Kiyotaka, Neri, Shinya, Morise, Masahiro, Umemura, Shigeki, Matsumoto, Shingo, Niho, Seiji, Ohmatsu, Hironobu, Tsuboi, Masahiro, Goto, Koichi, Ochiai, Atsushi

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 755 KB

english, 2015

30

Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis

Umemura, Shigeki, Mimaki, Sachiyo, Makinoshima, Hideki, Tada, Satoshi, Ishii, Genichiro, Ohmatsu, Hironobu, Niho, Seiji, Yoh, Kiyotaka, Matsumoto, Shingo, Takahashi, Akiko, Morise, Masahiro, Nakamura,

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 481 KB

english, 2014

31

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia

Watanabe, Naohiro, Niho, Seiji, Kirita, Keisuke, Umemura, Shigeki, Matsumoto, Shingo, Yoh, Kiyotaka, Ohmatsu, Hironobu, Goto, Koichi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 442 KB

english, 2015

32

Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma

Matsumura, Yuki, Umemura, Shigeki, Ishii, Genichiro, Tsuta, Koji, Matsumoto, Shingo, Aokage, Keiju, Hishida, Tomoyuki, Yoshida, Junji, Ohe, Yuichiro, Suzuki, Hiroyuki, Ochiai, Atsushi, Goto, Koichi, N

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

33

Single cell analysis using a glass microchamber for studying movement fluctuations of Navicula pavillardii and Seminavis robusta diatom cells

Umemura, Kazuo, Sadoya, Yusuke, Nagao, Kazuki, Oikawa, Ryota, Hanada, Yasutaka, Sugioka, Koji, Mayama, Shigeki

Journal:

Year:

2015

Language:

english

File:

PDF, 537 KB

english, 2015

34

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor ( EGFR )-mutated Lung Adenocarcinoma

Makinoshima, Hideki, Takita, Masahiro, Saruwatari, Koichi, Umemura, Shigeki, Obata, Yuuki, Ishii, Genichiro, Matsumoto, Shingo, Sugiyama, Eri, Ochiai, Atsushi, Abe, Ryo, Goto, Koichi, Esumi, Hiroyasu,

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

35

Management of leptomeningeal metastasis in patients with lung cancer

Umemura, Shigeki

Journal:

Lung Cancer Management

Year:

2013

File:

PDF, 1.30 MB

2013

36

Management of leptomeningeal metastasis in patients with lung cancer

Umemura, Shigeki

Journal:

Lung Cancer Management

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

37

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma

Hisakane, Kakeru, Saruwatari, Koichi, Fujii, Satoshi, Kirita, Keisuke, Umemura, Shigeki, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Kuwata, Takeshi, Ochiai, Atsushi, Gemma, Akih

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2016

Language:

english

File:

PDF, 1.54 MB

english, 2016

38

Impact of single nucleotide polymorphisms on severe hepatotoxicity induced by EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring EGFR mutations

Sugiyama, Eri, Umemura, Shigeki, Nomura, Shogo, Kirita, Keisuke, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Tsuboi, Masahiro, Ohe, Yuichiro, Goto, Koichi

Journal:

Year:

2015

Language:

english

File:

PDF, 365 KB

english, 2015

39

RECIST progression patterns during EGFR tyrosine kinase inhibitor treatment of advanced non-small cell lung cancer patients harboring an EGFR mutation

Yoshida, Tatsuya, Yoh, Kiyotaka, Niho, Seiji, Umemura, Shigeki, Matsumoto, Shingo, Ohmatsu, Hironobu, Ohe, Yuichiro, Goto, Koichi

Journal:

Year:

2015

Language:

english

File:

PDF, 854 KB

english, 2015

40

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations

Saruwatari, Koichi, Ikemura, Shinnosuke, Sekihara, Keigo, Kuwata, Takeshi, Fujii, Satoshi, Umemura, Shigeki, Kirita, Keisuke, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Ochiai,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

41

Morphology and Physical-Chemical Properties of Baked Nanoporous Frustules

Umemura, Kazuo, Noguchi, Yusuke, Ichinose, Takuya, Hirose, Yo, Mayama, Shigeki

Journal:

Journal of Nanoscience and Nanotechnology

Year:

2010

Language:

english

File:

PDF, 2.21 MB

english, 2010

42

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring EGFR Mutations

Zenke, Yoshitaka, Yoh, Kiyotaka, Matsumoto, Shingo, Umemura, Shigeki, Niho, Seiji, Ohmatsu, Hironobu, Goto, Koichi, Ohe, Yuichiro

Journal:

Clinical Lung Cancer

Year:

2016

Language:

english

File:

PDF, 389 KB

english, 2016

43

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma

Matsuzawa, Reiko, Kirita, Keisuke, Kuwata, Takeshi, Umemura, Shigeki, Matsumoto, Shingo, Fujii, Satoshi, Yoh, Kiyotaka, Kojima, Motohiro, Niho, Seiji, Ohmatsu, Hironobu, Ochiai, Atsushi, Tsuboi, Masah

Journal:

Year:

2016

Language:

english

File:

PDF, 1.87 MB

english, 2016

44

Acute and Progressive Tracheal Stenosis after Proton Beam Therapy with Concurrent Chemotherapy for Non–Small Cell Lung Cancer

Zenke, Yoshitaka, Umemura, Shigeki, Motegi, Atsushi, Furukawa, Kinya, Kirita, Keisuke, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Tsuboi, Masahiro, Akimoto, Tetsuo, Goto, Koichi

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 852 KB

english, 2016

45

P3-1-23A retrospective analysis of tolerability in EGFR-mutated NSCLC patients who received afatinib

Koriyama, Haruki, Yoh, Kiyotaka, Kirita, Keisuke, Umemura, Shigeki, Matsumoto, Shingo, Niho, Seiji, Ohmatsu, Hironobu, Goto, Koichi

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 29 KB

english, 2015

46

O1-10-4Clinicopathological analysis between exon 19 deletion and L858R in EGFR-mutant completely resected lung adenocarcinoma

Matsuzawa, Reiko, Yoh, Kiyotaka, Ishii, Genichiro, Kirita, Keisuke, Umemura, Shigeki, Matsumoto, Shingo, Niho, Seiji, Ohmatsu, Hironobu, Tsuboi, Masahiro, Goto, Koichi

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

47

Controlled Nanoporous Structures of a Marine Diatom

Umemura, Kazuo, Liao, Xing, Mayama, Shigeki, Gad, Mohammed

Journal:

Journal of Nanoscience and Nanotechnology

Year:

2007

Language:

english

File:

PDF, 4.18 MB

english, 2007

48

Remarkable shrinkage of sarcomatoid renal cell carcinoma with single-agent gemcitabine

Fujiwara, Yoshiro, Kiura, Katsuyuki, Tabata, Masahiro, Takigawa, Nagio, Hotta, Katsuyuki, Umemura, Shigeki, Omori, Masako, Gemba, Kenichi, Ueoka, Hiroshi, Tanimoto, Mitsune

Journal:

Anti-Cancer Drugs

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

49

Role of gastric distention with additional water in differentiating locally advanced gastric carcinomas from physiological uptake in the stomach on 18F-fluoro-2-deoxy-D-glucose PET

Kamimura, Kiyohisa, Nagamachi, Shigeki, Wakamatsu, Hideyuki, Fujita, Seigo, Nishii, Ryuichi, Umemura, Yoshiro, Ogita, Mikio, Komada, Naoto, Sakurai, Toshinori, Inoue, Teruhiko, Fujimoto, Toshiro, Naka

Journal:

Nuclear Medicine Communications

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

50

Synchronous double primary lung cancers with different response to pemetrexed

Umemura, Shigeki, Yamane, Hiromichi, Yano, Takuya, Hoshika, Toshiko, Shiote, Yasuhiro, Takigawa, Nagio, Suwaki, Toshimitsu, Shirakawa, Atsuko, Kamei, Haruhito

Journal:

Anti-Cancer Drugs

Year:

2011

Language:

english

File:

PDF, 995 KB

english, 2011