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1

Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome

Hamlett, Eric D., Goetzl, Edward J., Ledreux, Aurélie, Vasilevko, Vitaly, Boger, Heather A., LaRosa, Angela, Clark, David, Carroll, Steven L., Carmona Iragui, Maria, Fortea, Juan, Mufson, Elliott J.,

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 725 KB

english, 2016

2

Generation and characterization of the humoral immune response to DNA immunization with a chimeric β-amyloid-interleukin-4 minigene

Anahit Ghochikyan, Vitaly Vasilevko, Irina Petrushina, Nina Movsesyan, Davit Babikyan, Wenqiang Tian, Nadya Sadzikava, Ted M. Ross, Elizabeth Head, David H. Cribbs, Michael G. Agadjanyan

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 287 KB

english, 2003

3

Mixed Cerebrovascular Disease and the Future of Stroke Prevention

Fisher, Mark, Vasilevko, Vitaly, Cribbs, David H.

Journal:

Translational Stroke Research

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

4

Mimotopes of conformational epitopes in fibrillar β-amyloid

Goar Gevorkian, Irina Petrushina, Karen Manoutcharian, Anahit Ghochikyan, Gonzalo Acero, Vitaly Vasilevko, David H. Cribbs, Michael G. Agadjanyan

Journal:

Journal of Neuroimmunology

Year:

2004

Language:

english

File:

PDF, 635 KB

english, 2004

5

Immunodominant epitope and properties of pyroglutamate-modified Aβ-specific antibodies produced in rabbits

G. Acero, K. Manoutcharian, V. Vasilevko, M.E. Munguia, T. Govezensky, G. Coronas, A. Luz-Madrigal, D.H. Cribbs, G. Gevorkian

Journal:

Journal of Neuroimmunology

Year:

2009

Language:

english

File:

PDF, 981 KB

english, 2009

6

Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody libraries

M. Medecigo, K. Manoutcharian, V. Vasilevko, T. Govezensky, M.E. Munguia, B. Becerril, A. Luz-Madrigal, L. Vaca, D.H. Cribbs, G. Gevorkian

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 702 KB

english, 2010

7

Anti-11[E]-pyroglutamate-modified amyloid β antibodies cross-react with other pathological Aβ species: Relevance for immunotherapy

Roxanna Perez-Garmendia, Vanessa Ibarra-Bracamontes, Vitaly Vasilevko, Jose Luna-Muñoz, Raul Mena, Tzipe Govezensky, Gonzalo Acero, Karen Manoutcharian, David H. Cribbs, Goar Gevorkian

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

8

Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta

Vitaly Vasilevko, Viorela Pop, Hyun Jin Kim, Tommy Saing, Charles C. Glabe, Saskia Milton, Edward G. Barrett, Carl W. Cotman, David H. Cribbs, Elizabeth Head

Journal:

Neurobiology of Disease

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

9

Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42

R.S. Solórzano-Vargas, V. Vasilevko, G. Acero, K.E. Ugen, R. Martinez, T. Govezensky, R. Vazquez-Ramirez, C. Kubli-Garfias, D.H. Cribbs, K. Manoutcharian, G. Gevorkian

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 550 KB

english, 2008

10

Novel approaches for immunotherapeutic intervention in Alzheimer's disease

Vitaly Vasilevko, David H. Cribbs

Journal:

Neurochemistry International

Year:

2006

Language:

english

File:

PDF, 531 KB

english, 2006

11

An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease

Kwang-Mook Jung, Giuseppe Astarita, Sevil Yasar, Vitaly Vasilevko, David H. Cribbs, Elizabeth Head, Carl W. Cotman, Daniele Piomelli

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.86 MB

english, 2012

12

Immunization with fibrillar Aβ1–42 in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Aβ

Elizabeth Head, Edward G. Barrett, M. Paul Murphy, Pritam Das, Mihaela Nistor, Floyd Sarsoza, Charles C. Glabe, Rakez Kayed, Saskia Milton, Vitaly Vasilevko, Norton W. Milgram, Michael G. Agadjanyan,

Journal:

Year:

2006

Language:

english

File:

PDF, 519 KB

english, 2006

13

Importance of IgG2c isotype in the immune response to β-amyloid in amyloid precursor protein/transgenic mice

Irina Petrushina, Mike Tran, Nadya Sadzikava, Anahit Ghochikyan, Vitaly Vasilevko, Michael G. Agadjanyan, David H. Cribbs

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

14

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal -Catenin Pathway Function in an Alzheimer's Disease Model

Kitazawa, M., Cheng, D., Tsukamoto, M. R., Koike, M. A., Wes, P. D., Vasilevko, V., Cribbs, D. H., LaFerla, F. M.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.64 MB

english, 2011

15

O1-06-04: Reduction of both soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

Salvatore Oddo, Antonella Caccamo, Vitaly Vasilevko, David H. Cribbs, Frank M. LaFerla

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

16

P-185: Environmental factors and their impact on Alzheimer’s like pathology in older APP/Tg mice

Vitaly Vasilevko, Hyun Jin Kim, Christopher K. Tran, Rodmehr Ajdari, David H. Cribbs

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 50 KB

english, 2007

17

O2-02-06: Blocking Aβ42 accumulation delays the onset and progression of Tau pathology and cognitive decline via CHIP: A mechanistic link between Aβ and Tau pathology

Salvatore Oddo, Antonella Caccamo, Bert Tseng, David Cheng, Vitaly Vasilevko, David H. Cribbs, Frank M. LaFerla

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

18

Blocking interleukin-1 function attenuates Alzheimer's pathology via reducing anti-inflammatory responses in a transgenic mouse model

Masashi Kitazawa, David Cheng, Michelle Tsukamoto, Vitaly Vasilevko, David C. Cribbs, Frank M. LaFerla

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

19

18F-fluoropropyl curcumin binding to β-amyloid plaques in transgenic mouse model of Alzheimer's disease

Pooja C. Patel, F. Sarsoza, V. Vasilevko, M.-L. Pan, W. Tsu, C. Constantinescu, R. Coleman, E. Head, J. Mukherjee

Journal:

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

20

Evaluation of 18F-FBM for imaging β-amyloid plaques and neurofibrillary tangles

Crystal S. Wang, E. Head, W. Tsu, A. Doshi, V. Vasilevko, R. Coleman, C. Constantinescu, N. Saigal, M.-L. Pan, J. Mukherjee

Journal:

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

21

Mannan-Abeta28conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Irina Petrushina, Anahit Ghochikyan, Mikayel Mkrtichyan, Grigor Mamikonyan, Nina Movsesyan, Rodmehr Ajdari, Vitaly Vasilevko, Adrine Karapetyan, Andrew Lees, Michael G Agadjanyan, David H Cribbs

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 1.75 MB

english, 2008

22

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss

Cohen, R. M., Rezai-Zadeh, K., Weitz, T. M., Rentsendorj, A., Gate, D., Spivak, I., Bholat, Y., Vasilevko, V., Glabe, C. G., Breunig, J. J., Rakic, P., Davtyan, H., Agadjanyan, M. G., Kepe, V., Barrio

Journal:

Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 5.75 MB

english, 2013

23

The Bradykinin B1 Receptor Regulates Aβ Deposition and Neuroinflammation in Tg-SwDI Mice

Passos, Giselle F., Medeiros, Rodrigo, Cheng, David, Vasilevko, Vitaly, LaFerla, Frank M., Cribbs, David H.

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

24

A β -Immunotherapy for Alzheimer's Disease Using Mannan–Amyloid-Beta Peptide Immunoconjugates

Ghochikyan, Anahit, Petrushina, Irina, Lees, Andrew, Vasilevko, Vitaly, Movsesyan, Nina, Karapetyan, Adrine, Agadjanyan, Michael G., Cribbs, David H.

Journal:

DNA and Cell Biology

Year:

2006

Language:

english

File:

PDF, 766 KB

english, 2006

25

P4-385 Alzheimer's epitope vaccine based on the dominant B cell epitope of Aβ and padre, a foreign T cell epitope

Agadjanyan, Michael G., Petrushina, Irina, Ghochikyan, Anahit, Vasilevko, Vitaly, Movsesyan, Nina, Oddo, Salvatore, LaFerla, Frank M., Cribbs, David H.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

26

P4-327

Cribbs, David, Vasilevko, Vitaly, Xu, Feng, Previti, Mary Lou, Van Nostrand, William E.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

27

p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

Walls, Ken C., Ager, Rahasson R., Vasilevko, Vitaly, Cheng, Dave, Medeiros, Rodrigo, LaFerla, Frank M.

Journal:

Neuroscience Letters

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

28

Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy

Vasilevko, Vitaly, Passos, Giselle F., Quiring, Daniel, Head, Elizabeth, Kim, Richard C., Fisher, Mark, Cribbs, David H.

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 404 KB

english, 2010

29

CD80 (B7-1) and CD86 (B7-2) are Functionally Equivalent in the Initiation and Maintenance of CD4 + T-Cell Proliferation after Activation with Suboptimal Doses of PHA

Vasilevko, Vitaly, Ghochikyan, Anahit, Holterman, Mark J., Agadjanyan, Michael G.

Journal:

DNA and Cell Biology

Year:

2002

Language:

english

File:

PDF, 369 KB

english, 2002

30

Comparative Analysis of H&E and Prussian Blue Staining in a Mouse Model of Cerebral Microbleeds

Liu, S., Grigoryan, M. M., Vasilevko, V., Sumbria, R. K., Paganini-Hill, A., Cribbs, D. H., Fisher, M. J.

Journal:

Journal of Histochemistry & Cytochemistry

Year:

2014

Language:

english

File:

PDF, 830 KB

english, 2014

31

Blocking A 42 Accumulation Delays the Onset and Progression of Tau Pathology via the C Terminus of Heat Shock Protein70-Interacting Protein: A Mechanistic Link between A and Tau Pathology

Oddo, S., Caccamo, A., Tseng, B., Cheng, D., Vasilevko, V., Cribbs, D. H., LaFerla, F. M.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

32

A Two-Year Study with Fibrillar -Amyloid (A ) Immunization in Aged Canines: Effects on Cognitive Function and Brain A

Head, E., Pop, V., Vasilevko, V., Hill, M., Saing, T., Sarsoza, F., Nistor, M., Christie, L.-A., Milton, S., Glabe, C., Barrett, E., Cribbs, D.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 372 KB

english, 2008

33

Experimental Investigation of Antibody-Mediated Clearance Mechanisms of Amyloid- in CNS of Tg-SwDI Transgenic Mice

Vasilevko, V., Xu, F., Previti, M. L., Van Nostrand, W. E., Cribbs, D. H.

Journal:

Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

34

Prototype Alzheimer's Disease Vaccine Using the Immunodominant B Cell Epitope from -Amyloid and Promiscuous T Cell Epitope Pan HLA DR-Binding Peptide

Agadjanyan, M. G., Ghochikyan, A., Petrushina, I., Vasilevko, V., Movsesyan, N., Mkrtichyan, M., Saing, T., Cribbs, D. H.

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

35

Immunization with Amyloid- Attenuates Inclusion Body Myositis-Like Myopathology and Motor Impairment in a Transgenic Mouse Model

Kitazawa, M., Vasilevko, V., Cribbs, D. H., LaFerla, F. M.

Journal:

Journal of Neuroscience

Year:

2009

Language:

english

File:

PDF, 510 KB

english, 2009

36

Reduction of Soluble Abeta and Tau, but Not Soluble Abeta Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles

Oddo, S., Vasilevko, V., Caccamo, A., Kitazawa, M., Cribbs, D. H., LaFerla, F. M.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.28 MB

english, 2006

37

Experimental hypertension increases spontaneous intracerebral hemorrhages in a mouse model of cerebral amyloidosis

Passos, Giselle F, Kilday, Kelley, Gillen, Daniel L, Cribbs, David H, Vasilevko, Vitaly

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 466 KB

english, 2015

38

Therapeutic Modulation of Cerebral Microhemorrhage in a Mouse Model of Cerebral Amyloid Angiopathy

Fisher, M., Vasilevko, V., Passos, G. F., Ventura, C., Quiring, D., Cribbs, D. H.

Journal:

Year:

2011

Language:

english

File:

PDF, 589 KB

english, 2011

39

Visualization of microbleeds with optical histology in mouse model of cerebral amyloid angiopathy

Lo, Patrick, Crouzet, Christian, Vasilevko, Vitaly, Choi, Bernard

Journal:

Microvascular Research

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

40

Corrigendum to “Visualization of microbleeds with optical histology in mouse model of cerebral amyloid angiopathy” [105, May 2016, 109–113]

Lo, Patrick, Crouzet, Christian, Vasilevko, Vitaly, Choi, Bernard

Journal:

Microvascular Research

Year:

2016

Language:

english

File:

PDF, 121 KB

english, 2016

41

Immunotherapy in a Natural Model of Aβ Pathogenesis: The Aging Beagle

Vasilevko, Vitaly, Head, Elizabeth

Journal:

CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets - CNS & Neurological Disorders)

Year:

2009

Language:

english

File:

PDF, 161 KB

english, 2009

42

SPIE Proceedings [SPIE SPIE BiOS - San Francisco, California, United States (Saturday 13 February 2016)] Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation - Visualization of microhemorrhages with optical histology in mouse model of cerebral amyloid angiopathy (Conference Presentation)

Madsen, Steen J., Yang, Victor X. D., Jansen, E. Duco, Luo, Qingming, Mohanty, Samarendra K., Thakor, Nitish V., Lo, Patrick, Crouzet, Christian, Vasilevko, Vitaly, Choi, Bernard

Year:

2016

Language:

english

File:

PDF, 112 KB

english, 2016

43

Nutritional Supplement (NT Factor™) Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects

Agadjanyan, Michael, Vasilevko, Vitaley, Ghochikyan, Anahit, Berns, Paul, Kesslak, Patrick, Settineri, Robert A., Nicolson, Garth L.

Journal:

Journal of Chronic Fatigue Syndrome

Year:

2003

Language:

english

File:

PDF, 889 KB

english, 2003

44

A murine model of inflammation-induced cerebral microbleeds

Sumbria, Rachita K., Grigoryan, Mher Mahoney, Vasilevko, Vitaly, Krasieva, Tatiana B., Scadeng, Miriam, Dvornikova, Alexandra K., Paganini-Hill, Annlia, Kim, Ronald, Cribbs, David H., Fisher, Mark J.

Journal:

Journal of Neuroinflammation

Year:

2016

Language:

english

File:

PDF, 2.88 MB

english, 2016

45

Blood-brain barrier penetrating biologic TNF-α inhibitor for Alzheimer's disease

Chang, Rudy, Knox, Jillian, Chang, Jae, Derbedrossian, Aram, Vasilevko, Vitaly, Cribbs, David, Boado, Ruben J., Pardridge, William M., Sumbria, Rachita

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

46

Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

Rachita K. Sumbria,Vitaly Vasilevko…

Journal:

Journal of Neuroinflammation

Year:

2017

Language:

english

File:

PDF, 3.74 MB

english, 2017

47

PROTECTIVE EFFECTS OF A BRAIN-PENETRATING BIOLOGIC TNF-ALPHA INHIBITOR IN A MOUSE MODEL OF ALZHEIMER’S DISEASE

Chang, Rudy, Knox, Jillian, Chang, Jae, Woods, Jeffery, Derbedrossian, Aram, Vasilevko, Vitaly, Cribbs, David H., Boado, Ruben, Pardridge, William M., Sumbria, Rachita

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 160 KB

english, 2017

48

Aging exacerbates development of cerebral microbleeds in a mouse model

Sumbria, Rachita K., Grigoryan, Mher Mahoney, Vasilevko, Vitaly, Paganini-Hill, Annlia, Kilday, Kelley, Kim, Ronald, Cribbs, David H., Fisher, Mark J.

Journal:

Journal of Neuroinflammation

Year:

2018

Language:

english

File:

PDF, 1.29 MB

english, 2018

49

Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease

Astarita, Giuseppe, Jung, Kwang-Mook, Vasilevko, Vitaly, DiPatrizio, Nicholas V., Martin, Sarah K., Cribbs, David H., Head, Elizabeth, Cotman, Carl W., Piomelli, Daniele, Gaetani, Silvana

Journal:

Year:

2011

Language:

english

File:

PDF, 548 KB

english, 2011

50

Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits

Gold, Eric M., Vasilevko, Vitaly, Hasselmann, Jonathan, Tiefenthaler, Casey, Hoa, Danny, Ranawaka, Kasuni, Cribbs, David H., Cummings, Brian J.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.75 MB

english, 2018