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51

Spatially resolved and quantitative analysis of VISTA/PD-1H as a novel immunotherapy target in human non-small cell lung cancer

Villarroel-Espindola, Franz, Yu, Xiaoqing, Datar, Ila, Mani, Nikita, Sanmamed, Miguel F., Velcheti, Vamsidhar, Syrigos, Konstantinos N, Toki, Maria I, Zhao, Hongyu, Chen, Lieping, Herbst, Roy S., Scha

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 4.91 MB

english, 2017

52

OA 12.07 LOXO-292, a Potent, Highly Selective RET Inhibitor, in MKI-Resistant RET Fusion-Positive Lung Cancer Patients with and without Brain Metastases

Velcheti, V., Bauer, T., Subbiah, V., Cabanillas, M., Lakhani, N., Wirth, L., Oxnard, G., Shah, M., Sherman, E., Smith, S., Eary, T., Cruickshank, S., Tuch, B., Ebata, K., Nguyen, M., Corsi-Travali, S

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 335 KB

english, 2017

53

PUB082 Radiomic Features on Baseline CT Are Predictive of Recurrence in Early Stage Non-Small Cell Lung Cancer Patients

Vaidya, P., Patil, P., Choi, H., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 478 KB

english, 2017

54

P1.02-001 SLFN11 Expression in Early Stage Non-Small Cell Lung Cancer Predicts Benefit from Adjuvant Chemotherapy with Taxane and Platinum

Velcheti, V., Schwartz, S., Cecchi, F., Tian, Y., Sellappan, S., Rudin, C., Poirier, J., Hembrough, T.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 669 KB

english, 2017

55

OA 13.02 Distribution of PD-L1 Tumor Expression by Assay Type in Patients with Metastatic NSCLC (MNSCLC)

Velcheti, V., Cao, X., Liu, F., Patwardhan, P.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 454 KB

english, 2017

56

MA 17.11 Prediction of Response to Trimodality Therapy Using CT-Derived Radiomic Features in Stage III Non-Small Cell Lung Cancer (NSCLC)

Jain, P., Ahmad, U., Murthy, S., Stephans, K., Khorrami, M., Madabhushi, A., Velcheti, V.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 298 KB

english, 2017

57

MA 13.03 Quantitative Spatial Profiling of PD-1/PD-L1 Interaction Predicts Response to Adjuvant Chemotherapy Non–Small-Cell Lung Cancer

Velcheti, V., Bordeaux, J., Dakappagari, N., Pennell, N., Stevenson, J., Khunger, M., Kim, J., Schalper, K., Rimm, D.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 347 KB

english, 2017

58

MA 15.06 ERBB Receptor Feedback Inhibitor-1 Alterations in Non-Small Cell Lung Cancer

Schneider, J., Jain, P., Schalper, K., Lovly, C., Gardner, F., Ross, J., Schrock, A., Ali, S., Miller, V., Velcheti, V.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 238 KB

english, 2017

59

Safety and efficacy of PD-1/PD-L1 inhibitors in treatment naïve and chemotherapy refractory patients with Non-small cell lung cancer: a systematic review and meta-analysis

Khunger, Monica, Jain, Prantesh, Rakshit, Sagar, Pasupuleti, Vinay, Hernandez, Adrian V., Stevenson, James, Pennell, Nathan A., Velcheti, Vamsidhar

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

60

Efficacy of Vinorelbine in the Second-Line Setting and Beyond in Non-small Cell Lung Cancer

Subramanian, Janakiraman, Velcheti, Vamsidhar, Baggstrom, Maria Q., Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 33 KB

english, 2007

61

Role of immune-checkpoint inhibitors in lung cancer

Jain, Prantesh, Jain, Chhavi, Velcheti, Vamsidhar

Journal:

Therapeutic Advances in Respiratory Disease

Year:

2018

Language:

english

File:

PDF, 154 KB

english, 2018

62

Absence of Mutations in the Epidermal Growth Factor Receptor (EGFR) Kinase Domain in Patients with Mesothelioma

Velcheti, Vamsidhar, Kasai, Yumi, Viswanathan, Avinash K., Ritter, Jon, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 88 KB

english, 2009

63

Biomarkers for immune-related toxicities of checkpoint inhibitors: current progress and the road ahead

Patil, Pradnya D., Burotto, Mauricio, Velcheti, Vamsidhar

Journal:

Expert Review of Molecular Diagnostics

Year:

2018

Language:

english

File:

PDF, 2.13 MB

english, 2018

64

CLINICAL UTILITY OF ROUTINELY ADDING POSITRON EMISSION TOMOGRAPHY (PET) TO COMPUTER TOMOGRAPHY (CT) AND ENDOSCOPIC ULTRASOUND (EUS) IN THE INITIAL STAGING OF ESOPHAGEAL CARCINOMA: THE WASHINGTON UNIVERSITY IN ST. LOUIS EXPERIENCE

Velcheti, Vamsidhar, Viswanathan, Avinash K., Badhey, Neeraj, Gao, Feng, Peifer, Kevin, Edmundowicz, Steven, Early, Dayna, Govindan, Ramaswamy, Azar, Riad

Journal:

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

65

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

Wrangle, John M, Velcheti, Vamsidhar, Patel, Manish R, Garrett-Mayer, Elizabeth, Hill, Elizabeth G, Ravenel, James G, Miller, Jeffrey S, Farhad, Mohammad, Anderton, Kate, Lindsey, Kathryn, Taffaro-Nes

Journal:

The Lancet Oncology

Year:

2018

Language:

english

File:

PDF, 357 KB

english, 2018

66

Radiation-Induced Myonecrosis Presenting as a Subcutaneous Mass After Combined Modality Therapy for Non-small Cell Lung Cancer

Velcheti, Vamsidhar, Gilstrap, Eve, Bradley, Jeffrey, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 530 KB

english, 2007

67

Selective RET Kinase Inhibition for Patients with RET-Altered Cancers

Subbiah, V, Velcheti, V, Tuch, B B, Ebata, K, Busaidy, N L, Cabanillas, M E, Wirth, L J, Stock, S, Smith, S, Lauriault, V, Corsi-Travali, S, Henry, D, Burkard, M, Hamor, R, Bouhana, K, Winski, S, Wall

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

68

Novel pharmacologic approach to enhance the epigenetic and immune priming effect of decitabine in patients with advanced non-small cell lung cancer

Velcheti, Vamsidhar, Pennell, Nathan A, Rakshit, Sagar, Stevenson, James, Shapiro, Marc, Almeida, Francisco A, Gurajala, Ram, Schalper, Kurt, Saunthararajah, Yogen

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 603 KB

english, 2015

69

Clinical significance of PD-L1 protein expression on tumor-associated macrophages in lung cancer

Schalper, Kurt, Carvajal-Hausdorf, Daniel, McLaughlin, Joseph, Velcheti, Vamsidhar, Chen, Lieping, Sanmamed, Miguel, Herbst, Roy S, Rimm, David L

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 212 KB

english, 2015

70

Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer

Carvajal-Hausdorf, Daniel E., Mani, Nikita, Velcheti, Vamsidhar, Schalper, Kurt A., Rimm, David L.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2017

Language:

english

File:

PDF, 1.98 MB

english, 2017

71

A case of crizotinib-induced esophageal ulcers

Sussman, Tamara A, Khunger, Monica, Velcheti, Vamsidhar

Journal:

Lung Cancer Management

Year:

2017

Language:

english

File:

PDF, 3.08 MB

english, 2017

72

High SOX2 Levels Predict Better Outcome in Non-Small Cell Lung Carcinomas

Velcheti, Vamsidhar, Schalper, Kurt, Yao, Xiaopan, Cheng, Huan, Kocoglu, Mehmet, Dhodapkar, Kavita, Deng, Yanhong, Gettinger, Scott, Rimm, David L., Chellappan, Srikumar P.

Journal:

Year:

2013

Language:

english

File:

PDF, 981 KB

english, 2013

73

WAC/RET: A Novel RET Oncogenic Fusion Variant in Non–Small Cell Lung Carcinoma

Velcheti, Vamsidhar, Madison, Russell, Ali, Siraj M., Schrock, Alexa B.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 164 KB

english, 2018

74

“Spin the Wheel to Spindle”: A Rare Case of Inflammatory Myofibroblastic Tumor

Panchabhai, Tanmay, Bandyopadhyay, Debabrata, Raja, Siva, Murthy, Sudhish, Velcheti, Vamsidhar, Mukhopadhyay, Sanjay, Cicenia, Joseph, Sethi, Sonali

Journal:

Year:

2014

Language:

english

File:

PDF, 17 KB

english, 2014

75

Phase I Trial of ALT-803, a Novel Recombinant Interleukin-15 Complex, in Patients with Advanced Solid Tumors

Margolin, Kim, Morishima, Chihiro, Velcheti, Vamsidhar, Miller, Jeffrey S, Lee, Sylvia M., Silk, Ann W., Holtan, Shernan G, Lacroix, Andreanne M., Fling, Steven P, Kaiser, Judith C, Egan, Jack O, Jone

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

76

Programmed death-1/programmed death-1 ligand axis as a therapeutic target in oncology: current insights

Velcheti, Vamsidhar, Schalper, Kurt, Venur, Vyshak

Journal:

Journal of Receptor Ligand and Channel Research

Year:

2014

File:

PDF, 884 KB

2014

77

Programmed death-1/programmed death-1 ligand axis as a therapeutic target in oncology: current insights

Velcheti, Vamsidhar, Schalper, Kurt, Venur, Vyshak

Journal:

Journal of Receptor Ligand and Channel Research

Year:

2014

Language:

english

File:

PDF, 884 KB

english, 2014

78

Spatial architecture and arrangement of tumor-infiltrating lymphocytes for predicting likelihood of recurrence in early-stage non-small cell lung cancer

Corredor, Germán, Wang, Xiangxue, Zhou, Yu, Lu, Cheng, Fu, Pingfu, Syrigos, Konstantinos N, Rimm, David L., Yang, Michael, Romero, Eduardo, Schalper, Kurt A., Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 827 KB

english, 2018

79

Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET–Rearranged Lung Cancers

Drilon, Alexander, Lin, Jessica J., Filleron, Thomas, Ni, Ai, Milia, Julie, Bergagnini, Isabella, Hatzoglou, Vaios, Velcheti, Vamsidhar, Offin, Michael, Li, Bob, Carbone, David P., Besse, Benjamin, Mo

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 585 KB

english, 2018

80

15PDIn patients with advanced non-small cell lung cancer (NSCLC) LAG-3 is expressed on activated TILs and predicts resistance to PD-1 axis blockers

Datar, I, Sanmamed, M F, Choi, J, Wang, J, Henick, B S, Badri, T, Mejias, L D, Lozano, M, Gracia, J L, Velcheti, V, Herbst, R, Melero, I, Chen, L, Schalper, K A

Journal:

Annals of Oncology

Year:

2017

Language:

english

File:

PDF, 76 KB

english, 2017

81

Response

Khunger, Monica, Hernandez, Adrian V., Velcheti, Vamsidhar

Journal:

Year:

2018

Language:

english

File:

PDF, 124 KB

english, 2018

82

P1-035: Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: Washington University experience

Subramanian, Janakiraman, Velcheti, Vamsidhar, Goodgame, Boone, Gao, Feng, Baggstrom, Maria, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

83

Quantitative vessel tortuosity: A potential CT imaging biomarker for distinguishing lung granulomas from adenocarcinomas

Alilou, Mehdi, Orooji, Mahdi, Beig, Niha, Prasanna, Prateek, Rajiah, Prabhakar, Donatelli, Christopher, Velcheti, Vamsidhar, Rakshit, Sagar, Yang, Michael, Jacono, Frank, Gilkeson, Robert, Linden, Phi

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.25 MB

english, 2018

84

Post-treatment changes in hematological parameters predict response to nivolumab monotherapy in non-small cell lung cancer patients

Khunger, Monica, Patil, Pradnya Dinkar, Khunger, Arjun, Li, Manshi, Hu, Bo, Rakshit, Sagar, Basu, Arnab, Pennell, Nathan, Stevenson, James P., Elson, Paul, Panchabhai, Tanmay S., Velcheti, Vamsidhar,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

85

P1.13-34 Changes in Radiomic Features Between Baseline and Two Weeks Post-Nivolumab Treatment Are Predictive of Pathologic Complete Response

Khorrami, M., Prasanna, P., Corredor-Prada, G., Velcheti, V., Madabhushi, A., Bera, K.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 290 KB

english, 2018

86

P3.16-10 Radiomic Features on CT are Prognostic of Recurrence as well as Predictive of Added Benefit of Adjuvant Chemotherapy in ES-NSCLC

Vaidya, P., Bera, K., Fu, P., Ganesan, S., Khunger, A., Patil, P., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 424 KB

english, 2018

87

Cases from the irAE Tumor Board: A Multidisciplinary Approach to a Patient Treated with Immune Checkpoint Blockade Who Presented with a New Rash

Patil, Pradnya D., Fernandez, Anthony P., Velcheti, Vamsidhar, Tarhini, Ahmad, Funchain, Pauline, Rini, Brian, Khasawneh, Mohamad, Pennell, Nathan A.

Journal:

Year:

2018

Language:

english

File:

PDF, 525 KB

english, 2018

88

OA12.07 Clinical Activity of LOXO-292, a Highly Selective RET Inhibitor, in Patients with RET Fusion+ Non-Small Cell Lung Cancer

Oxnard, G., Subbiah, V., Park, K., Bauer, T., Wirth, L., Velcheti, V., Shah, M., Besse, B., Boni, V., Reckamp, K., Loong, H., Bazhenova, L., Solomon, B., Tan, D., Patel, J., Johnson, M., Gazzah, A., M

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 210 KB

english, 2018

89

LBA55Primary efficacy results from B-F1RST, a prospective phase II trial evaluating blood-based tumour mutational burden (bTMB) as a predictive biomarker for atezolizumab (atezo) in 1L non-small cell lung cancer (NSCLC)

Kim, E S, Velcheti, V, Mekhail, T, Leal, T A, Dowell, J E, Tsai, M L, Dakhil, C S R, Stella, P, Shen, V, Hu, S, Paul, S M, Shames, D S, Schleifman, E, Fabrizio, D A, Yun, C, Phan, S, Socinski, M A

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 84 KB

english, 2018

90

Real-world PD-L1 testing and distribution of PD-L1 tumor expression by immunohistochemistry assay type among patients with metastatic non-small cell lung cancer in the United States

Velcheti, Vamsidhar, Patwardhan, Pallavi D., Liu, Frank Xiaoqing, Chen, Xin, Cao, Xiting, Burke, Thomas, Ahmad, Aamir

Journal:

Year:

2018

Language:

english

File:

PDF, 721 KB

english, 2018

91

105PDetection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292

Besse, B, Subbiah, V, Drilon, A, Shah, M, Wirth, L J, Bauer, T M, Velcheti, V, Lakhani, N, Boni, V, Solomon, B J, Johnson, M, Park, K, Patel, J, Cabanillas, M E, Sherman, E, Zhu, E, Gordon, K, Ebata,

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

92

P1.01-83 IMpower150: Impact of Chemotherapy Cycles in 1L Metastatic NSCLC in Patients Treated With Atezolizumab + Bevacizumab

Rothenstein, J., Spira, A., Velcheti, V., Natale, R., Kozloff, M., Kosty, M., Goldschmidt, J., Mazieres, J., Ponce Aix, S., Yu, W., Gandhi, M., Lee, A., Shankar, G., Lin, W., Thomas, C.

Journal:

Journal of Thoracic Oncology

Year:

2018

File:

PDF, 230 KB

2018

93

Expression and clinical significance of PD-L1, B7-H3, B7-H4 and TILs in human small cell lung Cancer (SCLC)

Carvajal-Hausdorf, Daniel, Altan, Mehmet, Velcheti, Vamsidhar, Gettinger, Scott N., Herbst, Roy S., Rimm, David L., Schalper, Kurt A.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2019

Language:

english

File:

PDF, 1.58 MB

english, 2019

94

Combination of Peri- and Intratumoral Radiomic Features on Baseline CT Scans Predicts Response to Chemotherapy in Lung Adenocarcinoma

Khorrami, Mohammadhadi, Khunger, Monica, Zagouras, Alexia, Patil, Pradnya, Thawani, Rajat, Bera, Kaustav, Rajiah, Prabhakar, Fu, Pingfu, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Radiology: Artificial Intelligence

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

95

51OFirst-line pembrolizumab monotherapy in metastatic PD-L1 positive non-small cell lung cancer: A real-world analysis of time on treatment in US community oncology practices

Velcheti, V, Chandwani, S, Chen, X, Pietanza, M C, Burke, T

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

96

Novel Quantitative Imaging for Predicting Response to Therapy: Techniques and Clinical Applications

Bera, Kaustav, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

American Society of Clinical Oncology Educational Book

Year:

2018

Language:

english

File:

PDF, 968 KB

english, 2018

97

Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis.

Datar, Ila J, Sanmamed, Miguel F, Wang, Jun, Henick, Brian S, Choi, Jungmin, Badri, Ti, Dong, Weilai, Mani, Nikita, Toki, Maria I, Mejías, Luis, Lozano, Maria D., Perez-Gracia, Jose Luis, Velcheti, Va

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 3.85 MB

english, 2019

98

Programmed Cell Death 1 (PD-1) Ligand (PD-L1) Expression in Solid Tumors As a Predictive Biomarker of Benefit From PD-1/PD-L1 Axis Inhibitors: A Systematic Review and Meta-Analysis

Khunger, Monica, Hernandez, Adrian V., Pasupuleti, Vinay, Rakshit, Sagar, Pennell, Nathan A., Stevenson, James, Mukhopadhyay, Sanjay, Schalper, Kurt, Velcheti, Vamsidhar

Journal:

JCO Precision Oncology

Year:

2017

File:

PDF, 910 KB

2017

99

BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations

Sheikine, Yuri, Pavlick, Dean, Klempner, Samuel J., Trabucco, Sally E., Chung, Jon H., Rosenzweig, Mark, Wang, Kai, Velcheti, Vamsidhar, Frampton, Garrett M., Peled, Nir, Murray, Molly, Chae, Young Kw

Journal:

JCO Precision Oncology

Year:

2018

Language:

english

File:

PDF, 658 KB

english, 2018

100

Higher-Level Pathway Objectives of Epigenetic Therapy: A Solution to the p53 Problem in Cancer

Velcheti, Vamsidhar, Radivoyevitch, Tomas, Saunthararajah, Yogen

Journal:

American Society of Clinical Oncology Educational Book

Year:

2017

Language:

english

File:

PDF, 1.79 MB

english, 2017