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51

D-Isomeric replacements within the 6–9 core sequence of ac-[Nle4]-α-MSH4–11-NH2: A topological model for the solution conformation of α-melanotropin

Elizabeth E. Sugg, Wayne L. Cody, Zalfa Abdel-Malek, Mac E. Hadley, Victor J. Hruby

Journal:

Year:

1986

Language:

english

File:

PDF, 809 KB

english, 1986

52

1H-nmr assignments and conformational studies of melanin concentrating hormone in water using two-dimensional nmr

Terry O. Matsunaga, Catherine A. Gehrig, Victor J. Hruby

Journal:

Year:

1990

Language:

english

File:

PDF, 407 KB

english, 1990

53

Topographical requirements for δ-selective opioid peptides

Gregory V. Nikiforovich, Victor J. Hruby, Om Prakash, Catherine A. Gehrig

Journal:

Year:

1991

Language:

english

File:

PDF, 1.00 MB

english, 1991

54

Conformational and topographical considerations in the design of biologically active peptides

Victor J. Hruby

Journal:

Year:

1993

Language:

english

File:

PDF, 833 KB

english, 1993

55

Prediction of the conformational requirements for binding to the κ-opioid receptor and its subtypes. I. Novel α-helical cyclic peptides and their role in receptor selectivity

Nathan Collins, Victor J. Hruby

Journal:

Year:

1994

Language:

english

File:

PDF, 897 KB

english, 1994

56

Characterization of linear and cyclic glucagon analogs by fast atom bombardment mass spectrometry

Nevena N. Mollova, Karl H. Schram, Ying Lin, Ramalinga Dharanipragada, Victor J. Hruby

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1993

Language:

english

File:

PDF, 767 KB

english, 1993

57

ChemInform Abstract: De Novo Design, Synthesis, and Biological Activities of High-Affinity and Selective Non-Peptide Agonists of the δ-Opioid Receptor.

Victor J. Hruby, ET AL. ET AL.

Journal:

Year:

1999

File:

PDF, 30 KB

1999

58

ChemInform Abstract: Asymmetric Michael Addition Reactions of Chiral Ni(II)-Complex of Glycine with (N-trans-Enoyl)oxazolidines: Improved Reactivity and Stereochemical Outcome.

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby

Journal:

Year:

2000

File:

PDF, 33 KB

2000

59

ChemInform Abstract: First Stereoselective Synthesis of an Optically Pure β-Substituted Histidine: (2S,3S)-β-Methylhistidine.

Sihe Wang, Xuejun Tang, Victor J. Hruby

Journal:

Year:

2000

File:

PDF, 32 KB

2000

60

ChemInform Abstract: Enkephalin-Based Drug Design: Conformational Analysis of O-Linked Glycopeptides by NMR and Molecular Modeling.

Caroline T. Kriss, Bih-Show Lou, Lajos Z. Szabo, Scott A. Mitchell, Victor J. Hruby, Robin Polt

Journal:

Year:

2000

File:

PDF, 31 KB

2000

61

ChemInform Abstract: (S)- or (R)-3-(E-Enoyl)-4-phenyl-1,3-oxazolidin-2-ones: Ideal Michael Acceptors to Afford a Virtually Complete Control of Simple and Face Diastereoselectivity in Addition Reactions with Glycine Derivatives.

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby

Journal:

Year:

2000

File:

PDF, 33 KB

2000

62

ChemInform Abstract: An Asymmetric Synthesis Protocol to Prepare Topographically Constrained β-Substituted Aromatic Amino Acids

Subo Liao, Victor J. Hruby

Journal:

Year:

2000

File:

PDF, 27 KB

2000

63

ChemInform Abstract: A Practical Asymmetric Synthesis of Enantiomerically Pure 3-Substituted Pyroglutamic Acids and Related Compounds.

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby

Journal:

Year:

2000

File:

PDF, 33 KB

2000

64

ChemInform Abstract: Stereochemically Defined C-Substituted Glutamic Acids and Their Derivatives. Part 7. Rational Design of Highly Diastereoselective, Organic Base-Catalyzed, Room-Temperature Michael Addition Reactions.

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby, Luc Van Meervelt, Takashi Yamazaki

Journal:

Year:

2001

Language:

english

File:

PDF, 40 KB

english, 2001

65

ChemInform Abstract: Stereoselective Synthesis of Conformationally Constrained Reverse Turn Dipeptide Mimetics

Wei Qiu, Xuyuan Gu, Vadim A. Soloshonok, Michael D. Carducci, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 30 KB

2001

66

ChemInform Abstract: Asymmetric Synthesis of α,β-Dialkyl-α-phenylalanines via Direct Alkylation of a Chiral Alanine Derivative with Racemic α-Alkylbenzyl Bromides. A Case of High Enantiomer Differentiation at Room Temperature.

Vadim A. Soloshonok, Xuejun Tang, Victor J. Hruby, Luc Van Meervelt

Journal:

Year:

2001

Language:

english

File:

PDF, 37 KB

english, 2001

67

ChemInform Abstract: Practical and Efficient Synthesis of Orthogonally Protected Constrained 4-Guanidinoprolines.

Makoto Tamaki, Guoxia Han, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 31 KB

2001

68

Design in Topographical Space of Peptide and Peptidomimetic Ligands that Affect Behavior. A Chemist′s Glimpse at the Mind—Body Problem

Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 25 KB

2001

69

ChemInform Abstract: An Efficient Approach to Asymmetric Synthesis of Dipeptide β-Turn Mimetics: Indolizidinone Amino Acids.

Wei Wang, Chiyi Xiong, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 31 KB

2001

70

ChemInform Abstract: Synthesis of 4-cis-Phenyl-L-proline via Hydrogenolysis.

Makoto Tamaki, Guoxia Han, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 28 KB

2001

71

ChemInform Abstract: A Study of Conjugate Addition to a γ,δ-Dioxolanyl-α,β-unsaturated Ester.

Guoxia Han, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 32 KB

2001

72

ChemInform Abstract: Synthesis of (2S,3S)-β-Methyltryptophan.

Guoxia Han, Arwel Lewis, Victor J. Hruby

Journal:

Year:

2001

File:

PDF, 31 KB

2001

73

ChemInform Abstract: Practical, Asymmetric Synthesis of Aromatic-Substituted Bulky and Hydrophobic Tryptophan Derivatives.

Wei Wang, Chiyi Xiong, Jianqing Yang, Victor J. Hruby

Journal:

Year:

2002

File:

PDF, 33 KB

2002

74

ChemInform Abstract: An Efficient Synthesis of (2S,6S)- and meso-Diaminopimelic Acids via Asymmetric Hydrogenation.

Wei Wang, Chiyi Xiong, Jianqing Yang, Victor J. Hruby

Journal:

Year:

2002

File:

PDF, 32 KB

2002

75

ChemInform Abstract: Design of Peptide Agonists

Victor J. Hruby, Richard S. Agnes, Chaozhong Cai

Journal:

Year:

2002

File:

PDF, 23 KB

2002

76

ChemInform Abstract: Design and Synthesis of Hydrophobic, Bulky χ2-Constrained Phenylalanine and Naphthylalanine Derivatives.

Wei Wang, Junyi Zhang, Chiyi Xiong, Victor J. Hruby

Journal:

Year:

2002

File:

PDF, 36 KB

2002

77

ChemInform Abstract: Design of Nonpeptides from Peptide Ligands for Peptide Receptors

Victor J. Hruby, Wei Qiu, Toru Okayama, Vadim A. Soloshonok

Journal:

Year:

2002

File:

PDF, 24 KB

2002

78

ChemInform Abstract: Practical, Asymmetric Synthesis of Aromatic-Substituted Bulky and Hydrophobic Tryptophan and Phenylalanine Derivatives.

Wei Wang, Chiyi Xiong, Junyi Zhang, Victor J. Hruby

Journal:

Year:

2002

Language:

english

File:

PDF, 36 KB

english, 2002

79

A General Asymmetric Synthesis of syn- and anti-β-Substituted Cysteine and Serine Derivatives.

Chiyi Xiong, Wei Wang, Victor J. Hruby

Journal:

Year:

2002

File:

PDF, 33 KB

2002

80

Applications of Synthetic Peptides

Victor J. Hruby, Terry O. Matsunaga

Journal:

Year:

2002

File:

PDF, 24 KB

2002

81

Design and Synthesis of Novel χ2-Constrained Phenylalanine, Naphthylalanine, and Tryptophan Analogues and Their Use in Biologically Active Melanotropin Peptides.

Wei Wang, Minying Cai, Chiyi Xiong, Junyi Zhang, Dev Trivedi, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 254 KB

2003

82

A Convenient, Room-Temperature — Organic Base Protocol for Preparing Chiral 3-(Enoyl)-1,3-oxazolidin-2-ones.

Vadim A. Soloshonok, Hisanori Ueki, Changchun Jiang, Chaozhong Cai, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 123 KB

2003

83

An Efficient Method for Large-Scale Synthesis of Stereochemically Defined and Conformationally Constrained β-Substituted or α,β-Disubstituted Amino Acids

Xuejun Tang, Vadim A. Soloshonok, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 61 KB

2003

84

The Novel Asymmetric Synthesis of β-Functionalized Phenylalanine Derivatives

Chiyi Xiong, Wei Wang, Chaozhong Cai, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 60 KB

2003

85

The General Asymmetric Synthesis of syn- and anti-β-Substituted Cysteine and Serine Derivatives

Chiyi Xiong, Wei Wang, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 60 KB

2003

86

Efficient and Stereoselective Synthesis of Novel cis-4-Substituted Proline Analogues.

Junyi Zhang, Wei Wang, Chiyi Xiong, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 141 KB

2003

87

Two Novel and Efficient Approaches to Synthesis of Enantiopure Dipeptide β-Turn Mimetics: Indolizidinone Amino Acids

Wei Wang, Chiyi Xiong, Jiangqian Yang, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 67 KB

2003

88

Stereoselective Synthesis of Individual Isomers of Leu-enkephalin Analogues Containing Substituted β-Turn Bicyclic Dipeptide Mimetics.

Chiyi Xiong, Junyi Zhang, Peg Davis, Wei Wang, Jinfa Ying, Frank Porreca, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 140 KB

2003

89

Peptide Science: Exploring the Use of Chemical Principles and Interdisciplinary Collaboration for Understanding Life Processes

Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 50 KB

2003

90

Stereoselective Synthesis of Novel Dipeptide β-Turn Mimetics Targeting Melanocortin Peptide Receptors.

Junyi Zhang, Chiyi Xiong, Jinfa Ying, Wei Wang, Victor J. Hruby

Journal:

Year:

2003

File:

PDF, 81 KB

2003

91

Intelligent Design in Combinatorial Chemistry: Use of Designed Peptide Libraries to Explore Secondary and Tertiary Structures in Peptides and Proteins

Scott M. Cowell, Xuyuan Gu, Josef Vagner, Victor J. Hruby

Journal:

Year:

2005

File:

PDF, 59 KB

2005

92

ChemInform Abstract: Organic Chemistry and Biology: Chemical Biology Through the Eyes of Collaboration

Victor J. Hruby

Journal:

Year:

2010

File:

PDF, 15 KB

2010

93

ChemInform Abstract: Novel anti-β-Functionalized γ,δ-Unsaturated Amino Acids via a Thio-Claisen Rearrangement.

Zhihua Liu, Hongchang Qu, Xuyuan Gu, Kwang-Soo Lee, Bryan Grossman, Vlad K. Kumirov, Victor J. Hruby

Journal:

Year:

2010

File:

PDF, 27 KB

2010

94

ChemInform Abstract: New Perspective in Peptide Chemistry by N-Alkylation

Horst Kessler, Jayanta Chatterjee, Lucas Doedens, Florian Operrer, Eric Biron, Daniel Hoyer, Herbert Schmid, Chaim Gilon, Victor J. Hruby, Dale F. Mierke

Journal:

Year:

2011

File:

PDF, 18 KB

2011

95

ChemInform Abstract: Improved Synthesis of D,L-Fluorocitric Acid.

Ruben Vardanyan, Vlad K. Kumirov, Victor J. Hruby

Journal:

Year:

2012

File:

PDF, 34 KB

2012

96

Melanin concentrating hormone (MCH) effects on teleost (Chrysiptera cyanea) melanophores

Noriko Oshima, Hiroaki Kasukawa, Ryozo Fujii, Brian C. Wilkes, Victor J. Hruby, Ana Maria de L. Castrucci, Mac E. Hadley

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1985

Language:

english

File:

PDF, 453 KB

english, 1985

97

Synthesis of S-benzyl-DL-[1-13C]cysteine and its incorporation into oxytocin and [8-arginlne]vasopressin and related compounds by total synthesis. Separation of diastekeoisomers by partition chromatography and HPLC

Victor J. Hruby, V. Viswanatha, Young C. S. Yang

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1980

Language:

english

File:

PDF, 501 KB

english, 1980

98

Synthesis and biological evaluation of the superagonist [Nα-chlorotriazinylaminofluorescein-Ser1, Nle4, D-Phe7]-α-MSH

Dhirendra N. Chaturvedi, Victor J. Hruby, Ana Maria de L. Castrucci, Kristie L. Kreutzfeld, Mac E. Hadley

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 523 KB

english, 1985

99

Chemistry and biochemistry of the amino acids. Edited by G. C. Barrett. Chapman and Hall Ltd., New York, NY 10001. 1985. 684pp. 16 × 24.5 cm. ISBN 0 412234106. $99.00

Victor J. Hruby

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 147 KB

english, 1986

100

Synthesis and actions of a melanotropin conjugate, Ac-[Nle4, Glu(gamma-4′-hydroxyanilide)5, D-Phe7]α-MSH4–10-NH2, on melanocytes and melanoma cells in vitro

Fahad Al-Obeidi, Marybeth Mulcahy, Valerie S. Pitt, Velma Begay, Mac E. Hadley, Victor J. Hruby

Journal:

Journal of Pharmaceutical Sciences

Year:

1990

Language:

english

File:

PDF, 695 KB

english, 1990