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1

Nrf2, the Master Regulator of Anti-Oxidative Responses

Vomund, Sandra, Schäfer, Anne, Parnham, Michael, Brüne, Bernhard, von Knethen, Andreas

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 3.36 MB

english, 2017

2

Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells

Trümper, Verena, von Knethen, Andreas, Preuß, Annegret, Ermilov, Eugeny, Hackbarth, Steffen, Kuchler, Laura, Gunne, Sandra, Schäfer, Anne, Bornhütter, Tobias, Vereb, György, Ujlaky-Nagy, Lázló, Brüne,

Journal:

Year:

2019

File:

PDF, 2.18 MB

2019

3

Nitric oxide, oxidative stress, and apoptosis

Brune, Bernhard, Zhou, Jie, Von Knethen, Andreas

Journal:

Kidney International

Year:

2003

Language:

english

File:

PDF, 96 KB

english, 2003

4

Peroxisome proliferator-activated receptor γ (PPARγ) and sepsis

Andreas von Knethen, Mathias Soller, Bernhard Brüne

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2007

Language:

english

File:

PDF, 223 KB

english, 2007

5

Apoptotic cell-derived factors induce arginase II expression in murine macrophages by activating ERK5/CREB

Vera Barra, Anne-Marie Kuhn, Andreas von Knethen, Andreas Weigert, Bernhard Brüne

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

6

Nitric oxide (NO): an effector of apoptosis

Brüne, Bernhard, von Knethen, Andreas, Sandau, Katrin B

Journal:

Cell Death & Differentiation

Year:

1999

Language:

english

File:

PDF, 227 KB

english, 1999

7

Etoposide and cisplatin induced apoptosis in activated RAW 264.7 macrophages is attenuated by cAMP-induced gene expression

von Knethen, Andreas, Lotero, Alfredo, Brüne, Bernhard

Journal:

Year:

1998

Language:

english

File:

PDF, 501 KB

english, 1998

8

Attenuation of macrophage apoptosis by the cAMP-signalling system

Andreas von Knethen, Bernhard Brüne

Journal:

Molecular and Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 360 KB

english, 2000

9

OxLDL inhibits LPS-induced IFNβ expression by Pellino3- and IRAK1/4-dependent modification of TANK

Nico Tzieply, Anne-Marie Kuhn, Daniel Morbitzer, Dmitry Namgaladze, Annika Heeg, Liliana Schaefer, Andreas von Knethen, Liselotte E. Jensen, Bernhard Brüne

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 944 KB

english, 2012

10

Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages

Anne-Marie Kuhn, Nico Tzieply, Martina Victoria Schmidt, Andreas von Knethen, Dmitry Namgaladze, Masayuki Yamamoto, Bernhard Brüne

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

11

PPARγ stabilizes HO-1 mRNA in monocytes/macrophages which affects IFN-β expression

Andreas von Knethen, Holger Neb, Virginie Morbitzer, Martina Victoria Schmidt, Anne-Marie Kuhn, Laura Kuchler, Bernhard Brüne

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 923 KB

english, 2011

12

Nitric oxide and its role in apoptosis

Bernhard Brüne, Andreas von Knethen, Katrin B Sandau

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

13

Transcription factors p53 and HIF-1α as targets of nitric oxide

Bernhard Brüne, Andreas von Knethen, Katrin B. Sandau

Journal:

Cellular Signalling

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

14

Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism

Mohamed I. Hassan, Meike Boosen, Liliana Schaefer, Jowita Kozlowska, Florian Eisel, Andreas von Knethen, Martina Beck, Ramadan A. M. Hemeida, Mohamed A. M. El-Moselhy, Farid M. A. Hamada, Karl-Friedri

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

15

Cytokine and Low-Level Nitric Oxide Prestimulation Block p53 Accumulation and Apoptosis of Raw 264.7 Macrophages

Bernhard Brüne, Carsten Gölkel, Andreas von Knethen

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 941 KB

english, 1996

16

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

Careen Katryniok, Nicole Schnur, Ad Gillis, Andreas von Knethen, Bernd L. Sorg, Leendert Looijenga, Olof Rådmark, Dieter Steinhilber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

17

Crosstalk between the peroxisome proliferator-activated receptor γ (PPARγ) and the vitamin D receptor (VDR) in human breast cancer cells: PPARγ binds to VDR and inhibits 1α,25-dihydroxyvitamin D3 mediated transactivation

Alimirah, Fatouma, Peng, Xinjian, Yuan, Liang, Mehta, Rajeshwari R., von Knethen, Andreas, Choubey, Divaker, Mehta, Rajendra G.

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 915 KB

english, 2012

18

Redox Control of Inflammation in Macrophages

Brüne, Bernhard, Dehne, Nathalie, Grossmann, Nina, Jung, Michaela, Namgaladze, Dmitry, Schmid, Tobias, von Knethen, Andreas, Weigert, Andreas

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

19

5-Lipoxygenase contributes to PPARγ activation in macrophages in response to apoptotic cells

von Knethen, Andreas, Sha, Lisa K., Kuchler, Laura, Heeg, Annika K., Fuhrmann, Dominik, Heide, Heinrich, Wittig, Ilka, Maier, Thorsten J., Steinhilber, Dieter, Brüne, Bernhard

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 977 KB

english, 2013

20

Tumor-Endothelium Cross Talk Blocks Recruitment of Neutrophils to Endothelial Cells: A Novel Mechanism of Endothelial Cell Anergy

Blaheta, Roman A., Powerski, Maciej, Hudak, Lukasz, Juengel, Eva, Jonas, Dietger, von Knethen, Andreas, Doerr, Hans Willhelm, Cinatl, Jindrich

Journal:

Year:

2009

Language:

english

File:

PDF, 676 KB

english, 2009

21

Superinduction of Cyclooxygenase-2 by NO • and Agonist Challenge Involves Transcriptional Regulation Mediated by AP-1 Activation †

von Knethen, Andreas, Brüne, Bernhard

Journal:

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

22

PKCα Depletion in RAW264.7 Macrophages Following Microbial/IFNγ Stimulation Is PC-PLC-Mediated

Knethen, Andreas Von, Brüne, Bernhard

Journal:

Antioxidants & Redox Signaling

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

23

SYNCRIP-Dependent Nox2 mRNA Destabilization Impairs ROS Formation in M2-Polarized Macrophages

Kuchler, Laura, Giegerich, Annika Klara, Sha, Lisa Katharina, Knape, Tilo, Wong, Michael Sze Ka, Schröder, Katrin, Brandes, Ralf P., Heide, Heinrich, Wittig, Ilka, Brüne, Bernhard, von Knethen, Andrea

Journal:

Antioxidants & Redox Signaling

Year:

2014

Language:

english

File:

PDF, 825 KB

english, 2014

24

Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression

Giegerich, Annika Klara, Kuchler, Laura, Sha, Lisa Katharina, Knape, Tilo, Heide, Heinrich, Wittig, Ilka, Behrends, Christian, Brüne, Bernhard, Knethen, Andreas von

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

25

Cytokines induce protein kinase A-mediated signalling by a redox-dependent mechanism in rat renal mesangial cells

Beck, Karl-Friedrich, Euler, Johannes, Eisel, Florian, Beck, Martina, Köhler, Yvette, Sha, Lisa Katharina, von Knethen, Andreas, Longen, Sebastian, Pfeilschifter, Josef

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

26

Activation of the peroxisome proliferator-activated receptor γ counteracts sepsis-induced T cell cytotoxicity toward alloantigenic target cells

von Knethen, Andreas, Sha, Lisa Katharina, Knape, Tilo, Kuchler, Laura, Giegerich, Annika Klara, Schulz, Martin, Hauser, Ingeborg A., Brüne, Bernhard

Journal:

Journal of Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

27

Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8+ T cell function by limiting GSH and Cys availability

Sha, Lisa K., Sha, Weixiao, Kuchler, Laura, Daiber, Andreas, Giegerich, Annika K., Weigert, Andreas, Knape, Tilo, Snodgrass, Ryan, Schröder, Katrin, Brandes, Ralf P., Brüne, Bernhard, von Knethen, And

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

28

Ninjurin1 Promotes TLR4 Signaling and Contributes to Systemic Inflammation

Jennewein, Carla, Sowa, Ralf, Faber, Anne C, Dildey, Madlen, von Knethen, Andreas, Meybohm, Patrick, Scheller, Bertram, Dröse, Stefan, Zacharowski, Kai

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

29

Peroxisome Proliferator–activated Receptor γ–induced T Cell Apoptosis Reduces Survival during Polymicrobial Sepsis

Schmidt, Martina Victoria, Paulus, Patrick, Kuhn, Anne-Marie, Weigert, Andreas, Morbitzer, Virginie, Zacharowski, Kai, Kempf, Volkhard A. J., Brüne, Bernhard, von Knethen, Andreas

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

30

PPARγ1 Attenuates Cytosol to Membrane Translocation of PKCα to Desensitize Monocytes/Macrophages

Andreas von Knethen, Mathias Soller, Nico Tzieply, Andreas Weigert, Axel M. Johann, Carla Jennewein, Roman Köhl and Bernhard Brüne

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 3.40 MB

english, 2007

31

Macrophage activation by apoptotic cells

Brüne, Bernhard, von Knethen, Andreas

Journal:

BioInorganic Reaction Mechanisms

Year:

2013

Language:

english

File:

PDF, 2.43 MB

english, 2013

32

Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases

ZECH, Birgit, KÖHL, Roman, von KNETHEN, Andreas, BRÜNE, Bernhard

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 329 KB

english, 2003

33

Expression of p56 lck in B-Cell Neoplasias

Knethen, Andreas Von, Abts, Harry, Kube, Dieter, Diehl, Volker, Tesch, Hans

Journal:

Leukemia and Lymphoma

Year:

1997

Language:

english

File:

PDF, 1.16 MB

english, 1997

34

Apoptotic Diminution of Immature Single and Double Positive Thymocyte Subpopulations Contributes to Thymus Involution During Murine Polymicrobial Sepsis

Netzer, Christoph, Knape, Tilo, Kuchler, Laura, Weigert, Andreas, Zacharowski, Kai, Pfeilschifter, Waltraud, Sempowski, Gregory, Parnham, Michael J., Brüne, Bernhard, von Knethen, Andreas

Journal:

Year:

2017

Language:

english

File:

PDF, 1000 KB

english, 2017

35

Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis

Kuchler, Laura, Sha, Lisa K., Giegerich, Annika K., Knape, Tilo, Angioni, Carlo, Ferreirós, Nerea, Schmidt, Martina V., Weigert, Andreas, Brüne, Bernhard, von Knethen, Andreas

Journal:

Molecular Immunology

Year:

2017

Language:

english

File:

PDF, 865 KB

english, 2017

36

Redox-signals and macrophage biology (for the upcoming issue of molecular aspects of medicine on signaling by reactive oxygen species)

Weigert, Andreas, von Knethen, Andreas, Fuhrmann, Dominik, Dehne, Nathalie, Brüne, Bernhard

Journal:

Molecular Aspects of Medicine

Year:

2018

Language:

english

File:

PDF, 2.38 MB

english, 2018

37

CD69 Is a TGF-β/1α,25-dihydroxyvitamin D3 Target Gene in Monocytes

Wöbke, Thea K., von Knethen, Andreas, Steinhilber, Dieter, Sorg, Bernd L., Sanchez-Margalet, Victor

Journal:

Year:

2013

Language:

english

File:

PDF, 1.89 MB

english, 2013

38

Lipocalin-2 abrogates epithelial cell cycle arrest by PPARγ inhibition

Jung, Michaela, Brüne, Bernhard, von Knethen, Andreas, Guiteras, Roser, Cruzado, Josep Maria, Hotter, Georgina, Sola, Anna

Journal:

Laboratory Investigation

Year:

2018

Language:

english

File:

PDF, 3.00 MB

english, 2018

39

The Nuclear Hormone Receptor PPAR γ as a Therapeutic Target in Major Diseases

Schmidt, Martina Victoria, Brüne, Bernhard, von Knethen, Andreas

Journal:

The Scientific World JOURNAL

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

40

MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer

Olesch, Catherine, Sha, Weixiao, Angioni, Carlo, Sha, Lisa Katharina, Açaf, Elias, Patrignani, Paola, Jakobsson, Per-Johan, Radeke, Heinfried H., Grösch, Sabine, Geisslinger, Gerd, von Knethen, Andrea

Journal:

Year:

2015

Language:

english

File:

PDF, 3.07 MB

english, 2015

41

PD-L1 in the palm of your hand: palmitoylation as a target for immuno-oncology

von Knethen, Andreas, Brüne, Bernhard

Journal:

Signal Transduction and Targeted Therapy

Year:

2019

Language:

english

File:

PDF, 529 KB

english, 2019

42

Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation

Syed, Shahzad Nawaz, Raue, Rebecca, Weigert, Andreas, von Knethen, Andreas, Brüne, Bernhard

Journal:

Year:

2019

Language:

english

File:

PDF, 2.80 MB

english, 2019

43

NO-Evoked Macrophage Apoptosis Is Attenuated by cAMP-Induced Gene Expression

von Knethen, Andreas, Brockhaus, Florian, Kleiter, Ingo, Brüne, Bernhard

Journal:

Molecular Medicine

Year:

1999

File:

PDF, 2.41 MB

1999

44

Structure Optimization of a new class of PPARγ antagonists

Hernandez-Olmos, Victor, Knape, Tilo, Heering, Jan, von Knethen, Andreas, Kilu, Whitney, Kaiser, Astrid, Wurglics, Mario, Helmstädter, Moritz, Merk, Daniel, Schubert-Zsilavecz, Manfred, Parnham, Micha

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.71 MB

english, 2019

45

Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells

Trümper, Verena, von Knethen, Andreas, Preuß, Annegret, Ermilov, Eugeny, Hackbarth, Steffen, Kuchler, Laura, Gunne, Sandra, Schäfer, Anne, Bornhütter, Tobias, Vereb, György, Ujlaky-Nagy, Lázló, Brüne,

Journal:

Year:

2019

Language:

english

File:

PDF, 2.18 MB

english, 2019

46

Angiotensin II treatment in COVID-19 patients: more risk than benefit? A single-center experience

Heinicke, Ulrike, Adam, Elisabeth, Sonntagbauer, Michael, von Knethen, Andreas, Zacharowski, Kai, Neb, Holger

Journal:

Year:

2020

File:

PDF, 1.20 MB

2020

47

Redox Regulation of PPAR Î³ in Polarized Macrophages

TrÃ¼mper, Verena, Wittig, Ilka, Heidler, Juliana, Richter, Florian, BrÃ¼ne, Bernhard, von Knethen, Andreas

Journal:

Year:

2020

File:

PDF, 1.82 MB

2020

48

Macrophage-Derived Iron-Bound Lipocalin-2 Correlates with Renal Recovery Markers Following Sepsis-Induced Kidney Damage

Mertens, Christina, Kuchler, Laura, Sola, Anna, Guiteras, Roser, Grein, Stephan, BrÃ¼ne, Bernhard, von Knethen, Andreas, Jung, Michaela

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.59 MB

2020

49

Nrf2âA Molecular Target for Sepsis Patients in Critical Care

Gunne, Sandra, Heinicke, Ulrike, Parnham, Michael J., Laux, Volker, Zacharowski, Kai, von Knethen, Andreas

Journal:

Year:

2020

File:

PDF, 1.51 MB

2020