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51

A Chemical Screen Identifies Class A G-Protein Coupled Receptors As Regulators of Cilia

Avasthi, Prachee, Marley, Aaron, Lin, Henry, Gregori-Puigjane, Elisabet, Shoichet, Brian K., von Zastrow, Mark, Marshall, Wallace F.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.75 MB

english, 2012

52

Mass Spectrometric Analysis of Agonist Effects on Posttranslational Modifications of the β-2 Adrenoceptor in Mammalian Cells †

Trester-Zedlitz, Michelle, Burlingame, Al, Kobilka, Brian, von Zastrow, Mark

Journal:

Year:

2005

Language:

english

File:

PDF, 557 KB

english, 2005

53

Membrane traffic in the post-genomic era

Peter Hein,Mark von Zastrow

Journal:

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

54

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

Tsvetanova, Nikoleta G, von Zastrow, Mark

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 956 KB

english, 2014

55

Aripiprazole has Functionally Selective Actions at Dopamine D2 Receptor-Mediated Signaling Pathways

Urban, Jonathan D, Vargas, Gabriel A, von Zastrow, Mark, Mailman, Richard B

Journal:

Neuropsychopharmacology

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

56

Amplified RNA Synthesized from Limited Quantities of Heterogeneous cDNA

Russell N. Van Gelder, Mark E. von Zastrow, Andrea Yool, William C. Dement, Jack D. Barchas and James H. Eberwine

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.19 MB

english, 1990

57

G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes

Tsvetanova, Nikoleta G., Irannejad, Roshanak, von Zastrow, Mark

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 910 KB

english, 2015

58

Role of Mammalian Vacuolar Protein-sorting Proteins in Endocytic Trafficking of a Non-ubiquitinated G Protein-coupled Receptor to Lysosomes

Hislop, James N., Marley, Aaron, von Zastrow, Mark

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

59

The Golgi-associated PDZ Domain Protein PIST/GOPC Stabilizes the β1-Adrenergic Receptor in Intracellular Compartments after Internalization

Koliwer, Judith, Park, Minjong, Bauch, Carola, von Zastrow, Mark, Kreienkamp, Hans-Jürgen

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

60

Effects of endocytosis on receptor-mediated signaling

Irannejad, Roshanak, Tsvetanova, Nikoleta G, Lobingier, Braden T, von Zastrow, Mark

Journal:

Current Opinion in Cell Biology

Year:

2015

Language:

english

File:

PDF, 372 KB

english, 2015

61

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

Calebiro, Davide, Nikolaev, Viacheslav O., Gagliani, Maria Cristina, de Filippis, Tiziana, Dees, Christian, Tacchetti, Carlo, Persani, Luca, Lohse, Martin J., von Zastrow, Mark

Journal:

Year:

2009

Language:

english

File:

PDF, 2.46 MB

english, 2009

62

Association of Mu-Opioid Receptor Variants and Response to Citalopram Treatment in Major Depressive Disorder

Garriock, Holly A., Tanowitz, Michael, Kraft, Jeffrey B., Dang, Vu C., Peters, Eric J., Jenkins, Greg D., Reinalda, Megan S., McGrath, Patrick J., von Zastrow, Mark, Slager, Susan L., Hamilton, Steven

Journal:

American Journal of Psychiatry

Year:

2010

Language:

english

File:

PDF, 605 KB

english, 2010

63

Dynamin-Dependent Endocytosis of Ionotropic Glutamate Receptors

Reed C. Carroll, Eric C. Beattie, Houhui Xia, Christian Lüscher, Yoram Altschuler, Roger A. Nicoll, Robert C. Malenka and Mark von Zastrow

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.35 MB

english, 1999

64

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

Benjamin E.L. Lauffer, Cristina Melero, Paul Temkin, Cai Lei, Wanjin Hong, Tanja Kortemme and Mark von Zastrow

Journal:

The Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 2.58 MB

english, 2010

65

Distinct Dynamin-Dependent and -Independent Mechanisms Target Structurally Homologous Dopamine Receptors to Different Endocytic Membranes

Ross G. Vickery and Mark von Zastrow

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 4.08 MB

english, 1999

66

The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor

Tian, Xufan, Irannejad, Roshanak, Bowman, Shanna L., Du, Yang, Puthenveedu, Manojkumar A., von Zastrow, Mark, Benovic, Jeffrey L.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 7.56 MB

english, 2016

67

β-Blocker drugs mediate calcium signaling in native central nervous system neurons by β-arrestin—biased agonism

Anastassios V. Tzingounis, Mark von Zastrow, Guillermo A. Yudowski and Floyd Bloom

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

68

GIV/Girdin activates Gαi and inhibits Gαs via the same motif

Gupta, Vijay, Bhandari, Deepali, Leyme, Anthony, Aznar, Nicolas, Midde, Krishna K., Lo, I-Chung, Ear, Jason, Niesman, Ingrid, López-Sánchez, Inmaculada, Blanco-Canosa, Juan Bautista, von Zastrow, Mark

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

69

Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs

Varandas, Katherine C., Irannejad, Roshanak, von Zastrow, Mark

Journal:

Current Biology

Year:

2016

Language:

english

File:

PDF, 5.82 MB

english, 2016

70

G Protein–Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands

Tsvetanova, Nikoleta G., Trester-Zedlitz, Michelle, Newton, Billy W., Riordan, Daniel P., Sundaram, Aparna B., Johnson, Jeffrey R., Krogan, Nevan J., von Zastrow, Mark

Journal:

Molecular Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

71

Functional selectivity of GPCR-directed drug action through location bias

Irannejad, Roshanak, Pessino, Veronica, Mika, Delphine, Huang, Bo, Wedegaertner, Philip B, Conti, Marco, von Zastrow, Mark

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 4.99 MB

english, 2017

72

Distinct Dynamin-dependent and -independent Mechanisms Target Structurally Homologous Dopamine Receptors to Different Endocytic Membranes

Vickery, Ross G., von Zastrow, Mark

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 1.31 MB

english, 1999

73

Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity

Siljee, Jacqueline E., Wang, Yi, Bernard, Adelaide A., Ersoy, Baran A., Zhang, Sumei, Marley, Aaron, Von Zastrow, Mark, Reiter, Jeremy F., Vaisse, Christian

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.88 MB

english, 2018

74

Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras

Liang, Samantha I., van Lengerich, Bettina, Eichel, Kelsie, Cha, Minkwon, Patterson, David M., Yoon, Tae-Young, von Zastrow, Mark, Jura, Natalia, Gartner, Zev J.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.00 MB

english, 2018

75

Catalytic activation of β-arrestin by GPCRs

Eichel, Kelsie, Jullié, Damien, Barsi-Rhyne, Benjamin, Latorraca, Naomi R., Masureel, Matthieu, Sibarita, Jean-Baptiste, Dror, Ron O., von Zastrow, Mark

Journal:

Year:

2018

Language:

english

File:

PDF, 69.95 MB

english, 2018

76

Morphine Acutely Regulates Opioid Receptor Trafficking Selectively in Dendrites of Nucleus Accumbens Neurons

Haberstock-Debic, Helena, Wein, Marc, Barrot, Michel, Colago, Eric E. O., Rahman, Zia, Neve, Rachael L., Pickel, Virginia M., Nestler, Eric J., von Zastrow, Mark, Svingos, Adena L.

Journal:

Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 381 KB

english, 2003

77

Rapid, Activation-Induced Redistribution of Ionotropic Glutamate Receptors in Cultured Hippocampal Neurons

Lissin, Dmitri V., Carroll, Reed C., Nicoll, Roger A., Malenka, Robert C., Zastrow, Mark von

Journal:

Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 659 KB

english, 1999

78

Dysbindin Promotes the Post-Endocytic Sorting of G Protein-Coupled Receptors to Lysosomes

Marley, Aaron, von Zastrow, Mark, Keen, James

Journal:

Year:

2010

Language:

english

File:

PDF, 582 KB

english, 2010

79

A Simple Cell-Based Assay Reveals That Diverse Neuropsychiatric Risk Genes Converge on Primary Cilia

Marley, Aaron, von Zastrow, Mark, Saudou, Frédéric

Journal:

Year:

2012

Language:

english

File:

PDF, 705 KB

english, 2012

80

When trafficking and signaling mix: how subcellular location shapes GPCR activation of heterotrimeric G proteins

Lobingier, Braden T., von Zastrow, Mark

Journal:

Year:

2018

Language:

english

File:

PDF, 738 KB

english, 2018

81

μ-Opioid Receptors: Ligand-Dependent Activation of Potassium Conductance, Desensitization, and Internalization

Alvarez, Veronica A., Arttamangkul, Seksiri, Dang, Vu, Salem, Abdallah, Whistler, Jennifer L., von Zastrow, Mark, Grandy, David K., Williams, John T.

Journal:

Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

82

Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators

Patriarchi, Tommaso, Cho, Jounhong Ryan, Merten, Katharina, Marley, Aaron, Broussard, Gerard Joey, Liang, Ruqiang, Williams, John, Nimmerjahn, Axel, von Zastrow, Mark, Gradinaru, Viviana, Tian, Lin

Journal:

Nature Protocols

Year:

2019

Language:

english

File:

PDF, 7.31 MB

english, 2019

83

Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators

Patriarchi, Tommaso, Cho, Jounhong Ryan, Merten, Katharina, Marley, Aaron, Broussard, Gerard Joey, Liang, Ruqiang, Williams, John, Nimmerjahn, Axel, von Zastrow, Mark, Gradinaru, Viviana, Tian, Lin

Journal:

Nature Protocols

Year:

2019

File:

PDF, 7.31 MB

2019

84

A Discrete Presynaptic Vesicle Cycle for Neuromodulator Receptors

Jullié, Damien, Stoeber, Miriam, Sibarita, Jean-Baptiste, Zieger, Hanna L., Bartol, Thomas M., Arttamangkul, Seksiri, Sejnowski, Terrence J., Hosy, Eric, von Zastrow, Mark

Journal:

Year:

2019

File:

PDF, 3.14 MB

2019

85

Opioid pharmacology under the microscope

JulliÃ©, Damien, Gondin, Arisbel B, Von Zastrow, Mark E, Canals, Meritxell

Journal:

Molecular Pharmacology

Year:

2020

File:

PDF, 1.12 MB

2020

86

An expanded palette of dopamine sensors for multiplex imaging in vivo

Patriarchi, Tommaso, Mohebi, Ali, Sun, Junqing, Marley, Aaron, Liang, Ruqiang, Dong, Chunyang, Puhger, Kyle, Mizuno, Grace Or, Davis, Carolyn M., Wiltgen, Brian, von Zastrow, Mark, Berke, Joshua D., T

Journal:

Year:

2020

File:

PDF, 13.44 MB

2020

87

A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling

Semesta, Khairunnisa Mentari, Tian, Ruilin, Kampmann, Martin, von Zastrow, Mark, Tsvetanova, Nikoleta G., Schoofs, Liliane

Journal:

Year:

2020

File:

PDF, 3.41 MB

2020

88

Neurotrophin-Regulated Sorting of Opioid Receptors in the Biosynthetic Pathway of Neurosecretory Cells

Kim, Kyung-Ah, von Zastrow, Mark

Journal:

Journal of Neuroscience

Year:

2003

File:

PDF, 518 KB

2003