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1

S YNTHESIS AND F UNCTION OF 3- PHOSPHORYLATED I NOSITOL L IPIDS

Vanhaesebroeck, Bart, Leevers, Sally J., Ahmadi, Khatereh, Timms, John, Katso, Roy, Driscoll, Paul C., Woscholski, Rudiger, Parker, Peter J., Waterfield, Michael D.

Journal:

Annual Review of Biochemistry

Year:

2001

Language:

english

File:

PDF, 917 KB

english, 2001

2

Structural basis for epidermal growth factor receptor function

Hsuan, J.Justin, Panayotou, George, Waterfield, Michael D.

Journal:

Progress in Growth Factor Research

Year:

1989

Language:

english

File:

PDF, 750 KB

english, 1989

3

Adriamycin and 1-(2-Chlorethyl)-3-Cyclohexyl-1-Nitrosourea (CCNU) in the treatment of metastatic breast cancer

William C. Waterfield, Charles K. Tashima, Gabriel N. Hortobagyi, George R. Blumenschein, Aman U. Buzdar, Michael A. Burgess

Journal:

Year:

1978

Language:

english

File:

PDF, 354 KB

english, 1978

4

Cluster analysis of an extensive human breast cancer cell line protein expression map database

Robert A. Harris, Alice Yang, Robert C. Stein, Kevan Lucy, Luc Brusten, Athula Herath, Raj Parekh, Michael D. Waterfield, Michael J. O’Hare, Munro A. Neville, Martin J. Page, Marketa J. Zvelebil

Journal:

Year:

2002

Language:

english

File:

PDF, 3.75 MB

english, 2002

5

The assembly of signalling complexes by receptor tyrosine kinases

George Panayotou, Michael D. Waterfield

Journal:

Year:

1993

Language:

english

File:

PDF, 951 KB

english, 1993

6

Purification of Thy-1-related glycoproteins from human brain and fibroblasts: comparisons between these molecules and murine glycoproteins carrying Thy-1.1 and Thy-1.2 antigens

Susan F. Cotmore, Susan A. Crowhurst, Michael D. Waterfield

Journal:

European Journal of Immunology

Year:

1981

Language:

english

File:

PDF, 863 KB

english, 1981

7

Comparison of CD28-B7.1 and B7.2 functional interaction in resting human T cells: Phosphatidylinositol 3-kinase association to CD28 and cytokine production

Marguerite Ghiotto-Ragueneau, Michela Battifora, Alemsedeg Truneh, Michael D. Waterfield, Daniel Olive

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 966 KB

english, 1996

8

Expression of the c-erbB-2 protein in normal and transformed cells

William J. Gullick, Mark S. Berger, Paul L. P. Bennett, Jonathan B. Rothbard, Michael D. Waterfield

Journal:

International Journal of Cancer

Year:

1987

Language:

english

File:

PDF, 2.27 MB

english, 1987

9

A monoclonal antibody to the human epidermal growth factor receptor

Michael D. Waterfield, Elaine L. V. Mayes, Paul Stroobant, Paul L. P. Bennet, Susan Young, Peter N. Goodfellow, George S. Banting, Bradford Ozanne

Journal:

Journal of Cellular Biochemistry

Year:

1982

Language:

english

File:

PDF, 844 KB

english, 1982

10

Loss of three major auto phosphorylation sites in the EGF receptor does not block the mitogenic action of EGF

Stella Clark, Dorothy J. Cheng, J. Justin Hsuan, John D. Haley, Michael D. Waterfield

Journal:

Journal of Cellular Physiology

Year:

1988

Language:

english

File:

PDF, 930 KB

english, 1988

11

A protein sequencing device of simple construction

Michael D. Waterfield, Clare Corbett, Edgar Haber

Journal:

Analytical Biochemistry

Year:

1970

Language:

english

File:

PDF, 1.02 MB

english, 1970

12

A radioimmunoassay for human epidermal growth factor receptor

William J. Gullick, D.Julian H. Downward, Judith J. Marsden, Michael D. Waterfield

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 719 KB

english, 1984

13

ADepressionRecognition andTreatment package for families living withStroke(DepReT-Stroke): study protocol for a randomised controlled trial

Richard J Gray, Phyo K Myint, Frances Elender, Garry Barton, Michael Pfeil, Gill Price, Niki Wyatt, Garth Ravenhill, Ester Thomas, Jenny Jagger, Amelia Hursey, Kelly Waterfield, Sheila Hardy

Journal:

Year:

2011

Language:

english

File:

PDF, 261 KB

english, 2011

14

Epidermal growth factor receptors in lung tumours

Mark S. Berger, William J. Gullick, Charles Greenfield, Stuart Evans, Bruce J. Addis, Michael D. Waterfield

Journal:

The Journal of Pathology

Year:

1987

Language:

english

File:

PDF, 2.17 MB

english, 1987

15

Proteomic analysis of plasma membrane vesicles isolated from the rat renal cortex

Pedro R. Cutillas, Juerg Biber, Joanne Marks, Richard Jacob, Bruno Stieger, Rainer Cramer, Michael Waterfield, Alma L. Burlingame, Robert J. Unwin

Journal:

Year:

2005

Language:

english

File:

PDF, 466 KB

english, 2005

16

Stress-induced changes in the Schizosaccharomyces pombe proteome using two-dimensional difference gel electrophoresis, mass spectrometry and a novel integrated robotics platform

Mark E. Weeks, John Sinclair, Richard J. Jacob, Malcolm J. Saxton, Susan Kirby, James Jones, Michael D. Waterfield, Rainer Cramer, John F. Timms

Journal:

Year:

2005

Language:

english

File:

PDF, 533 KB

english, 2005

17

Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis

Hong-Lin Chan, Severine Gharbi, Piers R. Gaffney, Rainer Cramer, Michael D. Waterfield, John F. Timms

Journal:

Year:

2005

Language:

english

File:

PDF, 2.15 MB

english, 2005

18

Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol

Karin N. Barnouin, Sarah R. Hart, Andrew J. Thompson, Masahiro Okuyama, Michael Waterfield, Rainer Cramer

Journal:

Year:

2005

Language:

english

File:

PDF, 539 KB

english, 2005

19

A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe

Mark E. Weeks, John Sinclair, Amna Butt, Yuen-Li Chung, Jessica L. Worthington, Caroline R. M. Wilkinson, John Griffiths, Nic Jones, Michael D. Waterfield, John F. Timms

Journal:

Year:

2006

Language:

english

File:

PDF, 1.70 MB

english, 2006

20

Accelerated high-sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge

Nicholas F. Totty, J. Justin Hsuan, Michael D. Waterfield

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 814 KB

english, 1992

21

New insights into protein-tyrosine kinase receptor signaling complexes

Michael J. Fry, George Panayotou, Grant W. Booker, Michael D. Waterfield

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 4.86 MB

english, 1993

22

Isolation of a polymorphic genomic clone from chromosome 7

Kevin A. Davies, Laszlo Lorand, Michael Waterfield, Brandon Wainwright, Martin Farrall, Robert Williamson

Journal:

Year:

1987

Language:

english

File:

PDF, 771 KB

english, 1987

23

Clues to immune tolerance: the monogenic autoimmune syndromes

Michael Waterfield, Mark S. Anderson

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

24

10.1038/12075

Christoforidis, Savvas, Miaczynska, Marta, Ashman, Keith, Wilm, Matthias, Zhao, Liyun, Yip, Shu-Chin, Waterfield, Michael D., Backer, Jonathan M., Zerial, Marino

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 351 KB

english, 1999

25

Quantitative Approach to the Sequential Degradation of Proteins and Peptides

RICHARDS, FRANK F., BARNES, WILLIAM T., LOVINS, ROBERT E., SALOMONE, RAMON, WATERFIELD, MICHAEL D.

Journal:

Year:

1969

File:

PDF, 380 KB

1969

26

Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity

GETHING, MARY-JANE, KOSZINOWSKI, ULRICH, WATERFIELD, MICHAEL

Journal:

Year:

1978

File:

PDF, 317 KB

1978

27

Cloning and DNA sequence of double-stranded copies of haemagglutinin genes from H2 and H3 strains elucidates antigenic shift and drift in human influenza virus

Gething, Mary-Jane, Bye, Jackie, Skehel, John, Waterfield, Michael

Journal:

Year:

1980

File:

PDF, 800 KB

1980

28

Disulphide bonds of haemagglutinin of Asian influenza virus

Waterfield, Michael, Scrace, Geoffrey, Skehel, John

Journal:

Year:

1981

File:

PDF, 288 KB

1981

29

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

Waterfield, Michael D., Scrace, Geoffrey T., Whittle, Nigel, Stroobant, Paul, Johnsson, Ann, Wasteson, Åke, Westermark, Bengt, Heldin, Carl-Henrik, Huang, Jung San, Deuel, Thomas F.

Journal:

Year:

1983

File:

PDF, 732 KB

1983

30

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Libermann, Towia A., Nusbaum, Harris R., Razon, Nissim, Kris, Richard, Lax, Irit, Soreq, Hermona, Whittle, Nigel, Waterfield, Michael D., Ullrich, Axel, Schlessinger, Joseph

Journal:

Year:

1985

File:

PDF, 684 KB

1985

31

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

Noble, Mark, Murray, Kerren, Stroobant, Paul, Waterfield, Michael D., Riddle, Peter

Journal:

Year:

1988

File:

PDF, 480 KB

1988

32

Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase

Booker, Grant W., Breeze, Alexander L., Downing, A. Kristina, Panayotou, George, Gout, Ivan, Waterfield, Michael D., Campbell, Iain D.

Journal:

Year:

1992

File:

PDF, 536 KB

1992

33

Phosphatidylinositol-3-OH kinase direct target of Ras

Rodriguez-Viciana, Pablo, Warne, Patricia H., Dhand, Ritu, Vanhaesebroeck, Bart, Gout, Ivan, Fry, Michael J., Waterfield, Michael D., Downward, Julian

Journal:

Year:

1994

File:

PDF, 780 KB

1994

34

10.1038/9045

Vanhaesebroeck, Bart, Jones, Gareth E., Allen, William E., Zicha, Daniel, Hooshmand-Rad, Roya, Sawyer, Carol, Wells, Claire, Waterfield, Michael D., Ridley, Anne J.

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

35

10.1038/90454

Vanhaesebroeck, Bart, Jones, Gareth E., Allen, William E., Zicha, Daniel, Hooshmand-Rad, Roya, Sawyer, Carol, Wells, Claire, Waterfield, Michael D., Ridley, Anne J.

Journal:

Nature Neuroscience

Year:

2001

Language:

english

File:

PDF, 28 KB

english, 2001

36

A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

Jefferies, Harold B J, Cooke, Frank T, Jat, Parmjit, Boucheron, Christine, Koizumi, Tomonobu, Hayakawa, Masahiko, Kaizawa, Hiroyuki, Ohishi, Takahide, Workman, Paul, Waterfield, Michael D

Journal:

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

37

Identification of novel candidates for replicative senescence by functional proteomics

Benvenuti, Silvia, Cramer, Rainer, Bruce, Jim, Waterfield, Michael D, Jat, Parmjit S

Journal:

Year:

2002

Language:

english

File:

PDF, 493 KB

english, 2002

38

Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells

Timms, John F, White, Sarah L, O'Hare, Michael J, Waterfield, Michael D

Journal:

Year:

2002

Language:

english

File:

PDF, 447 KB

english, 2002

39

Identification of novel candidates for replicative senescence by functional proteomics

Benvenuti, Silvia, Cramer, Rainer, Bruce, Jim, Waterfield, Michael D, Jat, Parmjit S

Journal:

Year:

2002

Language:

english

File:

PDF, 42 KB

english, 2002

40

Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation

Arcaro, Alexandre, Khanzada, Umme K., Vanhaesebroeck, Bart, Tetley, Teresa D., Waterfield, Michael D., Seckl, Michael J.

Journal:

The EMBO Journal

Year:

2002

Language:

english

File:

PDF, 656 KB

english, 2002

41

Alternative modes of binding of proteins with tandem SH2 domains

Ronan O'Brien, Debora Renzoni, Michael D. Waterfield, Paul C. Driscoll, John E. Ladbury, Raj Handa, Kate Hilyard, Paul Rugman, Meredith Layto

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 356 KB

english, 2000

42

On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors

Mona Bajaj, Michael D. Waterfield, Joseph Schlessinger, William R. Taylor, Tom Blundell

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1987

Language:

english

File:

PDF, 505 KB

english, 1987

43

Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes

George Panayotou, Michael D. Waterfield

Journal:

Trends in Cell Biology

Year:

1992

Language:

english

File:

PDF, 361 KB

english, 1992

44

Phosphorylation of NF-κB1/p105 by oncoprotein kinase Tpl2: Implications for a novel mechanism of Tpl2 regulation

Geetha R. Babu, Wei Jin, Lourdes Norman, Michael Waterfield, Mikyoung Chang, Xuefeng Wu, Minying Zhang, Shao-Cong Sun

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2006

Language:

english

File:

PDF, 884 KB

english, 2006

45

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

Sally J Leevers, Bart Vanhaesebroeck, Michael D Waterfield

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

46

Three-dimensional solution structure of the pleckstrin homology domain from dynamin

A.Kristina Downing, Paul C. Driscoll, Ivan Gout, Kamran Salim, Markéta J. Zvelebil, Michael D. Waterfield

Journal:

Current Biology

Year:

1994

Language:

english

File:

PDF, 1.05 MB

english, 1994

47

Wiskott–Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

Sharon Banin, Oan Truong, David R. Katz, Michael D. Waterfield, Paul M. Brickell, Ivan Gout

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 408 KB

english, 1996

48

Receptor signalling: To Sevenless, a daughter

Lindsay K. MacDougall, Michael D. Waterfield

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 217 KB

english, 1996

49

A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction

Lindsay K. MacDougall, Jan Domin, Michael D. Waterfield

Journal:

Current Biology

Year:

1995

Language:

english

File:

PDF, 1.58 MB

english, 1995

50

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor

David Weinkove, Thomas P. Neufeld, Thomas Twardzik, Michael D. Waterfield, Sally J. Leevers

Journal:

Current Biology

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

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