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101

Human erythrocyte thiol methyltransferase: Radiochemical microassay and biochemical properties

Richard M. Weinshilboum, Susan Sladek, Susanne Klumpp

Journal:

Clinica Chimica Acta

Year:

1979

Language:

english

File:

PDF, 1.04 MB

english, 1979

102

Human platelet phenol sulphotransferase: Assay procedure, substrate and tissue correlations

Robert J. Anderson, Richard M. Weinshilboum, Sidney F. Phillips, Daniel D. Broughton

Journal:

Clinica Chimica Acta

Year:

1981

Language:

english

File:

PDF, 872 KB

english, 1981

103

Human erythrocyte histamine N-methyltransferase: radiochemical microassay and biochemical properties

Jon A. Van Loon, Patricio A. Pazmiño, Richard M. Weinshilboum

Journal:

Clinica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 1022 KB

english, 1985

104

Human liver nicotinamide N-methyltransferase: Ion-pairing radiochemical assay, biochemical properties and individual variation

Josephine Rini, Carol Szumlanski, Roberto Guerciolini, Richard M. Weinshilboum

Journal:

Clinica Chimica Acta

Year:

1990

Language:

english

File:

PDF, 1.07 MB

english, 1990

105

Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies

Michelle A.T. Hildebrandt, Oreste E. Salavaggione, Yvette N. Martin, Heather C. Flynn, Syed Jalal, Eric D. Wieben, Richard M. Weinshilboum

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 611 KB

english, 2004

106

Aggresome formation and pharmacogenetics: sulfotransferase 1A3 as a model system

Liewei Wang, Vivien C. Yee, Richard M. Weinshilboum

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 874 KB

english, 2004

107

Mycophenolic acid response biomarkers: A cell line model system-based genome-wide screen

Tse-Yu Wu, Brooke L. Fridley, Gregory D. Jenkins, Anthony Batzler, Liewei Wang, Richard M. Weinshilboum

Journal:

International Immunopharmacology

Year:

2011

Language:

english

File:

PDF, 1014 KB

english, 2011

108

Human 3β-hydroxysteroid dehydrogenase types 1 and 2: Gene sequence variation and functional genomics

Liewei Wang, Ezequiel Salavaggione, Linda Pelleymounter, Bruce Eckloff, Eric Wieben, Richard Weinshilboum

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 919 KB

english, 2007

109

Natriuretic peptide pharmacogenetics: Membrane metallo-endopeptidase (MME): Common gene sequence variation, functional characterization and degradation

Naveen L. Pereira, Pinar Aksoy, Irene Moon, Yi Peng, Margaret M. Redfield, John C. Burnett Jr., Eric D. Wieben, Vivien C. Yee, Richard M. Weinshilboum

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 1.62 MB

english, 2010

110

Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: Common gene sequence variation and functional characterization

Fang Li, Qiping Feng, Candace Lee, Shuzhan Wang, Linda L. Pelleymounter, Irene Moon, Bruce W. Eckloff, Eric D. Wieben, Daniel J. Schaid, Vivien Yee, Richard M. Weinshilboum

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 1.55 MB

english, 2008

111

Betaine-homocysteine methyltransferase: Human liver genotype–phenotype correlation

Qiping Feng, Krishna Kalari, Brooke L. Fridley, Gregory Jenkins, Yuan Ji, Ryan Abo, Scott Hebbring, Jianping Zhang, Monica D. Nye, J. Steven Leeder, Richard M. Weinshilboum

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

112

Mouse Nicotinamide N-Methyltransferase Gene: Molecular Cloning, Structural Characterization, and Chromosomal Localization

YAN, LAN, OTTERNESS, DIANE M., KOZAK, CHRISTINE A., WEINSHILBOUM, RICHARD M.

Journal:

DNA and Cell Biology

Year:

1998

Language:

english

File:

PDF, 420 KB

english, 1998

113

Thiopurine Methyltransferase Activity in Red Blood Cells of Dogs

Linda Benjamin Kidd, Oreste E. Salavaggione, Carol L. Szumlanski, Jackie L. Miller, Richard M. Weinshilboum, Lauren Trepanier

Journal:

Journal of Veterinary Internal Medicine

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

114

Electrophoretic analysis of low and high activity forms of catechol-O-methyltransferase in human erythrocytes

Mark H. Grossman, Carol Szumlanski, James B. Littrell, Ronald Weinstein, Richard M. Weinshilboum

Journal:

Year:

1992

Language:

english

File:

PDF, 766 KB

english, 1992

115

Sulfotransferase pharmacogenetics

Richard Weinshilboum

Journal:

Pharmacology & Therapeutics

Year:

1990

Language:

english

File:

PDF, 1.08 MB

english, 1990

116

Balsalazide and azathioprine or 6-mercaptopurine: Evidence for a potentially serious drug interaction

Philip W. Lowry, Carol L. Szumlanski, Richard M. Weinshilboum, William J. Sandborn

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 29 KB

english, 1999

117

Pharmacogenetics and Pharmacogenomics: Development, Science, and Translation

Weinshilboum, Richard M., Wang, Liewei

Journal:

Annual Review of Genomics and Human Genetics

Year:

2006

Language:

english

File:

PDF, 637 KB

english, 2006

118

The effect of lesions in the locus coeruleus on the physiological responses of the cerebral blood vessels in cats

David Bates, Richard M. Weinshilboum, R. Jean Campbell, Thoralf M. Sundt Jr.

Journal:

Year:

1977

Language:

english

File:

PDF, 1.27 MB

english, 1977

119

Human erythrocyte catechol-o-methyltransferase: Correlation with lung and kidney activity

Richard M. Weinshilboum

Journal:

Year:

1978

Language:

english

File:

PDF, 300 KB

english, 1978

120

Variations in catechol-O-methyltransferase activity in inbred strains of rats

Richard Weinshilboum, Fredrick Raymond

Journal:

Neuropharmacology

Year:

1977

Language:

english

File:

PDF, 361 KB

english, 1977

121

‘Methylator status’ and assessment of variation in drug metabolism

Richard M. Weinshilboum

Journal:

Trends in Pharmacological Sciences

Year:

1980

Language:

english

File:

PDF, 513 KB

english, 1980

122

N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis

Elena Ricart, William R Taylor, Edward V Loftus, Dennis O’Kane, Richard M Weinshilboum, William J Tremaine, W.Scott Harmsen, Alan R Zinsmeister, William J Sandborn

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

123

Mouse Liver Nicotinamide N-Methyltransferase:: cDNA Cloning, Expression, and Nucleotide Sequence Polymorphisms

Lan Yan, Diane M Otterness, Timothy L Craddock, Richard M Weinshilboum

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 773 KB

english, 1997

124

Thermal stability and the biochemical genetics of erythrocyte catechol-O-methyltransferase and plasma dopamine-β-hydroxylase

Richard Weinshilboum, Joel Dunnette

Journal:

Clinical Genetics

Year:

1981

Language:

english

File:

PDF, 934 KB

english, 1981

125

Pemetrexed and Oxaliplatin for Metastatic Colorectal Cancer: Results of a Phase I Mayo Cancer Center Research Consortium Trial, MC0248

Steven R. Alberts, George P. Kim, Michelle R. Mahoney, Michael K. Gornet, Joseph Rubin, Matthew Ames, Matthew P. Goetz, Richard M. Weinshilboum, Steven J. Nicol, Richard M. Goldberg

Journal:

Clinical Colorectal Cancer

Year:

2007

Language:

english

File:

PDF, 478 KB

english, 2007

126

Preemptive Genotyping for Personalized Medicine: Design of the Right Drug, Right Dose, Right Time—Using Genomic Data to Individualize Treatment Protocol

Bielinski, Suzette J., Olson, Janet E., Pathak, Jyotishman, Weinshilboum, Richard M., Wang, Liewei, Lyke, Kelly J., Ryu, Euijung, Targonski, Paul V., Van Norstrand, Michael D., Hathcock, Matthew A., T

Journal:

Mayo Clinic Proceedings

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

127

Investigation of a potential drug interaction between azathioprine (AZA)/6-mercaptopurine (6MP) and sulfasalazine (SAS), mesalamine (Pentasa) or balsalazide among patients with Crohn's disease (CD)

Lowry, Philip W., Franklin, Curtis L., Weaver, Amy L., Szumlanski, Carol L., Mays, Dennis C., Loftus, Edward V., Tremaine, William J., Lipsky, James J., Weinshilboum, Richard M., Sandborn, William J.

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

128

Human dehydroepiandrosterone sulfotransferase pharmacogenetics: Quantitative Western analysis and gene sequence polymorphisms

Wood, Thomas C., Her, Chengtao, Aksoy, Ibrahim, Otterness, Diane M., Weinshilboum, Richard M.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1996

Language:

english

File:

PDF, 1.21 MB

english, 1996

129

Inventing the NIH: Federal Biomedical Research Policy, 1887-1937

Weinshilboum, Richard M.

Journal:

Mayo Clinic Proceedings

Year:

1987

Language:

english

File:

PDF, 337 KB

english, 1987

130

Liver nicotinamide methylation: Nicotinamide N-methyltransferase expression in cirrhosis

Pumpo, Rossella, Buono, Pasqualina, Cuomo, Rosario, Salvatore, Francesco, Weinshilboum, Richard, Budillon, Gabriele

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 201 KB

english, 2000

131

The Genomic Revolution and Medicine

Weinshilboum, Richard M.

Journal:

Mayo Clinic Proceedings

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

132

Primer on Medical Genomics: Part XII: Pharmacogenomics—General Principles With Cancer as a Model

Goetz, Matthew P., Ames, Matthew M., Weinshilboum, Richard M.

Journal:

Mayo Clinic Proceedings

Year:

2004

Language:

english

File:

PDF, 101 KB

english, 2004

133

Serum dopamine β-hydroxylase activity in non-human primates: phylogenetic and genetic implications

Dunnette, Joel H., Weinshilboum, Richard M.

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1983

Language:

english

File:

PDF, 787 KB

english, 1983

134

Neurally Mediated Increase in Dopamine-β -hydroxylase Activity

Perry B. Molinoff, Steven Brimijoin, Richard Weinshilboum and Julius Axelrod

Journal:

Proceedings of the National Academy of Sciences

Year:

1970

Language:

english

File:

PDF, 643 KB

english, 1970

135

Enhanced Release of Dopamine-β -hydroxylase from Sympathetic Nerves by Calcium and Phenoxybenzamine and Its Reversal by Prostaglandins

David G. Johnson, Nguyen B. Thoa, Richard Weinshilboum, Julius Axelrod and Irwin J. Kopin

Journal:

Proceedings of the National Academy of Sciences

Year:

1971

Language:

english

File:

PDF, 583 KB

english, 1971

136

Structural Basis of Substrate Recognition in Thiopurine S -Methyltransferase †‡

Peng, Yi, Feng, Qiping, Wilk, Dennis, Adjei, Araba A., Salavaggione, Oreste E., Weinshilboum, Richard M., Yee, Vivien C.

Journal:

Year:

2008

Language:

english

File:

PDF, 12.43 MB

english, 2008

137

Thiopurine Methyltransferase Pharmacogenetics: Human Gene Cloning and Characterization of a Common Polymorphism

SZUMLANSKI, CAROL, OTTERNESS, DIANE, HER, CHENGTAO, LEE, DANIEL, BRANDRIFF, BRIGITTE, KELSELL, DAVID, SPURR, NIGEL, LENNARD, LYNNE, WIEBEN, ERIC, WEINSHILBOUM, RICHARD

Journal:

DNA and Cell Biology

Year:

1996

Language:

english

File:

PDF, 5.12 MB

english, 1996

138

Inheritance and Drug Response

Guttmacher, Alan E., Collins, Francis S., Weinshilboum, Richard

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

139

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system

Hartman, William R., Pelleymounter, Linda L., Moon, Irene, Kalari, Krishna, Liu, Mohan, Wu, Tse-Yu, Escande, Carlos, Nin, Veronica, Chini, Eduardo N., Weinshilboum, Richard M.

Journal:

Leukemia and Lymphoma

Year:

2010

Language:

english

File:

PDF, 863 KB

english, 2010

140

The Effect of CYP2D6 Drug-Drug Interactions on Hydrocodone Effectiveness

Monte, Andrew A., Heard, Kennon J., Campbell, Jenny, Hamamura, D., Weinshilboum, Richard M., Vasiliou, Vasilis, Bird, Steven

Journal:

Academic Emergency Medicine

Year:

2014

Language:

english

File:

PDF, 337 KB

english, 2014

141

Two-Phase Designs to Follow-Up Genome-Wide Association Signals With DNA Resequencing Studies

Schaid, Daniel J., Jenkins, Gregory D., Ingle, James N., Weinshilboum, Richard M.

Journal:

Genetic Epidemiology

Year:

2013

Language:

english

File:

PDF, 986 KB

english, 2013

142

Cardiovascular pharmacogenomics and individualized drug therapy

Pereira, Naveen L., Weinshilboum, Richard M.

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

143

N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis

Ricart, Elena, Taylor, William R., Loftus, Edward V., O'Kane, Dennis, Weinshilboum, Richard M., Tremaine, William J., Harmsen, W. Scott, Zinsmeister, Alan R., Sandborn, William J.

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

144

Genomics and Drug Response

Feero, W. Gregory, Guttmacher, Alan E., Wang, Liewei, McLeod, Howard L., Weinshilboum, Richard M.

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 804 KB

english, 2011

145

Platelet phenol sulfotransferase activity: Correlation with sulfate conjugation of acetaminophen

Reiter, Christoph, Weinshilboum, Richard

Journal:

Clinical Pharmacology & Therapeutics

Year:

1982

Language:

english

File:

PDF, 523 KB

english, 1982

146

Human Arsenic Methyltransferase (AS3MT) Pharmacogenetics

Wood, Thomas C., Salavagionne, Oreste E., Mukherjee, Baidehi, Wang, Liewei, Klumpp, Annette F., Thomae, Bianca A., Eckloff, Bruce W., Schaid, Daniel J., Wieben, Eric D., Weinshilboum, Richard M.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.45 MB

english, 2006

147

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes

Matimba, Alice, Li, Fang, Livshits, Alina, Cartwright, Cher S, Scully, Stephen, Fridley, Brooke L, Jenkins, Gregory, Batzler, Anthony, Wang, Liewei, Weinshilboum, Richard, Lennard, Lynne

Journal:

Pharmacogenomics

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

148

TPMT genetic variants are associated with increased rejection with azathioprine use in heart transplantation

Liang, Jackson J., Geske, Jennifer R., Boilson, Barry A., Frantz, Robert P., Edwards, Brooks S., Kushwaha, Sudhir S., Kremers, Walter K., Weinshilboum, Richard M., Pereira, Naveen L.

Journal:

Pharmacogenetics and Genomics

Year:

2013

Language:

english

File:

PDF, 500 KB

english, 2013

149

Dopamine-β-hydroxylase Activity in the Rat After Hypophysectomy

WEINSHILBOUM, RICHARD, AXELROD, JULIUS

Journal:

Year:

1970

Language:

english

File:

PDF, 616 KB

english, 1970

150

Pharmacogenomics: Bench to Bedside

Weinshilboum, Richard, Wang, Liewei

Journal:

Year:

2006

Language:

english

File:

PDF, 313 KB

english, 2006