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51

CommonCFTRgene variants influence body composition and survival in rural Ghana

Maris Kuningas, David van Bodegom, Linda May, Johannes J. Meij, P. Eline Slagboom, Rudi G. J. Westendorp

Journal:

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

52

Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study

Maris Kuningas, Simon P. Mooijaart, P. Eline Slagboom, Rudi G. J. Westendorp, Diana van Heemst

Journal:

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

53

Lipid metabolism in long-lived families: the Leiden Longevity Study

Anika A. M. Vaarhorst, Marian Beekman, Eka H. D. Suchiman, Diana van Heemst, Jeanine J. Houwing-Duistermaat, Rudi G. J. Westendorp, P. Eline Slagboom, Bastiaan T. Heijmans, On behalf of the project gr

Journal:

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

54

C-reactive protein and glucose regulation in familial longevity

Maarten P. Rozing, Simon P. Mooijaart, Marian Beekman, Carolien A. Wijsman, Andrea B. Maier, Andrzej Bartke, Rudi G.J. Westendorp, Eline P. Slagboom, Diana van Heemst

Journal:

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

55

Serum triiodothyronine levels and inflammatory cytokine production capacity

Maarten P. Rozing, Rudi G. J. Westendorp, Andrea B. Maier, Carolien A. Wijsman, Marijke Frölich, Anton J. M. de Craen, Diana van Heemst

Journal:

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

56

Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study

Carmen M. Martin-Ruiz, Jacobijn Gussekloo, Diana van Heemst, Thomas von Zglinicki, Rudi G. J. Westendorp

Journal:

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

57

Persistence of high-replicative capacity in cultured fibroblasts from nonagenarians

Andrea B. Maier, Saskia Le Cessie, Corine De Koning-Treurniet, Johanna Blom, Rudi G. J. Westendorp, Diana Van Heemst

Journal:

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

58

Genes encoding longevity: from model organisms to humans

Maris Kuningas, Simon P. Mooijaart, Diana Van Heemst, Bas J. Zwaan, P. Eline Slagboom, Rudi G. J. Westendorp

Journal:

Year:

2008

Language:

english

File:

PDF, 137 KB

english, 2008

59

Parallel lines: nothing has changed?

Maarten P. Rozing, Rudi G. J. Westendorp

Journal:

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

60

Stress-induced responses of human skin fibroblasts in vitro reflect human longevity

Pim Dekker, Andrea B. Maier, Diana Van Heemst, Corine De Koning-Treurniet, Joke Blom, Roeland W. Dirks, Hans J. Tanke, Rudi G.J. Westendorp

Journal:

Year:

2009

Language:

english

File:

PDF, 228 KB

english, 2009

61

Familial longevity is marked by enhanced insulin sensitivity

Carolien A. Wijsman, Maarten P. Rozing, Trea C. M. Streefland, Saskia le Cessie, Simon P. Mooijaart, P. Eline Slagboom, Rudi G. J. Westendorp, Hanno Pijl, Diana van Heemst, On behalf of the Leiden Lon

Journal:

Year:

2011

Language:

english

File:

PDF, 269 KB

english, 2011

62

Reduced insulin/IGF-1 signalling and human longevity

Diana Van Heemst, Marian Beekman, Simon P. Mooijaart, Bastiaan T. Heijmans, Bernd W. Brandt, Bas J. Zwaan, P. Eline Slagboom, Rudi G. J. Westendorp

Journal:

Year:

2005

Language:

english

File:

PDF, 87 KB

english, 2005

63

Systemic Markers of Inflammation and Cognitive Decline in Old Age

Miranda T. Schram, Sjoerd M. Euser, Anton J. M. De Craen, Jacqueline C. Witteman, Marijke Frölich, Albert Hofman, Jelle Jolles, Monique M. B. Breteler, Rudi G. J. Westendorp

Journal:

Journal of the American Geriatrics Society

Year:

2007

Language:

english

File:

PDF, 102 KB

english, 2007

64

Association Between Apolipoprotein E4 and Cognitive Decline in Elderly Adults

Chris J. Packard, Rudi G.J. Westendorp, David J. Stott, Muriel J. Caslake, Heather M. Murray, James Shepherd, Gerard J. Blauw, Michael B. Murphy, Edward L.E.M. Bollen, Brendan M. Buckley, Stuart M. Co

Journal:

Journal of the American Geriatrics Society

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

65

Hematopoietic Capacity and Exceptional Survival: The Leiden Longevity Study

Jorien M. Willems, Stella Trompet, P. Eline Slagboom, Anton J.M. De Craen, Rudi G.J. Westendorp

Journal:

Journal of the American Geriatrics Society

Year:

2008

Language:

english

File:

PDF, 141 KB

english, 2008

66

Does Low to Moderate Alcohol Intake Protect Against Cognitive Decline in Older People?

David J. Stott, Alison Falconer, Gillian D. Kerr, Heather M. Murray, Stella Trompet, Rudi G. J. Westendorp, Brendan Buckley, Anton J. M. De Craen, Naveed Sattar, Ian Ford

Journal:

Journal of the American Geriatrics Society

Year:

2008

Language:

english

File:

PDF, 158 KB

english, 2008

67

The Effect of Age on the Association Between Blood Pressure and Cognitive Function Later in Life

Sjoerd M. Euser, Thomas Van Bemmel, Miranda T. Schram, Jacobijn Gussekloo, Albert Hofman, Rudi G. J. Westendorp, Monique M. B. Breteler

Journal:

Journal of the American Geriatrics Society

Year:

2009

Language:

english

File:

PDF, 110 KB

english, 2009

68

Clinical Relevance of a Raised Plasma N-Terminal Pro-Brain Natriuretic Peptide Level in a Population-Based Cohort of Nonagenarians

Bert Vaes, Wouter De Ruijter, Jan Degryse, Rudi G. J. Westendorp, Jacobijn Gussekloo

Journal:

Journal of the American Geriatrics Society

Year:

2009

Language:

english

File:

PDF, 147 KB

english, 2009

69

Nonagenarian Siblings and Their Offspring Display Lower Risk of Mortality and Morbidity than Sporadic Nonagenarians: The Leiden Longevity Study

Rudi G.J. Westendorp, Diana Van Heemst, Maarten P. Rozing, Marijke Frölich, Simon P. Mooijaart, Gerard-Jan Blauw, Marian Beekman, Bastiaan T. Heijmans, Anton J.M. De Craen, P. Eline Slagboom, for the

Journal:

Journal of the American Geriatrics Society

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

70

Favorable Glucose Tolerance and Lower Prevalence of Metabolic Syndrome in Offspring without Diabetes Mellitus of Nonagenarian Siblings: The Leiden Longevity Study

Maarten P. Rozing, Rudi G. J. Westendorp, Anton J. M. De Craen, Marijke Frölich, Moniek C. M. De Goeij, Bastiaan T. Heijmans, Marian Beekman, Carolien A. Wijsman, Simon P. Mooijaart, Gerard-Jan Blauw,

Journal:

Journal of the American Geriatrics Society

Year:

2010

Language:

english

File:

PDF, 119 KB

english, 2010

71

PREDICTIVE VALUE OF LOW FERRITIN IN OLDER PERSONS WITH ANEMIA WITH AND WITHOUT INFLAMMATION: THE LEIDEN 85-PLUS STUDY

Wendy P.J. den Elzen, Jacobijn Gussekloo, Jorien M. Willems, Anton J.M. de Craen, Gerard J. Blauw, Gerard J. Blauw, Willem J.J. Assendelft, Rudi G.J. Westendorp

Journal:

Journal of the American Geriatrics Society

Year:

2010

Language:

english

File:

PDF, 89 KB

english, 2010

72

Ephelides are More Related to Pigmentary Constitutional Host Factors than Solar Lentigines

MAARTEN T.BASTIAENS, RUDI G.J. WESTENDORP, BERT J. VERMEER, JAN N. BOUWES BAVINCK

Journal:

Pigment Cell & Melanoma Research

Year:

1999

Language:

english

File:

PDF, 644 KB

english, 1999

73

Solar Lentigines are Strongly Related to Sun Exposure in Contrast to Ephelides

Maarten Bastiaens, Juliette Hoefnagel, Rudi Westendorp, Bert-Jan Vermeer, Jan Nico Bouwes Bavinck

Journal:

Pigment Cell & Melanoma Research

Year:

2004

Language:

english

File:

PDF, 115 KB

english, 2004

74

Genetics of Human Aging: The Search for Genes Contributing to Human Longevity and Diseases of the Old

P. ELINE SLAGBOOM, BASTIAAN T. HEIJMANS, MARIAN BEEKMAN, RUDI G.J. WESTENDORP, INGRID MEULENBELT

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 1.96 MB

english, 2000

75

10.1038/90868

Westendorp, Rudi G.J., van Dunne, Frederique M., Kirkwood, Tom B.L., Helmerhorst, Frans M., Huizinga, Tom W.J.

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 49 KB

english, 2001

76

Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana

May, Linda, van Bodegom, David, Frölich, Marijke, van Lieshout, Lisette, Slagboom, P Eline, Westendorp, Rudi GJ, Kuningas, Maris

Journal:

European Journal of Human Genetics

Year:

2009

Language:

english

File:

PDF, 372 KB

english, 2009

77

Mortality risk in men is associated with a common mutation in the methylenetetrahydrofolate reductase gene (MTHFR)

Heijmans, Bastiaan T, Gussekloo, Jacobijn, Kluft, Cornelis, Droog, Simone, Lagaay, A Margot, Knook, Dick L, Westendorp, Rudi GJ, Slagboom, Eline P

Journal:

European Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 134 KB

english, 1999

78

TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia

Mohrschladt, Martina F, van der Sman-de Beer, Femke, Hofman, Maaike K, van der Krabben, Marieke, Westendorp, Rudi GJ, Smelt, August HM

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

79

Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study

Schoenmaker, Manja, de Craen, Anton J M, de Meijer, Paul H E M, Beekman, Marian, Blauw, Gerard J, Slagboom, P Eline, Westendorp, Rudi G J

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 101 KB

english, 2005

80

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

Kuningas, Maris, Mägi, Reedik, Westendorp, Rudi G J, Slagboom, P Eline, Remm, Maido, van Heemst, Diana

Journal:

European Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

81

Are we becoming less disposable?

Westendorp, Rudi G.J.

Journal:

Year:

2004

Language:

english

File:

PDF, 65 KB

english, 2004

82

Cerebral Hemodynamics and White Matter Hyperintensities in CADASIL

van den Boom, Rivka, Lesnik Oberstein, Saskia A., Spilt, Aart, Behloul, Faiza, Ferrari, Michel D., Haan, Joost, Westendorp, Rudi G., van Buchem, Mark A.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

83

Regulation of Human Life Histories : The Role of the Inflammatory Host Response

DAVID VAN BODEGOM, LINDA MAY, HANS J. MEIJ, RUDI G. J. WESTENDORP

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 143 KB

english, 2007

84

Plasma Levels of Apolipoprotein E and Risk of Stroke in Old Age

PETER VAN VLIET, SIMON P. MOOIJAART, ANTON J. M. DE CRAEN, PATRICK C. N. RENSEN, DIANA VAN HEEMST, RUDI G. J. WESTENDORP

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 78 KB

english, 2007

85

Plasma Levels of Apolipoprotein E and Cognitive Function in Old Age

SIMON P. MOOIJAART, PETER VAN VLIET, DIANA VAN HEEMST, PATRICK C. N. RENSEN, JIMMY F. P. BERBÉE, JELLE JOLLES, ANTON J. M. DE CRAEN, RUDI G. J. WESTENDORP

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 139 KB

english, 2007

86

β-Galactosidase Activity as a Biomarker of Replicative Senescence during the Course of Human Fibroblast Cultures

ANDREA B. MAIER, RUDI G. J. WESTENDORP, DIANA VAN HEEMST

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

87

Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives

Postmus, Iris, Verschuren, Jeffrey JW, de Craen, Anton JM, Slagboom, P Eline, Westendorp, Rudi GJ, Jukema, J Wouter, Trompet, Stella

Journal:

Pharmacogenomics

Year:

2012

Language:

english

File:

PDF, 2.59 MB

english, 2012

88

Serum Calcium and Cognitive Function in Old Age

Miranda T. Schram, Stella Trompet, Adriaan M. Kamper, Anton J. M. De Craen, Albert Hofman, Sjoerd M. Euser, Monique M. B. Breteler, Rudi G. J. Westendorp

Journal:

Journal of the American Geriatrics Society

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

89

The Routine Electrocardiogram for Cardiovascular Risk Stratification in Old Age: The Leiden 85-Plus Study

Wouter De Ruijter, Rudi G. J. Westendorp, Peter W. Macfarlane, J. Wouter Jukema, Willem J. J. Assendelft, Jacobijn Gussekloo

Journal:

Journal of the American Geriatrics Society

Year:

2007

Language:

english

File:

PDF, 104 KB

english, 2007

90

The maintenance gap: a new theoretical perspective on the evolution of aging

Maarten J. Wensink, Diana van Heemst, Maarten P. Rozing, Rudi G. J. Westendorp

Journal:

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

91

Parental longevity correlates with offspring’s optimism in two cohorts of community-dwelling older subjects

Nathaly Rius-Ottenheim, Daan Kromhout, Anton J. M. de Craen, Johanna M. Geleijnse, Roos C. van der Mast, Frans G. Zitman, Rudi G. Westendorp, P. Eline Slagboom, Erik J. Giltay

Journal:

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

92

Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population

Carolina H.Y. Ling, Anton J.M. de Craen, Pieternella E. Slagboom, Dave A. Gunn, Marcel P.M. Stokkel, Rudi G.J. Westendorp, Andrea B. Maier

Journal:

Clinical Nutrition

Year:

2011

Language:

english

File:

PDF, 475 KB

english, 2011

93

Variation in the SHC1 gene and longevity in humans

Simon P Mooijaart, Diana van Heemst, Jeroen Schreuder, Suzan van Gerwen, Marian Beekman, Bernd W Brandt, P Eline Slagboom, Rudi G.J Westendorp, on behalf of the ‘Long Life’ study group

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

94

Basal cerebral blood flow is dependent on the nitric oxide pathway in elderly but not in young healthy men

Adriaan M Kamper, Aart Spilt, Anton J.M de Craen, Mark A van Buchem, Rudi G.J Westendorp, Gerard J Blauw

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 110 KB

english, 2004

95

Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study

Anita H.J. van den Biggelaar, Tom W.J. Huizinga, Anton J.M. de Craen, Jacobijn Gussekloo, Bastiaan T. Heijmans, Marijke Frölich, Rudi G.J. Westendorp

Journal:

Experimental Gerontology

Year:

2004

Language:

english

File:

PDF, 242 KB

english, 2004

96

Variation in the human TP53 gene affects old age survival and cancer mortality

Diana van Heemst, Simon P. Mooijaart, Marian Beekman, Jeroen Schreuder, Anton J.M. de Craen, Bernd W. Brandt, P. Eline Slagboom, Rudi G.J. Westendorp, on behalf of the ‘Long Life’ study group

Journal:

Experimental Gerontology

Year:

2005

Language:

english

File:

PDF, 131 KB

english, 2005

97

Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age

Anita H.J. van den Biggelaar, Jacobijn Gussekloo, Anton J.M. de Craen, Marijke Frölich, Max L. Stek, Roos C. van der Mast, Rudi G.J. Westendorp

Journal:

Experimental Gerontology

Year:

2007

Language:

english

File:

PDF, 171 KB

english, 2007

98

Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large

Simon P. Mooijaart, Kristel M.C. Koeijvoets, Eric J.G. Sijbrands, Mohamed R. Daha, Rudi G.J. Westendorp

Journal:

Experimental Gerontology

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

99

The influence of age on the association between cholesterol and cognitive function

Peter van Vliet, Willemien van de Water, Anton J.M. de Craen, Rudi G.J. Westendorp

Journal:

Experimental Gerontology

Year:

2009

Language:

english

File:

PDF, 1.94 MB

english, 2009

100

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies

Mette Soerensen, Serena Dato, Qihua Tan, Mikael Thinggaard, Rabea Kleindorp, Marian Beekman, Rune Jacobsen, H. Eka D. Suchiman, Anton J.M. de Craen, Rudi G.J. Westendorp, Stefan Schreiber, Tinna Stevn

Journal:

Experimental Gerontology

Year:

2012

Language:

english

File:

PDF, 255 KB

english, 2012