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51

Crystallographic Determination of Thrombin Complexes With Small Synthetic Inhibitors as a Starting Point for the Receptor-Based Design of Antithrombotics

Bauer, Margit, Brandstetter, Hans, Turk, Dusan, Stürzebecher, Jörg, Bode, Wolfram

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1993

Language:

english

File:

PDF, 1.75 MB

english, 1993

52

Handbook of Metalloproteins || Transferrins

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 682 KB

english, 2006

53

Handbook of Metalloproteins || Calsequestrin

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 950 KB

english, 2006

54

Handbook of Metalloproteins || Sulfite Reductase Hemoprotein

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 603 KB

english, 2006

55

Handbook of Metalloproteins || Gla-Domain

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 562 KB

english, 2006

56

Handbook of Metalloproteins || Ascorbate Oxidase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

57

Handbook of Metalloproteins || Trimethylamine N -Oxide Reductase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 465 KB

2006

58

Handbook of Metalloproteins || Cytochrome f /Plastocyanin Complex

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 373 KB

2006

59

Handbook of Metalloproteins || Octaheme Tetrathionate Reductase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 221 KB

2006

60

Handbook of Metalloproteins || Cytochrome P450

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 399 KB

2006

61

Macrocyclic Statine-Based Inhibitors of BACE-1

Alessandra Barazza, Marion Götz, Sergio A. Cadamuro, Peter Goettig, Michael Willem, Holger Steuber, Tanja Kohler, Anja Jestel, Peter Reinemer, Christian Renner, Wolfram Bode, Luis Moroder

Journal:

Year:

2007

Language:

english

File:

PDF, 696 KB

english, 2007

62

Determination of the Absolute Configuration of Peptide Natural Products by Using Stable Isotope Labeling and Mass Spectrometry

Prof. Dr. Helge B. Bode, Daniela Reimer, Dipl.-Biol. Sebastian W. Fuchs, Ferdinand Kirchner, Dipl.-Chem. Christina Dauth, Dr. Carsten Kegler, Dipl.-Pharm. Wolfram Lorenzen, Dr. Alexander O. Brachmann,

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 756 KB

english, 2012

63

Specific inhibition of insect α-amylases: yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolution

Pedro José Barbosa Pereira, Valentin Lozanov, András Patthy, Robert Huber, Wolfram Bode, Sándor Pongor, Stefan Strobl

Journal:

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

64

Natural protein proteinase inhibitors and their interaction with proteinases

Wolfram BODE, Robert HUBER

Journal:

Year:

1992

Language:

english

File:

PDF, 1.73 MB

english, 1992

65

Geometry of binding of the benzamidine- and arginine-based inhibitors Nα-(2-naphthyl-sulphonyl-glycyl)-dl-p-amidinophenylalanyl-piperidine (NAPAP) and (2R,4R)-4-methyl-1-[Nα-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulphonyl)-l-arginyl]-2-piperidine carboxylic acid (MQPA) to human α-thrombin : X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin

Wolfram BODE, Dušan TURK, Jörg STÜRZEBECHER

Journal:

Year:

1990

Language:

english

File:

PDF, 825 KB

english, 1990

66

Sequence and structure similarities of cathepsin B from the parasite Schistosoma mansoni and human liver

Mo-Quen Klinkert, Donato Cioli, Elliott Shaw, Vito Turk, Wolfram Bode, Richard Butler

Journal:

Year:

1994

Language:

english

File:

PDF, 297 KB

english, 1994

67

Crystal Structure of the Human Carboxypeptidase N (Kininase I) Catalytic Domain

Cora Keil, Klaus Maskos, Manuel Than, J. Todd Hoopes, Robert Huber, Fulong Tan, Peter A. Deddish, Ervin G. Erdös, Randal A. Skidgel, Wolfram Bode

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 3.02 MB

english, 2007

68

157 The “activation domain”: A highly cooperative entity within the catalytic domain of serine proteinases

Wolfram Bode, Doriano Lamba, Martin Renatus, Richard Engh

Journal:

Fibrinolysis and Proteolysis

Year:

1997

Language:

english

File:

PDF, 89 KB

english, 1997

69

The X-Ray Crystal Structure of Thrombin in Complex with Nα-2-Naphthylsulfonyl-L-3-Amidino-Phenylalanyl-4-Methylpiperidide: The Beneficial Effect of Filling Out an Empty Cavity

Bergner, Andreas, Bauer, Margit, Brandstetter, Hans, Stürzebecher, JÖRg, Bode, Wolfram

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 833 KB

english, 1995

70

Thrombin as a Multifunctional Protein: Induction of Cell Adhesion and Proliferation

Bar-Shavit, Rachel, Benezra, Miriam, Sabbah, Valerie, Bode, Wolfram, Vlodavsky, Israel

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1992

Language:

english

File:

PDF, 946 KB

english, 1992

71

Handbook of Metalloproteins || Protocatechuate 3,4-Dioxygenase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 484 KB

english, 2006

72

Handbook of Metalloproteins || Xanthine Oxidoreductase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 413 KB

english, 2006

73

Handbook of Metalloproteins || 4-Hydroxybutyryl-CoA Dehydratase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 510 KB

english, 2006

74

Handbook of Metalloproteins || Copper Nitrite Reductase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 379 KB

2006

75

Handbook of Metalloproteins || Inducible Nitric Oxide Synthase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 504 KB

2006

76

Handbook of Metalloproteins || EH Domain

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 464 KB

2006

77

Structure of a novel thrombin inhibitor with an uncharged d-amino acid as P1 residue

Rainer Friedrich, Daniel Riester, Peter Göttig, Marcel Thürk, Andreas Schwienhorst, Wolfram Bode

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

78

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc-peptidases

Walter Stöcker, Frank Grams, Peter Reinemer, Wolfram Bode, Ulrich Baumann, Franz-Xaver Gomis-Rüth, David B. Mckay

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 7.38 MB

english, 1995

79

The refined 2.2-Å (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor

Wolfram BODE, Jochen WALTER, Robert HUBER, Herbert R. WENZEL, Harald TSCHESCHE

Journal:

Year:

1984

Language:

english

File:

PDF, 660 KB

english, 1984

80

Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin

Milton T. Stubbs, Robert Huber, Wolfram Bode

Journal:

Year:

1995

Language:

english

File:

PDF, 498 KB

english, 1995

81

Rigidity and Flexibility of Dipeptidyl Peptidase IV: Crystal Structures of and Docking Experiments with DPIV

Michael Engel, Torsten Hoffmann, Susanne Manhart, Ulrich Heiser, Sylvie Chambre, Robert Huber, Hans-Ulrich Demuth, Wolfram Bode

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 998 KB

english, 2006

82

Corrigendum to “Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side Chain to Selectivity” [Journal of Molecular Biology, 371 (2007), 989–1006]

Anna Tochowicz, Klaus Maskos, Robert Huber, Ruth Oltenfreiter, Vincent Dive, Athanasios Yiotakis, Matteo Zanda, Tayebeh Pourmotabbed, Wolfram Bode, Peter Goettig

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

83

Catalytic Domain Structure of Vampire Bat Plasminogen Activator: A Molecular Paradigm for Proteolysis without Activation Cleavage

Renatus, Martin, Stubbs, Milton T., Huber, Robert, Bringmann, Peter, Donner, Peter, Schleuning, Wolf-Dieter, Bode, Wolfram

Journal:

Year:

1997

Language:

english

File:

PDF, 1.16 MB

english, 1997

84

Handbook of Metalloproteins || Insulin

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 478 KB

english, 2006

85

Handbook of Metalloproteins || Matrix Metalloproteinases

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 1019 KB

english, 2006

86

Handbook of Metalloproteins || Ceruloplasmin

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

87

Handbook of Metalloproteins || Structural Calcium (Trypsin, Subtilisin)

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 698 KB

english, 2006

88

Handbook of Metalloproteins || FtsH/HflB

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

89

Handbook of Metalloproteins || Tetraheme Cytochromes C 3

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 377 KB

2006

90

Handbook of Metalloproteins || 5-Aminolaevulinic Acid Dehydratase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 962 KB

2006

91

Handbook of Metalloproteins || Heme Oxygenase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 450 KB

2006

92

Handbook of Metalloproteins || Cytochrome c ��

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

File:

PDF, 399 KB

2006

93

Bivalent inhibition of human β-tryptase

Norbert Schaschke, Gabriele Matschiner, Frank Zettl, Ulf Marquardt, Andreas Bergner, Wolfram Bode, Christian P Sommerhoff, Luis Moroder

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 924 KB

english, 2001

94

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the ‘metzincins’

Wolfram Bode, Franz-Xaver Gomis-Rüth, Walter Stöckler

Journal:

Year:

1993

Language:

english

File:

PDF, 791 KB

english, 1993

95

The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA

Andreas Goette, Oliver Wolfram, Kathleen Jentsch-Ullrich, Jens Martens-Lobenhoffer, Fortunato Scalera, Uwe Lendeckel, Stefanie M. Bode-Böger

Journal:

International Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 434 KB

english, 2010

96

Handbook of Metalloproteins || Streptomyces Albus G D -Ala- D -Ala Carboxypeptidase

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

97

Structural Interaction of Natural and Synthetic Inhibitors with the Venom Metalloproteinase, Atrolysin C (Form d)

Dachuan Zhang, Istvan Botos, Franz-Xaver Gomis-Rüth, Ronald Doll, Christine Blood, F. George Njoroge, Jay w. Fox, Wolfram Bode and Edgar F. Meyer

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.87 MB

english, 1994

98

Handbook of Metalloproteins || Azurin and Azurin Mutants

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 727 KB

english, 2006

99

Determination of the Protein Content of Crystals Formed by Mastigocladus laminosus C-Phycocyanin, Chroomonas spec. Phycocyanin-645 and Modified Human Fibrinogen Using an Improved Ficoll Density Gradient Method

BODE, Wolfram, SCHIRMER, Tilman

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1985

Language:

english

File:

PDF, 1.90 MB

english, 1985

100

Handbook of Metalloproteins || Parvalbumin

Messerschmidt, Albrecht, Huber, Robert, Poulas, Thomas, Wieghardt, Karl, Cygler, Mirek, Bode, Wolfram

Year:

2006

Language:

english

File:

PDF, 208 KB

english, 2006

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