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51

Detection of 2-Amino-1-methyl-6-(4-hydroxyphenyl)imidazo[4,5-b]pyridine in Broiled Beef

Reiko Kurosaka, Keiji Wakabayashi, Hirofumi Ushiyama, Haruo Nukaya, Nobuhiko Arakawa, Takashi Sugimura, Minako Nagao

Journal:

Year:

1992

File:

PDF, 236 KB

1992

52

Adduct Formation at C-8 of Guanine on in vitro Reaction f the Ultimate Form of 2-Amino-l-methyl-6-phenylimidazo[4,5-b]pyridine with 2′-Deoxyguanosine and Its Phosphate Esters

Hiroaki Nagaoka, Keiji Wakabayashi, Seon-Bong Kim, In-Soo Kim, Yoshino Tanaka, Masako Ochiai, Akihiro Tada, Haruo Nukaya, Takashi Sugimura, Minako Nagao

Journal:

Year:

1992

File:

PDF, 306 KB

1992

53

Effects of Chronic Administration of Low Doses of 2-Ammo-3,8-dimethylimidazo-[4,5-f]qumoxaline on Glutathione S-Transferase Placental Form-positive Foci Development in the Livers of Rats Fed a Choline-deficient Diet

Hideko Sone, Keiji Wakabayashi, Hiromi Kushida, Masako Ochiai, Takashi Sugimura, Minako Nagao

Journal:

Year:

1993

File:

PDF, 390 KB

1993

54

Detection of Guanine-C8-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Adduct as a Single Spot on Thin-layer Chromatography by Modification of the 32P-Postlabeling Method

Kazuo Fukutome, Masako Ochiai, Keiji Wakabayashi, Shinya Watanabe, Takashi Sugimura, Minako Nagao

Journal:

Year:

1994

File:

PDF, 308 KB

1994

55

Formation and Removal of DNA Adducts in the Liver of Rats Chronically Fed the Food-borne Carcinogen, 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Misako Hirose, Keiji Wakabayashi, Masako Ochiai, Hiromi Kushida, Hidetaka Sato, Takashi Sugimura, Minako Nagao

Journal:

Year:

1995

File:

PDF, 485 KB

1995

56

Hepatocellular Carcinoma Induction in LEC Rats by a Low Dose of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Hideko Sone, Keiji Wakabayashi, Hiromi Kushida, Katsuhiko Enomoto, Michio Mori, Noritoshi Takeichi, Hiroyuki Tsuda, Takashi Sugimura, Minako Nagao

Journal:

Year:

1996

File:

PDF, 376 KB

1996

57

Rare Activation of the Human c-Ha-ras Transgene of Mice in Hemangioendothelial Sarcomas and Liver Tumors Induced by Glu-P-1

Rie Inoue, Toshikazu Ushijima, Makoto Katami, Hiromi Kushida, Keiji Wakabayashi, Hidetaka Sato, Makoto Asamoto, Motoya Katsuki, Takashi Sugimura, Minako Nagao

Journal:

Year:

1996

File:

PDF, 343 KB

1996

58

Presence in Pieris rapae of Cytotoxic Activity against Human Carcinoma Cells

Kotaro Koyama, Keiji Wakabayashi, Mitsuko Masutani, Kazunori Koiwai, Masahiko Watanabe, Shigeru Yamazaki, Takuo Kono, Keizaburo Miki, Takashi Sugimura

Journal:

Year:

1996

File:

PDF, 392 KB

1996

59

Helicobacter pylori Extracts Exhibit Nicotinamide Adenine Dinucleotide-derived Adenylation but Not Mono(adenosine 5-diphosphate-ribosyOation of DNA Ligase

Tadashige Nozaki, Mitsuko Masutani, Takeshi Noda, Daizo Saito, Toshiro Sugiyama, Tsuyoshi Takato, Keiji Wakabayashi, Hitoshi Nakagama, Takashi Sugimura

Journal:

Year:

1997

File:

PDF, 251 KB

1997

60

Suppression of Intestinal Polyp Development by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, in Min Mice

Seiichi Nakatsugi, Masato Fukutake, Mami Takahashi, Kazunori Fukuda, Takashi Isoi, Yasuaki Taniguchi, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

1997

File:

PDF, 473 KB

1997

61

RAPID COMMUNICATION : Suppression of Nitric Oxide Production in Lipopolysaccharide-stimulated Macrophage Cells by ω3 Polyunsaturated Fatty Acids

Takeji Ohata, Kazunori Fukuda, Mami Takahashi, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

1997

File:

PDF, 280 KB

1997

62

Inhibitory Effects of Diallyl Bisulfide or Aspirin on 2-Amino-l-methyl-6-phenylimidazo[4,5-b]pyridine-induced Mammary Carcinogenesis in Rats

Natsuko Suzui, Shigeyuki Sugie, K. M. Wahidur Rahman, Masami Ohnishi, Naoki Yoshimi, Keiji Wakabayashi, Hideki Mori

Journal:

Year:

1997

File:

PDF, 394 KB

1997

63

Purification of Pierisin, an Inducer of Apoptosis in Human Gastric Carcinoma Cells, from Cabbage Butterfly, Pieris rapae

Masahiko Watanabe, Takuo Kono, Kotaro Koyama, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

1998

Language:

english

File:

PDF, 239 KB

english, 1998

64

Inhibition by β-Carotene of Upper Respiratory Tumorigenesis in Hamsters Receiving Diethylnitrosamine Followed by Cigarette Smoke Exposure

Fumio Furukawa, Akiyoshi Nishikawa, Ken-ichiro Kasahara, In-Seon Lee, Keiji Wakabayashi, Michihito Takahashi, Masao Hirose

Journal:

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

65

Effects of a Soybean Isoflavone Mixture on Carcinogenesis in Prostate and Seminal Vesicles of F344 Rats

Mizuki Onozawa, Toshihiko Kawamori, Masaki Baba, Kazunori Fukuda, Toshiya Toda, Hidetaka Sato, Mikinobu Ohtani, Hideyuki Akaza, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

1999

Language:

english

File:

PDF, 108 KB

english, 1999

66

Lack of Carcinogenicity of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in Cynomolgus Monkeys

Kumiko Ogawa, Hiroyuki Tsuda, Tomoyuki Shirai, Tadashi Ogiso, Keiji Wakabayashi, Dan W. Dalgard, Unnur P. Thorgeirsson, Snorri S. Thorgeirsson, Richard H. Adamson, Takashi Sugimura

Journal:

Year:

1999

Language:

english

File:

PDF, 4.75 MB

english, 1999

67

Development and Distribution of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP)-induced Aberrant Crypt Foci in the Rat Large Intestine

Tetsuya Tsukamoto, Ken-ichi Kozaki, Yoko Nishikawa, Masami Yamamoto, Hiroko Fukami, Manami Inoue, Keiji Wakabayashi, Masae Tatematsu

Journal:

Year:

1999

Language:

english

File:

PDF, 5.87 MB

english, 1999

68

Chemoprevention by Nimesulide, a Selective Cyclooxygenase-2 Inhibitor, of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced Mammary Gland Carcinogenesis in Rats

Seiichi Nakatsugi, Toshihisa Ohta, Toshihiko Kawamori, Michihiro Mutoh, Tetsuya Tanigawa, Kouji Watanabe, Shigeyuki Sugie, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

69

Marked Enhancement by Fish Meal of Helicobacter pylori-induced Gastritis in Mongolian Gerbils

Tetsuya Tanigawa, Toshihiko Kawamori, Masaki Iimuro, Toshihisa Ohta, Kazuhide Higuchi, Tetsuo Arakawa, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2000

Language:

english

File:

PDF, 401 KB

english, 2000

70

More Frequent β-Catenin Gene Mutations in Adenomas than in Aberrant Crypt Foci or Adenocarcinomas in the Large Intestines of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated Rats

Tetsuya Tsukamoto, Harunari Tanaka, Hiroko Fukami, Manami Inoue, Mami Takahashi, Keiji Wakabayashi, Masae Tatematsu

Journal:

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

71

Suppression by Flavonoids of Cyclooxygenase-2 Promoter-dependent Transcriptional Activity in Colon Cancer Cells: Structure-Activity Relationship

Michihiro Mutoh, Mami Takahashi, Kazunori Fukuda, Hajime Komatsu, Takeji Enya, Yuko Matsushima-Hibiya, Hiroshi Mutoh, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2000

Language:

english

File:

PDF, 76 KB

english, 2000

72

Detection and Cloning of a Protein Recognized by Anti-human Prostate-specific Antigen (PSA) Antibody in the Rat Ventral Prostate

Mizuki Onozawa, Kazunori Fukuda, Masahiko Watanabe, Mikinobu Ohtani, Hideyuki Akaza, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2001

Language:

english

File:

PDF, 2.33 MB

english, 2001

73

Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPARγ ligand

Naoko Niho, Mami Takahashi, Yutaka Shoji, Yoshito Takeuchi, Satoshi Matsubara, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2003

Language:

english

File:

PDF, 1.07 MB

english, 2003

74

Combined effects of prostaglandin E receptor subtype EP1 and subtype EP4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice

Tomohiro Kitamura, Masaki Itoh, Tetsuo Noda, Kousuke Tani, Michiyoshi Kobayashi, Takayuki Maruyama, Kaoru Kobayashi, Shuichi Ohuchida, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

75

Cloning of Mongolian gerbil cDNAs encoding inflammatory proteins, and their expression in glandular stomach during H. pylori infection

Satoshi Matsubara, Hideyuki Shibata, Mami Takahashi, Fumiyasu Ishikawa, Teruo Yokokura, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2004

Language:

english

File:

PDF, 364 KB

english, 2004

76

Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish

Takashi Sugimura, Keiji Wakabayashi, Hitoshi Nakagama, Minako Nagao

Journal:

Year:

2004

Language:

english

File:

PDF, 2.48 MB

english, 2004

77

Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents

Mami Takahashi, Keiji Wakabayashi

Journal:

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

78

Suppression of azoxymethane-induced colon cancer development in rats by a prostaglandin E receptor EP1-selective antagonist

Naoko Niho, Michihiro Mutoh, Tomohiro Kitamura, Mami Takahashi, Hidetaka Sato, Hiroshi Yamamoto, Takayuki Maruyama, Shuichi Ohuchida, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2005

Language:

english

File:

PDF, 117 KB

english, 2005

79

Inhibition of intestinal carcinogenesis by a new flavone derivative, chafuroside, in oolong tea

Naoko Niho, Michihiro Mutoh, Katsuhisa Sakano, Mami Takahashi, Sachiko Hirano, Haruo Nukaya, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

80

Suppression of azoxymethane-induced colon cancer development in rats by a cyclooxygenase-1 selective inhibitor, mofezolac

Naoko Niho, Tomohiro Kitamura, Mami Takahashi, Michihiro Mutoh, Hidetaka Sato, Mamoru Matsuura, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2006

Language:

english

File:

PDF, 81 KB

english, 2006

81

‘On Environmental Carcinogens: From an Era of Risk Evaluation to an Era of Risk Management’ Tokyo, Japan, 29 July 2006

Okio Hino, Keiji Wakabayashi, Masae Tatematsu, Kazuo Tajima

Journal:

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

82

Genetic polymorphisms of cyclooxygenase-2 and colorectal adenoma risk: The Self Defense Forces Health Study

Naoyuki Ueda, Yoshihiko Maehara, Osamu Tajima, Shinji Tabata, Keiji Wakabayashi, Suminori Kono

Journal:

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

83

Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors

Tsukasa Kitahashi, Mami Takahashi, Yutaka Yamada, Yoichi Oghiso, Masanao Yokohira, Katsumi Imaida, Masahiro Tsutsumi, Nobuo Takasuka, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2008

Language:

english

File:

PDF, 153 KB

english, 2008

84

Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography

Yusaku Hori, Nobuo Takasuka, Michihiro Mutoh, Tsukasa Kitahashi, Shuji Kojima, Katsumi Imaida, Masahiro Suzuki, Kazushi Kohara, Shuji Yamamoto, Noriyuki Moriyama, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

85

Detection of endogenous DNA adducts, O6-carboxymethyl-2′-deoxyguanosine and 3-ethanesulfonic acid-2′-deoxycytidine, in the rat stomach after duodenal reflux

Masaru Terasaki, Yukari Totsuka, Koichi Nishimura, Ken-ichi Mukaisho, Kuan-Hao Chen, Takanori Hattori, Takeji Takamura-Enya, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2008

Language:

english

File:

PDF, 253 KB

english, 2008

86

Relationships between intestinal polyp formation and fatty acid levels in plasma, erythrocytes, and intestinal polyps in Min mice

Kiyonori Kuriki, Michihiro Mutoh, Kazuo Tajima, Keiji Wakabayashi, Masae Tatematsu

Journal:

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

87

Imaging study of pancreatic ductal adenocarcinomas in Syrian hamsters using X-ray micro-computed tomography (CT)

Tsukasa Kitahashi, Michihiro Mutoh, Masakatsu Tsurusaki, Gen Iinuma, Masahiro Suzuki, Noriyuki Moriyama, Mitsuyoshi Yoshimoto, Keiji Wakabayashi, Takashi Sugimura, Toshio Imai

Journal:

Year:

2010

Language:

english

File:

PDF, 570 KB

english, 2010

88

Increase of oxidant-related triglycerides and phosphatidylcholines in serum and small intestinal mucosa during development of intestinal polyp formation in Min mice

Kazutaka Ikeda, Michihiro Mutoh, Naoya Teraoka, Hiroki Nakanishi, Keiji Wakabayashi, Ryo Taguchi

Journal:

Year:

2011

Language:

english

File:

PDF, 432 KB

english, 2011

89

Functional importance of charged residues within the putative intracellular loops in pH regulation by Na+/ H+ exchanger NHE1

Takashi Hisamitsu, Keiji Yamada, Tomoe Y. Nakamura, Shigeo Wakabayashi

Journal:

Year:

2007

Language:

english

File:

PDF, 843 KB

english, 2007

90

Transfection of K-rasAsp12 cDNA markedly elevates IL-1β- and lipopolysaccharide-mediated inducible nitric oxide synthase expression in rat intestinal epithelial cells

Takahashi, Mami, Mutoh, Michihiro, Shoji, Yutaka, Kamanaka, Yoshihisa, Naka, Masao, Maruyama, Takayuki, Sugimura, Takashi, Wakabayashi, Keiji

Journal:

Year:

2003

Language:

english

File:

PDF, 351 KB

english, 2003

91

Function of poly(ADP-ribose) polymerase in response to DNA damage: Gene-disruption study in mice

Mitsuko Matsutani, Tadashige Nozaki, Eiko Nishiyama, Takashi Shimokawa, Yumiko Tachi, Hiroshi Suzuki, Hitoshi Nakagama, Keiji Wakabayashi, Takashi Sugimura

Journal:

Molecular and Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 73 KB

english, 1999

92

Preventive Effects of Cladosiphon Fucoidan Against Helicobacter pylori Infection in Mongolian gerbils

Hideyuki Shibata, Masaki Iimuro, Naoaki Uchiya, Toshihiko Kawamori, Masato Nagaoka, Sadao Ueyama, Shusuke Hashimoto, Teruo Yokokura, Takashi Sugimura, Keiji Wakabayashi

Journal:

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

93

COX-2 and iNOS, good targets for chemoprevention of colon cancer

Kouji Watanabe, Toshihiko Kawamori, Seiichi Nakatsugi, Keiji Wakabayashi

Journal:

Year:

2000

Language:

english

File:

PDF, 40 KB

english, 2000

94

In vivoexamination of the genotoxicity of the urban air and surface soil pollutant, 3,6-dinitrobenzo[e]pyrene, with intraperitoneal and intratracheal administration

Tatsuya Kato, Yukari Totsuka, Tomohiro Hasei, Tetsushi Watanabe, Keiji Wakabayashi, Naohide Kinae, Shuichi Masuda

Journal:

Environmental Toxicology

Year:

2012

Language:

english

File:

PDF, 195 KB

english, 2012

95

Testicular Toxicity in F344 Rats by Aminophenylnorharman, Formed from Norharman and Aniline

Yukari Totsuka, Toshihiko Kawamori, Shigeru Hisada, Kunitoshi Mitsumori, Junko Ishihara, Takashi Sugimura, Keiji Wakabayashi

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 691 KB

english, 2001

96

Suppression of azoxymethane-induced aberrant crypt foci in rat colon by nimesulide, a selective inhibitor of cyclooxygenase 2

Mami Takahashi, Masato Fukutake, Shigeru Yokota, Kaori Ishida, Keiji Wakabayashi, Takashi Sugimura

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1996

Language:

english

File:

PDF, 427 KB

english, 1996

97

Gastric carcinogenesis: Diet as a causative factor

Takashi Sugimura, Keiji Wakabayashi

Journal:

Medical Oncology

Year:

1990

Language:

english

File:

PDF, 1024 KB

english, 1990

98

Co-mutagenic effect of norharman with N-nitrosamine derivatives

Keiji Wakabayashi, Minako Nagao, Takashi Kawachi, Takashi Sugimura

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1981

Language:

english

File:

PDF, 370 KB

english, 1981

99

Formation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in a model system by heating creatinine, glycine and glucose

Margaretha Jägerstad, Kjell Olsson, Spiros Grivas, Chie Negishi, Keiji Wakabayashi, Mitsuhiro Tsuda, Sato Shigeaki, Sugimura Takashi

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1984

Language:

english

File:

PDF, 444 KB

english, 1984

100

Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods

Xue-Ming Zhang, Keiji Wakabayashi, Zhi-Chen Liu, Takashi Sugimura, Minako Nagao

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1988

Language:

english

File:

PDF, 644 KB

english, 1988