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1

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business

Joseph E. Wedekind, Geoffrey S.C. Dance, Mark.P. Sowden, Harold C. Smith

Journal:

Trends in Genetics

Year:

2003

Language:

english

File:

PDF, 455 KB

english, 2003

2

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Ghosh, Arun K., Sridhar, Perali Ramu, Leshchenko, Sofiya, Hussain, Azhar K., Li, Jianfeng, Kovalevsky, Andrey Yu., Walters, D. Eric, Wedekind, Joseph E., Grum-Tokars, Valerie, Das, Debananda, Koh, Yas

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 398 KB

english, 2006

3

Octahedral coordination at the high-affinity metal site in enolase: Crystallographic analysis of the MgII-enzyme complex from yeast at 1.9 .ANG. resolution

Wedekind, Joseph E., Reed, George H., Rayment, Ivan

Journal:

Year:

1995

Language:

english

File:

PDF, 1.90 MB

english, 1995

4

Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery

Chavali, Sai Shashank, Bonn-Breach, Rachel, Wedekind, Joseph E.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 8.30 MB

english, 2019

5

10.1038/6700

Wedekind, Joseph E., McKay, David B.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 702 KB

english, 1999

6

Riboswitch structure in the ligand-free state

Joseph A. Liberman, Joseph E. Wedekind

Journal:

Wiley Interdisciplinary Reviews: RNA

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

7

Functional characterization of APOBEC-1 complementation factor phosphorylation sites

David M. Lehmann, Chad A. Galloway, Celeste MacElrevey, Mark P. Sowden, Joseph E. Wedekind, Harold C. Smith

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2007

Language:

english

File:

PDF, 767 KB

english, 2007

8

Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world

Joseph A Liberman, Joseph E Wedekind

Journal:

Current Opinion in Structural Biology

Year:

2011

Language:

english

File:

PDF, 968 KB

english, 2011

9

The Apo Riboswitch as a Molecular Hydra

Joseph E. Wedekind

Journal:

Year:

2010

Language:

english

File:

PDF, 246 KB

english, 2010

10

Activation induced deaminase: the importance of being specific

Harold C. Smith, Andrea Bottaro, Mark P. Sowden, Joseph E. Wedekind

Journal:

Trends in Genetics

Year:

2004

Language:

english

File:

PDF, 97 KB

english, 2004

11

Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity

Joseph E Wedekind, Christine B Trame, Magdalena Dorywalska, Patrice Koehl, Tanya M Raschke, Marian McKee, David FitzGerald, R.John Collier, David B McKay

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 734 KB

english, 2001

12

APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic

Ryan P. Bennett, Elie Diner, Mark P. Sowden, Joshua A. Lees, Joseph E. Wedekind, Harold C. Smith

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 524 KB

english, 2006

13

Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme

Andrew T. Torelli, Robert C. Spitale, Jolanta Krucinska, Joseph E. Wedekind

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

14

Exploring ribozyme conformational changes with X-ray crystallography

Robert C. Spitale, Joseph E. Wedekind

Journal:

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

15

Structural and mechanistic studies of enolase

George H Reed, Russell R Poyner, Todd M Larsen, Joseph E Wedekind, Ivan Rayment

Journal:

Current Opinion in Structural Biology

Year:

1996

Language:

english

File:

PDF, 478 KB

english, 1996

16

Structure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor Complex

Wang, Wenhua, Maucuer, Alexandre, Gupta, Ankit, Manceau, Valérie, Thickman, Karen R., Bauer, William J., Kennedy, Scott D., Wedekind, Joseph E., Green, Michael R., Kielkopf, Clara L.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.23 MB

english, 2013

17

Molecular Mechanism of preQ 1 Riboswitch Action: A Molecular Dynamics Study

Banáš, Pavel, Sklenovský, Petr, Wedekind, Joseph E., Šponer, Jiří, Otyepka, Michal

Journal:

Journal of Physical Chemistry B

Year:

2012

Language:

english

File:

PDF, 2.46 MB

english, 2012

18

Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold

Liberman, Joseph A, Salim, Mohammad, Krucinska, Jolanta, Wedekind, Joseph E

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 965 KB

english, 2013

19

A Carboxylate Oxygen of the Substrate Bridges the Magnesium Ions at the Active Site of Enolase: Structure of the Yeast Enzyme Complexed with the Equilibrium Mixture of 2-Phosphoglycerate and Phosphoenolpyruvate at 1.8 Å Resolution †,‡

Larsen, Todd M., Wedekind, Joseph E., Rayment, Ivan, Reed, George H.

Journal:

Year:

1996

Language:

english

File:

PDF, 512 KB

english, 1996

20

Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for the μ-Crystallin Family †,‡

Goodman, Jessica L., Wang, Susan, Alam, Shabnam, Ruzicka, Frank J., Frey, Perry A., Wedekind, Joseph E.

Journal:

Year:

2004

Language:

english

File:

PDF, 1.04 MB

english, 2004

21

Crystal Structure of the Leadzyme at 1.8 Å Resolution: Metal Ion Binding and the Implications for Catalytic Mechanism and Allo Site Ion Regulation †

Wedekind, Joseph E., McKay, David B.

Journal:

Year:

2003

Language:

english

File:

PDF, 626 KB

english, 2003

22

Identification of an Imino Group Indispensable for Cleavage by a Small Ribozyme

Spitale, Robert C., Volpini, Rosaria, Heller, Moriah G., Krucinska, Jolanta, Cristalli, Gloria, Wedekind, Joseph E.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

23

Evidence for the Role of Active Site Residues in the Hairpin Ribozyme from Molecular Simulations along the Reaction Path

Heldenbrand, Hugh, Janowski, Pawel A., Giambaşu, George, Giese, Timothy J., Wedekind, Joseph E., York, Darrin M.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

24

Direct Raman Measurement of an Elevated Base p K a in the Active Site of a Small Ribozyme in a Precatalytic Conformation

Guo, Man, Spitale, Robert C., Volpini, Rosaria, Krucinska, Jolanta, Cristalli, Gloria, Carey, Paul R., Wedekind, Joseph E.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 145 KB

english, 2009

25

Efficient Syntheses of 5‘-Deoxy-5‘-fluoroguanosine and -inosine

Spitale, Robert C., Heller, Moriah G., Pelly, Amanda J., Wedekind, Joseph E.

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

26

Kinetic Evidence for Interaction of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with the 3‘-OH of the Incoming dTTP Substrate †

Jamburuthugoda, Varuni K., Guo, Dongdong, Wedekind, Joseph E., Kim, Baek

Journal:

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

27

Single-Atom Imino Substitutions at A9 and A10 Reveal Distinct Effects on the Fold and Function of the Hairpin Ribozyme Catalytic Core

Spitale, Robert C., Volpini, Rosaria, Mungillo, Michael V., Krucinska, Jolanta, Cristalli, Gloria, Wedekind, Joseph E.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.49 MB

english, 2009

28

A Hydrodynamic Analysis of APOBEC3G Reveals a Monomer−Dimer−Tetramer Self-Association That Has Implications for Anti-HIV Function

Salter, Jason D., Krucinska, Jolanta, Raina, Jay, Smith, Harold C., Wedekind, Joseph E.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.61 MB

english, 2009

29

The Structure of Nucleotidylated Histidine-166 of Galactose-1-phosphate Uridylyltransferase Provides Insight into Phosphoryl Group Transfer †,‡

Wedekind, Joseph E., Frey, Perry A., Rayment, Ivan

Journal:

Year:

1996

Language:

english

File:

PDF, 610 KB

english, 1996

30

The Enolase Superfamily: A General Strategy for Enzyme-Catalyzed Abstraction of the α-Protons of Carboxylic Acids †

Babbitt, Patricia C., Hasson, Miriam S., Wedekind, Joseph E., Palmer, David R. J., Barrett, William C., Reed, George H., Rayment, Ivan, Ringe, Dagmar, Kenyon, George L., Gerlt, John A.

Journal:

Year:

1996

Language:

english

File:

PDF, 991 KB

english, 1996

31

Three-Dimensional Structure of Galactose-1-phosphate Uridylyltransferase from Escherichia coli at 1.8 .ANG. Resolution

Wedekind, Joseph E., Frey, Perry A., Rayment, Ivan

Journal:

Year:

1995

Language:

english

File:

PDF, 4.57 MB

english, 1995

32

Peptide-Binding Motifs for the I-A d MHC Class II Molecule: Alternate pH-Dependent Binding Behavior †

Chaves, Francisco A., Richards, Katherine A., Torelli, Andrew, Wedekind, Joseph, Sant, Andrea J.

Journal:

Year:

2006

Language:

english

File:

PDF, 188 KB

english, 2006

33

Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn †,‡

Alam, Shabnam, Grum-Tokars, Valerie, Krucinska, Jolanta, Kundracik, Melisa L., Wedekind, Joseph E.

Journal:

Year:

2005

Language:

english

File:

PDF, 1.02 MB

english, 2005

34

A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis

Liberman, Joseph A., Guo, Man, Jenkins, Jermaine L., Krucinska, Jolanta, Chen, Yuanyuan, Carey, Paul R., Wedekind, Joseph E.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

35

Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer †,‡

Salter, Jason, Krucinska, Jolanta, Alam, Shabnam, Grum-Tokars, Valerie, Wedekind, Joseph E.

Journal:

Year:

2006

Language:

english

File:

PDF, 1.22 MB

english, 2006

36

Core-Binding Factor β Increases the Affinity between Human Cullin 5 and HIV-1 Vif within an E3 Ligase Complex

Salter, Jason D., Lippa, Geoffrey M., Belashov, Ivan A., Wedekind, Joseph E.

Journal:

Year:

2012

Language:

english

File:

PDF, 770 KB

english, 2012

37

Chelation of Serine 39 to Mg2+ Latches a Gate at the Active Site of Enolase: Structure of the Bis(Mg2+) Complex of Yeast Enolase and the Intermediate Analog Phosphonoacetohydroxamate at 2.1-.ANG. Resolution

Wedekind, Joseph E., Poyner, Russell R., Reed, George H., Rayment, Ivan

Journal:

Year:

1994

Language:

english

File:

PDF, 1.41 MB

english, 1994

38

Galactose-1-phosphate Uridylyltransferase from Escherichia coli, a Zinc and Iron Metalloenzyme

Ruzicka, Frank J., Wedekind, Joseph E., Kim, Jeongmin, Rayment, Ivan, Frey, Perry A.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.46 MB

english, 1995

39

CRYSTALLOGRAPHIC STRUCTURES OF THE HAMMERHEAD RIBOZYME: Relationship to Ribozyme Folding and Catalysis

Wedekind, Joseph E., McKay, David B.

Journal:

Annual Review of Biophysics and Biomolecular Structure

Year:

1998

Language:

english

File:

PDF, 798 KB

english, 1998

40

Efficacy of an equine joint supplement, and the synergistic effect of its active ingredients (chelated trace minerals and natural eggshell membrane), as demonstrated in equine, swine, and an osteoarthritis rat model

Evans, Joseph, Wedekind, Karen, Hampton, Thomas, Atwell, Cindy, Sorbert, Roy, Lunnemann, Jenea, Zhao, Junmei, Knight, Chris, Coverdale, Josie, Harrell, Robert, Greiner, Laura, Keith, Nancy

Journal:

Open Access Animal Physiology

Year:

2015

Language:

english

File:

PDF, 468 KB

english, 2015

41

Structural analysis of a class III preQ 1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

Liberman, Joseph A., Suddala, Krishna C., Aytenfisu, Asaminew, Chan, Dalen, Belashov, Ivan A., Salim, Mohammad, Mathews, David H., Spitale, Robert C., Walter, Nils G., Wedekind, Joseph E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 2.12 MB

english, 2015

42

AIP Conference Proceedings [AIP XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY - Boston (MA) (8–10 August 2010)] - Direct Raman Measurement of an Elevated Base pK[sub a] in the Active Site of a Small Ribozyme in a Pre-catalytic Conformation

Guo, Man, Spitale, Robert C., Volpini, Rosaria, Krucinska, Jolanta, Cristalli, Gloria, Carey, Paul R., Wedekind, Joseph E., Champion, P. M., Ziegler, L. D.

Year:

2010

Language:

english

File:

PDF, 115 KB

english, 2010

43

Molecular mechanism for preQ 1 -II riboswitch function revealed by molecular dynamics

Aytenfisu, Asaminew H., Liberman, Joseph A., Wedekind, Joseph E., Mathews, David H.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

44

Gene Regulation Gets in Tune: How Riboswitch Tertiary-Structure Networks Adapt to Meet the Needs of Their Transcription Units

Dutta, Debapratim, Wedekind, Joseph E.

Journal:

Journal of Molecular Biology

Year:

2015

Language:

english

File:

PDF, 776 KB

english, 2015

45

The Effects of Hospital Length of Stay on Readmissions for Children With Newly Diagnosed Acute Lymphoblastic Leukemia

Wedekind, Mary F., Dennis, Robyn, Sturm, Mollie, Koch, Terah, Stanek, Joseph, O’Brien, Sarah H.

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2016

Language:

english

File:

PDF, 137 KB

english, 2016

46

Superior growth performance in broiler chicks fed chelated compared to inorganic zinc in presence of elevated dietary copper

Zhao, Junmei, Shirley, Robert B., Dibner, Julia J., Wedekind, Karen J., Yan, Frances, Fisher, Paula, Hampton, Thomas R., Evans, Joseph L., Vazquez-Añon, Mercedes

Journal:

Journal of Animal Science and Biotechnology

Year:

2016

Language:

english

File:

PDF, 465 KB

english, 2016

47

Structural Characterization of Nitrosomonas europaea Cytochrome c -552 Variants with Marked Differences in Electronic Structure

Can, Mehmet, Krucinska, Jolanta, Zoppellaro, Giorgio, Andersen, Niels H., Wedekind, Joseph E., Hersleth, Hans-Petter, Andersson, K. Kristoffer, Bren, Kara L.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.94 MB

english, 2013

48

The effect of an irrelevant drive on maze learning in the rat.

Braun, Harry W., Wedekind, Carl E., Smudski, Joseph F.

Journal:

Journal of Experimental Psychology

Year:

1957

Language:

english

File:

PDF, 300 KB

english, 1957

49

Beneficial Effects of Natural Eggshell Membrane (NEM) on Multiple Indices of Arthritis in Collagen-Induced Arthritic Rats

Wedekind, Karen J., Ruff, Kevin J., Atwell, Cindy A., Evans, Joseph L., Bendele, Alison M.

Journal:

Modern Rheumatology

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

50

Metalloriboswitches: RNA-Based Inorganic Ion Sensors that Regulate Genes

Wedekind, Joseph E., Dutta, Debapratim, Belashov, Ivan A, Jenkins, Jermaine L.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 5.16 MB

english, 2017