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51

Body composition and survival in the early clinical trials setting

Veasey Rodrigues, H., Baracos, V.E., Wheler, J.J., Parsons, H.A., Hong, D.S., Naing, A., Fu, S., Falchoock, G., Tsimberidou, A.M., Piha-Paul, S., Chisholm, G., Kurzrock, R.

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 313 KB

english, 2013

52

18 Pursuing Molecular Stratification in Phase I Trials

Kurzrock, R., Tsimberidou, A.M., Hong, D.S., Wheler, J.J., Falchook, G.S., Fu, S., Naing, A., Janku, F., Wen, S., Berry, D.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 56 KB

english, 2012

53

Outcomes in 144 Patients With Colorectal Cancer Treated in a Phase I Clinic: The MD Anderson Cancer Center Experience

Hong, David S., Patel, Jesal C., Wheler, Jennifer, Naing, Aung, Garrido-Laguna, Ignacio, Falchook, Gerald, Fu, Siqing, Tsimberidou, Apostolia M., Kopetz, Scott, Win, Sijin, Kurzrock, Razelle

Journal:

Clinical Colorectal Cancer

Year:

2012

Language:

english

File:

PDF, 472 KB

english, 2012

54

246 Aberrations in PIK3CA, PTEN, and MAPK (KRAS, NRAS, BRAF) in 1,656 Patients and Experience with Early-phase Protocols with PI3K/AKT/mTOR Inhibitors

Janku, F., Hong, D.S., Fu, S., Piha-Paul, S.A., Naing, A., Falchook, G.S., Tsimberidou, A.M., Stepanek, V.M., Wheler, J.J., Kurzrock, R.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

55

Orthopedic conditions of the avian head

Wheler, Colette L

Journal:

Veterinary Clinics of North America: Exotic Animal Practice

Year:

2002

Language:

english

File:

PDF, 191 KB

english, 2002

56

Account of the Management of Bees on Mount Hymettus, in Greece

Journal:

The Belfast Monthly Magazine

Year:

1809

Language:

english

File:

PDF, 301 KB

english, 1809

57

A Letter from Mr. Stephen Gray, F. R. S. to the Publisher, Containing an Account of the Same Eclipse of the Sun, as Observed by Himself at Norton-Court: And at Otterden-Place, by Granville Wheler Esq; F. R. S. Both in Kent

Granville Wheler and Stephen Gray

Journal:

Philosophical Transactions (1665-1678)

Year:

1733-1734

Language:

english

File:

PDF, 297 KB

english, 1733-1734

58

Exploratory study of carboplatin plus the copper-lowering agent trientine in patients with advanced malignancies

Fu, Siqing, Hou, Ming-Mo, Wheler, Jennifer, Hong, David, Naing, Aung, Tsimberidou, Apostolia, Janku, Filip, Zinner, Ralph, Piha-Paul, Sarina, Falchook, Gerald, Kuo, Macus Tien, Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

59

Methylation and histone deacetylase inhibition in combination with platinum treatment in patients with advanced malignancies

Falchook, Gerald S., Fu, Siqing, Naing, Aung, Hong, David S., Hu, Wei, Moulder, Stacy, Wheler, Jennifer J., Sood, Anil K., Bustinza-Linares, Ernesto, Parkhurst, Kristin L., Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 274 KB

english, 2013

60

Evaluation of a novel blood pressure scoring method and its association with clinical response in cancer patients treated with anti-vascular endothelial growth factor therapy

Bilen, Mehmet Asim, Durand, Jean-Bernard, McQuinn, Lacey, Hess, Kenneth R., Fu, Siqing, Falchook, Gerald S., Hong, David S., Wheler, Jennifer J., Said, Rabih, Ewer, Michael S., Kurzrock, Razelle, Nain

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 187 KB

english, 2014

61

First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-κΒ and p70s6k, in patients with advanced solid tumors

Hong, D. S., Henary, H., Falchook, G. S., Naing, A., Fu, S., Moulder, S., Wheler, J. J., Tsimberidou, A., Durand, J. B., Khan, R., Yang, P., Johansen, M., Newman, R. A., Kurzrock, R.

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

62

An Account of Some of the Electrical Experiments Made by Granvile Wheler, Esq; at the Royal Society's House, on May 11. 1737. Drawn up by C. Mortimer, M. D. R. S. Secr

Granvile Wheler and C. Mortimer

Journal:

Philosophical Transactions (1665-1678)

Year:

1739-1741

Language:

english

File:

PDF, 678 KB

english, 1739-1741

63

A Letter from Granvile Wheler, Esq; To Dr. Mortimer, Secr. R. S. Containing Some Remarks on the Late Stephen Gray, F. R. S. His Electrical Circular Experiment

Granvile Wheler

Journal:

Philosophical Transactions (1665-1678)

Year:

1739-1741

Language:

english

File:

PDF, 921 KB

english, 1739-1741

64

Two Letters from the Rev. Mr. Granville Wheler, F. R. S. to the President, concerning a Rotatory Motion of Glass Tubes about Their Axes, When Placed in a Certain Manner before the Fire

Granville Wheler

Journal:

Philosophical Transactions (1665-1678)

Year:

1744-1745

Language:

english

File:

PDF, 1023 KB

english, 1744-1745

65

Personalized Medicine for Patients with Advanced Cancer in the Phase I Program at MD Anderson: Validation and Landmark Analyses

Tsimberidou, A.-M., Wen, S., Hong, D. S., Wheler, J. J., Falchook, G. S., Fu, S., Piha-Paul, S., Naing, A., Janku, F., Aldape, K., Ye, Y., Kurzrock, R., Berry, D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 614 KB

english, 2014

66

Effects of Temperature Forcing Provenance and Extrapolation on the Performance of an Empirical Glacier-Melt Model

Wheler, Brett A., MacDougall, Andrew H., Flowers, Gwenn E., Petersen, Eric I., Whitfield, Paul H., Kohfeld, Karen E.

Journal:

Arctic Antarctic and Alpine Research

Year:

2014

Language:

english

File:

PDF, 2.06 MB

english, 2014

67

Dual inhibition of the vascular endothelial growth factor pathway: A phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors

Hong, David S., Garrido-Laguna, Ignacio, Ekmekcioglu, Suhendan, Falchook, Gerald S., Naing, Aung, Wheler, Jennifer J., Fu, Siqing, Moulder, Stacy L., Piha-Paul, Sarina, Tsimberidou, Apostolia M., Wen,

Journal:

Year:

2014

Language:

english

File:

PDF, 349 KB

english, 2014

68

Photorearrangement of dimethoxytriptycene to methoxybenz[a]aceanthrylene

Day, Roberta O., Day, Victor W., Fuerniss, Stephen J., Wheler, Desmond M. S.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1975

Language:

english

File:

PDF, 151 KB

english, 1975

69

Southdown versus Suffolk sire breed effects on numbers and traits of crossbred lambs

Hohenboken, W.D, Clarke, J. N., Rattray, P. V., Smith, J. F., Wheler, M., Hohenboken, W.D.

Journal:

New Zealand Journal of Agricultural Research

Year:

1988

Language:

english

File:

PDF, 326 KB

english, 1988

70

Unique Molecular Landscapes in Cancer: Implications for Individualized, Curated Drug Combinations

Wheler, J., Lee, J. J., Kurzrock, R.

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 203 KB

english, 2014

71

Brentuximab Vedotin in Patients With CD30+ Mesothelioma

Jalal, S.I., Einhorn, L., Shapiro, G.I., Hilton, J., Wheler, J., Dowlati, A., Josephson, N., Sharman, J., Burke, J.M.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

72

MET Abnormalities in Patients With Genitourinary Malignancies and Outcomes With c-MET Inhibitors

Jardim, Denis L.F., de Melo Gagliato, Débora, Falchook, Gerald, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Tannir, Nizar, Corn, Paul, Tang, Cha

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 506 KB

english, 2015

73

Analysis of MET Genetic Aberrations in Patients With Breast Cancer at MD Anderson Phase I Unit

de Melo Gagliato, Debora, Jardim, Denis L. Fontes, Falchook, Gerald, Tang, Chad, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Hess, Kenneth, Roy-

Journal:

Clinical Breast Cancer

Year:

2014

Language:

english

File:

PDF, 234 KB

english, 2014

74

169 BRAF mutation testing in cell-free DNA from plasma of patients with advanced cancers using a novel, rapid, automated molecular diagnostics prototype platform (Idylla™)

Janku, F., Huang, H.J., Claes, B., Falchook, G.S., Naing, A., Piha-Paul, S., Tsimberidou, A.M., Zinner, R.G., Karp, D.D., Fu, S., Subbiah, V., Hong, D.S., Wheler, J.J., Luthra, R.G., Patel, S.P., Kope

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

75

Separation and Quantitation of O-Phthalaldehyde Derivatives of Taurine and Related Compounds in a High Performance Liquid Chromatography (HPLC) System

Wheler, G. H. T., Russell, J. T.

Journal:

Journal of Liquid Chromatography

Year:

1981

Language:

english

File:

PDF, 423 KB

english, 1981

76

Expression of estrogen and progesterone receptors across human malignancies: new therapeutic opportunities

Munoz, J., Wheler, J., Kurzrock, R.

Journal:

Cancer and Metastasis Reviews

Year:

2015

Language:

english

File:

PDF, 779 KB

english, 2015

77

Using dried blood spots stored on filter paper to measure cholinesterase activity in wild avian species

Trudeau, S., Mineau, P., Sans Cartier, G., Fitzgerald, G., Wilson, L., Wheler, C., Knopper, L. D.

Journal:

Year:

2007

Language:

english

File:

PDF, 162 KB

english, 2007

78

Personalized Medicine in a Phase I Clinical Trials Program: The MD Anderson Cancer Center Initiative

Tsimberidou, A.-M., Iskander, N. G., Hong, D. S., Wheler, J. J., Falchook, G. S., Fu, S., Piha-Paul, S., Naing, A., Janku, F., Luthra, R., Ye, Y., Wen, S., Berry, D., Kurzrock, R.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 603 KB

english, 2012

79

Dual antiangiogenic inhibition: a phase I dose escalation and expansion trial targeting VEGF-A and VEGFR in patients with advanced solid tumors

Falchook, Gerald S., Wheler, Jennifer J., Naing, Aung, Piha-Paul, Sarina A., Fu, Siqing, Tsimberidou, Apostolia M., Hong, David S., Janku, Filip, Zinner, Ralph, Jiang, Yunfang, Huang, Mei, Lin, Quan,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 652 KB

english, 2015

80

Olanzapine for cachexia in patients with advanced cancer: an exploratory study of effects on weight and metabolic cytokines

Naing, Aung, Dalal, Shalini, Abdelrahim, Maen, Wheler, Jennifer, Hess, Kenneth, Fu, Siqing, Hong, David S., Janku, Filip, Falchook, Gerald S., Ilustre, Alyson, Ouyang, Fengying, Kurzrock, Razelle

Journal:

Supportive Care in Cancer

Year:

2015

Language:

english

File:

PDF, 345 KB

english, 2015

81

Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation

Fu, S., Hou, M. M., Naing, A., Janku, F., Hess, K., Zinner, R., Subbiah, V., Hong, D., Wheler, J., Piha-Paul, S., Tsimberidou, A., Karp, D., Araujo, D., Kee, B., Hwu, P., Wolff, R., Kurzrock, R., Meri

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 183 KB

english, 2015

82

Combining Erlotinib and Cetuximab Is Associated with Activity in Patients with Non-Small Cell Lung Cancer (Including Squamous Cell Carcinomas) and Wild-Type EGFR or Resistant Mutations

Wheler, J. J., Tsimberidou, A. M., Falchook, G. S., Zinner, R. G., Hong, D. S., Fok, J. Y., Fu, S., Piha-Paul, S. A., Naing, A., Kurzrock, R.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 527 KB

english, 2013

83

Advance Care Planning in Patients With Cancer Referred to a Phase I Clinical Trials Program: The MD Anderson Cancer Center Experience

Fu, S., Barber, F. D., Naing, A., Wheler, J., Hong, D., Falchook, G., Piha-Paul, S., Tsimberidou, A., Howard, A., Kurzrock, R.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

84

Risk of serious toxicity in 1181 patients treated in phase I clinical trials of predominantly targeted anticancer drugs: the M. D. Anderson Cancer Center experience

Wheler, J. J., Tsimberidou, A. M., Hong, D. S., Naing, A., Falchook, G. S., Fu, S., Moulder, S., Stephen, B., Wen, S., Kurzrock, R.

Journal:

Annals of Oncology

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

85

A phase I trial of combination trastuzumab, lapatinib, and bevacizumab in patients with advanced cancer

Falchook, Gerald S., Moulder, Stacy, Naing, Aung, Wheler, Jennifer J., Hong, David S., Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Fu, Siqing, Zinner, Ralph, Janku, Filip, Jiang, Yunfang, Huang,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

86

Responses to Liposomal Doxorubicin, Bevacizumab, and Temsirolimus in Metaplastic Carcinoma of the Breast: Biologic Rationale and Implications for Stem-Cell Research in Breast Cancer

Moulder, S., Moroney, J., Helgason, T., Wheler, J., Booser, D., Albarracin, C., Morrow, P. K., Koenig, K., Kurzrock, R.

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 617 KB

english, 2011

87

Weekly nab-Rapamycin in Patients with Advanced Nonhematologic Malignancies: Final Results of a Phase I Trial

Gonzalez-Angulo, A. M., Meric-Bernstam, F., Chawla, S., Falchook, G., Hong, D., Akcakanat, A., Chen, H., Naing, A., Fu, S., Wheler, J., Moulder, S., Helgason, T., Li, S., Elias, I., Desai, N., Kurzroc

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 651 KB

english, 2013

88

Combination of Trastuzumab and Tanespimycin (17-AAG, KOS-953) Is Safe and Active in Trastuzumab-Refractory HER-2 Overexpressing Breast Cancer: A Phase I Dose-Escalation Study

Modi, S., Stopeck, A. T., Gordon, M. S., Mendelson, D., Solit, D. B., Bagatell, R., Ma, W., Wheler, J., Rosen, N., Norton, L., Cropp, G. F., Johnson, R. G., Hannah, A. L., Hudis, C. A.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 2.11 MB

english, 2007

89

Analysis of 1,115 Patients Tested for MET Amplification and Therapy Response in the MD Anderson Phase I Clinic

Jardim, D. L. F., Tang, C., Gagliato, D. D. M., Falchook, G. S., Hess, K., Janku, F., Fu, S., Wheler, J. J., Zinner, R. G., Naing, A., Tsimberidou, A. M., Holla, V., Li, M. M., Roy-Chowdhuri, S., Luth

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 285 KB

english, 2014

90

Phase I trial of valproic acid and lenalidomide in patients with advanced cancer

Bilen, Mehmet Asim, Fu, Siqing, Falchook, Gerald S., Ng, Chaan S., Wheler, Jennifer J., Abdelrahim, Maen, Erguvan-Dogan, Basak, Hong, David S., Tsimberidou, Apostolia M., Kurzrock, Razelle, Naing, Aun

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 359 KB

english, 2015

91

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

Hong, David S., Janku, Filip, Naing, Aung, Falchook, Gerald S., Piha-Paul, Sarina, Wheler, Jennifer J., Fu, Siqing, Tsimberidou, Apostolia M., Stecher, Michael, Mohanty, Prasant, Simard, John, Kurzroc

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

92

Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance

Wheler, Jennifer, Yelensky, Roman, Falchook, Gerald, Kim, Kevin B, Hwu, Patrick, Tsimberidou, Apostolia M, Stephens, Philip J, Hong, David, Cronin, Maureen T, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 995 KB

english, 2015

93

Nonlinear partial differential equations and applications: Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates

Strome, E. M., Wheler, G. H. T., Higley, J. D., Loriaux, D. L., Suomi, S. J., Doudet, D. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 333 KB

english, 2002

94

Inhibition of the phosphoinositide 3-kinase pathway for the treatment of patients with metastatic metaplastic breast cancer

Moulder, S., Helgason, T., Janku, F., Wheler, J., Moroney, J., Booser, D., Albarracin, C., Morrow, P. K., Atkins, J., Koenig, K., Gilcrease, M., Kurzrock, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

95

Tumor marker and measurement fluctuations may not reflect treatment efficacy in patients with medullary thyroid carcinoma on long-term RET inhibitor therapy

Kurzrock, R., Atkins, J., Wheler, J., Fu, S., Naing, A., Busaidy, N., Hong, D., Sherman, S.

Journal:

Annals of Oncology

Year:

2013

Language:

english

File:

PDF, 536 KB

english, 2013

96

Synergy Between VEGF/VEGFR Inhibitors and Chemotherapy Agents in the Phase I Clinic

Tang, C., Hess, K., Jardim, D. L. F., Gagliato, D. D. M., Tsimberidou, A. M., Falchook, G., Fu, S., Janku, F., Naing, A., Piha-Paul, S., Subbiah, V., Wheler, J., Zinner, R. G., Kurzrock, R., Ellis, L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 512 KB

english, 2014

97

Barriers to Study Enrollment in Patients With Advanced Cancer Referred to a Phase I Clinical Trials Unit

Fu, S., McQuinn, L., Naing, A., Wheler, J. J., Janku, F., Falchook, G. S., Piha-Paul, S. A., Tu, D., Howard, A., Tsimberidou, A., Zinner, R., Hong, D. S., Kurzrock, R.

Journal:

Year:

2013

Language:

english

File:

PDF, 424 KB

english, 2013

98

Phase I Clinical Trials in 56 Patients with Thyroid Cancer: The M. D. Anderson Cancer Center Experience

Tsimberidou, Apostolia Maria, Vaklavas, Christos, Wen, Sijin, Hong, David, Wheler, Jennifer, Ng, Chaan, Naing, Aung, Tse, Susan, Busaidy, Naifa, Markman, Maurie, Sherman, Steven I., Kurzrock, Razelle

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

99

Outcome Analyses After the First Admission to an Intensive Care Unit in Patients With Advanced Cancer Referred to a Phase I Clinical Trials Program

Fu, S., Hong, D. S., Naing, A., Wheler, J., Falchook, G., Wen, S., Howard, A., Barber, D., Nates, J., Price, K., Kurzrock, R.

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 111 KB

english, 2011

100

Large Animal Models for Vaccine Development and Testing

Gerdts, V., Wilson, H. L., Meurens, F., van Drunen Littel - van den Hurk, S., Wilson, D., Walker, S., Wheler, C., Townsend, H., Potter, A. A.

Journal:

Year:

2015

Language:

english

File:

PDF, 169 KB

english, 2015