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1

Experimentally determined hydrophobicity scale for proteins at membrane interfaces

Wimley, William C., White, Stephen H.

Journal:

Natural Structural Biology

Year:

1996

File:

PDF, 677 KB

1996

2

The versatile β-barrel membrane protein

William C Wimley

Journal:

Current Opinion in Structural Biology

Year:

2003

Language:

english

File:

PDF, 367 KB

english, 2003

3

Pituitary Adenylate Cyclase-Activating Polypeptide is a Potent Broad-Spectrum Antimicrobial Peptide: Structure-Activity Relationships

Starr, Charles G., Maderdrut, Jerome L., He, Jing, Coy, David H., Wimley, William C.

Journal:

Year:

2018

Language:

english

File:

PDF, 506 KB

english, 2018

4

Mechanistic Landscape of Membrane-Permeabilizing Peptides

Guha, Shantanu, Ghimire, Jenisha, Wu, Eric, Wimley, William C.

Journal:

Chemical Reviews

Year:

2019

Language:

english

File:

PDF, 26.43 MB

english, 2019

5

Anticancer and chemosensitizing abilities of cycloviolacin O2 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa

Samantha L. Gerlach, Ramesh Rathinakumar, Geetika Chakravarty, Ulf Göransson, William C. Wimley, Steven P. Darwin, Debasis Mondal

Journal:

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

6

A High-Throughput Screen for Identifying Transmembrane Pore-Forming Peptides

Joshua M. Rausch, William C. Wimley

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

7

Förster resonance energy transfer in liposomes: Measurements of transmembrane helix dimerization in the native bilayer environment

Min You, Edwin Li, William C. Wimley, Kalina Hristova

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 343 KB

english, 2005

8

Interactions between human defensins and lipid bilayers: Evidence for formation of multimeric pores

William C. Wimley, Michael E. Selsted, Stephen H. White

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 1.35 MB

english, 1994

9

A Look at Arginine in Membranes

Kalina Hristova, William C. Wimley

Journal:

Journal of Membrane Biology

Year:

2011

Language:

english

File:

PDF, 460 KB

english, 2011

10

Antimicrobial Peptides: Successes, Challenges and Unanswered Questions

William C. Wimley, Kalina Hristova

Journal:

Journal of Membrane Biology

Year:

2011

Language:

english

File:

PDF, 271 KB

english, 2011

11

Toward genomic identification of β-barrel membrane proteins: Composition and architecture of known structures

William C. Wimley

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 431 KB

english, 2002

12

Determining the mechanism of membrane permeabilizing peptides: Identification of potent, equilibrium pore-formers

Aram J. Krauson, Jing He, William C. Wimley

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2012

Language:

english

File:

PDF, 385 KB

english, 2012

13

A Highly Charged Voltage-Sensor Helix Spontaneously Translocates across Membranes

Dr. Jing He, Dr. Kalina Hristova, Dr. William C. Wimley

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

14

A Highly Charged Voltage-Sensor Helix Spontaneously Translocates across Membranes

Dr. Jing He, Dr. Kalina Hristova, Dr. William C. Wimley

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 981 KB

english, 2012

15

Hydrophobic interactions of peptides with membrane interfaces

Stephen H White, William C Wimley

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Year:

1998

Language:

english

File:

PDF, 368 KB

english, 1998

16

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1

Sibnarayan Datta, Sidhartha Hazari, Partha K Chandra, Maria Samara¹, Bret Poat, Feyza Gunduz, William C Wimley, Hansjorg Hauser, Mario Koster, Christophe Lamaze, Luis A Balart, Robert F Garry, Srikant

Journal:

Virology Journal

Year:

2011

Language:

english

File:

PDF, 2.66 MB

english, 2011

17

Folding of β-sheet membrane proteins: a hydrophobic hexapeptide model

William C. Wimley, Kalina Hristova, Alexey S. Ladokhin, Loraine Silvestro, Paul H. Axelsen, Stephen H. White

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 476 KB

english, 1998

18

An amphipathic α-helix at a membrane interface: a structural study using a novel X-ray diffraction method

Kalina Hristova, William C. Wimley, Vinod K. Mishra, G.M. Anantharamiah, Jere P. Segrest, Stephen H. White

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 651 KB

english, 1999

19

Folding of β-sheets in membranes: specificity and promiscuity in peptide model systems

Christopher M Bishop, William F Walkenhorst, William C Wimley

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 351 KB

english, 2001

20

Structure, function, and membrane integration of defensins

Stephen H White, William C Wimley, Michael E Selsted

Journal:

Current Opinion in Structural Biology

Year:

1995

Language:

english

File:

PDF, 821 KB

english, 1995

21

Characterization of antimicrobial peptide activity by electrochemical impedance spectroscopy

William K. Chang, William C. Wimley, Peter C. Searson, Kalina Hristova, Mikhail Merzlyakov

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 834 KB

english, 2008

22

Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization

William F. Walkenhorst, Mikhail Merzlyakov, Kalina Hristova, William C. Wimley

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

23

The prediction and characterization of YshA, an unknown outer-membrane protein from Salmonella typhimurium

Thomas C. Freeman Jr., Samuel J. Landry, William C. Wimley

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

24

Transmembrane helix dimerization: Beyond the search for sequence motifs

Edwin Li, William C. Wimley, Kalina Hristova

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2012

Language:

english

File:

PDF, 692 KB

english, 2012

25

Protein folding in membranes

William C. Wimley

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2012

Language:

english

File:

PDF, 117 KB

english, 2012

26

Reversible Unfolding of β-Sheets in Membranes: A Calorimetric Study

William C. Wimley, Stephen H. White

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

27

High-Throughput Selection of Transmembrane Sequences That Enhance Receptor Tyrosine Kinase Activation

Lijuan He, Andrew R. Hoffmann, Christopher Serrano, Kalina Hristova, William C. Wimley

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 551 KB

english, 2011

28

Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein

Bruno Sainz Jr., Eric C. Mossel, William R. Gallaher, William C. Wimley, C.J. Peters, Russell B. Wilson, Robert F. Garry

Journal:

Year:

2006

Language:

english

File:

PDF, 548 KB

english, 2006

29

Interactions of Membrane Active Peptides with Planar Supported Bilayers: An Impedance Spectroscopy Study

Lin, Janice, Motylinski, Jennifer, Krauson, Aram J., Wimley, William C., Searson, Peter C., Hristova, Kalina

Journal:

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

30

Non-membranolytic, Translocating Peptides Selected From A Peptide Library

marks, Jessica R., Wimley, William C.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

31

High Throughput Methods for Discovering Membrane Active Peptides

Rathinakumar, Ramesh, Marks, Jessica R., Krauson, Aram, Wimley, William C.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

32

Membrane-Active Peptides: Stable Pore-Forming or Cell-Penetrating Peptides Selected With Orthogonal High-Throughput Screening

Marks, Jessica R., Krauson, Aram J., Hristova, Kalina A., Wimley, William C.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010

33

Structural Plasticity in Self-Assembling Transmembrane β-Sheets

Bishop, Christopher M., Wimley, William C.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

34

Antimicrobial Peptides: Correlation Between Pore Forming Potency in Lipid Vesicles and Antimicrobial, Hemolytic and Cytotoxic Activity

He, Jing, Krauson, Aram, Wimley, Andrew W., Hoffmann, Andrew R., Wimley, William

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

35

Effect of Melittin and Gain-of-Function Melittin Analogs, Discovered by High-Throughput Screening, on Bilayer Properties: An Electrical Impedance Spectroscopy Study

Wiedman, Gregory, Wimley, William, Searson, Peter, Hristova, Kalina

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

36

Protein Folding in Membranes: Insights from Neutron Diffraction Studies of a Membrane β-Sheet Oligomer

Han, Xue, Hristova, Kalina, Wimley, William C.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

37

The electrical response of bilayers to the bee venom toxin melittin: Evidence for transient bilayer permeabilization

Wiedman, Gregory, Herman, Katherine, Searson, Peter, Wimley, William C., Hristova, Kalina

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2013

Language:

english

File:

PDF, 933 KB

english, 2013

38

MEMBRANE PROTEIN FOLDING AND STABILITY: Physical Principles

White, Stephen H., Wimley, William C.

Journal:

Annual Review of Biophysics and Biomolecular Structure

Year:

1999

Language:

english

File:

PDF, 810 KB

english, 1999

39

Synthetic Molecular Evolution of Pore-Forming Peptides by Iterative Combinatorial Library Screening

Krauson, Aram J., He, Jing, Wimley, Andrew W., Hoffmann, Andrew R., Wimley, William C.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.01 MB

english, 2013

40

The Preference of Tryptophan for Membrane Interfaces †

Yau, Wai-Ming, Wimley, William C., Gawrisch, Klaus, White, Stephen H.

Journal:

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

41

The Aromatic Domain of the Coronavirus Class I Viral Fusion Protein Induces Membrane Permeabilization: Putative Role during Viral Entry †

Sainz,, Bruno, Rausch, Joshua M., Gallaher, William R., Garry, Robert F., Wimley, William C.

Journal:

Year:

2005

Language:

english

File:

PDF, 605 KB

english, 2005

42

Broad-Spectrum Antimicrobial Peptides by Rational Combinatorial Design and High-Throughput Screening: The Importance of Interfacial Activity

Rathinakumar, Ramesh, Walkenhorst, William F., Wimley, William C.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 1.57 MB

english, 2009

43

A Membrane-Translocating Peptide Penetrates into Bilayers without Significant Bilayer Perturbations

Cruz, Juan, Mihailescu, Mihaela, Wiedman, Greg, Herman, Katherine, Searson, Peter C., Wimley, William C., Hristova, Kalina

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 872 KB

english, 2013

44

Designing Transmembrane α-Helices That Insert Spontaneously †

Wimley, William C., White, Stephen H.

Journal:

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

45

Solvation Energies of Amino Acid Side Chains and Backbone in a Family of Host−Guest Pentapeptides †

Wimley, William C., Creamer, Trevor P., White, Stephen H.

Journal:

Year:

1996

Language:

english

File:

PDF, 737 KB

english, 1996

46

Determining the Membrane Topology of Peptides by Fluorescence Quenching †

Wimley, William C., White, Stephen H.

Journal:

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

47

Describing the Mechanism of Antimicrobial Peptide Action with the Interfacial Activity Model

Wimley, William C.

Journal:

ACS Chemical Biology

Year:

2010

Language:

english

File:

PDF, 3.53 MB

english, 2010

48

Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity in living cells

He, Jing, Krauson, Aram J., Wimley, William C.

Journal:

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

49

Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein

Joshua M Costin, Joshua M Rausch, Robert F Garry, William C Wimley

Journal:

Virology Journal

Year:

2007

Language:

english

File:

PDF, 946 KB

english, 2007

50

Exchange and flip-flop of dimyristoyl phosphatidylcholine in liquid-crystalline, gel and two-component, two-phase large unilamellar vesicles

Wimley, William C., Thompson, T. E.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.01 MB

english, 1990