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51

Targeted Exon Skipping to Address “Leaky” Mutations in the Dystrophin Gene

Fletcher, Sue, Adkin, Carl F., Meloni, Penny, Wong, Brenda, Muntoni, Francesco, Kole, Ryszard, Fragall, Clayton, Greer, Kane, Johnsen, Russell, Wilton, Steve D.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

52

Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene

Greer, Kane L, Lochmüller, Hanns, Flanigan, Kevin, Fletcher, Susan, Wilton, Steve D

Journal:

Molecular Therapy — Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

53

[IEEE 2014 Conference on Optoelectronic and Microelectronic Materials & Devices (COMMAD) - Perth, Australia (2014.12.14-2014.12.17)] 2014 Conference on Optoelectronic and Microelectronic Materials & Devices - Embedding of quantum-dot cellular automata circuits onto a quantum annealing processor

Retallick, Jacob, Babcock, Michael, Aroca-Ouellette, Miguel, McNamara, Shane, Wilton, Steve, Roy, Aidan, Johnson, Mark, Walus, Konrad

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

54

Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping

Goyenvalle, Aurélie, Babbs, Arran, Powell, Dave, Kole, Ryszard, Fletcher, Sue, Wilton, Steve D, Davies, Kay E

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

55

RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes

Wilton, Steve, Fletcher, Susan

Journal:

Current Gene Therapy

Year:

2005

Language:

english

File:

PDF, 336 KB

english, 2005

56

[ACM Press the 2005 international symposium - San Diego, CA, USA (2005.08.08-2005.08.10)] Proceedings of the 2005 international symposium on Low power electronics and design - ISLPED '05 - Challenges and opportunities for low power FPGAs in nanometer technologies

He, Lei, Hutton, Mike, Tuan, Tim, Wilton, Steve

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

57

[ACM Press the 2007 ACM/SIGDA 15th international symposium - Monterey, California, USA (2007.02.18-2007.02.20)] Proceedings of the 2007 ACM/SIGDA 15th international symposium on Field programmable gate arrays - FPGA '07 - A synthesizable datapath-oriented embedded FPGA fabric

Wilton, Steve J. E., Ho, C. H., Leong, Philip H. W., Luk, Wayne, Quinton, Brad

Year:

2007

Language:

english

File:

PDF, 511 KB

english, 2007

58

[IEEE 2015 IEEE 23rd Annual International Symposium on Field-Programmable Custom Computing Machines (FCCM) - Vancouver, BC, Canada (2015.5.2-2015.5.6)] 2015 IEEE 23rd Annual International Symposium on Field-Programmable Custom Computing Machines - Using Dynamic Signal-Tracing to Debug Compiler-Optimized HLS Circuits on FPGAs

Goeders, Jeffrey, Wilton, Steve J.E.

Year:

2015

Language:

english

File:

PDF, 265 KB

english, 2015

59

The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow

de la Kethulle de Ryhove, Laurence, Ansseau, Eugénie, Nachtegael, Charlotte, Pieters, Karlien, Vanderplanck, Céline, Geens, Mieke, Sermon, Karen, Wilton, Steve D., Coppée, Frédérique, Lagneaux, Lauren

Journal:

Stem Cells and Development

Year:

2015

Language:

english

File:

PDF, 793 KB

english, 2015

60

Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicing

Fletcher, Sue, Adams, Abbie M, Johnsen, Russell D, Greer, Kane, Moulton, Hong M, Wilton, Steve D

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

61

Rational Design of Antisense Oligomers to Induce Dystrophin Exon Skipping

Mitrpant, Chalermchai, Adams, Abbie M, Meloni, Penny L, Muntoni, Francesco, Fletcher, Sue, Wilton, Steve D

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 283 KB

english, 2009

62

Antisense oligonucleotide development for the treatment of muscular dystrophies.

Bao, Tri Le, Veedu, Rakesh N, Fletcher, Sue, Wilton, Steve D

Journal:

Expert Opinion on Orphan Drugs

Year:

2015

Language:

english

File:

PDF, 887 KB

english, 2015

63

Correcting the NLRP3 inflammasome deficiency in macrophages from autoimmune NZB mice with exon skipping antisense oligonucleotides

Thygesen, Sara J, Sester, David P, Cridland, Simon O, Wilton, Steve D, Stacey, Katryn J

Journal:

Immunology & Cell Biology

Year:

2016

Language:

english

File:

PDF, 847 KB

english, 2016

64

Pseudoexon activation increases phenotype severity in a Becker muscular dystrophy patient

Greer, Kane, Mizzi, Kayla, Rice, Emily, Kuster, Lukas, Barrero, Roberto A., Bellgard, Matthew I., Lynch, Bryan J., Foley, Aileen Reghan, O Rathallaigh, Eoin, Wilton, Steve D., Fletcher, Sue

Journal:

Molecular Genetics & Genomic Medicine

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

65

[IEEE 2015 IEEE International Parallel and Distributed Processing Symposium Workshop (IPDPSW) - Hyderabad, India (2015.5.25-2015.5.29)] 2015 IEEE International Parallel and Distributed Processing Symposium Workshop - RAW Introduction and Committees

Becker, Jurgen, Eguro, Ken, Gohringer, Diana, Luk, Wayne, Santambrogio, Marco D., Vaidyanathan, Ramachandran, Wilton, Steve

Year:

2015

Language:

english

File:

PDF, 112 KB

english, 2015

66

Morpholino Oligomer Peptide Therapy Improves Mitochondrial Function in mdx Cardiomyopathy

Johnstone, Victoria P., Adams, Abbie M., Wilton, Steve D., Fletcher, Sue, Hool, Livia C.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 72 KB

english, 2015

67

Part 2: Making the “unproven” “proven”

Weiss, Daniel J., Rasko, John E.J., Cuende, Natividad, Ruiz, Milton A., Ho, Hong-Nerng, Nordon, Robert, Wilton, Steve, Dominici, Massimo, Srivastava, Alok

Journal:

Year:

2016

Language:

english

File:

PDF, 580 KB

english, 2016

68

Inferring the variation of climatic and glaciological contributions to West Greenland iceberg discharge in the twentieth century

Zhao, Yifan, Bigg, Grant R., Billings, Steve A., Hanna, Edward, Sole, Andrew J., Wei, Hua-liang, Kadirkamanathan, Visakan, Wilton, David J.

Journal:

Cold Regions Science and Technology

Year:

2016

Language:

english

File:

PDF, 1.91 MB

english, 2016

69

Gene therapy and molecular approaches to the treatment of hereditary muscular disorders

Fletcher, Susan, Wilton, Steve D., Howell, John McC.

Journal:

Current Opinion in Neurology

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

70

[IEEE 2008 IEEE Custom Integrated Circuits Conference - CICC 2008 - San Jose, CA, USA (2008.09.21-2008.09.24)] 2008 IEEE Custom Integrated Circuits Conference - Session 14 - Advanced SoCs - techniques and applications

Wilton, Steve, Rahman, Arif

Year:

2008

Language:

english

File:

PDF, 126 KB

english, 2008

71

Splice Modification to Restore Functional Dystrophin Synthesis in Duchenne Muscular Dystrophy

Wilton, Steve., Fletcher, Susan

Journal:

Current Pharmaceutical Design

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

72

RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes

D. Wilton, Steve, Fletcher, Susan

Journal:

Current Gene Therapy

Year:

2011

Language:

english

File:

PDF, 427 KB

english, 2011

73

SPIE Proceedings [SPIE SPIE's 1993 International Symposium on Optics, Imaging, and Instrumentation - San Diego, CA (Sunday 11 July 1993)] EUV, X-Ray, and Gamma-Ray Instrumentation for Astronomy IV - Preliminary results from the diffuse x-ray spectrometer

Sanders III, Wilton T., Edgar, Richard J., Juda, Michael, Kraushaar, William L., McCammon, Dan, Snowden, Steve L., Juda, Jiahong Z., Skinner, Mark A., Jahoda, Keith, Kelley, Richard L., Smale, A., Sta

Year:

1993

Language:

english

File:

PDF, 1.02 MB

english, 1993

74

SPIE Proceedings [SPIE International Symposium on Optical Science and Technology - San Diego, CA (Sunday 29 July 2001)] UV/EUV and Visible Space Instrumentation for Astronomy and Solar Physics - Development of the spatial heterodyne spectrometer for VUV remote sensing of the interstellar medium

Watchorn, Steve, Roesler, Fred L., Harlander, John M., Jaehnig, Kurt P., Reynolds, Ronald J., Sanders III, Wilton T., Siegmund, Oswald H. W., Fineschi, Silvano, Gummin, Mark A.

Year:

2001

Language:

english

File:

PDF, 1.04 MB

english, 2001

75

SPIE Proceedings [SPIE San Diego '92 - San Diego, CA (Sunday 19 July 1992)] EUV, X-Ray, and Gamma-Ray Instrumentation for Astronomy III - Diffuse x-ray spectrometer experiment

Sanders III, Wilton T., Edgar, Richard J., Juda, Michael, Kraushaar, William L., McCammon, Dan, Snowden, Steve L., Juda, Jiahong Z., Skinner, Mark A., Siegmund, Oswald H. W.

Year:

1992

Language:

english

File:

PDF, 617 KB

english, 1992

76

SPIE Proceedings [SPIE SPIE's 1995 International Symposium on Optical Science, Engineering, and Instrumentation - San Diego, CA (Sunday 9 July 1995)] EUV, X-Ray, and Gamma-Ray Instrumentation for Astronomy VI - Sounding rocket payload designed for investigations of the distribution and dynamics of the hot component of the interstellar medium using a field-widened spatial heterodyne spectrometer

Harlander, John M., Tran, Huan, Roesler, Fred L., Jaehnig, Kurt P., Watchorn, Steve, Sanders III, Wilton T., Reynolds, Ronald J., Siegmund, Oswald H. W., Vallerga, John V.

Year:

1995

Language:

english

File:

PDF, 492 KB

english, 1995

77

Evaluation of a short interspersed nucleotide element in the 3' untranslated region of the defective dystrophin gene of dogs with muscular dystrophy

Fletcher, Sue, Carville, Kylie S., Howell, John M., Mann, Christopher J., Wilton, Steve D.

Journal:

American Journal of Veterinary Research

Year:

2001

Language:

english

File:

PDF, 468 KB

english, 2001

78

Relation of Childhood Sexual Abuse, Intimate Partner Violence, and Depression to Risk Factors for HIV Among Black Men Who Have Sex With Men in 6 US Cities

Williams, John K., Wilton, Leo, Magnus, Manya, Wang, Lei, Wang, Jing, Dyer, Typhanye Penniman, Koblin, Beryl A., Hucks-Ortiz, Christopher, Fields, Sheldon D., Shoptaw, Steve, Stephenson, Rob, O’Cleiri

Journal:

American Journal of Public Health

Year:

2015

Language:

english

File:

PDF, 766 KB

english, 2015

79

[IEEE 2016 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW) - Chicago, IL, USA (2016.5.23-2016.5.27)] 2016 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW) - RAW Introduction and Committees

Santambrogio, Marco D., Vaidyanathan, Ramachandran, Goehringer, Diana, Wilton, Steve

Year:

2016

Language:

english

File:

PDF, 164 KB

english, 2016

80

Efficient Skipping of Single Exon Duplications in DMD Patient-Derived Cell Lines Using an Antisense Oligonucleotide Approach

Wein, Nicolas, Vulin, Adeline, Findlay, Andrew R., Gumienny, Felecia, Huang, Nianyuan, Wilton, Steve D., Flanigan, Kevin M.

Journal:

Journal of Neuromuscular Diseases

Year:

2017

Language:

english

File:

PDF, 474 KB

english, 2017

81

Gene therapy: therapeutic applications and relevance to pathology

Both, Gerald, Alexander, Ian, Fletcher, Sue, Nicolson, Tamara J., Rasko, John E.J., Wilton, Steve D., Symonds, Geoff

Journal:

Year:

2011

Language:

english

File:

PDF, 311 KB

english, 2011

82

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

Martinovich, Kelly M., Shaw, Nicole C., Kicic, Anthony, Schultz, André, Fletcher, Sue, Wilton, Steve D., Stick, Stephen M.

Journal:

Molecular and Cellular Pediatrics

Year:

2018

Language:

english

File:

PDF, 845 KB

english, 2018

83

Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript

Flynn, Loren L., Mitrpant, Chalermchai, Pitout, Ianthe L., Fletcher, Sue, Wilton, Steve D.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

84

Splice-switching as a treament for duchenne muscular dystrophy

Fletcher, Sue, Adams, Abbie M., Meloni, Penny L., Johnsen, Russell, Forrest, Sarah, Greer, Kane, Wilton, Steve D.

Journal:

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

85

Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?

Lau, Justine Y., Oliver, Brian G., Baraket, Melissa, Beckett, Emma L., Hansbro, Nicole G., Moir, Lyn M., Wilton, Steve D., Williams, Carolyn, Foster, Paul S., Hansbro, Philip M., Black, Judith L., Bur

Journal:

Year:

2010

Language:

english

File:

PDF, 2.05 MB

english, 2010

86

The FSHD Atrophic Myotube Phenotype Is Caused by DUX4 Expression

Vanderplanck, Céline, Ansseau, Eugénie, Charron, Sébastien, Stricwant, Nadia, Tassin, Alexandra, Laoudj-Chenivesse, Dalila, Wilton, Steve D., Coppée, Frédérique, Belayew, Alexandra, Chadwick, Brian P.

Journal:

Year:

2011

Language:

english

File:

PDF, 646 KB

english, 2011

87

Improved Antisense Oligonucleotide Design to Suppress Aberrant SMN2 Gene Transcript Processing: Towards a Treatment for Spinal Muscular Atrophy

Mitrpant, Chalermchai, Porensky, Paul, Zhou, Haiyan, Price, Loren, Muntoni, Francesco, Fletcher, Sue, Wilton, Steve D., Burghes, Arthur H. M., Buratti, Emanuele

Journal:

Year:

2013

Language:

english

File:

PDF, 2.99 MB

english, 2013

88

Antisense Oligonucleotide Induction of Progerin in Human Myogenic Cells

Luo, Yue-Bei, Mitrpant, Chalermchai, Adams, Abbie M., Johnsen, Russell D., Fletcher, Sue, Mastaglia, Frank L., Wilton, Steve D., Preiss, Thomas

Journal:

Year:

2014

Language:

english

File:

PDF, 1.89 MB

english, 2014

89

Inherited Retinal Disease Therapies Targeting Precursor Messenger Ribonucleic Acid

Huang, Di, Fletcher, Sue, Wilton, Steve, Palmer, Norman, McLenachan, Samuel, Mackey, David, Chen, Fred

Journal:

Year:

2017

Language:

english

File:

PDF, 2.62 MB

english, 2017

90

Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical Research

Bellgard, Matthew I., Chartres, Nigel, Watts, Gerald F., Wilton, Steve, Fletcher, Sue, Hunter, Adam, Snelling, Tom

Journal:

Frontiers in Public Health

Year:

2017

Language:

english

File:

PDF, 222 KB

english, 2017

91

Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents

Wilton, Steve, Fletcher,

Journal:

The Application of Clinical Genetics

Year:

2011

Language:

english

File:

PDF, 249 KB

english, 2011

92

Antisense Oligonucleotides Targeting Angiogenic Factors as Potential Cancer Therapeutics

Le, Bao T., Raguraman, Prithi, Kosbar, Tamer R., Fletcher, Susan, Wilton, Steve D., Veedu, Rakesh N.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2019

Language:

english

File:

PDF, 1.62 MB

english, 2019

93

Bandstab: A PCR-Based Alternative to Cloning PCR Products

Wilton, Steve D., Lim, Lynnette, Dye, Danielle, Laing, Nigel

Journal:

Year:

1997

Language:

english

File:

PDF, 44 KB

english, 1997

94

Breakpoint junction features of seven DMD deletion mutations

Keegan, Niall P., Wilton, Steve D., Fletcher, Sue

Journal:

Human Genome Variation

Year:

2019

Language:

english

File:

PDF, 1.49 MB

english, 2019

95

Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

Aung-Htut, May T., Comerford, Iain, Johnsen, Russell, Foyle, Kerrie, Fletcher, Sue, Wilton, Steve D.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 5.86 MB

english, 2019

96

Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides

Aung-Htut, May T., Comerford, Iain, Johnsen, Russell, Foyle, Kerrie, Fletcher, Sue, Wilton, Steve D.

Journal:

Scientific Reports

Year:

2019

File:

PDF, 5.86 MB

2019

97

Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides

Aung-Htut, May, McIntosh, Craig, Ham, Kristin, Pitout, Ianthe, Flynn, Loren, Greer, Kane, Fletcher, Sue, Wilton, Steve

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 1.26 MB

2019

98

Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing

McIntosh, Craig S., Aung-Htut, May Thandar, Fletcher, Sue, Wilton, Steve D.

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.95 MB

english, 2019

99

ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

Mejzini, Rita, Flynn, Loren L., Pitout, Ianthe L., Fletcher, Sue, Wilton, Steve D., Akkari, P. Anthony

Journal:

Frontiers in Neuroscience

Year:

2019

Language:

english

File:

PDF, 2.40 MB

english, 2019

100

Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing

McIntosh, Craig S., Aung-Htut, May Thandar, Fletcher, Sue, Wilton, Steve D.

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 1.95 MB

2019