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1

A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants

Mark Drost, José B.M. Zonneveld, Sandrine van Hees, Lene Juel Rasmussen, Robert M.W. Hofstra, Niels de Wind

Journal:

Year:

2012

Language:

english

File:

PDF, 425 KB

english, 2012

2

Functional analysis of HNPCC-related missense mutations in MSH2

Anne Lützen, Niels de Wind, Dubravka Georgijevic, Finn Cilius Nielsen, Lene Juel Rasmussen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2008

Language:

english

File:

PDF, 1.46 MB

english, 2008

3

The effect of two exercise modalities on skeletal muscle capillary ultrastructure in individuals with type 2 diabetes

Mortensen, Stefan Peter, Winding, Kamilla Munch, Iepsen, Ulrik Winning, Munch, Gregers Winding, Marcussen, Niels, Hellsten, Ylva, Pedersen, Bente Klarlund, Baum, Oliver

Journal:

Scandinavian Journal of Medicine & Science in Sports

Year:

2018

Language:

english

File:

PDF, 783 KB

english, 2018

4

Functional analysis helps to clarify the clinical importance of unclassified variants in DNA mismatch repair genes

Jianghua Ou, Renée C. Niessen, Anne Lützen, Rolf H. Sijmons, Jan. H. Kleibeuker, Niels de Wind, Lene Juel Rasmussen, Robert M.W. Hofstra

Journal:

Year:

2007

Language:

english

File:

PDF, 178 KB

english, 2007

5

A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1

Mark Drost, Jos é B.M. Zonneveld, Linda van Dijk, Hans Morreau, Carli M. Tops, Hans F.A. Vasen, Juul T. Wijnen, Niels de Wind

Journal:

Year:

2010

Language:

english

File:

PDF, 351 KB

english, 2010

6

Comparison of CLPP and enzyme activity assay for functional characterization of bacterial soil communities

Anne Winding, Niels Bohse Hendriksen

Journal:

Journal of Soils and Sediments

Year:

2007

Language:

english

File:

PDF, 209 KB

english, 2007

7

In memory of John Bruce Hays (1937–2014)

de Wind, Niels, Buermeyer, Andrew B., Hanawalt, Philip C.

Journal:

Year:

2014

Language:

english

File:

PDF, 138 KB

english, 2014

8

Biochemical composition of the promising live feed tropical calanoid copepod Pseudodiaptomus annandalei (Sewell 1919) cultured in Taiwanese outdoor aquaculture ponds

Rayner, Thomas Allan, Jørgensen, Niels O.G., Blanda, Elisa, Wu, Cheng-Han, Huang, Cheng-Chein, Mortensen, John, Hwang, Jiang-Shiou, Hansen, Benni Winding

Journal:

Year:

2015

Language:

english

File:

PDF, 883 KB

english, 2015

9

Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

Drost, Mark, Lützen, Anne, van Hees, Sandrine, Ferreira, Daniel, Calléja, Fabienne, Zonneveld, José B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel, de Wind, Niels

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 684 KB

english, 2013

10

ATP Increases the Affinity between MutS ATPase Domains

Lamers, Meindert H., Georgijevic, Dubravka, Lebbink, Joyce H., Winterwerp, Herrie H. K., Agianian, Bogos, de Wind, Niels, Sixma, Titia K.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 800 KB

english, 2004

11

The assessment of psychopathology among traumatized refugees: measurement invariance of the Harvard Trauma Questionnaire and the Hopkins Symptom Checklist-25 across five linguistic groups

Wind, Tim R., van der Aa, Niels, de la Rie, Simone, Knipscheer, Jeroen

Journal:

European Journal of Psychotraumatology

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

12

Adjuvant treatment for POLE proofreading domain-mutant cancers: sensitivity to radiotherapy, chemotherapy, and nucleoside analogs

Van Gool, Inge C, Rayner, Emily, Osse, Elisabeth M, Nout, Remi A, Creutzberg, Carien L, Tomlinson, Ian, Church, David N, Smit, Vincent T.H.B.M., de Wind, Niels, Bosse, Tjalling, Drost, Mark

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 14.21 MB

english, 2018

13

Testing the yield of a pilot-scale bubble column photobioreactor for cultivation of the microalga Rhodomonas salina as feed for intensive calanoid copepod cultures

Vu, Minh Thi Thuy, Jepsen, Per Meyer, Jørgensen, Niels O. G., Hansen, Benni Winding, Nielsen, Søren Laurentius

Journal:

Aquaculture Research

Year:

2018

Language:

english

File:

PDF, 530 KB

english, 2018

14

Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance

Robert M.W. Hofstra, Amanda B. Spurdle, Diana Eccles, William D. Foulkes, Niels de Wind, Nicoline Hoogerbrugge, Frans B.L. Hogervorst

Journal:

Year:

2008

Language:

english

File:

PDF, 209 KB

english, 2008

15

Assessment of functional effects of unclassified genetic variants

Fergus J. Couch, Lene Juel Rasmussen, Robert Hofstra, Alvaro N.A. Monteiro, Marc S. Greenblatt, Niels de Wind

Journal:

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

16

Quantification of the collagenolytic activity of isolated osteoclasts by enzyme-linked immunosorbent assay

Niels Taekker Foged, Jean-Marie Delaisse, Peng Hou, Henriette Lou, Takuya Sato, Bent Winding, Martin Bonde

Journal:

Journal of Bone and Mineral Research

Year:

1996

Language:

english

File:

PDF, 1.12 MB

english, 1996

17

Human breast cancer cells induce angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis

Bent Winding, Henriette Misander, Christina Sveigaard, Bente Therkildsen, Maria Jakobsen, Trine Overgaard, Merry Jo Oursler, Niels Tækker Foged

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2000

Language:

english

File:

PDF, 454 KB

english, 2000

18

Microbial community-level toxicity testing of linear alkylbenzene sulfonates in aquatic microcosms

Kristian K Brandt, Niels O.G Jørgensen, Tommy H Nielsen, Anne Winding

Journal:

FEMS Microbiology Ecology

Year:

2004

Language:

english

File:

PDF, 316 KB

english, 2004

19

10.1038/15544

Riele, Hein te, Wind, Niels de, Dekker, Marleen, Claij, Nanna, Jansen, Léon, Klink, Yvonne van, Radman, Miroslav, Riggins, Greg, Valk, Martin van der, van 't Wout, Karin

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 396 KB

english, 1999

20

10.1038/35037523

Sixma, Titia K., Lamers, Meindert H., Perrakis, Anastassis, Enzlin, Jacqueline H., Winterwerp, Herrie H. K., de Wind, Niels

Journal:

Year:

2000

Language:

english

File:

PDF, 687 KB

english, 2000

21

Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair

Lebbink, Joyce H G, Georgijevic, Dubravka, Natrajan, Ganesh, Fish, Alexander, Winterwerp, Herrie H K, Sixma, Titia K, de Wind, Niels

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 418 KB

english, 2006

22

Evidence of a Correlation of Estrogen Receptor Level and Avian Osteoclast Estrogen Responsiveness

Larry Pederson, Matthew Kremer, Niels Tækker Foged, Bent Winding, Candace Ritchie, Lorraine A. Fitzpatrick, Merry Jo Oursler

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 590 KB

english, 1997

23

Estradiol Enhances Osteolytic Lesions in Mice Inoculated with Human Estrogen Receptor-Negative MDA-231 Breast Cancer Cellsin vivo

Bent Winding, Henriette Misander, Pernille Høegh-Andersen, Nils Brünner, Niels Tækker Foged

Journal:

Breast Cancer Research and Treatment

Year:

2003

Language:

english

File:

PDF, 327 KB

english, 2003

24

Mutagenesis and Characterization of a 41-Kilobase-Pair Region of the Pseudorabies Virus Genome: Transcription Map. Search for Virulence Genes, and Comparison with Homologs of Herpes Simplex Virus Type 1

Niels de Wind, Ben P.H. Peeters, Alice Zijderveld, Arno L.J. Gielkens, Anton J.M. Berns, Tjeerd S. Kimman

Journal:

Year:

1994

File:

PDF, 437 KB

1994

25

Inactivation of Glycoprotein gE and Thymidine Kinase or the US3-Encoded Protein Kinase Synergistically Decreases in Vivo Replication of Pseudorabies Virus and the Induction of Protective Immunity

Tjeerd G. Kimman, Niels De Wind, Tiny De Bruin, Yolanda De Visser, John Voermans

Journal:

Year:

1994

File:

PDF, 502 KB

1994

26

Second messengers and ion channels in acetylcholine-induced chloride secretion in hen trachea

Bent Winding, Helle Winding, Niels Bindslev

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

27

Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

Giel Hendriks, Fabienne Calléja, Ahmad Besaratinia, Harry Vrieling, Gerd P. Pfeifer, Leon H.F. Mullenders, Jacob G. Jansen, Niels de Wind

Journal:

Current Biology

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

28

Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells

Giel Hendriks, Fabienne Calléja, Harry Vrieling, Leon H.F. Mullenders, Jacob G. Jansen, Niels de Wind

Journal:

Year:

2008

Language:

english

File:

PDF, 800 KB

english, 2008

29

Mammalian polymerase ζ is essential for post-replication repair of UV-induced DNA lesions

Jacob G. Jansen, Anastasia Tsaalbi-Shtylik, Giel Hendriks, Johan Verspuy, Himabindu Gali, Lajos Haracska, Niels de Wind

Journal:

Year:

2009

Language:

english

File:

PDF, 806 KB

english, 2009

30

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance

Peter H.L. Krijger, Paul C.M. van den Berk, Niek Wit, Petra Langerak, Jacob G. Jansen, Claude-Agnès Reynaud, Niels de Wind, Heinz Jacobs

Journal:

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

31

The Rev1 translesion synthesis polymerase has multiple distinct DNA binding modes

Frederik H. de Groote, Jacob G. Jansen, Yuji Masuda, Dipen M. Shah, Kenji Kamiya, Niels de Wind, Gregg Siegal

Journal:

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

32

Temporally distinct translesion synthesis pathways for ultraviolet light-induced photoproducts in the mammalian genome

Piya Temviriyanukul, Sandrine van Hees-Stuivenberg, Frédéric Delbos, Heinz Jacobs, Niels de Wind, Jacob G. Jansen

Journal:

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

33

Spontaneous and mutagen-induced loss of DNA mismatch repair in Msh2-heterozygous mammalian cells

Viola Borgdorff, Sandrine van Hees-Stuivenberg, Caro M. Meijers, Niels de Wind

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

34

Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides

Marleen Dekker, Sandra de Vries, Marieke Aarts, Robert Dekker, Conny Brouwers, Oliver Wiebenga, Niels de Wind, Erika Cantelli, Roberto Tonelli, Hein te Riele

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 735 KB

english, 2011

35

In situ and laboratory growth by a population of blue mussel larvae (Mytilus edulis L.) from a Danish embayment, Knebel Vig

Frank Leck Fotel, Niels Jacob Jensen, Louise Wittrup, Benni Winding Hansen

Journal:

Journal of Experimental Marine Biology and Ecology

Year:

1999

Language:

english

File:

PDF, 620 KB

english, 1999

36

Mismatch repair: praying for genome stability

Niels de Wind, John B. Hays

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

37

Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future

Lene Juel Rasmussen, Christopher D. Heinen, Brigitte Royer-Pokora, Mark Drost, Sean Tavtigian, Robert M.W. Hofstra, Niels de Wind

Journal:

Year:

2012

Language:

english

File:

PDF, 282 KB

english, 2012

38

Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes

Marijke van Oosten, Gerdine J Stout, Claude Backendorf, Heggert Rebel, Niels de Wind, Firouz Darroudi, Henk J van Kranen, Frank R de Gruijl, Leon HF Mullenders

Journal:

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

39

DNA mismatch repair mediates protection from mutagenesis induced by short-wave ultraviolet light

Viola Borgdorff, Bea Pauw, Sandrine van Hees-Stuivenberg, Niels de Wind

Journal:

Year:

2006

Language:

english

File:

PDF, 409 KB

english, 2006

40

Send in the Clamps: Control of DNA Translesion Synthesis in Eukaryotes

Jacob G. Jansen, Maria I. Fousteri, Niels de Wind

Journal:

Year:

2007

Language:

english

File:

PDF, 568 KB

english, 2007

41

Biological functions of translesion synthesis proteins in vertebrates

Jacob G. Jansen, Niels de Wind

Journal:

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

42

Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway

Krijger, Peter HL, Tsaalbi-Shtylik, Anastasia, Wit, Niek, van den Berk, Paul Cornelius Maria, de Wind, Niels, Jacobs, Heinz

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 568 KB

english, 2013

43

Myelin alters the inflammatory phenotype of macrophages by activating PPARs

Bogie, Jeroen FJ, Jorissen, Winde, Mailleux, Jo, Nijland, Philip G, Zelcer, Noam, Vanmierlo, Tim, Van Horssen, Jack, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome JA

Journal:

Acta Neuropathologica Communications

Year:

2013

Language:

english

File:

PDF, 2.97 MB

english, 2013

44

Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2 : Use of potential alternative start sites and implications for predicting variant pathogenicity

Parsons, Michael T., Whiley, Phillip J., Beesley, Jonathan, Drost, Mark, de Wind, Niels, Thompson, Bryony A., Marquart, Louise, Hopper, John L., Jenkins, Mark A., Brown, Melissa A., Tucker, Kathy, War

Journal:

Molecular Carcinogenesis

Year:

2015

Language:

english

File:

PDF, 321 KB

english, 2015

45

In memory of John Bruce Hays (1937–2014)

de Wind, Niels, Buermeyer, Andrew B., Hanawalt, Philip C.

Journal:

Year:

2014

Language:

english

File:

PDF, 182 KB

english, 2014

46

Inactivation of DNA Mismatch Repair by Variants of Uncertain Significance in the PMS2 Gene

Drost, Mark, Koppejan, Hester, de Wind, Niels

Journal:

Year:

2013

Language:

english

File:

PDF, 416 KB

english, 2013

47

Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome

Oberbeck, Nina, Langevin, Frédéric, King, Gareth, de Wind, Niels, Crossan, Gerry P., Patel, Ketan J.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.68 MB

english, 2014

48

Response to: Design of a Core Classification Process for DNA Mismatch Repair Variations of A Priori Unknown Functional Significance

Rasmussen, Lene Juel, Heinen, Christopher D., Royer-Pokora, Brigitte, Drost, Mark, Tavtigian, Sean, Hofstra, Robert M.W., de Wind, Niels

Journal:

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

49

Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein

Dominguez-Valentin, Mev, Drost, Mark, Therkildsen, Christina, Rambech, Eva, Ehrencrona, Hans, Angleys, Maria, Lau Hansen, Thomas, de Wind, Niels, Nilbert, Mef, Juel Rasmussen, Lene

Journal:

Molecular Genetics & Genomic Medicine

Year:

2014

Language:

english

File:

PDF, 417 KB

english, 2014

50

Site-directed mutagenesis of the Escherichia coli chromosome near oriC : identification and characterization of asnC , a regulatory element in E. coli asparagine metabolism

Wind, Niels de, Jong, Marian de, Meijer, Michiel, Stuitje, Antoine Raymond

Journal:

Nucleic Acids Research

Year:

1985

Language:

english

File:

PDF, 662 KB

english, 1985