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51

A novel EGFR nonsense mutation in a non-small-cell lung cancer (NSCLC) patient who did not derive any clinical benefit with combination chemotherapy and erlotinib

Ramón González Manzano, Elena Martínez Navarro, Elena Eugenieva, Francisco José Fernández Morejón, José Farré, Antonio Brugarolas

Journal:

Clinical and Translational Oncology

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

52

Cytoreductive surgery and perioperative intraperitoneal chemotherapy in patients with peritoneal carcinomatosis of colonic origin: outcomes after 7 years’ experience of a new centre for peritoneal surface malignancies

Pedro Bretcha-Boix, Jose Farré-Alegre, Manuel Sureda, Carlos Dussan, Juan José Pérez Ruixo, Antonio Brugarolas Masllorens

Journal:

Clinical and Translational Oncology

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

53

Epidermal growth factor receptor (EGFR) mutations in a series of non-small-cell lung cancer (NSCLC) patients and response rate to EGFR-specific tyrosine kinase inhibitors (TKIs)

Elena María Martínez-Navarro, Joseba Rebollo, Ramón González-Manzano, Manuel Sureda, Elena Evgenyeva, Belén Valenzuela, Francisco José Fernández, Jerónimo Forteza, Antonio Brugarolas

Journal:

Clinical and Translational Oncology

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

54

Effect of grapefruit juice on the pharmacokinetics of docetaxel in cancer patients: a case report

Belén Valenzuela, Joseba Rebollo, Tania Pérez, Antonio Brugarolas, Juan José Pérez-Ruixo

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 505 KB

english, 2011

55

Radiation-induced cell cycle arrest compromised by p21 deficiency

Brugarolas, James, Chandrasekaran, Chitra, Gordon, Jeffrey I., Beach, David, Jacks, Tyler, Hannon, Gregory J.

Journal:

Year:

1995

File:

PDF, 1.47 MB

1995

56

Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality

de Oca Luna, Roberto Montes, Amelse, Lisa L., Chavez-Reyes, Arturo, Evans, Susan C., Brugarolas, James, Jacks, Tyler, Lozano, Guillermina

Journal:

Nature Genetics

Year:

1997

File:

PDF, 334 KB

1997

57

Double indemnity: p53, BRCA and cancer

Brugarolas, James, Jacks, Tyler

Journal:

Nature Medicine

Year:

1997

File:

PDF, 286 KB

1997

58

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Majumder, Pradip K, Febbo, Phillip G, Bikoff, Rachel, Berger, Raanan, Xue, Qi, McMahon, Louis M, Manola, Judith, Brugarolas, James, McDonnell, Timothy J, Golub, Todd R

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 3.29 MB

english, 2004

59

Multiple cycles of dose-intensive chemotherapy with repeated stem cell support as induction treatment in metastatic breast cancer: a feasibility study

García-Rayo, S, Pérez-Calvo, J, Martín-Algarra, S, Martínez-Monge, R, Fernández-Hidalgo, O, Subirá, L, Martínez-Aguillo, M, Rebollo, J, Azinovic, I, Brugarolas, A

Journal:

Bone Marrow Transplantation

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

60

Role of fibre and fruit in the Mediterranean diet to protect against myocardial infarction: a case–control study in Spain

Martínez-González, M A, Fernández-Jarne, E, Martínez-Losa, E, Prado-Santamaría, M, Brugarolas-Brufau, C, Serrano-Martinez, M

Journal:

European Journal of Clinical Nutrition

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

61

Relationship between pharmacokinetic parameters of gentamicin and patient characteristics and/or clinical data in patients with solid organ tumours

A. Ortega, A. Aldaz, J. Giráldez, A Brugarolas

Journal:

International Journal of Clinical Pharmacy

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

62

Docetaxel Plus Vinorelbine as Salvage Chemotherapy in Advanced Breast Cancer: A Phase II Study

Javier Rodríguez, Emiliano Calvo, J. Cortes, Marta Santisteban, J. Perez-Calvo, Rafael Martínez-Monge, Antonio Brugarolas, Óscar Fernández-Hidalgo

Journal:

Breast Cancer Research and Treatment

Year:

2002

Language:

english

File:

PDF, 101 KB

english, 2002

63

Erratum to: Pharmacokinetic and Pharmacodynamic Analysis of Hyperthermic Intraperitoneal Oxaliplatin-Induced Neutropenia in Subjects with Peritoneal Carcinomatosis

Belén Valenzuela, Ricardo Nalda-Molina, Pere Bretcha-Boix, Vanesa Escudero-Ortíz, Maria José Duart, Vicente Carbonell, Manuel Sureda, José Pascual Rebollo, Josep Farré, Antonio Brugarolas, Juan Pérez-

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

64

Pharmacokinetic and Pharmacodynamic Analysis of Hyperthermic Intraperitoneal Oxaliplatin-Induced Neutropenia in Subjects with Peritoneal Carcinomatosis

Belén Valenzuela, Ricardo Nalda-Molina, Pere Bretcha-Boix, Vanesa Escudero-Ortíz, Maria José Duart, Vicente Carbonell, Manuel Sureda, José Pascual Rebollo, Josep Farré, Antonio Brugarolas, Juan José P

Journal:

The AAPS Journal

Year:

2011

Language:

english

File:

PDF, 701 KB

english, 2011

65

State of the Science: An Update on Renal Cell Carcinoma

Jonasch, E., Futreal, P. A., Davis, I. J., Bailey, S. T., Kim, W. Y., Brugarolas, J., Giaccia, A. J., Kurban, G., Pause, A., Frydman, J., Zurita, A. J., Rini, B. I., Sharma, P., Atkins, M. B., Walker,

Journal:

Molecular Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

66

[IEEE 2012 IEEE Aerospace Conference - Big Sky, MT (2012.03.3-2012.03.10)] 2012 IEEE Aerospace Conference - System verification of MSL Skycrane using an integrated ADAMS simulation

White, C., Antoun, G., Brugarolas, P., Shyh-Shiuh Lih,, Chia-Yen Peng,, Linh Phan,, Martin, A. S., Sell, S., Singh, G.

Year:

2012

Language:

english

File:

PDF, 1019 KB

english, 2012

67

Type of alcoholic beverage and first acute myocardial infarction: A case-control study in a mediterranean country

E. Fernández-Jarne, E. Martínez-Losa, M. Serrano-Martínez, M. Prado-Santamaría, C Brugarolas-Brufau, Prof. M. A. Martínez-González

Journal:

Clinical Cardiology

Year:

2003

Language:

english

File:

PDF, 44 KB

english, 2003

68

Phase II clinical trial of DDMP (2,4-diamino-5-(3′,4′-dichlorophenyl)-6-methylpyrimidine) and folinic acid (CF) in solid tumors

Robert Jager, Antonio Brugarolas, Mogens Hansen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1981

Language:

english

File:

PDF, 290 KB

english, 1981

69

Phase II study of anhydro-ara-5-fluorocytidine in adenocarcinoma of gastrointestinal tract, epidermoid carcinoma of lung, head and neck, breast carcinoma and small cell anaplastic carcinoma of lung: A study report of the E.O.R.T.C. early clinical trial cooperative group

P. Alberto, M. Rozencweig, D. Gangji, A. Brugarolas, F. Cavalli, P. Siegenthaler, H.H. Hansen, R. Sylvester

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 527 KB

english, 1965

70

Vincristine (NSC 67574) in non-small cell bronchogenic carcinoma. Results of a phase II clinical study

A. Brugarolas, A.J. Lacave, A. Ribas, M.T.Garcia Miralles

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 3.52 MB

english, 1965

71

E.O.R.T.C. phase II study of cisplatin in cyvadic-resistant soft tissue sarcoma

Vivien H.C. Bramwell, A. Brugarolas, H.T. Mouridsen, Françoise Cheix, R. De Jager, A.T. Van Oosterom, C.P. Vendrik, H.M. Pinedo, R. Sylvester, Marlene De Pauw

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 262 KB

english, 1965

72

Results of two sequential chemotherapy studies in WHO Types I, III and IV lung cancer: Cyclophosphamide-5-fluorouracil (CF) and cyclophosphamide-5-fluorouracil-adriamycin (CAF)

A. Brugarolas, A.J. Lacave, A. Ribas, J.M. Buesa, M.T.Garcia Miralles

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 360 KB

english, 1965

73

Dianhydrogalactitol (NSC-132313): Phase II study in solid tumors: A Report of the E.O.R.T.C. Early Clinical Trial Cooperative Group

R. De Jager, A. Brugarolas, H. Hansen, F. Cavalli, H. Ryssel, P. Siegenthaler, A. Clarysse, J. Renard, Y. Kenis, P. Alberto

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 315 KB

english, 1965

74

Clinical study of vincristine in adenocarcinoma of the lung: A study of the Early-Clinical-Trial Group of the E.O.R.T.C.

A. Brugarolas, H.H. Hansen, P. Siegenthaler

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 89 KB

english, 1965

75

Phase II study of diamino-dichlorophenyl-methylpyrimidine (DDMP) with folinic acid (CF) protection and rescue

Pierre Alberto, Antonio Brugarolas, Heine H. Hansen, Franco Cavalli, Olbjørn Klepp, Josette Renard

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 552 KB

english, 1965

76

Factores influyentes en el tiempo hasta la progresión bioquímica después de prostatectomía radical

J. Barba, X. Brugarolas, E. Tolosa, A. Rincón, L. Romero, D. Rosell, J.E. Robles, J.J. Zudaire, J.M. Berian, J.I. Pascual

Journal:

Actas Urológicas Españolas (Spanish Edition)

Year:

2011

File:

PDF, 113 KB

2011

77

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

James Brugarolas, William G Kaelin Jr.

Journal:

Year:

2004

Language:

english

File:

PDF, 109 KB

english, 2004

78

Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type 2

Lisa Kinch, Nick V. Grishin, James Brugarolas

Journal:

Year:

2011

Language:

english

File:

PDF, 341 KB

english, 2011

79

The Impact of Targeted Molecular Therapies on the Level of Renal Cell Carcinoma Vena Caval Tumor Thrombus

Nicholas G. Cost, Scott E. Delacroix Jr., Joshua P. Sleeper, Paul J. Smith, Ramy F. Youssef, Brian F. Chapin, Jose A. Karam, Stephen Culp, E. Jason Abel, James Brugarolas, Ganesh V. Raj, Arthur I. Sag

Journal:

European Urology

Year:

2011

Language:

english

File:

PDF, 403 KB

english, 2011

80

Foco pulmonar facticio con 18F-FDG: posible error en la interpretación de la PET-CT

M.C. Redal Peña, F.J. Pena Pardo, J. Muñoz Iglesias, A. Crespo-Jara, J. Rebollo, A. Brugarolas Masllorens

Journal:

Revista Española de Medicina Nuclear

Year:

2011

File:

PDF, 386 KB

2011

81

HDAC, a key to pRb tumour suppression?

L Attardi, J Brugarolas, A Heinrichs

Journal:

Trends in Cell Biology

Year:

1998

Language:

english

File:

PDF, 34 KB

english, 1998

82

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

James B Brugarolas, Francisca Vazquez, Archana Reddy, William R Sellers, William G Kaelin Jr.

Journal:

Year:

2003

Language:

english

File:

PDF, 662 KB

english, 2003

83

The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis

Brugarolas, P., Movahedzadeh, F., Wang, Y., Zhang, N., Bartek, I. L., Gao, Y. N., Voskuil, M. I., Franzblau, S. G., He, C.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.14 MB

english, 2012

84

Avoiding Cracks in Nanoparticle Films

Prosser, Jacob H., Brugarolas, Teresa, Lee, Steven, Nolte, Adam J., Lee, Daeyeon

Journal:

Year:

2012

Language:

english

File:

PDF, 2.03 MB

english, 2012

85

TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy

Peña-Llopis, Samuel, Brugarolas, James

Journal:

Year:

2011

Language:

english

File:

PDF, 746 KB

english, 2011

86

To what extent are the effects of diet on coronary heart disease lipid-mediated?

M Serrano-Martinez, E Martinez-Losa, M Prado-Santamaria, C Brugarolas-Brufau, E Fernandez-Jarne, M.A Martinez-Gonzalez

Journal:

International Journal of Cardiology

Year:

2004

Language:

english

File:

PDF, 84 KB

english, 2004

87

VID-02.03: Xenograft interposition in female urethral diverticulum surgery

J.E. Robles, J.P. Rioja, A. Saiz, X. Brugarolas, A. Rincón, E. Tolosa, D. Rosell, J.J. Zudaire, J.M. Berian

Journal:

Year:

2007

Language:

english

File:

PDF, 57 KB

english, 2007

88

Towards a genomic-based diagnosis

James Brugarolas, Barton F Haynes, Joseph R Nevins

Journal:

Year:

2001

Language:

english

File:

PDF, 53 KB

english, 2001

89

Using “rationally designed drugs” rationally

Jim Brugarolas, Jeffrey W Clark, Bruce Chabner

Journal:

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

90

Analysis of telomerase activity in physiological and pathological endometrial tissues

E. Jiménez, J. García-Foncillas, M. Guzmán, E. Andión, M. Huarriz, I. Okroujnov, T. Errasti, M. Jurado, J. Schneider, A. Brugarolas

Journal:

European Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 227 KB

english, 1999

91

Hypermethylation of the hMLH1 promoter region in high-grade gliomas

E. Andión, J. García-Foncillas, E. Salgado, E. Jiménez, M. Huarriz, M. Guzmán, I. Okroujnov, V. Vanaclocha, G. Villares, A. Brugarolas

Journal:

European Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

92

PET-FDG in the Preoperative Evaluation of Non Small Cell Lung Cancer (NSCLC) Staging: A Comparison with CT Scanning and MRI

J.A. Richter, W. Torre, M.J. Garcı́a, J.M. Aramendia, M. Giménez, A. Brugarolas

Journal:

Clinical Positron Imaging

Year:

1998

Language:

english

File:

PDF, 58 KB

english, 1998

93

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Hasan, Maroof, Koch, James, Rakheja, Dinesh, Pattnaik, Asit K, Brugarolas, James, Dozmorov, Igor, Levine, Beth, Wakeland, Edward K, Lee-Kirsch, Min Ae, Yan, Nan

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

94

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

Mata, Miguel A, Satterly, Neal, Versteeg, Gijs A, Frantz, Doug, Wei, Shuguang, Williams, Noelle, Schmolke, Mirco, Peña-Llopis, Samuel, Brugarolas, James, Forst, Christian V, White, Michael A, García-S

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

95

Space-quality data from balloon-borne telescopes: The High Altitude Lensing Observatory (HALO)

Jason Rhodes, Benjamin Dobke, Jeffrey Booth, Richard Massey, Kurt Liewer, Roger Smith, Adam Amara, Jack Aldrich, Joel Berge, Naidu Bezawada, Paul Brugarolas, Paul Clark, Cornelis M. Dubbeldam, Richard

Journal:

Astroparticle Physics

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

96

Tratamiento regional del sarcoma y melanoma localmente avanzado de la extremidad mediante la perfusión aislada con tumor necrosis factor α y melfalan asociada a hipertermia

José Farre Alegre, Maritza Duarte, Manuel Sureda González, Pere Bretcha Boix, Carlos Dussan, Antonio Ballester, Aurora Crespo, Antonio Brugarolas Masllorens

Journal:

Cirugía Española

Year:

2012

File:

PDF, 1.95 MB

2012

97

Metabolism of Kidney Cancer: From the Lab to Clinical Practice

Sunil Sudarshan, Jose A. Karam, James Brugarolas, R. Houston Thompson, Robert Uzzo, Brian Rini, Vitaly Margulis, Jean-Jacques Patard, Bernard Escudier, W. Marston Linehan

Journal:

European Urology

Year:

2013

Language:

english

File:

PDF, 262 KB

english, 2013

98

Lung hot spot as pitfall in PET-CT interpretation: focal lung uptake of 18F-fluorodeoxyglucose

M.C. Redal Peña, F.J. Pena Pardo, J. Muñoz Iglesias, A. Crespo-Jara, J. Rebollo, A. Brugarolas Masllorens

Journal:

Revista Española de Medicina Nuclear (English Edition)

Year:

2011

Language:

english

File:

PDF, 385 KB

english, 2011

99

500 - Evidence of circulating tumor cells of Ewing's sarcoma is associated with higher incidence of local relapse and metastatic spread

J. García-Foncillas, P. Philip, M.S. Huárriz, M.J. Martínez, M.G. Guzmán, A. Brugarolas

Journal:

European Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 391 KB

english, 1997

100

39 EPITHELIAL CELL ADHESION MOLECULE (EPCAM) EXPRESSION IN RENAL CELL CARCINOMAS (RCC). A TISSUE MICROARRAY STUDY

J. Rioja, A. Panizo, J.J. Sola, X. Brugarolas, A. Saiz, J. Echeveste, M.D. Lozano, J.E. Robles, J.J. Zudaire, J.M. Berian, F.J. Pardo

Journal:

European Urology Supplements

Year:

2007

Language:

english

File:

PDF, 317 KB

english, 2007

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