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51

Modified plasma clearance technique using nonradioactive iothalamate for measuring GFR

Isaka, Yoshitaka, Fujiwara, Yoshihiro, Yamamoto, Shigeo, Ochi, Satoshi, Shin, SungHyo, Inoue, Toru, Tagawa, Kunio, Kamada, Takenobu, Ueda, Naohiko

Journal:

Kidney International

Year:

1992

Language:

english

File:

PDF, 390 KB

english, 1992

52

Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis

Akagi, Yoshitaka, Isaka, Yoshitaka, Arai, Makoto, Kaneko, Tetsuya, Takenaka, Masaru, Moriyama, Toshiki, Kaneda, Yasufumi, Ando, Akio, Orita, Yoshimasa, Kamada, Takenobu

Journal:

Kidney International

Year:

1996

File:

PDF, 5.41 MB

1996

53

Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and β-actin/β-globin gene in glomerular epithelial cells in vivo

Akagi, Yoshitaka, Isaka, Yoshitaka, Akagi, Akiko, Ikawa, Masahito, Takenaka, Masaru, Moriyama, Toshiki, Yamauchi, Atsushi, Horio, Masaru, Ueda, Naohiko, Okabe, Masaru

Journal:

Kidney International

Year:

1997

Language:

english

File:

PDF, 550 KB

english, 1997

54

HGF gene transfer increases kidney graft survival

ISAKA, YOSHITAKA, YAMADA, KAZUHIKO

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 43 KB

english, 2005

55

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

Kawagoe, Tatsukata, Takeuchi, Osamu, Takabatake, Yoshitsugu, Kato, Hiroki, Isaka, Yoshitaka, Tsujimura, Tohru, Akira, Shizuo

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 585 KB

english, 2009

56

Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

Isaka, Yoshitaka, Brees, Douglas K., Ikegaya, Kazuko, Kaneda, Yasufumi, Imai, Enyu, Noble, Nancy A., Border, Wayne A.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 732 KB

1996

57

Evidence for Direct Association of Vpr and Matrix Protein p17 within the HIV-1 Virion

AKIHIKO SATO, JUN YOSHIMOTO, YOSHITAKA ISAKA, SHIGERU MIKI, AKEMI SUYAMA, AKIO ADACHI, MASANORI HAYAMI, TAMIO FUJIWARA, OSAMU YOSHIE

Journal:

Year:

1996

Language:

english

File:

PDF, 157 KB

english, 1996

58

Small Amino Acid Changes in the V3 Loop of Human Immunodeficiency Virus Type 2 Determines the Coreceptor Usage for CXCR4 and CCR5

Yoshitaka Isaka, Akihiko Sato, Shigeru Miki, Shinobu Kawauchi, Hitoshi Sakaida, Toshiyuki Hori, Takashi Uchiyama, Akio Adachi, Masanori Hayami, Tamio Fujiwara, Osamu Yoshie

Journal:

Year:

1999

Language:

english

File:

PDF, 202 KB

english, 1999

59

In Vivo Gene Transfer of Hepatocyte Growth Factor to Skeletal Muscle Prevents Changes in Rat Kidneys After 5/6 Nephrectomy

Toshiyuki Tanaka, Naotsugu Ichimaru, Shiro Takahara, Koji Yazawa, Motoaki Hatori, Kazuhiro Suzuki, Yoshitaka Isaka, Toshiki Moriyama, Enyu Imai, Haruhito Azuma, Toshikazu Nakamura, Akihiko Okuyama, Hi

Journal:

American Journal of Transplantation

Year:

2002

Language:

english

File:

PDF, 384 KB

english, 2002

60

Self-reported Sleep Duration and Prediction of Proteinuria: A Retrospective Cohort Study

Ryohei Yamamoto, Yasuyuki Nagasawa, Hirotsugu Iwatani, Maki Shinzawa, Yoshitsugu Obi, Junya Teranishi, Toshihiro Ishigami, Keiko Yamauchi-Takihara, Makoto Nishida, Hiromi Rakugi, Yoshitaka Isaka, Tosh

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 518 KB

english, 2012

61

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

Atsushi Takahashi, Tomonori Kimura, Yoshitsugu Takabatake, Tomoko Namba, Junya Kaimori, Harumi Kitamura, Isao Matsui, Fumio Niimura, Taiji Matsusaka, Naonobu Fujita, Tamotsu Yoshimori, Yoshitaka Isaka

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 1.89 MB

english, 2012

62

Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis

Ryoichi Imamura, Yoshitaka Isaka, Naotsugu Ichimaru, Shiro Takahara, Akihiko Okuyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 901 KB

english, 2007

63

HGF–MSP chimera protects kidneys from ischemia–reperfusion injury

Feng Xue, Yoshitaka Isaka, Terumi Takahara, Ryoichi Imamura, Chigure Suzuki, Naotsugu Ichimaru, Paolo Michieli, Shiro Takahara

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 421 KB

english, 2007

64

Chemically modified siRNA prolonged RNA interference in renal disease

Yoshitsugu Takabatake, Yoshitaka Isaka, Masayuki Mizui, Hiroshi Kawachi, Shiro Takahara, Enyu Imai

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 922 KB

english, 2007

65

Participation of autophagy in renal ischemia/reperfusion injury

Chigure Suzuki, Yoshitaka Isaka, Yoshitsugu Takabatake, Hirotaka Tanaka, Masato Koike, Masahiro Shibata, Yasuo Uchiyama, Shiro Takahara, Enyu Imai

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

66

Microarray analysis of tonsils in immunoglobulin A nephropathy patients

Kenichiro Iio, Yasuyuki Nagasawa, Hirotsugu Iwatani, Ryohei Yamamoto, Arata Horii, Daisuke Okuzaki, Yoshiyuki Furumatsu, Hidenori Inohara, Hiroshi Nojima, Enyu Imai, Yoshitaka Isaka, Hiromi Rakugi

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 323 KB

english, 2010

67

Serum NTX is a practical marker for assessing antiresorptive therapy for glucocorticoid treated patients with chronic kidney disease

Takayuki Hamano, Naohiko Fujii, Yasuyuki Nagasawa, Yoshitaka Isaka, Toshiki Moriyama, Noriyuki Okada, Enyu Imai, Masaru Horio, Takahito Ito

Journal:

Year:

2006

Language:

english

File:

PDF, 454 KB

english, 2006

68

Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients

Kodo Tomida, Takayuki Hamano, Satoshi Mikami, Naohiko Fujii, Noriyuki Okada, Isao Matsui, Yasuyuki Nagasawa, Toshiki Moriyama, Takahito Ito, Enyu Imai, Yoshitaka Isaka, Hiromi Rakugi

Journal:

Year:

2009

Language:

english

File:

PDF, 410 KB

english, 2009

69

Usefulness of bone resorption markers in hemodialysis patients

Takayuki Hamano, Kodo Tomida, Satoshi Mikami, Isao Matsui, Naohiko Fujii, Enyu Imai, Hiromi Rakugi, Yoshitaka Isaka

Journal:

Year:

2009

Language:

english

File:

PDF, 471 KB

english, 2009

70

The impact of diabetes mellitus on vitamin D metabolism in predialysis patients

Hirotaka Tanaka, Takayuki Hamano, Naohiko Fujii, Kodo Tomida, Isao Matsui, Satoshi Mikami, Yasuyuki Nagasawa, Takahito Ito, Toshiki Moriyama, Masaru Horio, Enyu Imai, Yoshitaka Isaka, Hiromi Rakugi

Journal:

Year:

2009

Language:

english

File:

PDF, 560 KB

english, 2009

71

Foxp3-expressing Regulatory T Cells Expanded With CD28 Superagonist Antibody Can Prevent Rat Cardiac Allograft Rejection

Yusuke Kitazawa, Masayuki Fujino, Takatoshi Sakai, Haruhito Azuma, Hiromitsu Kimura, Yoshitaka Isaka, Shiro Takahara, Thomas Hünig, Ryo Abe, Xiao-Kang Li

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

72

Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production

Lin Xie, Xiao-Kang Li, Naoko Funeshima-Fuji, Hiromitsu Kimura, Yoh Matsumoto, Yoshitaka Isaka, Shiro Takahara

Journal:

International Immunopharmacology

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

73

Expression and purification of untagged full-length HCV NS5B RNA-dependent RNA polymerase

Q May Wang, Robert B Johnson, Dayue Chen, Vincent J.-P Lévêque, Jianxin Ren, Michelle A Hockman, Kenji Abe, Tessho Hachisu, Yutaka Kondo, Yoshitaka Isaka, Akihiko Sato, Tamio Fujiwara

Journal:

Protein Expression and Purification

Year:

2004

Language:

english

File:

PDF, 660 KB

english, 2004

74

Antisense Oligonucleotides Against Thrombospondin-1 Inhibit Activation of TGF-β in Fibrotic Renal Disease in the Rat in Vivo

Christoph Daniel, Yoshitugu Takabatake, Masayuki Mizui, Yoshitaka Isaka, Hiroshi Kawashi, Harald Rupprecht, Enyu Imai, Christian Hugo

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 555 KB

english, 2003

75

Carbamylated Erythropoietin Ameliorates Cyclosporine Nephropathy Without Stimulating Erythropoiesis

Abe, Toyofumi, Isaka, Yoshitaka, Imamura, Ryoichi, Kakuta, Yoichi, Okumi, Masayoshi, Yazawa, Koji, Ichimaru, Naotsugu, Tsuda, Hidetoshi, Nonomura, Norio, Takahara, Shiro, Okuyama, Akihiko

Journal:

Cell Transplantation

Year:

2012

Language:

english

File:

PDF, 9.00 MB

english, 2012

76

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Imamura, Ryoichi, Isaka, Yoshitaka, Sandoval, Ruben M., Ichimaru, Naotsugu, Abe, Toyofumi, Okumi, Masayoshi, Yazawa, Koji, Kitamura, Harumi, Kaimori, Jyunya, Nonomura, Norio, Rakugi, Hiromi, Molitoris

Journal:

Clinical and Experimental Nephrology

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

77

Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy

Omori, Hiroki, Kawada, Noritaka, Inoue, Kazunori, Ueda, Yoshiyasu, Yamamoto, Ryohei, Matsui, Isao, Kaimori, Jyunya, Takabatake, Yoshitsugu, Moriyama, Toshiki, Isaka, Yoshitaka, Rakugi, Hiromi

Journal:

Clinical and Experimental Nephrology

Year:

2012

Language:

english

File:

PDF, 456 KB

english, 2012

78

Febuxostat suppressed renal ischemia–reperfusion injury via reduced oxidative stress

Hidetoshi Tsuda, Noritaka Kawada, Jun-ya Kaimori, Harumi Kitamura, Toshiki Moriyama, Hiromi Rakugi, Shiro Takahara, Yoshitaka Isaka

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 993 KB

english, 2012

79

Quantitative change of IgA hinge O-glycan composition is a novel marker of therapeutic responses of IgA nephropathy

Hirotsugu Iwatani, Takahiro Inoue, Yoshinao Wada, Yasuyuki Nagasawa, Ryohei Yamamoto, Hideki Iijima, Tetsuo Takehara, Enyu Imai, Hiromi Rakugi, Yoshitaka Isaka

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

80

Reply to “FGF23 adds value to risk prediction in patients with chronic kidney disease”

Takayuki Hamano, Chikako Nakano, Naohiko Fujii, Isao Matsui, Kodo Tomida, Satoshi Mikami, Kazunori Inoue, Yoshitsugu Obi, Akihiro Shimomura, Noriyuki Okada, Hiromi Rakugi, Yoshitaka Isaka, Yoshiharu T

Journal:

Year:

2012

Language:

english

File:

PDF, 108 KB

english, 2012

81

Dialysis vintage and parathyroid hormone level, not fibroblast growth factor-23, determines chronic-phase phosphate wasting after renal transplantation

Kodo Tomida, Takayuki Hamano, Naotsugu Ichimaru, Naohiko Fujii, Isao Matsui, Norio Nonomura, Yoshiharu Tsubakihara, Hiromi Rakugi, Shiro Takahara, Yoshitaka Isaka

Journal:

Year:

2012

Language:

english

File:

PDF, 696 KB

english, 2012

82

Oral active vitamin d therapy as a potential chemoprevention against post-transplant malignancy

Yoshitsugu Obi, Naotsugu Ichimaru, Isao Matsui, Takayuki Hamano, Shiro Takahara, Yoshitaka Isaka

Journal:

Kidney Research and Clinical Practice

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

83

Deficiency of Claudin-18 Causes Paracellular H+ Leakage, Up-regulation of Interleukin-1β, and Atrophic Gastritis in Mice

Daisuke Hayashi, Atsushi Tamura, Hiroo Tanaka, Yuji Yamazaki, Shin Watanabe, Koya Suzuki, Kazuo Suzuki, Kazuhiro Sentani, Wataru Yasui, Hiromi Rakugi, Yoshitaka Isaka, Sachiko Tsukita

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 7.18 MB

english, 2012

84

Non-myeloablative conditioning is sufficient to induce mixed chimerism and subsequent acceptance of donor specific cardiac and skin grafts

Liu, Chi, Zhu, Ping, Saito, Taro, Isaka, Yoshitaka, Nagahara, Yukitoshi, Zhuang, Jian, Li, Xiao-Kang

Journal:

International Immunopharmacology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

85

Renal transplantations from parents to siblings with autosomal recessive Alport syndrome caused by a rearrangement in an intronic antisenseAluelement in theCOL4A3gene led to different outcomes

Jun-ya Kaimori, Naotsugu Ichimaru, Yoshitaka Isaka, Fusako Hashimoto…

Journal:

CEN Case Reports

Year:

2013

Language:

english

File:

PDF, 412 KB

english, 2013

86

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Maejima, Ikuko, Takahashi, Atsushi, Omori, Hiroko, Kimura, Tomonori, Takabatake, Yoshitsugu, Saitoh, Tatsuya, Yamamoto, Akitsugu, Hamasaki, Maho, Noda, Takeshi, Isaka, Yoshitaka, Yoshimori, Tamotsu

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 5.41 MB

english, 2013

87

Electroporation-mediated gene therapy

Isaka, Yoshitaka, Imai, Enyu

Journal:

Expert Opinion on Drug Delivery

Year:

2007

Language:

english

File:

PDF, 435 KB

english, 2007

88

Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure

Matsui, Isao, Hamano, Takayuki, Mikami, Satoshi, Fujii, Naohiko, Takabatake, Yoshitsugu, Nagasawa, Yasuyuki, Kawada, Noritaka, Ito, Takahito, Rakugi, Hiromi, Imai, Enyu, Isaka, Yoshitaka

Journal:

Kidney International

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

89

Membranous nephropathy secondary to Graves’ disease with deposits of thyroid peroxidase in an adult

Sasaki, Koichi, Yasuda, Keiko, Nakanishi, Koichi, Rakugi, Hiromi, Isaka, Yoshitaka, Yamato, Masaya

Journal:

CEN Case Reports

Year:

2014

Language:

english

File:

PDF, 350 KB

english, 2014

90

An association between serum γ-glutamyltransferase and proteinuria in drinkers and non-drinkers: a Japanese nationwide cross-sectional survey

Ishigami, Toshihiro, Yamamoto, Ryohei, Nagasawa, Yasuyuki, Isaka, Yoshitaka, Rakugi, Hiromi, Iseki, Kunitoshi, Yamagata, Kunihiro, Tsuruya, Kazuhiko, Yoshida, Hideaki, Fujimoto, Shouichi, Asahi, Koich

Journal:

Clinical and Experimental Nephrology

Year:

2014

Language:

english

File:

PDF, 374 KB

english, 2014

91

DONOR-SPECIFIC TOLERANCE INDUCED BY TREATMENT WITH SUPERAGONISTIC CD28 ANTIBODY IN RAT RENAL ALLOGRAFTS

Azuma, Haruhito, Nohmi, Hayahito, Ubai, Takanobu, Inamoto, Teruo, Ibuki, Naokazu, Koyama, Kouhei, Isaka, Yoshitaka, Takahara, Shiro, Katsuoka, Yoji

Journal:

The Journal of Urology

Year:

2009

Language:

english

File:

PDF, 175 KB

english, 2009

92

Does Hypomagnesemia Predict Faster Progression of Nondiabetic Chronic Kidney Disease?

Sakaguchi, Yusuke, Tsubakihara, Yoshiharu, Rakugi, Hiromi, Isaka, Yoshitaka

Journal:

The American Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 76 KB

english, 2014

93

SYSTEMIC ADMINISTRATION OF SIRNA TARGETING P53 PROTECTS KIDNEYS FROM ISCHEMIA-REPERFUSION INJURY IN EXPERIMENTAL RAT KIDNEY TRANSPLANTATION MODEL

Imamura, Ryoichi, Isaka, Yoshitaka, Sandoval, Ruben M, Kakuta, Yoichi, Abe, Toyofumi, Okumi, Masayoshi, Ichimaru, Naotsugu, Takada, Shingo, Matsumiya, Kiyomi, Molitoris, Bruce A, Okuyama, Akihiko, Tak

Journal:

The Journal of Urology

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

94

Rhabdomyolysis caused by peripheral T-cell lymphoma in skeletal muscle

Sasaki, Koichi, Yamato, Masaya, Yasuda, Keiko, Rakugi, Hiromi, Isaka, Yoshitaka

Journal:

The American Journal of Emergency Medicine

Year:

2013

Language:

english

File:

PDF, 926 KB

english, 2013

95

Oligonucleotidic therapeutics

Isaka, Yoshitaka, Imai, Enyu, Takahara, Shiro, Rakugi, Hiromi

Journal:

Expert Opinion on Drug Discovery

Year:

2008

Language:

english

File:

PDF, 252 KB

english, 2008

96

The Authors Reply:

Sakaguchi, Yusuke, Fujii, Naohiko, Shoji, Tatsuya, Hayashi, Terumasa, Rakugi, Hiromi, Iseki, Kunitoshi, Tsubakihara, Yoshiharu, Isaka, Yoshitaka

Journal:

Kidney International

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

97

Gene therapy for kidney disease

Imai, Enyu, Isaka, Yoshitaka

Journal:

Expert Opinion on Investigational Drugs

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

98

Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Mellitus

Kothare, Prajakti A., Linnebjerg, Helle, Isaka, Yoshitaka, Uenaka, Kazunori, Yamamura, Ayuko, Yeo, Kwee Poo, de la Peña, Amparo, Teng, Choo Hua, Mace, Kenneth, Fineman, Mark, Shigeta, Hirofumi, Sakata

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

99

Fibroblast growth factor 23 and 25-hydroxyvitamin D levels are associated with estimated glomerular filtration rate decline

Hamano, Takayuki, Nakano, Chikako, Obi, Yoshitsugu, Fujii, Naohiko, Matsui, Isao, Tomida, Kodo, Mikami, Satoshi, Inoue, Kazunori, Shimomura, Akihiro, Kusunoki, Yasuo, Rakugi, Hiromi, Isaka, Yoshitaka,

Journal:

Kidney International Supplements

Year:

2013

Language:

english

File:

PDF, 338 KB

english, 2013

100

Implausible similarities in patient characteristics between two randomized controlled studies: a coincidence is unlikely

Obi, Yoshitsugu, Hama, Hitomi, Suzuki, Yoshiki, Isaka, Yoshitaka, Moriyama, Toshiki

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 93 KB

english, 2012