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51

The epigenome of colorectal cancer

Minoru Toyota, Hiromu Suzuki, Yasuhisa Shinomura

Journal:

Current Colorectal Cancer Reports

Year:

2009

Language:

english

File:

PDF, 362 KB

english, 2009

52

Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer

Reo Maruyama, Hiromu Suzuki, Eiichiro Yamamoto, Kohzoh Imai, Yasuhisa Shinomura

Journal:

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

53

Peroxisome Proliferator-activated Receptor γ Induces Growth Arrest and Differentiation Markers of Human Colon Cancer Cells

Shinji Kitamura, Yoshiji Miyazaki, Yasuhisa Shinomura, Shinya Kondo, Shuji Kanayama, Yuji Matsuzawa

Journal:

Year:

1999

Language:

english

File:

PDF, 415 KB

english, 1999

54

Structure, Expression and Chromosome Mapping of MLZE, a Novel Gene Which Is Preferentially Expressed in Metastatic Melanoma Cells

Kenji Watabe, Akihiko Ito, Hideo Asada, Yuichi Endo, Toshiko Kobayashi, Ken'i Nakamoto, Satoshi Itami, Sonshin Takao, Yasuhisa Shinomura, Takashi Aikou, Kunihiko Yoshikawa, Yuji Matsuzawa, Yukihiko Ki

Journal:

Year:

2001

Language:

english

File:

PDF, 4.66 MB

english, 2001

55

Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth

Masayo Hosokawa, Kotoe Kashiwaya, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Mutsuo Furihata, Yasuhisa Shinomura, Kohzoh Imai, Yusuke Nakamura, Hidewaki Nakagawa

Journal:

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

56

Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis

Kotoe Kashiwaya, Masayo Hosokawa, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Yasuhisa Shinomura, Yusuke Nakamura, Hidewaki Nakagawa

Journal:

Year:

2009

Language:

english

File:

PDF, 485 KB

english, 2009

57

Disturbed gastrointestinal motility and decreased interstitial cells of Cajal in diabetic db/db mice

Takahiro Yamamoto, Kenji Watabe, Masanori Nakahara, Hideharu Ogiyama, Tatsuya Kiyohara, Shusaku Tsutsui, Shinji Tamura, Yasuhisa Shinomura, Norio Hayashi

Journal:

Journal of Gastroenterology and Hepatology

Year:

2008

Language:

english

File:

PDF, 969 KB

english, 2008

58

INSULIN-LIKE GROWTH FACTOR-I RECEPTOR AS A CANDIDATE FOR A NOVEL MOLECULAR TARGET IN GASTROINTESTINAL CANCERS

Yasushi Adachi, Hiroyuki Yamamoto, Arisa Imsumran, Toshikuni Oka, Mariko Oki, Katsuhiko Nosho, Yongfen Min, Yasuhisa Shinomura, Choon-Taek Lee, David P. Carbone, Kohzoh Imai

Journal:

Digestive Endoscopy

Year:

2006

Language:

english

File:

PDF, 238 KB

english, 2006

59

Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cells

Zushi, Shinichiro, Kitamura, Shinji, Ueyama, Harumi, Matsuzawa, Yuji, Kondo, Shinya, Shinomura, Yasuhisa, Kanayama, Shuji, Higashimoto, Yoshifumi, Kiyohara, Tatsuya

Journal:

Year:

1998

Language:

english

File:

PDF, 416 KB

english, 1998

60

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers

Taniguchi, Hiroaki, Yamamoto, Hiroyuki, Hirata, Tamaki, Miyamoto, Nobuki, Oki, Mariko, Nosho, Katsuhiko, Adachi, Yasushi, Endo, Takao, Imai, Kohzoh, Shinomura, Yasuhisa

Journal:

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

61

Antisense therapy of MAdCAM-1 for trinitrobenzenesulfonic acid-induced murine colitis

Akira Goto, Yoshiaki Arimura, Yasuhisa Shinomura, Kohzoh Imai, Yuji Hinoda

Journal:

Inflammatory Bowel Diseases

Year:

2006

Language:

english

File:

PDF, 2.17 MB

english, 2006

62

IS HELICOBACTER PYLORI-INDUCED ENLARGED FOLD GASTRITIS A HIGH-RISK FACTOR FOR GASTRIC CARCINOMA?

Yoko Murayama, Yasuhisa Shinomura, Tamana Miyazaki, Shinji Tamura, Norio Hayashi

Journal:

Digestive Endoscopy

Year:

2006

Language:

english

File:

PDF, 422 KB

english, 2006

63

E-cadherin Gene Promoter Hypermethylation in H. pylori-Induced Enlarged Fold Gastritis

Tamana Miyazaki, Yoko Murayama, Yasuhisa Shinomura, Takahiro Yamamoto, Kenji Watabe, Shusaku Tsutsui, Tatsuya Kiyohara, Shinji Tamura, Norio Hayashi

Journal:

Year:

2007

Language:

english

File:

PDF, 699 KB

english, 2007

64

Expression of hepatocyte growth factor and c-met in ulcerative colitis

Shinji Kitamura, Shinya Kondo, Yasuhisa Shinomura, Kouji Isozaki, Shuji Kanayama, Yoshifumi Higashimoto, Takeshi Minami, Tatsuya Kiyohara, Yuichi Yasunaga, Hideki Ishikawa, Toru Ohtani, Shingo Ishigur

Journal:

Inflammation Research

Year:

2000

Language:

english

File:

PDF, 199 KB

english, 2000

65

Opossum (Didelphis virginiana) “little” and “big” gastrins

Yasuhisa Shinomura, John Eng, Satish C. Rattan, Rosalyn S. Yalow

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1990

Language:

english

File:

PDF, 253 KB

english, 1990

66

Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers

Hirokazu Ohashi, Yasushi Adachi, Hiroyuki Yamamoto, Hiroaki Taniguchi, Katsuhiko Nosho, Hiromu Suzuki, Yoshiaki Arimura, Kohzoh Imai, David P. Carbone, Yasuhisa Shinomura

Journal:

Year:

2012

Language:

english

File:

PDF, 758 KB

english, 2012

67

A case of Ménétrier's disease without Helicobacter pylori infection

Takao Endo, Yoshiaki Arimura, Yasushi Adachi, Hiroaki Mita, Kentaro Yamashita, Hiroyuki Yamamoto, Yasuhisa Shinomura, Yoshifumi Ishii

Journal:

Digestive Endoscopy

Year:

2012

Language:

english

File:

PDF, 2.55 MB

english, 2012

68

Heparin-Binding EGF-like Growth Factor Is an Autocrine Growth Factor for Rat Gastric Epithelial Cells

Yoshiji Miyazaki, Yasuhisa Shinomura, Shigeki Higashiyama, Shuji Kanayama, Yoshifumi Higashimoto, Shusaku Tsutsui, Shinichiro Zushi, Naoyuki Taniguchi, Yuji Matsuzawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 455 KB

english, 1996

69

Oxidative Stress Increases Gene Expression of Heparin-Binding EGF-like Growth Factor and Amphiregulin in Cultured Rat Gastric Epithelial Cells

Yoshiji Miyazaki, Yasuhisa Shinomura, Shusaku Tsutsui, Yuichi Yasunaga, Shinichiro Zushi, Shigeki Higashiyama, Naoyuki Taniguchi, Yuji Matsuzawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 131 KB

english, 1996

70

Induction of Heparin Binding Epidermal Growth Factor-like Growth Factor and Amphiregulin mRNAs by Gastrin in the Rat Stomach

Shusaku Tsutsui, Yasuhisa Shinomura, Shigeki Higashiyama, Yoshifumi Higashimoto, Yoshiji Miyazaki, Shuji Kanayama, Shintaro Hiraoka, Takeshi Minami, Shinji Kitamura, Yoko Murayama, Junichiro Miyagawa,

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 299 KB

english, 1997

71

PPARγ Inhibits the Expression of c-MET in Human Gastric Cancer Cells through the Suppression of Ets

Shinji Kitamura, Yoshiji Miyazaki, Shintaro Hiraoka, Miyuki Toyota, Yutaka Nagasawa, Shinya Kondo, Tatsuya Kiyohara, Yasuhisa Shinomura, Yuji Matsuzawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 72 KB

english, 1999

72

Purification and characterization of a phospholipase A2 from human ileal mucosa

Minami Takeshi, Tojo Hiromasa, Shinomura Yasuhisa, Matsuzawa Yuji, Okamoto Mitsuhiro

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1993

Language:

english

File:

PDF, 854 KB

english, 1993

73

Chinchilla “big” and “little” gastrins

Yasuhisa Shinomura, John Eng, Rosalyn S. Yalow

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 430 KB

english, 1987

74

Presence of glucagon-(1–21)-like immunoreactive substance in the dog small intestinal mucosa

Hidehiko Itoh, Mitsuyoshi Namba, Nobuaki Watanabe, Toshiko Ohara, Tatsuo Matsuyama, Ryoya Komatsu, Yasuhisa Shinomura, Norio Kono, Seiichiro Tarui

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 443 KB

english, 1989

75

Purification of N-terminal hexapeptide of big gastrin from human urine

Yoshifumi Higashimoto, Yasuhisa Shinomura, Kazuhiro Nagao, Yuichi Yasunaga, Toshiaki Tamura, Seiichiro Tarui

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 437 KB

english, 1990

76

Clinicopathologic similarities between Mikulicz disease and Küttner tumor

Ken-ichi Takano, Motohisa Yamamoto, Hiroki Takahashi, Yasuhisa Shinomura, Kohzoh Imai, Tetsuo Himi

Journal:

American Journal of Otolaryngology

Year:

2010

Language:

english

File:

PDF, 568 KB

english, 2010

77

Distinct roles for the SgIGSF adhesion molecule and c-kit receptor tyrosine kinase in the interaction between mast cells and the mesentery

Kenji Watabe, Akihiko Ito, Yu-ichiro Koma, Tomohiko Wakayama, Shoichi Iseki, Yasuhisa Shinomura, Yukihiko Kitamura

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 588 KB

english, 2004

78

Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability

Nobuki Miyamoto, Hiroyuki Yamamoto, Hiroaki Taniguchi, Chie Miyamoto, Mariko Oki, Yasushi Adachi, Kohzoh Imai, Yasuhisa Shinomura

Journal:

Year:

2007

Language:

english

File:

PDF, 2.95 MB

english, 2007

79

Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis

Katsuhiko Nosho, Hiroyuki Yamamoto, Masashi Mikami, Hiroaki Taniguchi, Taiga Takahashi, Yasushi Adachi, Akimichi Imamura, Kohzoh Imai, Yasuhisa Shinomura

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 496 KB

english, 2006

80

Correlation of laterally spreading type and JC virus with methylator phenotype status in colorectal adenoma

Katsuhiko Nosho, Hiroyuki Yamamoto, Taiga Takahashi, Masashi Mikami, Keiichi Hizaki, Tadateru Maehata, Hiroaki Taniguchi, Satoshi Yamaoka, Yasushi Adachi, Fumio Itoh, Kohzoh Imai, Yasuhisa Shinomura

Journal:

Human Pathology

Year:

2008

Language:

english

File:

PDF, 1.34 MB

english, 2008

81

The immunobiology and clinical characteristics of IgG4 related diseases

Hiroki Takahashi, Motohisa Yamamoto, Tetsuya Tabeya, Chisako Suzuki, Yasuyoshi Naishiro, Yasuhisa Shinomura, Kohzoh Imai

Journal:

Journal of Autoimmunity

Year:

2012

Language:

english

File:

PDF, 157 KB

english, 2012

82

Basic fibroblast growth factor promotes the trans-differentiation of mouse bone marrow cells into hepatic lineage cells via multiple liver-enriched transcription factors

Yukiko Saji, Shinji Tamura, Yuichi Yoshida, Shinichi Kiso, Ayuko Saeki Iizuka, Hitoshi Matsumoto, Takako Kawasaki, Yoshihiro Kamada, Yuji Matsuzawa, Yasuhisa Shinomura

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 226 KB

english, 2004

83

Increased Expression of a Nucleolar Nop5/Sik Family Member in Metastatic Melanoma Cells: Evidence for Its Role in Nucleolar Sizing and Function

Ken’i Nakamoto, Akihiko Ito, Kenji Watabe, Yu-ichiro Koma, Hideo Asada, Kunihiko Yoshikawa, Yasuhisa Shinomura, Yuji Matsuzawa, Hiroshi Nojima, Yukihiko Kitamura

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 1.44 MB

english, 2001

84

Purification and structural determination of urinary NH2-terminal big gastrin fragments

Yoshifumi Higashimoto, Seiichi Himeno, Yasuhisa Shinomura, Kazuhiro Nagao, Toshiaki Tamura, Seiichiro Tarui

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 345 KB

english, 1989

85

Peroxisome proliferator-activated receptor γ reduces the growth rate of pancreatic cancer cells through the reduction of cyclin D1

Miyuki Toyota, Yoshiji Miyazaki, Shinji Kitamura, Yutaka Nagasawa, Tatsuya Kiyohara, Yasuhisa Shinomura, Yuji Matsuzawa

Journal:

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

86

Dose-dependent and time-limited proliferation of cultured murine interstitial cells of Cajal in response to stem cell factor

Masanori Nakahara, Koji Isozaki, Jean-Marie Vanderwinden, Yasuhisa Shinomura, Yukihiko Kitamura, Seiichi Hirota, Yuji Matsuzawa

Journal:

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

87

Calphostin C induces expression of amphiregulin mRNA via reactive oxygen species in IEC-6 cells

Yoshiji Miyazaki, Yasuhisa Shinomura, Shusaku Tsutsui, Shinji Kitamura, Shintaro Hiraoka, Yuji Matsuzawa

Journal:

Year:

1998

Language:

english

File:

PDF, 436 KB

english, 1998

88

Model of translational cancer research in multiple myeloma

Hiroshi Yasui, Tadao Ishida, Reo Maruyama, Masanori Nojima, Hiroshi Ikeda, Hiromu Suzuki, Toshiaki Hayashi, Yasuhisa Shinomura, Kohzoh Imai

Journal:

Year:

2012

Language:

english

File:

PDF, 214 KB

english, 2012

89

Extensive portal and mesenteric vein thrombosis in a young man with Klinefelter's syndrome

Yasutaka Matsunaga, Akira Goto, Hideki Wakasugi, Ayako Itoh, Kazuhiko Yonezawa, Miki Itoh, Kenichi Fujii, Kazuya Suzuki, Takashi Abe, Keiko Ushijima, Yasuhisa Shinomura

Journal:

Hepatology Research

Year:

2012

Language:

english

File:

PDF, 795 KB

english, 2012

90

DNA Hypermethylation Contributes to Incomplete Synthesis of Carbohydrate Determinants in Gastrointestinal Cancer

Yuki I. Kawamura, Minoru Toyota, Rei Kawashima, Teruki Hagiwara, Hiromu Suzuki, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino, Reiji Kannagi, Taeko Dohi

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 1.71 MB

english, 2008

91

Dog secretin: Sequence and biologic activity

Yasuhisa Shinomura, John Eng, Rosalyn S. Yalow

Journal:

Year:

1987

Language:

english

File:

PDF, 290 KB

english, 1987

92

NH2-terminal big gastrin immunoreactivity in human urine

Yoshifumi Higashimoto, Seiichi Himeno, Yasuhisa Shinomura, Shuji Kanayama, Kazuhiro Nagao, Seiichiro Tarui

Journal:

Year:

1990

Language:

english

File:

PDF, 527 KB

english, 1990

93

Marked increase in gastric histidine decarboxylase activity in patients with hypergastrinemia

Yoshiji Miyazaki, Ikuo Imamura, Yasuhisa Shinomura, Hiroshi Wada, Seiichiro Tarui

Journal:

Year:

1991

Language:

english

File:

PDF, 391 KB

english, 1991

94

Immunoreactive glucagons purified from dog pancreas, stomach and ileum

Yasuhisa Shinomura, John Eng, Rosalyn S. Yalow

Journal:

Regulatory Peptides

Year:

1988

Language:

english

File:

PDF, 566 KB

english, 1988

95

Effect of cholecystokinin receptor antagonists, MK-329 and L-365,260, on cholecystokinin-induced acid secretion and histidine decarboxylase activity in the rat

Shigeharu Kawabata, Shuji Kanayama, Yasuhisa Shinomura, Yoshiji Miyazaki, Ikuo Imamura, Kaname Moriwaki, Hiroshi Wada, Seiichiro Tarui

Journal:

Regulatory Peptides

Year:

1991

Language:

english

File:

PDF, 508 KB

english, 1991

96

A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors

Masanori Nakahara, Koji Isozaki, Seiichi Hirota, Jun-Ichiro Miyagawa, Naoko Hase-Sawada, Masahiko Taniguchi, Toshirou Nishida, Suji Kanayama, Yukihiko Kitamura, Yasuhisa Shinomura, Yuji Matsuzawa

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 519 KB

english, 1998

97

Gastrin induces heparin-binding epidermal growth factor–like growth factor in rat gastric epithelial cells transfected with gastrin receptor

Yoshiji Miyazaki, Yasuhisa Shinomura, Shusaku Tsutsui, Shinichiro Zushi, Yoshifumi Higashimoto, Shuji Kanayama, Shigeki Higashiyama, Naoyuki Taniguchi, Yuji Matsuzawa

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 389 KB

english, 1999

98

Flat-type colorectal advanced adenomas (laterally spreading tumors) have different genetic and epigenetic alterations from protruded-type advanced adenomas

Takahashi, Taiga, Nosho, Katsuhiko, Yamamoto, Hiroyuki, Mikami, Masashi, Taniguchi, Hiroaki, Miyamoto, Nobuki, Adachi, Yasushi, Itoh, Fumio, Imai, Kohzoh, Shinomura, Yasuhisa

Journal:

Modern Pathology

Year:

2007

Language:

english

File:

PDF, 402 KB

english, 2007

99

Area between the hepatic and heart curves of99mTc-galactosyl-human serum albumin scintigraphy represents liver function and disease progression for preoperative evaluation in hepatocellular carcinoma patients

Kohei Harada, Toru Mizuguchi, Yoshimi Katagiri, Masaki Kawamoto, Yukio Nakamura, Makoto Meguro, Shigenori Ota, Shigeru Sasaki, Koji Miyanishi, Tomoko Sonoda, Mitsuru Mori, Yasuhisa Shinomura, Junji Ka

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2012

Language:

english

File:

PDF, 470 KB

english, 2012

100

Desmoplastic malignant mesothelioma originating from the peritoneum

Hiroyuki Takamaru, Yoshiaki Arimura, Yasuhisa Shinomura

Journal:

Medical Oncology

Year:

2012

Language:

english

File:

PDF, 328 KB

english, 2012