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1

History of gene therapy

Wirth, Thomas, Parker, Nigel, Ylä-Herttuala, Seppo

Journal:

Year:

2013

Language:

english

File:

PDF, 865 KB

english, 2013

2

Gene Editing of Human Embryos with CRISPR/Cas9: Great Promise Coupled with Important Caveats

Schenkwein, Diana, Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 120 KB

english, 2018

3

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

Moreau, Pierre R., Örd, Tiit, Downes, Nicholas L., Niskanen, Henri, Bouvy-Liivrand, Maria, Aavik, Einari, Ylä-Herttuala, Seppo, Kaikkonen, Minna U.

Journal:

Frontiers in Cardiovascular Medicine

Year:

2018

Language:

english

File:

PDF, 2.82 MB

english, 2018

4

Adverse effects of gene therapy: Hero or villain?

Ylä-Herttuala, S

Journal:

Year:

2003

Language:

english

File:

PDF, 59 KB

english, 2003

5

Recent Advancements in Cardiovascular Gene Therapy and Vascular Biology

Laakkonen, Johanna, Ylä-Herttuala, Seppo

Journal:

Human Gene Therapy

Year:

2015

Language:

english

File:

PDF, 286 KB

english, 2015

6

Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

Frederickson, Robert M., Moghimi, SM, Wagner, E, Yla-Herttuala, Seppo

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 309 KB

english, 2016

7

Autoantibodies Against Oxidized Low Density Lipoprotein in Patients With Angiographically Verified Coronary Artery Disease

Lehtimaki, T., Lehtinen, S., Solakivi, T., Nikkila, M., Jaakkola, O., Jokela, H., Yla-Herttuala, S., Luoma, J. S., Koivula, T., Nikkari, T.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1999

Language:

english

File:

PDF, 545 KB

english, 1999

8

ADVANCES AND CHALLENGES IN CARDIOVASCULAR GENE THERAPY

Ylä-Herttuala, Seppo, Lähteenvuo, Johanna

Journal:

Human Gene Therapy

Year:

2017

Language:

english

File:

PDF, 981 KB

english, 2017

9

ADA-SCID Gene Therapy Endorsed By European Medicines Agency For Marketing Authorization

Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 190 KB

english, 2016

10

Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice

Sunkari, Vivekananda Gupta, Lind, Folke, Botusan, Ileana Ruxandra, Kashif, Abad, Liu, Zhao-Jun, Ylä-Herttuala, Seppo, Brismar, Kerstin, Velazquez, Omaida, Catrina, Sergiu-Bogdan

Journal:

Wound Repair and Regeneration

Year:

2015

Language:

english

File:

PDF, 765 KB

english, 2015

11

Gene Therapy: The First Approved Gene-Based Medicines, Molecular Mechanisms and Clinical Indications

Raty, J., Pikkarainen, J., Wirth, T., Yla-Herttuala, S.

Journal:

Current Molecular Pharmacology

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

12

Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL

Anna-Mari Heikkinen, Leo Niskanen, Seppo Ylä-Herttuala, Jukka Luoma, Marjo T. Tuppurainen, Marja Komulainen, Seppo Saarikoski

Journal:

Year:

1998

Language:

english

File:

PDF, 84 KB

english, 1998

13

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor

Gurzeler, Erika, Aavik, Einari, Laine, Anssi, Valkama, Teemu, Niskanen, Henri, Huusko, Jenni, Kaikkonen, Minna U., Ylä-Herttuala, Seppo

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2018

Language:

english

File:

PDF, 18.54 MB

english, 2018

14

CMR 2005: 12.06: Ultra-small iron oxide nanoparticle (USPIO)-labeled baculoviruses as novel MRI agents for imaging viral vector biodistribution in vivo

J. Hakumäki, J. Räty, T. Wirth, T. Huhtala, T. Ihalainen, M. Vihinen-Ranta, A. Närvänen, S. Ylä-Herttuala

Journal:

Contrast Media & Molecular Imaging

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

15

Epigenetics and atherosclerosis

Mikko P. Turunen, Einari Aavik, Seppo Ylä-Herttuala

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 481 KB

english, 2009

16

Generation of lentivirus vectors using recombinant baculoviruses

Lesch, H P, Turpeinen, S, Niskanen, E A, Mähönen, A J, Airenne, K J, Ylä-Herttuala, S

Journal:

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

17

Avidin-biotin technology in targeted therapy

Lesch, Hanna P, Kaikkonen, Minna U, Pikkarainen, Jere T, Ylä-Herttuala, Seppo

Journal:

Expert Opinion on Drug Delivery

Year:

2010

Language:

english

File:

PDF, 625 KB

english, 2010

18

Growth Factor Therapy and Autologous Lymph Node Transfer in Lymphedema

Lahteenvuo, M., Honkonen, K., Tervala, T., Tammela, T., Suominen, E., Lahteenvuo, J., Kholova, I., Alitalo, K., Yla-Herttuala, S., Saaristo, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 5.40 MB

english, 2011

19

Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease

Onni Nlemelä, Seppo Parkkila, Seppo Ylä-herttuala, Jesus Villanueva, Boris Ruebner, Charles H. Halsted

Journal:

Year:

1995

Language:

english

File:

PDF, 823 KB

english, 1995

20

Molecular genetics of atherosclerosis

Himadri Roy, Shalini Bhardwaj, Seppo Yla-Herttuala

Journal:

Year:

2009

Language:

english

File:

PDF, 920 KB

english, 2009

21

Clinical applications of vascular gene therapy

Juha Rutanen, Tuomas T. Rissanen, Antti Kivelä, Ismo Vajanto, Seppo Ylä-Herttuala

Journal:

Current Cardiology Reports

Year:

2001

Language:

english

File:

PDF, 355 KB

english, 2001

22

Antegrade flow and peripheral resistance determine the level of endogenous arteriogenesis in patients with superficial femoral artery occlusion

I. Vajanto, P. Korpisalo, J. Karjalainen, T. Hakala, K. Mäkinen, S. Ylä-Herttuala

Journal:

European Journal of Clinical Investigation

Year:

2009

Language:

english

File:

PDF, 285 KB

english, 2009

23

Post-intervention vessel remodeling

Rutanen, J, Puhakka, H, Ylä-Herttuala, S

Journal:

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

24

Review focus on epigenetics and the histone code in vascular biology

Yla-Herttuala, S., Glass, C. K.

Journal:

Cardiovascular Research

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

25

Autoantibodies against oxidized LDL are associated with severe chest pain attacks in patients with coronary heart disease

Jukka S. Luoma, Anu Kareinen, Outi Närvänen, Laura Viitanen, Markku Laakso, Seppo Ylä-Herttuala

Journal:

Free Radical Biology and Medicine

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

26

Targeting and Purification of Metabolically Biotinylated Baculovirus

Kaikkonen, Minna U., Viholainen, Jenni I., Närvänen, Ale, Ylä-Herttuala, Seppo, Airenne, Kari J.

Journal:

Human Gene Therapy

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

27

Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis

Tammela, T., Saaristo, A., Holopainen, T., Yla-Herttuala, S., Andersson, L. C., Virolainen, S., Immonen, I., Alitalo, K.

Journal:

Science Translational Medicine

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

28

Effect of repeated endotoxin treatment and hypercholesterolemia on preatherosclerotic lesions in weaned pigs Part 11. Lipid and glycosaminoglycan analysis of intima and inner media

Seppo Ylä-Herttuala, Erkki Pesonen, Eero Kaprio, Juhani Rapola, Timo Soveri, Jorma Viikari, Erkki Savilahti, Hans Oksanen, Tapio Nikkari

Journal:

Atherosclerosis

Year:

1988

Language:

english

File:

PDF, 822 KB

english, 1988

29

Changes in gene expression in atherosclerotic plaques analyzed using DNA array

Mikko O Hiltunen, Tiina T Tuomisto, Mari Niemi, Jan H Bräsen, Tuomas T Rissanen, Petri Törönen, Ismo Vajanto, Seppo Ylä-Herttuala

Journal:

Atherosclerosis

Year:

2002

Language:

english

File:

PDF, 655 KB

english, 2002

30

5 Lipoprotein receptor gene expression in atherosclerotic lesions

Seppo Ylä-Herttuala

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 116 KB

english, 1997

31

Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5

Raine Toivonen, Juha Koskenvuo, Mari Merentie, Mirva Söderström, Seppo Ylä-Herttuala, Mikko Savontaus

Journal:

Virology Journal

Year:

2012

Language:

english

File:

PDF, 604 KB

english, 2012

32

Vascular Oligonucleotide Transfer Facilitated by a Polymer-Coated Stent

Radke, Peter W., Griesenbach, Uta, Kivela, Antti, Vick, Terry, Judd, Diane, Munkonge, Felix, Willis, Sean, Geddes, Duncan M., Yla-Herttuala, Seppo, Alton, Eric W.F.W.

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

33

DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

Hiltunen, Mikko O, Turunen, Mikko P, Häkkinen, Tomi P, Rutanen, Juha, Hedman, Marja, Mäkinen, Kimmo, Turunen, Anna-Mari, Aalto-Setälä, Katriina, Ylä-Herttuala, Seppo

Journal:

Vascular Medicine

Year:

2002

Language:

english

File:

PDF, 975 KB

english, 2002

34

Production of HIV-1 Integrase Fusion Protein-Carrying Lentiviral Vectors for Gene Therapy and Protein Transduction

Schenkwein, Diana, Turkki, Vesa, Kärkkäinen, Hanna-Riikka, Airenne, Kari, Ylä-Herttuala, Seppo

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 10.89 MB

english, 2010

35

VEGF Gene Transfer Reduces Intimal Thickening via Increased Production of Nitric Oxide in Carotid Arteries

Laitinen, Marja, Zachary, Ian, Breier, Georg, Pakkanen, Timo, Häkkinen, Tomi, Luoma, Jukka, Abedi, Husna, Risau, Werner, Soma, Maurizio, Laakso, Markku, Martin, John F., Ylä-Herttuala, Seppo

Journal:

Human Gene Therapy

Year:

1997

Language:

english

File:

PDF, 9.75 MB

english, 1997

36

Extracellular Superoxide Dismutase with Vaccinia Virus Anti-inflammatory Protein 35K or Tissue Inhibitor of Metalloproteinase-1: Combination Gene Therapy in the Treatment of Vein Graft Stenosis in Rabbits

Turunen, Päivi, Puhakka, Hanna L., Heikura, Tommi, Romppanen, Elina, Inkala, Matias, Leppänen, Olli, Ylä-Herttuala, Seppo

Journal:

Human Gene Therapy

Year:

2006

Language:

english

File:

PDF, 455 KB

english, 2006

37

Lymphatic Vessel Insufficiency in Hypercholesterolemic Mice Alters Lipoprotein Levels and Promotes Atherogenesis

Vuorio, T., Nurmi, H., Moulton, K., Kurkipuro, J., Robciuc, M. R., Ohman, M., Heinonen, S. E., Samaranayake, H., Heikura, T., Alitalo, K., Yla-Herttuala, S.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

38

Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation

Nguyen, Su Duy, Javanainen, Matti, Rissanen, Sami, Zhao, Hongxia, Huusko, Jenni, Kivelä, Annukka M., Ylä-Herttuala, Seppo, Navab, Mohamad, Fogelman, Alan M., Vattulainen, Ilpo, Kovanen, Petri T., Öörn

Journal:

The Journal of Lipid Research

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

39

Feasibility of experimental BT4C glioma models for somatostatin receptor 2-targeted therapies

Kiviniemi, Aida, Gardberg, Maria, Autio, Anu, Li, Xiang-Guo, Heuser, Vanina D., Liljenbäck, Heidi, Käkelä, Meeri, Sipilä, Henri, Kurkipuro, Jere, Ylä-Herttuala, Seppo, Knuuti, Juhani, Minn, Heikki, Ro

Journal:

Acta Oncologica

Year:

2014

Language:

english

File:

PDF, 2.28 MB

english, 2014

40

Ultrasound imaging with bolus delivered contrast agent for the detection of angiogenesis and blood flow irregularities

Korpisalo, P., Hytonen, J. P., Laitinen, J. T. T., Narvainen, J., Rissanen, T. T., Grohn, O. H., Yla-Herttuala, S.

Journal:

AJP Heart and Circulatory Physiology

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

41

From the Impact Factor to DORA and the Scientific Content of Articles

Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 92 KB

english, 2015

42

The level of autoantibodies against oxidized LDL is not associated with the presence of coronary heart disease or diabetic kidney disease in patients with non-insulin-dependent diabetes mellitus

Leinonen, Janne S., Rantalaiho, Vappu, Laippala, Pekka, Wirta, Ole, Pasternack, Amos, Alho, Hannu, Jaakkola, Olli, Ylä-Herttuala, Seppo, Koivula, Timo, Lehtimäki, Terho

Journal:

Free Radical Research

Year:

1998

Language:

english

File:

PDF, 547 KB

english, 1998

43

Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer 18F-fluoromethylcholine

Hellberg, Sanna, Silvola, Johanna M. U., Kiugel, Max, Liljenbäck, Heidi, Metsälä, Olli, Viljanen, Tapio, Metso, Jari, Jauhiainen, Matti, Saukko, Pekka, Nuutila, Pirjo, Ylä-Herttuala, Seppo, Knuuti, Ju

Journal:

Cardiovascular Diabetology

Year:

2016

Language:

english

File:

PDF, 1.99 MB

english, 2016

44

DNA methylation processes in atheosclerotic plaque

Einari, Aavik, Mohan, Babu, Ylä-Herttuala, Seppo

Journal:

Atherosclerosis

Year:

2018

Language:

english

File:

PDF, 1.19 MB

english, 2018

45

MP54-03 LENTIVIRAL INTERFERON: A NOVEL METHOD FOR GENE THERAPY IN BLADDER CANCER

Duplisea, Jonathan, Mokkapati, Sharada, Metcalfe, Michael, Dunner, Ken, Czerniak, Bogdan, Nieminen, Tiina, Heikura, Tommi, Yla-Herttuala, Seppo, Parker, Nigel, McConkey, David, Dinney, Colin

Journal:

The Journal of Urology

Year:

2018

Language:

english

File:

PDF, 439 KB

english, 2018

46

Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye

Kati Kinnunen, Giedrius Kalesnykas, Anssi J. Mähönen, Svetlana Laidinen, Liisa Holma, Tommi Heikura, Kari Airenne, Hannu Uusitalo, Seppo Ylä-Herttuala

Journal:

The Journal of Gene Medicine

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

47

Baseline Diene Conjugation in LDL Lipids as a Direct Measure of In Vivo LDL Oxidation

Markku Ahotupa, Jukka Marniemi, Terho Lehtimäki, Kati Talvinen, Olli T. Raitakari, Tommi Vasankari, Jorma Viikari, Jukka Luoma, Seppo Ylä-Herttuala

Journal:

Clinical Biochemistry

Year:

1998

Language:

english

File:

PDF, 167 KB

english, 1998

48

Low Efficacy of Gene Therapy for Rat BT4C Malignant Glioma Using Intra-Tumoural Transduction with Thymidine Kinase Retrovirus Packaging Cell Injections and Ganciclovir Treatment

A.-M. Sandmair, S. Loimas, H. Poptani, P. Vainio, R. Vanninen, M. Turunen, K. Tyynelä, M. Vapalahti, S. Ylä-Herttuala

Journal:

Acta Neurochirurgica

Year:

1999

Language:

english

File:

PDF, 382 KB

english, 1999

49

Progress and prospects: hurdles to cardiovascular gene therapy clinical trials

Hedman, M, Hartikainen, J, Ylä-Herttuala, S

Journal:

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

50

Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes

Laurema, A, Heikkilä, A, Keski-Nisula, L, Heikura, T, Lehtolainen, P, Manninen, H, Tuomisto, T T, Heinonen, S, Ylä-Herttuala, S

Journal:

Year:

2003

Language:

english

File:

PDF, 232 KB

english, 2003

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