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1

From cells to genes: how to make antibodies useful in human diagnosis and therapy

Manuela Zaccolo, Fabio Malavasi

Journal:

International Journal of Clinical & Laboratory Research

Year:

1993

Language:

english

File:

PDF, 930 KB

english, 1993

2

cAMP signaling in subcellular compartments

Lefkimmiatis, Konstantinos, Zaccolo, Manuela

Journal:

Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 809 KB

english, 2014

3

PGE1Stimulation of HEK293 Cells Generates Multiple Contiguous Domains with Different [cAMP]: Role of Compartmentalized Phosphodiesterases

Anna Terrin, Giulietta Di Benedetto, Vanessa Pertegato, York-Fong Cheung, George Baillie, Martin J. Lynch, Nicola Elvassore, Anke Prinz, Friedrich W. Herberg, Miles D. Houslay and Manuela Zaccolo

Journal:

The Journal of Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.91 MB

english, 2006

4

Charged-Particle Multiplicity Distributions over a Wide Pseudorapidity Range in Proton–Proton Collisions with ALICE

Zaccolo, Valentina

Journal:

Nuclear Physics A

Year:

2016

Language:

english

File:

PDF, 607 KB

english, 2016

5

Increase in Ca 2+ current by sustained cAMP levels enhances proliferation rate in GH3 cells

Rodrigues, Andréia Laura, Brescia, Marcella, Koschinski, Andreas, Moreira, Thaís Helena, Cameron, Ryan T., Baillie, George, Beirão, Paulo S.L., Zaccolo, Manuela, Cruz, Jader S.

Journal:

Year:

2018

Language:

english

File:

PDF, 895 KB

english, 2018

6

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β 2 AR-cAMP Responsiveness in Murine Hearts

Wright, Peter T., Bhogal, Navneet K., Diakonov, Ivan, Pannell, Laura M.K., Perera, Ruwan K., Bork, Nadja I., Schobesberger, Sophie, Lucarelli, Carla, Faggian, Giuseppe, Alvarez-Laviada, Anita, Zaccolo

Journal:

Year:

2018

Language:

english

File:

PDF, 3.39 MB

english, 2018

7

Subcellular Organization of the cAMP Signaling Pathway

Zaccolo, Manuela, Zerio, Anna, Lobo, Miguel J., Garland, Christopher

Journal:

Pharmacological Reviews

Year:

2021

File:

PDF, 1.08 MB

2021

8

Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells

Manuela Zaccolo, Andrew P. Griffiths, Terence D. Prospero, Greg Winter, Ermanno Gherardi

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 998 KB

english, 1997

9

Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

Daniela Moll, Anke Prinz, Cornelia M Brendel, Marco Berrera, Katrin Guske, Manuela Zaccolo, Hans-Gottfried Genieser, Friedrich W Herberg

Journal:

BMC Biochemistry

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

10

Missense mutations in Desmocollin-2 N-terminus, associated with arrhythmogenic right ventricular cardiomyopathy, affect intracellular localization of desmocollin-2 in vitro

Giorgia Beffagna, Marzia De Bortoli, Andrea Nava, Michela Salamon, Alessandra Lorenzon, Manuela Zaccolo, Luisa Mancuso, Luca Sigalotti, Barbara Bauce, Gianluca Occhi, Cristina Basso, Gerolamo Lanfranc

Journal:

BMC Medical Genetics

Year:

2007

Language:

english

File:

PDF, 2.62 MB

english, 2007

11

Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart

Clint L. Miller, Yujun Cai, Masayoshi Oikawa, Tamlyn Thomas, Wolfgang R. Dostmann, Manuela Zaccolo, Keigi Fujiwara, Chen Yan

Journal:

Basic Research in Cardiology

Year:

2011

Language:

english

File:

PDF, 1014 KB

english, 2011

12

Compartmentalized cAMP/PKA signalling regulates cardiac excitation–contraction coupling

Valentina Lissandron, Manuela Zaccolo

Journal:

Journal of Muscle Research and Cell Motility

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

13

Association between drug prescribing and quality of life in primary care

Samanta E. Fröhlich, Anamaria V. Zaccolo, Sabrina L. C. da Silva, Sotero S. Mengue

Journal:

International Journal of Clinical Pharmacy

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

14

Space and time-resolved gene expression experiments on cultured mammalian cells by a single-cell electroporation microarray

S. Vassanelli, L. Bandiera, M. Borgo, G. Cellere, L. Santoni, C. Bersani, M. Salamon, M. Zaccolo, L. Lorenzelli, S. Girardi, M. Maschietto, M. Dal Maschio, A. Paccagnella

Journal:

New Biotechnology

Year:

2008

Language:

english

File:

PDF, 1.66 MB

english, 2008

15

Characterization by Monoclonal Antibody of a Highly Conserved Antigenic Determinant Expressed on Human Platelet Membranes and Intermediate Filament Type III

M. ALESSIO, G. BELLONE, A. FUNARO, L. B. DE MONTE, S. ROGGERO, L. PERUZZI, M. ZACCOLO, M. MOMO, A. P. M. CAPPA, F. MALAVASI

Journal:

Scandinavian Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 2.71 MB

english, 1990

16

cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies

Manuela Zaccolo

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 294 KB

english, 2009

17

10.1038/71345

Pozzan, Tullio, Zaccolo, Manuela, De Giorgi, Francesca, Cho, Charles Y., Feng, Luxin, Knapp, Tom, Negulescu, Paul A., Taylor, Susan S., Tsien, Roger Y.

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 414 KB

english, 2000

18

Unitary permeability of gap junction channels to second messengers measured by FRET microscopy

Hernandez, Victor H, Bortolozzi, Mario, Pertegato, Vanessa, Beltramello, Martina, Giarin, Michele, Zaccolo, Manuela, Pantano, Sergio, Mammano, Fabio

Journal:

Year:

2007

Language:

english

File:

PDF, 362 KB

english, 2007

19

Cell entry and cAMP imaging of anthrax edema toxin

Dal Molin, Federica, Tonello, Fiorella, Ladant, Daniel, Zornetta, Irene, Zamparo, Ilaria, Di Benedetto, Giulietta, Zaccolo, Manuela, Montecucco, Cesare

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 297 KB

english, 2006

20

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

Ponsioen, Bas, Zhao, Jun, Riedl, Jurgen, Zwartkruis, Fried, van der Krogt, Gerard, Zaccolo, Manuela, Moolenaar, Wouter H, Bos, Johannes L, Jalink, Kees

Journal:

Year:

2004

Language:

english

File:

PDF, 182 KB

english, 2004

21

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum

Lygren, Birgitte, Carlson, Cathrine Rein, Santamaria, Katja, Lissandron, Valentina, McSorley, Theresa, Litzenberg, Jessica, Lorenz, Dorothea, Wiesner, Burkhard, Rosenthal, Walter, Zaccolo, Manuela

Journal:

Year:

2007

Language:

english

File:

PDF, 339 KB

english, 2007

22

Mutations in the Insulin-Like Factor 3 Receptor Are Associated With Osteoporosis

Alberto Ferlin, Anastasia Pepe, Lisa Gianesello, Andrea Garolla, Shu Feng, Sandro Giannini, Manuela Zaccolo, Arianna Facciolli, Roy Morello, Alexander I Agoulnik, Carlo Foresta

Journal:

Journal of Bone and Mineral Research

Year:

2008

Language:

english

File:

PDF, 2.75 MB

english, 2008

23

CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity

Monterisi, S., Favia, M., Guerra, L., Cardone, R. A., Marzulli, D., Reshkin, S. J., Casavola, V., Zaccolo, M.

Journal:

Journal of Cell Science

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

24

Recombinant proteins L and LG

R. Vola, A. Lombardi, L. Tarditi, M. Zaccolo, D. Neri, L. Björck, M. Mariani

Journal:

Cell Biochemistry and Biophysics

Year:

1994

Language:

english

File:

PDF, 936 KB

english, 1994

25

Transgenic fruit-flies expressing a FRET-based sensor for in vivo imaging of cAMP dynamics

Valentina Lissandron, Maria Giovanna Rossetto, Karen Erbguth, André Fiala, Andrea Daga, Manuela Zaccolo

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 5.17 MB

english, 2007

26

PKA microdomain organisation and cAMP handling in healthy and dystrophic muscle in vivo

Ira Verena Röder, Valentina Lissandron, Jessica Martin, Yvonne Petersen, Giulietta Di Benedetto, Manuela Zaccolo, Rüdiger Rudolf

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 1.24 MB

english, 2009

27

Phosphodiesterases and compartmentalized cAMP signalling in the heart

Manuela Zaccolo

Journal:

European Journal of Cell Biology

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

28

Compartmentalisation of cAMP and Ca2+ signals

Manuela Zaccolo, Paulo Magalhães, Tullio Pozzan

Journal:

Current Opinion in Cell Biology

Year:

2002

Language:

english

File:

PDF, 697 KB

english, 2002

29

Regulation of the inflammatory response of vascular endothelial cells by EPAC1

Euan Parnell, Brian O Smith, Timothy M Palmer, Anna Terrin, Manuela Zaccolo, Stephen J Yarwood

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.67 MB

english, 2012

30

Photon Moment Analysis in Cells in the Presence of Photo-Bleaching

Caccia, Michele, Camozzi, Elisa, Collini, Maddalena, Zaccolo, Manuela, Chirico, Giuseppe

Journal:

Applied Spectroscopy

Year:

2005

Language:

english

File:

PDF, 130 KB

english, 2005

31

An Approach to Random Mutagenesis of DNA Using Mixtures of Triphosphate Derivatives of Nucleoside Analogues

Manuela Zaccolo, David M. Williams, Daniel M. Brown, Ermanno Gherardi

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 1.48 MB

english, 1996

32

The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 β-lactamase

Manuela Zaccolo, Ermanno Gherardi

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 272 KB

english, 1999

33

cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin

Federica Dal Molin, Irene Zornetta, Andrea Puhar, Fiorella Tonello, Manuela Zaccolo, Cesare Montecucco

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 666 KB

english, 2008

34

Small-molecule FRET probes for protein kinase activity monitoring in living cells

Angela Vaasa, Marje Lust, Anna Terrin, Asko Uri, Manuela Zaccolo

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 560 KB

english, 2010

35

Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia

Chunying Li, Partha C. Krishnamurthy, Himabindu Penmatsa, Kevin L. Marrs, Xue Qing Wang, Manuela Zaccolo, Kees Jalink, Min Li, Deborah J. Nelson, John D. Schuetz, Anjaparavanda P. Naren

Journal:

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

36

Spatial control of cAMP signalling in health and disease

Manuela Zaccolo

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 498 KB

english, 2011

37

Molecular basis of the allosteric mechanism of cAMP in the regulatory PKA subunit

Sergio Pantano, Manuela Zaccolo, Paolo Carloni

Journal:

Year:

2005

Language:

english

File:

PDF, 1.39 MB

english, 2005

38

Improvement of a FRET-based Indicator for cAMP by Linker Design and Stabilization of Donor–Acceptor Interaction

Valentina Lissandron, Anna Terrin, Maddalena Collini, Laura D'alfonso, Giuseppe Chirico, Sergio Pantano, Manuela Zaccolo

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 495 KB

english, 2005

39

Developmentally acquired PKA localisation in mouse oocytes and embryos

Rachel J. Webb, Lorna Tinworth, Geraint M.H. Thomas, Manuela Zaccolo, John Carroll

Journal:

Developmental Biology

Year:

2008

Language:

english

File:

PDF, 3.32 MB

english, 2008

40

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

Y.Y. Sin, H.V. Edwards, X. Li, J.P. Day, F. Christian, A.J. Dunlop, D.R. Adams, M. Zaccolo, M.D. Houslay, G.S. Baillie

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 1.59 MB

english, 2011

41

Human MYO18B, a Novel Unconventional Myosin Heavy Chain Expressed in Striated Muscles Moves into the Myonuclei upon Differentiation

Michela Salamon, Caterina Millino, Anna Raffaello, Marco Mongillo, Claudia Sandri, Camilla Bean, Enrico Negrisolo, Alberto Pallavicini, Giorgio Valle, Manuela Zaccolo, Stefano Schiaffino, Gerolamo Lan

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.73 MB

english, 2003

42

cAMP and Ca2+ interplay: a matter of oscillation patterns

Manuela Zaccolo, Tullio Pozzan

Journal:

Trends in Neurosciences

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

43

Microdomains of cAMP in heart cells

Journal:

Biomedicine & Pharmacotherapy

Year:

2002

Language:

english

File:

PDF, 34 KB

english, 2002

44

Chronic eosinophilic leukemia in a cat: cytochemical and immunophenotypical features

Maria Elena Gelain, Elisa Antoniazzi, Walter Bertazzolo, Maurizia Zaccolo, Stefano Comazzi

Journal:

Veterinary Clinical Pathology

Year:

2006

Language:

english

File:

PDF, 291 KB

english, 2006

45

Use of Chimeric Fluorescent Proteins and Fluorescence Resonance Energy Transfer to Monitor Cellular Responses

Journal:

Circulation Research

Year:

2004

Language:

english

File:

PDF, 495 KB

english, 2004

46

Localisation of PKR and HCV-NS5A in living cells using fusion proteins with different mutants of GFP

Stefano Realdon, Martina Gerotto, Francesca Dal Pero, Marco Mongillo, Manuela Zaccolo, Alfredo Alberti

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 139 KB

english, 2002

47

Ezrin and cAMP/PKA have different compartmentalization in CFBE410- and 16HBE14o- cells

S. Monterisi, M. Favia, L. Guerra, T. Fanelli, S.J. Reshkin, M. Zaccolo, M. Conese, V. Casavola

Journal:

Journal of Cystic Fibrosis

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

48

Microplate selection technique (MPST): A new method for selecting mouse transfectants expressing human gene products

L. Peruzzi, G. Melioli, L.B. De Monte, M. Alessio, M. Zaccolo, S. Roggero, G. Bellone, A. Funaro, F. Malavasi

Journal:

Journal of Immunological Methods

Year:

1989

Language:

english

File:

PDF, 1.65 MB

english, 1989

49

1011-110 The HNO/nitric oxide donor Angeli's salt enhances myocyte contractility in a PKA-dependent manner

Carlo G Tocchetti, Tatsuo Katori, Manuela Zaccolo, Daniele Mancardi, Diego F Belardi, Katrina M Miranda, David A Wink, David A Kass, Nazareno Paolocci

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 95 KB

english, 2004

50

β-Oestradiol rescues ΔF508CFTR functional expression in human cystic fibrosis airway CFBE41o− cells through the up-regulation of NHERF1

Teresa Fanelli, Rosa Angela Cardone, Maria Favia, Lorenzo Guerra, Manuela Zaccolo, Stefania Monterisi, Teresa De Santis, Stefania Maria Riccardi, Stephan Joel Reshkin, Valeria Casavola

Journal:

Biology of the Cell

Year:

2008

Language:

english

File:

PDF, 698 KB

english, 2008

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