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51

MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells

Salmond, R. J., Emery, J., Okkenhaug, K., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.67 MB

english, 2009

52

Early Growth Response (Egr)-1 Gene Induction in the Thymus in Response to TCR Ligation During Early Steps in Positive Selection Is Not Required for CD8 Lineage Commitment

Basson, M. A., Wilson, T. J., Legname, G. A., Sarner, N., Tomlinson, P. D., Tybulewicz, V. L. J., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 1.10 MB

english, 2000

53

TCR Signals Mediated by Src Family Kinases Are Essential for the Survival of Naive T Cells

Seddon, B., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 494 KB

english, 2002

54

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF- B pathways

Costello, P. S., Walters, A. E., Mee, P. J., Turner, M., Reynolds, L. F., Prisco, A., Sarner, N., Zamoyska, R., Tybulewicz, V. L. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 306 KB

english, 1999

55

Differential requirement for Lck during primary and memory CD8+ T cell responses

Tewari, K., Walent, J., Svaren, J., Zamoyska, R., Suresh, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.11 MB

english, 2006

56

Fyn Regulates the Duration of TCR Engagement Needed for Commitment to Effector Function

Filby, A., Seddon, B., Kleczkowska, J., Salmond, R., Tomlinson, P., Smida, M., Lindquist, J. A., Schraven, B., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 664 KB

english, 2007

57

Lyp/PTPN22 is a negative regulator of integrin mediated T cell adhesion and migration; the disease associated PTPN22 allelic variant is a loss of function mutant that perturbs T cell migration

Svensson, L., Burn, G., Sanchez-Blanco, C., Zamoyska, R., Cope, A.

Journal:

Annals of the Rheumatic Diseases

Year:

2011

Language:

english

File:

PDF, 82 KB

english, 2011

58

Centrosome docking at the immunological synapse is controlled by Lck signaling

Tsun, A., Qureshi, I., Stinchcombe, J. C., Jenkins, M. R., de la Roche, M., Kleczkowska, J., Zamoyska, R., Griffiths, G. M.

Journal:

The Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 3.11 MB

english, 2011

59

Involvement of Avidity for Major Histocompatibility Complex in Homeostasis of Naive and Memory T Cells

Kassiotis, G., Zamoyska, R., Stockinger, B.

Journal:

Journal of Experimental Medicine

Year:

2003

Language:

english

File:

PDF, 242 KB

english, 2003

60

CD3 Ligation on Immature Thymocytes Generates Antagonist-like Signals Appropriate for CD8 Lineage Commitment, Independently of T Cell Receptor Specificity

Albert Basson, M., Bommhardt, U., Cole, M. S., Tso, J. Y., Zamoyska, R.

Journal:

Journal of Experimental Medicine

Year:

1998

Language:

english

File:

PDF, 352 KB

english, 1998

61

Lack of the Phosphatase PTPN22 Increases Adhesion of Murine Regulatory T Cells to Improve Their Immunosuppressive Function

Brownlie, R. J., Miosge, L. A., Vassilakos, D., Svensson, L. M., Cope, A., Zamoyska, R.

Journal:

Science Signaling

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

62

Reduced Functional Avidity Promotes Central and Effector Memory CD4 T Cell Responses to Tumor-Associated Antigens

Caserta, S., Kleczkowska, J., Mondino, A., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 2.50 MB

english, 2010

63

Differential Survival of Naive CD4 and CD8 T Cells

Ferreira, C., Barthlott, T., Garcia, S., Zamoyska, R., Stockinger, B.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

64

An Essential Role for the Stalk Region of CD8 in the Coreceptor Function of CD8

Rettig, L., McNeill, L., Sarner, N., Guillaume, P., Luescher, I., Tolaini, M., Kioussis, D., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 576 KB

english, 2009

65

TCR and IL-7 Receptor Signals Can Operate Independently or Synergize to Promote Lymphopenia-Induced Expansion of Naive T Cells

Seddon, B., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 458 KB

english, 2002

66

Unprimed T cells are inefficiently stimulated by glycosylphosphatidylinositol-linked H-2K b because of its lipid anchor rather than defects in CD8 binding

Zamoyska, Rose, Ong, Tim, Kwan-Lim, Gek, Tomlinson, Peter, Robinson, Peter J.

Journal:

International Immunology

Year:

1996

Language:

english

File:

PDF, 2.32 MB

english, 1996

67

Phosphorylation of murine CD8α is not essential for responses of T cell hybridomas to antigen

Williams, Owen, Vukmanovic, Stanislav, Zamoyska, Rose

Journal:

International Immunology

Year:

1991

Language:

english

File:

PDF, 3.41 MB

english, 1991

68

Is CD8 dependence a true reflection of TCR affinity for antigen?

Kwan-Lim, Gek-Eng, Ong, Tim, Aosai, Fumie, Stauss, Hans, Zamoyska, Rose

Journal:

International Immunology

Year:

1993

Language:

english

File:

PDF, 914 KB

english, 1993

69

Superantigens: Supersignalers?

Journal:

Year:

2006

Language:

english

File:

PDF, 398 KB

english, 2006

70

Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation

Salmond, R. J., Brownlie, R. J., Meyuhas, O., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 2.10 MB

english, 2015

71

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice

Sood, S., Brownlie, R. J., Garcia, C., Cowan, G., Salmond, R. J., Sakaguchi, S., Zamoyska, R.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

72

MEK Activity Regulates Negative Selection of Immature CD4+CD8+ Thymocytes

Bommhardt, U., Scheuring, Y., Bickel, C., Zamoyska, R., Hunig, T.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 998 KB

english, 2000

73

IL-12 Signals through the TCR To Support CD8 Innate Immune Responses

Goplen, N. P., Saxena, V., Knudson, K. M., Schrum, A. G., Gil, D., Daniels, M. A., Zamoyska, R., Teixeiro, E.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

74

PTPN22 Is a Critical Regulator of Fc Receptor-Mediated Neutrophil Activation

Vermeren, S., Miles, K., Chu, J. Y., Salter, D., Zamoyska, R., Gray, M.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

75

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

Watson, Rebecca L., McNeilly, Tom N., Watt, Kathryn A., Pemberton, Josephine M., Pilkington, Jill G., Waterfall, Martin, Hopper, Phoebe R.T., Cooney, Daniel, Zamoyska, Rose, Nussey, Daniel H.

Journal:

Ecology and Evolution

Year:

2016

Language:

english

File:

PDF, 741 KB

english, 2016

76

Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

Borger, Jessica G., Morrison, Vicky L., Filby, Andrew, Garcia, Celine, Uotila, Liisa M., Simbari, Fabio, Fagerholm, Susanna C., Zamoyska, Rose

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.81 MB

english, 2017

77

Protein Tyrosine Phosphatase PTPN22 regulates IL-1β dependent Th17 responses by modulating dectin-1 signaling in mice

Purvis, Harriet A, Clarke, Fiona, Jordan, Christine K, Blanco, Cristina Sanchez, Cornish, Georgina H, Dai, Xuezhi, Rawlings, David J, Zamoyska, Rose, Cope, Andrew P

Journal:

European Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

78

Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22

Brownlie, Rebecca J., Garcia, Celine, Ravasz, Mate, Zehn, Dietmar, Salmond, Robert J., Zamoyska, Rose

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

79

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, 14–17 June, 2017 - ()] Oral Presentations - OP0296 Autoimmune associated gene PTPN22 negatively regulates DECTIN-1 signalling in dendritic cells

Purvis, H, Clarke, F, Jordan, C, Sanchez-Blanco, C, Cornish, GH, Rawlings, D, Zamoyska, R, Cope, AP

Language:

english

File:

PDF, 209 KB

english

80

Regulation of autoimmune and anti-tumour T cell responses by PTPN22

Brownlie, Rebecca J., Zamoyska, Rose, Salmond, Robert J.

Journal:

Year:

2018

Language:

english

File:

PDF, 523 KB

english, 2018

81

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses

Sanchez-Blanco, Cristina, Clarke, Fiona, Cornish, Georgina H., Depoil, David, Thompson, Stephen J., Dai, Xuezhi, Rawlings, David J., Dustin, Michael L., Zamoyska, Rose, Cope, Andrew P., Purvis, Harrie

Journal:

Journal of Autoimmunity

Year:

2018

Language:

english

File:

PDF, 1.74 MB

english, 2018

82

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens

Clarke, Fiona, Purvis, Harriet A., Sanchez-Blanco, Cristina, Gutiérrez-Martinez, Enrique, Cornish, Georgina H., Zamoyska, Rose, Guermonprez, Pierre, Cope, Andrew P.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.94 MB

english, 2018

83

Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2

Bray, Cara, Wright, David, Haupt, Sonja, Thomas, Sharyn, Stauss, Hans, Zamoyska, Rose

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

84

PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion

Knipper, Johanna A., Wright, David, Cope, Andrew P., Malissen, Bernard, Zamoyska, Rose

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 3.67 MB

2020

85

Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

Purvis, Harriet A., Clarke, Fiona, Montgomery, Anna B., Colas, Chloe, Bibby, Jack A., Cornish, Georgina H., Dai, Xuezhi, Dudziak, Diana, Rawlings, David J., Zamoyska, Rose, Guermonprez, Pierre, Cope,

Journal:

Frontiers in Immunology

Year:

2020

Language:

english

File:

PDF, 1.04 MB

english, 2020

86

Central and Effector Memory CD4 and CD8 T-Cell Responses to Tumor-Associated Antigens

Caserta, Stefano, Borger, Jessica Geraldine, Zamoyska, Rose

Journal:

Critical Reviews™ in Immunology

Year:

2012

File:

PDF, 1.48 MB

2012

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