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1

Generation of C5a in the absence of C3: a new complement activation pathway

Huber-Lang, Markus, Sarma, J Vidya, Zetoune, Firas S, Rittirsch, Daniel, Neff, Thomas A, McGuire, Stephanie R, Lambris, John D, Warner, Roscoe L, Flierl, Michael A, Hoesel, Laszlo M

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 377 KB

english, 2006

2

Regulation of IL-17 Family Members by Adrenal Hormones During Experimental Sepsis in Mice

Bosmann, Markus, Meta, Fabien, Ruemmler, Robert, Haggadone, Mikel D., Sarma, J. Vidya, Zetoune, Firas S., Ward, Peter A.

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 812 KB

english, 2013

3

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

Bosmann, M., Grailer, J. J., Ruemmler, R., Russkamp, N. F., Zetoune, F. S., Sarma, J. V., Standiford, T. J., Ward, P. A.

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 794 KB

english, 2013

4

Regulatory Role of C5a on Macrophage Migration Inhibitory Factor Release from Neutrophils

Riedemann, N. C., Guo, R.-F., Gao, H., Sun, L., Hoesel, M., Hollmann, T. J., Wetsel, R. A., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

5

The 185delAG mutation (c.68_69delAG) in the BRCA1 gene triggers translation reinitiation at a downstream AUG codon

Monique Buisson, Olga Anczuków, Almoutassem B. Zetoune, Mark D. Ware, Sylvie Mazoyer

Journal:

Year:

2006

Language:

english

File:

PDF, 243 KB

english, 2006

6

Does the nonsense-mediated mRNA decay mechanism prevent the synthesis of truncated BRCA1, CHK2, and p53 proteins?

Olga Anczuków, Mark D. Ware, Monique Buisson, Almoutassem B. Zetoune, Dominique Stoppa-Lyonnet, Olga M. Sinilnikova, Sylvie Mazoyer

Journal:

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

7

Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

Almoutassem B Zetoune, Sandra Fontanière, Delphine Magnin, Olga Anczuków, Monique Buisson, Chang X Zhang, Sylvie Mazoyer

Journal:

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

8

Phagocyte-derived catecholamines enhance acute inflammatory injury

McGuire, Stephanie R., List, Rachel P., Day, Danielle E., Hoesel, L. Marco, Flierl, Michael A., Rittirsch, Daniel, Nadeau, Brian A., Chen, Anthony J., Sarma, J. Vidya, Zetoune, Firas S.

Journal:

Year:

2007

Language:

english

File:

PDF, 538 KB

english, 2007

9

Functional roles for C5a receptors in sepsis

Rittirsch, Daniel, Flierl, Michael A, Nadeau, Brian A, Day, Danielle E, Huber-Lang, Markus, Mackay, Charles R, Zetoune, Firas S, Gerard, Norma P, Cianflone, Katherine, Köhl, Jörg

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 303 KB

english, 2008

10

NRADD, a novel membrane protein with a death domain involved in mediating apoptosis in response to ER stress

Wang, X, Shao, Z, Zetoune, F S, Zeidler, M G, Gowrishankar, K, Vincenz, C

Journal:

Cell Death & Differentiation

Year:

2003

Language:

english

File:

PDF, 407 KB

english, 2003

11

Prophylactic Central Neck Dissection and Local Recurrence in Papillary Thyroid Cancer: A Meta-analysis

Tarek Zetoune, Xavier Keutgen, Daniel Buitrago, Hasan Aldailami, Huibo Shao, Madhu Mazumdar, Thomas J. Fahey, Rasa Zarnegar

Journal:

Annals of Surgical Oncology

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

12

Low dicer expression correlates with aggressive features in thyroid cancer

Xavier M. Keutgen, Tarek Zetoune, Daniel Buitrago, Hasan Aldailami, Rasa Zarnegar

Journal:

Journal of the American College of Surgeons

Year:

2010

Language:

english

File:

PDF, 90 KB

english, 2010

13

A20 INHIBITS NF-κB ACTIVATION DOWNSTREAM OF MULTIPLE MAP3 KINASES AND INTERACTS WITH THE IκB SIGNALOSOME

Firas S. Zetoune, Anita R. Murthy, Zhihong Shao, Tom Hlaing, Michael G. Zeidler, Yong Li, Claudius Vincenz

Journal:

Year:

2001

Language:

english

File:

PDF, 2.24 MB

english, 2001

14

Complement C5a signaling dependent production of IL-17 during sepsis

Hongwei Gao, Thomas A. Neff, L. Marco Hoesel, Ren-Feng Guo, Lei Sun, Michael A. Flierl, J. Vidya Sarma, Firas S. Zetoune, Peter A. Ward

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

15

Influence of C5a on neutrophil behavior during sepsis

Ren-Feng Guo, Hongwei Gao, Kevin X. Shi, Vidya J. Sarma, Firas S. Zetoune, Peter A. Ward

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 74 KB

english, 2007

16

Generation of C5a in the absence of C3: A new complement activation pathway

J. Vidya Sarma, Markus Huber-Lang, Firas S. Zetoune, Daniel Rittirsch, John D. Lambris, Scott M. Drouin, Rick A. Wetsel, Peter A. Ward

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 78 KB

english, 2007

17

C5a, C5aR and septic cardiomyopathy

Peter A. Ward, Laszlo M. Hoesel, Andreas D. Neiderbichler, Michael A. Flierl, Daniel Rittirsch, Firas S. Zetoune

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 72 KB

english, 2007

18

Immunopathogenesis of lipopolysaccharide- and IgG immune complex-induced acute lung injury in rodents

J. Vidya Sarma, Daniel Rittirsch, Michael A. Flierl, Firas S. Zetoune, Brian A. Nadeau, Thomas A. Neff, Markus S. Huber-Lang, Peter A. Ward

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

19

C5aR negatively regulates in vivo and in vitro production of IL-17A

Peter A. Ward, Markus Bosmann, J. Vidya Sarma, Ketong Zhu, Firas S. Zetoune

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 70 KB

english, 2010

20

Generation of C5a by Phagocytic Cells

Markus Huber-Lang, Ellen M. Younkin, J. Vidya Sarma, Niels Riedemann, Stephanie R. McGuire, Kristina T. Lu, Robin Kunkel, John G. Younger, Firas S. Zetoune, Peter A. Ward

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 622 KB

english, 2002

21

Regulation by C5a of Neutrophil Activation during Sepsis

Niels C. Riedemann, Ren-Feng Guo, Kurt D. Bernacki, Jayne S. Reuben, Ines J. Laudes, Thomas A. Neff, Hongwei Gao, Cecilia Speyer, Vidya J. Sarma, Firas S. Zetoune, Peter A. Ward

Journal:

Year:

2003

Language:

english

File:

PDF, 412 KB

english, 2003

22

Complement Activation Product C5a Is a Selective Suppressor of TLR4-Induced, but Not TLR3-Induced, Production of IL-27(p28) from Macrophages

Bosmann, M., Haggadone, M. D., Hemmila, M. R., Zetoune, F. S., Sarma, J. V., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 815 KB

english, 2012

23

Critical Role for the NLRP3 Inflammasome during Acute Lung Injury

Grailer, J. J., Canning, B. A., Kalbitz, M., Haggadone, M. D., Dhond, R. M., Andjelkovic, A. V., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

24

In vivo regulation of neutrophil apoptosis by C5a during sepsis

Guo, R.-F., Sun, L., Gao, H., Shi, K. X., Rittirsch, D., Sarma, V. J., Zetoune, F. S., Ward, P. A.

Journal:

Journal of Leukocyte Biology

Year:

2006

Language:

english

File:

PDF, 460 KB

english, 2006

25

Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

Bosmann, M., Sarma, J. V., Atefi, G., Zetoune, F. S., Ward, P. A.

Journal:

The FASEB Journal

Year:

2012

Language:

english

File:

PDF, 575 KB

english, 2012

26

Dicer expression and microRNA dysregulation associate with aggressive features in thyroid cancer

Erler, Piril, Keutgen, Xavier M., Crowley, Michael J., Zetoune, Tarek, Kundel, Anna, Kleiman, David, Beninato, Toni, Scognamiglio, Theresa, Elemento, Olivier, Zarnegar, Rasa, Fahey, Thomas J.

Journal:

Year:

2014

Language:

english

File:

PDF, 1002 KB

english, 2014

27

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation

Bosmann, Markus, Haggadone, Mikel D., Zetoune, Firas S., Sarma, J. Vidya, Ward, Peter A.

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 489 KB

english, 2013

28

xPharm: The Comprehensive Pharmacology Reference || Inflammatory Disorders

Zetoune, Firas S.

Year:

2007

Language:

english

File:

PDF, 73 KB

english, 2007

29

Anti-complement Strategies in Experimental Sepsis

Ward, Peter A., Riedemann, Niels C., Guo, Ren-feng, Huber-lang, Markus, Sarma, J. Vidya, Zetoune, Firas S.

Journal:

Scandinavian Journal of Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 66 KB

english, 2003

30

Interruption of Macrophage-Derived IL-27(p28) Production by IL-10 during Sepsis Requires STAT3 but Not SOCS3

Bosmann, M., Russkamp, N. F., Strobl, B., Roewe, J., Balouzian, L., Pache, F., Radsak, M. P., van Rooijen, N., Zetoune, F. S., Sarma, J. V., Nunez, G., Muller, M., Murray, P. J., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

31

Functions of the complement components C3 and C5 during sepsis

Flierl, M. A., Rittirsch, D., Nadeau, B. A., Day, D. E., Zetoune, F. S., Sarma, J. V., Huber-Lang, M. S., Ward, P. A.

Journal:

The FASEB Journal

Year:

2008

Language:

english

File:

PDF, 345 KB

english, 2008

32

Expression and Function of C5a Receptor in Mouse Microvascular Endothelial Cells

Laudes, I. J., Chu, J. C., Huber-Lang, M., Guo, R.-F., Riedemann, N. C., Sarma, J. V., Mahdi, F., Murphy, H. S., Speyer, C., Lu, K. T., Lambris, J. D., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 604 KB

english, 2002

33

Cutting Edge: Critical Role for C5aRs in the Development of Septic Lymphopenia in Mice

Grailer, J. J., Fattahi, F., Dick, R. S., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

34

Anti-inflammatory effects of 2 adrenergic receptor agonists in experimental acute lung injury

Bosmann, M., Grailer, J. J., Zhu, K., Matthay, M. A., Sarma, J. V., Zetoune, F. S., Ward, P. A.

Journal:

The FASEB Journal

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

35

Role of extracellular histones in the cardiomyopathy of sepsis

Kalbitz, M., Grailer, J. J., Fattahi, F., Jajou, L., Herron, T. J., Campbell, K. F., Zetoune, F. S., Bosmann, M., Sarma, J. V., Huber-Lang, M., Gebhard, F., Loaiza, R., Valdivia, H. H., Jalife, J., Ru

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

36

Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system

Rittirsch, D., Flierl, M. A., Nadeau, B. A., Day, D. E., Huber-Lang, M. S., Grailer, J. J., Zetoune, F. S., Andjelkovic, A. V., Fasano, A., Ward, P. A.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2013

Language:

english

File:

PDF, 1.66 MB

english, 2013

37

Characterization of a p75NTR Apoptotic Signaling Pathway Using a Novel Cellular Model

Wang, X., Bauer, J. H., Li, Y., Shao, Z., Zetoune, F. S., Cattaneo, E., Vincenz, C.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 838 KB

english, 2001

38

Changes in the Novel Orphan, C5a Receptor (C5L2), during Experimental Sepsis and Sepsis in Humans

Huber-Lang, M., Sarma, J. V., Rittirsch, D., Schreiber, H., Weiss, M., Flierl, M., Younkin, E., Schneider, M., Suger-Wiedeck, H., Gebhard, F., McClintock, S. D., Neff, T., Zetoune, F., Bruckner, U., G

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 475 KB

english, 2005

39

Divergent Signaling Pathways in Phagocytic Cells during Sepsis

Guo, R.-F., Riedemann, N. C., Sun, L., Gao, H., Shi, K. X., Reuben, J. S., Sarma, V. J., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 793 KB

english, 2006

40

Structure-Function Relationships of Human C5a and C5aR

Huber-Lang, M. S., Sarma, J. V., McGuire, S. R., Lu, K. T., Padgaonkar, V. A., Younkin, E. M., Guo, R. F., Weber, C. H., Zuiderweg, E. R., Zetoune, F. S., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 1020 KB

english, 2003

41

Organ distribution of histones after intravenous infusion of FITC histones or after sepsis

Fattahi, Fatemeh, Grailer, Jamison J., Jajou, Lawrence, Zetoune, Firas S., Andjelkovic, Anuska V., Ward, Peter A.

Journal:

Immunologic Research

Year:

2015

Language:

english

File:

PDF, 4.70 MB

english, 2015

42

Complement dependency of cardiomyocyte release of mediators during sepsis

Atefi, G., Zetoune, F. S., Herron, T. J., Jalife, J., Bosmann, M., Al-Aref, R., Sarma, J. V., Ward, P. A.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 444 KB

english, 2011

43

Adverse functions of IL-17A in experimental sepsis

Flierl, M. A., Rittirsch, D., Gao, H., Hoesel, L. M., Nadeau, B. A., Day, D. E., Zetoune, F. S., Sarma, J. V., Huber-Lang, M. S., Ferrara, J. L. M., Ward, P. A.

Journal:

The FASEB Journal

Year:

2008

Language:

english

File:

PDF, 452 KB

english, 2008

44

Persistent Neutrophil Dysfunction and Suppression of Acute Lung Injury in Mice following Cecal Ligation and Puncture Sepsis

Grailer, Jamison J., Kalbitz, Miriam, Zetoune, Firas S., Ward, Peter A.

Journal:

Journal of Innate Immunity

Year:

2014

Language:

english

File:

PDF, 656 KB

english, 2014

45

Induction of M2 Regulatory Macrophages through the � 2 -Adrenergic Receptor with Protection during Endotoxemia and Acute Lung Injury

Grailer, Jamison J., Haggadone, Mikel D., Sarma, J. Vidya, Zetoune, Firas S., Ward, Peter A.

Journal:

Journal of Innate Immunity

Year:

2014

Language:

english

File:

PDF, 725 KB

english, 2014

46

MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway

Bosmann, M., Patel, V. R., Russkamp, N. F., Pache, F., Zetoune, F. S., Sarma, J. V., Ward, P. A.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 503 KB

english, 2011

47

Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

Unnewehr, H., Rittirsch, D., Sarma, J. V., Zetoune, F., Flierl, M. A., Perl, M., Denk, S., Weiss, M., Schneider, M. E., Monk, P. N., Neff, T., Mihlan, M., Barth, H., Gebhard, F., Ward, P. A., Huber-La

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 788 KB

english, 2013

48

Acute Lung Injury Induced by Lipopolysaccharide Is Independent of Complement Activation

Rittirsch, D., Flierl, M. A., Day, D. E., Nadeau, B. A., McGuire, S. R., Hoesel, L. M., Ipaktchi, K., Zetoune, F. S., Sarma, J. V., Leng, L., Huber-Lang, M. S., Neff, T. A., Bucala, R., Ward, P. A.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 544 KB

english, 2008

49

Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells

Sun, L., Guo, R.-F., Gao, H., Sarma, J. V., Zetoune, F. S., Ward, P. A.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

50

CD11c+ Alveolar Macrophages are a Source of IL-23 During Lipopolysaccharide-Induced Acute Lung Injury

Bosmann, Markus, Grailer, Jamison J., Russkamp, Norman F., Ruemmler, Robert, Zetoune, Firas S., Sarma, J. Vidya, Ward, Peter A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013